IMPPAT Phytochemical information: 
Chelerythrine
Chelerythrine
Summary

SMILES: COc1c(OC)ccc2c1c[n+](C)c1c2ccc2c1cc1OCOc1c2
InChI: InChI=1S/C21H18NO4/c1-22-10-16-13(6-7-17(23-2)21(16)24-3)14-5-4-12-8-18-19(26-11-25-18)9-15(12)20(14)22/h4-10H,11H2,1-3H3/q+1
InChIKey: LLEJIEBFSOEYIV-UHFFFAOYSA-N
DeepSMILES: COccOC))cccc6c[n+]C)cc6cccc6ccOCOc5c9
Scaffold Graph/Node/Bond level: c1ccc2c(c1)c[nH+]c1c3cc4c(cc3ccc21)OCO4
Scaffold Graph/Node level: C1CCC2C(C1)CNC1C3CC4OCOC4CC3CCC21
Scaffold Graph level: C1CC2CC3CCC4C5CCCCC5CCC4C3CC2C1
Functional groups: cOC; c[n+](C)c; c1cOCO1
Chemical classification
ClassyFire Kingdom: Organic compounds
ClassyFire Superclass: Alkaloids and derivatives
ClassyFire Class: Benzophenanthridine alkaloids
ClassyFire Subclass: Quaternary benzophenanthridine alkaloids
Synonymous chemical names:
chelerythrine, toddaline(chelerythrine)
External chemical identifiers:
CID:CID_2703; ChEMBL:CHEMBL13045; ChEBI:CHEBI:78373; ZINC:ZINC000003872044; FDASRS:E3B045W6X0; SureChEMBL:SCHEMBL288915; MolPort-006-106-669
Chemical structure download
2D:2D MOL2D MOL22D SDF
3D:3D MOL3D MOL23D SDF3D PDB3D PDBQT
Chelerythrine
Physicochemical properties
Property name Tool Property value
Molecular weight (g/mol) RDKit 348.38
Log P RDKit 3.72
Topological polar surface area (Å2) RDKit 40.8
Number of hydrogen bond acceptors RDKit 4
Number of hydrogen bond donors RDKit 0
Number of carbon atoms RDKit 21
Number of heavy atoms RDKit 26
Number of heteroatoms RDKit 5
Number of nitrogen atoms RDKit 1
Number of sulfur atoms RDKit 0
Number of chiral carbon atoms RDKit 0
Stereochemical complexity RDKit 0
Number of sp hybridized carbon atoms RDKit 0
Number of sp2 hybridized carbon atoms RDKit 17
Number of sp3 hybridized carbon atoms RDKit 4
Shape complexity RDKit 0.19
Number of rotatable bonds RDKit 2
Number of aliphatic carbocycles RDKit 0
Number of aliphatic heterocycles RDKit 1
Number of aliphatic rings RDKit 1
Number of aromatic carbocycles RDKit 3
Number of aromatic heterocycles RDKit 1
Number of aromatic rings RDKit 4
Total number of rings RDKit 5
Number of saturated carbocycles RDKit 0
Number of saturated heterocycles RDKit 0
Number of saturated rings RDKit 0
Number of Smallest Set of Smallest Rings (SSSR) RDKit 5
Chelerythrine
Drug-likeness
Property nameToolProperty value
Number of Lipinski’s rule of 5 violations RDKit 0
Lipinski’s rule of 5 filter RDKit Passed
Number of Ghose filter violations RDKit 0
Ghose filter RDKit Passed
Veber filter RDKit Good
Pfizer 3/75 filter RDKit Bad
GSK 4/400 filter RDKit Good
Weighted quantitative estimate of drug-likeness (QEDw) score RDKit 0.408941
Chelerythrine
ADME properties
Property nameToolProperty value
Bioavailability score SwissADME 0.55
Solubility class [ESOL] SwissADME Moderately soluble
Solubility class [Silicos-IT] SwissADME Poorly soluble
Blood Brain Barrier permeation SwissADME Yes
Gastrointestinal absorption SwissADME High
Log Kp (Skin permeation, cm/s) SwissADME -5.17
Number of PAINS structural alerts SwissADME 0
Number of Brenk structural alerts SwissADME 2
CYP1A2 inhibitor SwissADME Yes
CYP2C19 inhibitor SwissADME Yes
CYP2C9 inhibitor SwissADME Yes
CYP2D6 inhibitor SwissADME No
CYP3A4 inhibitor SwissADME Yes
P-glycoprotein substrate SwissADME Yes
Chelerythrine
Phytochemical - Human target proteins supported by experimental evidence associations
Human target proteins supported by experimental evidence
IMPPAT target identifierGene identifierHGNC symbolEntrez Gene identifierSource
TAR_EXP_000880ENSG00000118058KMT2A4297NPASS
TAR_EXP_000881ENSG00000087085ACHE43BindingDB, ChEMBL, NPASS
TAR_EXP_000903ENSG00000164078MST1R4486ChEMBL, NPASS
TAR_EXP_000917ENSG00000030304MUSK4593ChEMBL, NPASS
TAR_EXP_000920ENSG00000065534MYLK4638ChEMBL, NPASS
TAR_EXP_000959ENSG00000117650NEK24751ChEMBL, NPASS
TAR_EXP_000960ENSG00000136098NEK34752ChEMBL, NPASS
TAR_EXP_000966ENSG00000116044NFE2L24780NPASS
TAR_EXP_001480ENSG00000136573BLK640ChEMBL, NPASS
TAR_EXP_001492ENSG00000118515SGK16446ChEMBL, NPASS
TAR_EXP_001514ENSG00000196632WNK365267ChEMBL, NPASS
TAR_EXP_001515ENSG00000165238WNK265268ChEMBL, NPASS
TAR_EXP_000715ENSG00000044574HSPA53309NPASS
TAR_EXP_000706ENSG00000291796APEX1328NPASS
TAR_EXP_001545ENSG00000130413STK3365975ChEMBL, NPASS
TAR_EXP_000878ENSG00000006432MAP3K94293ChEMBL, NPASS
TAR_EXP_000874ENSG00000105976MET4233ChEMBL, NPASS
TAR_EXP_000785ENSG00000105639JAK33718ChEMBL, NPASS
TAR_EXP_000858ENSG00000198355PIM3415116ChEMBL, NPASS
TAR_EXP_000784ENSG00000096968JAK23717ChEMBL, NPASS
TAR_EXP_000782ENSG00000113263ITK3702ChEMBL, NPASS
TAR_EXP_000772ENSG00000184216IRAK13654ChEMBL, NPASS
TAR_EXP_000771ENSG00000027644INSRR3645ChEMBL, NPASS
TAR_EXP_000770ENSG00000171105INSR3643ChEMBL, NPASS
TAR_EXP_000755ENSG00000104365IKBKB3551ChEMBL, NPASS
TAR_EXP_000750ENSG00000140443IGF1R3480ChEMBL, NPASS
TAR_EXP_000810ENSG00000128052KDR3791ChEMBL, NPASS
TAR_EXP_000811ENSG00000157404KIT3815ChEMBL, NPASS
TAR_EXP_000831ENSG00000106683LIMK13984ChEMBL, NPASS
TAR_EXP_000842ENSG00000254087LYN4067ChEMBL, NPASS
TAR_EXP_000846ENSG00000100299ARSA410NPASS
TAR_EXP_000851ENSG00000189221MAOA4128ChEMBL, NPASS
TAR_EXP_000852ENSG00000069535MAOB4129ChEMBL, NPASS
TAR_EXP_000853ENSG00000276155MAPT4137ChEMBL, NPASS
TAR_EXP_000854ENSG00000116141MARK14139ChEMBL, NPASS
TAR_EXP_000822ENSG00000182866LCK3932ChEMBL, NPASS
TAR_EXP_000872ENSG00000197442MAP3K54217ChEMBL, NPASS
TAR_EXP_000304ENSG00000170390DCLK2166614ChEMBL, NPASS
TAR_EXP_001547ENSG00000275349SMN16606NPASS
TAR_EXP_001740ENSG00000152495CAMK4814ChEMBL, NPASS
TAR_EXP_001743ENSG00000058404CAMK2B816ChEMBL, NPASS
TAR_EXP_001744ENSG00000145349CAMK2D817ChEMBL, NPASS
TAR_EXP_001746ENSG00000148660CAMK2G818ChEMBL, NPASS
TAR_EXP_001760ENSG00000177602HASPIN83903ChEMBL, NPASS
TAR_EXP_001762ENSG00000212122TSSK1B83942ChEMBL, NPASS
TAR_EXP_001769ENSG00000102572STK248428ChEMBL, NPASS
TAR_EXP_001774ENSG00000160469BRSK184446ChEMBL, NPASS
TAR_EXP_001775ENSG00000127334DYRK28445ChEMBL, NPASS
TAR_EXP_001781ENSG00000143776CDC42BPA8476ChEMBL, NPASS
TAR_EXP_001793ENSG00000134072CAMK18536ChEMBL, NPASS
TAR_EXP_001728ENSG00000176208ATAD579915NPASS
TAR_EXP_001796ENSG00000089022MAPKAPK58550ChEMBL, NPASS
TAR_EXP_001834ENSG00000176749CDK5R18851ChEMBL, NPASS
TAR_EXP_001843ENSG00000145386CCNA2890ChEMBL
TAR_EXP_001844ENSG00000133101CCNA18900ChEMBL, NPASS
TAR_EXP_001845ENSG00000134057CCNB1891ChEMBL, NPASS
TAR_EXP_001850ENSG00000112576CCND3896ChEMBL
TAR_EXP_001853ENSG00000105173CCNE1898ChEMBL
TAR_EXP_001855ENSG00000162302RPS6KA48986ChEMBL, NPASS
TAR_EXP_001859ENSG00000134480CCNH902ChEMBL
TAR_EXP_001863ENSG00000129315CCNT1904ChEMBL
TAR_EXP_001868ENSG00000036672USP29099NPASS
TAR_EXP_001869ENSG00000135503ACVR1B91ChEMBL, NPASS
TAR_EXP_001821ENSG00000104312RIPK28767ChEMBL, NPASS
TAR_EXP_001724ENSG00000114670NEK1179858ChEMBL, NPASS
TAR_EXP_001710ENSG00000114738MAPKAPK37867ChEMBL, NPASS
TAR_EXP_001682ENSG00000115085ZAP707535ChEMBL, NPASS
TAR_EXP_000701ENSG00000164120HPGD3248NPASS
TAR_EXP_001554ENSG00000291971SRC6714ChEMBL, NPASS
TAR_EXP_001559ENSG00000096063SRPK16732ChEMBL, NPASS
TAR_EXP_001560ENSG00000135250SRPK26733ChEMBL, NPASS
TAR_EXP_001572ENSG00000104375STK36788ChEMBL, NPASS
TAR_EXP_001573ENSG00000101109STK46789ChEMBL, NPASS
TAR_EXP_001574ENSG00000087586AURKA6790ChEMBL, NPASS
TAR_EXP_001576ENSG00000072786STK106793ChEMBL, NPASS
TAR_EXP_001577ENSG00000118046STK116794ChEMBL, NPASS
TAR_EXP_001578ENSG00000105146AURKC6795ChEMBL, NPASS
TAR_EXP_001584ENSG00000165025SYK6850ChEMBL, NPASS
TAR_EXP_001589ENSG00000135341MAP3K76885ChEMBL, NPASS
TAR_EXP_001593ENSG00000010671BTK695ChEMBL, NPASS
TAR_EXP_001597ENSG00000135605TEC7006ChEMBL, NPASS
TAR_EXP_001598ENSG00000120156TEK7010ChEMBL, NPASS
TAR_EXP_001603ENSG00000106799TGFBR17046ChEMBL, NPASS
TAR_EXP_001607ENSG00000090534THPO7066ChEMBL, NPASS
TAR_EXP_001609ENSG00000151090THRB7068NPASS
TAR_EXP_001621ENSG00000141510TP537157ChEMBL, NPASS
TAR_EXP_001631ENSG00000165409TSHR7253NPASS
TAR_EXP_001643ENSG00000074966TXK7294ChEMBL, NPASS
TAR_EXP_001648ENSG00000092445TYRO37301ChEMBL, NPASS
TAR_EXP_001665ENSG00000111424VDR7421ChEMBL, NPASS
TAR_EXP_001672ENSG00000028116VRK27444ChEMBL, NPASS
TAR_EXP_001680ENSG00000176105YES17525ChEMBL, NPASS
TAR_EXP_001546ENSG00000102010BMX660ChEMBL, NPASS
TAR_EXP_000687ENSG00000100644HIF1A3091NPASS
TAR_EXP_000030ENSG00000061938TNK210188ChEMBL, NPASS
TAR_EXP_000676ENSG00000072506HSD17B103028ChEMBL, NPASS
TAR_EXP_000101ENSG00000102096PIM211040ChEMBL, NPASS
TAR_EXP_000099ENSG00000146872TLK211011ChEMBL, NPASS
TAR_EXP_000097ENSG00000108468CBX110951NPASS
TAR_EXP_000348ENSG00000146648EGFR1956ChEMBL, NPASS
TAR_EXP_000353ENSG00000142627EPHA21969ChEMBL, NPASS
TAR_EXP_000365ENSG00000072518MARK22011ChEMBL, NPASS
TAR_EXP_000372ENSG00000284816EPHA12041ChEMBL, NPASS
TAR_EXP_000373ENSG00000044524EPHA32042ChEMBL, NPASS
TAR_EXP_000374ENSG00000116106EPHA42043ChEMBL, NPASS
TAR_EXP_000375ENSG00000145242EPHA52044ChEMBL, NPASS
TAR_EXP_000376ENSG00000135333EPHA72045ChEMBL, NPASS
TAR_EXP_000377ENSG00000070886EPHA82046ChEMBL, NPASS
TAR_EXP_000378ENSG00000154928EPHB12047ChEMBL, NPASS
TAR_EXP_000379ENSG00000133216EPHB22048ChEMBL, NPASS
TAR_EXP_000380ENSG00000163349HIPK1204851ChEMBL, NPASS
TAR_EXP_000381ENSG00000182580EPHB32049ChEMBL, NPASS
TAR_EXP_000382ENSG00000196411EPHB42050ChEMBL, NPASS
TAR_EXP_001873ENSG00000175305CCNE29134ChEMBL, NPASS
TAR_EXP_000388ENSG00000178568ERBB42066ChEMBL, NPASS
TAR_EXP_000390ENSG00000142208AKT1207ChEMBL, NPASS
TAR_EXP_000393ENSG00000105221AKT2208ChEMBL, NPASS
TAR_EXP_000411ENSG00000165092ALDH1A1216NPASS
TAR_EXP_000422ENSG00000120899PTK2B2185ChEMBL, NPASS
TAR_EXP_000107ENSG00000149554CHEK11111ChEMBL, NPASS
TAR_EXP_000433ENSG00000168496FEN12237NPASS
TAR_EXP_000118ENSG00000183765CHEK211200ChEMBL, NPASS
TAR_EXP_000157ENSG00000213341CHUK1147ChEMBL, NPASS
TAR_EXP_000296ENSG00000132437DDC1644NPASS
TAR_EXP_000291ENSG00000167657DAPK31613ChEMBL, NPASS
TAR_EXP_000290ENSG00000196730DAPK11612ChEMBL, NPASS
TAR_EXP_000280ENSG00000160868CYP3A41576NPASS
TAR_EXP_000276ENSG00000272532CYP2D61565NPASS
TAR_EXP_000273ENSG00000138109CYP2C91559NPASS
TAR_EXP_000271ENSG00000165841CYP2C191557ChEMBL, NPASS
TAR_EXP_000263ENSG00000140505CYP1A21544ChEMBL, NPASS
TAR_EXP_000244ENSG00000142178SIK1150094ChEMBL, NPASS
TAR_EXP_000234ENSG00000230700CSNK2B1460ChEMBL
TAR_EXP_000232ENSG00000070770CSNK2A21459ChEMBL, NPASS
TAR_EXP_000231ENSG00000101266CSNK2A11457ChEMBL
TAR_EXP_000230ENSG00000151292CSNK1G31456ChEMBL, NPASS
TAR_EXP_000229ENSG00000133275CSNK1G21455ChEMBL, NPASS
TAR_EXP_000227ENSG00000141551CSNK1D1453ChEMBL, NPASS
TAR_EXP_000225ENSG00000103653CSK1445ChEMBL, NPASS
TAR_EXP_000224ENSG00000182578CSF1R1436ChEMBL, NPASS
TAR_EXP_000222ENSG00000112062MAPK141432ChEMBL, NPASS
TAR_EXP_000215ENSG00000151414NEK7140609ChEMBL, NPASS
TAR_EXP_000196ENSG00000114124GRK7131890ChEMBL, NPASS
TAR_EXP_000185ENSG00000173846PLK31263ChEMBL, NPASS
TAR_EXP_000169ENSG00000179335CLK31198ChEMBL, NPASS
TAR_EXP_000168ENSG00000176444CLK21196ChEMBL, NPASS
TAR_EXP_000132ENSG00000137491SLCO2B111309ChEMBL, NPASS
TAR_EXP_000434ENSG00000151422FER2241ChEMBL, NPASS
TAR_EXP_000435ENSG00000182511FES2242ChEMBL, NPASS
TAR_EXP_000438ENSG00000077782FGFR12260ChEMBL, NPASS
TAR_EXP_000557ENSG00000140474ULK325989ChEMBL, NPASS
TAR_EXP_000572ENSG00000108773KAT2A2648NPASS
TAR_EXP_000574ENSG00000184343SRPK326576ChEMBL, NPASS
TAR_EXP_000580ENSG00000143322ABL227ChEMBL, NPASS
TAR_EXP_000598ENSG00000072133RPS6KA627330ChEMBL, NPASS
TAR_EXP_000616ENSG00000111700SLCO1B328234ChEMBL, NPASS
TAR_EXP_000632ENSG00000198873GRK52869ChEMBL, NPASS
TAR_EXP_000633ENSG00000198055GRK62870ChEMBL, NPASS
TAR_EXP_000634ENSG00000099875MKNK22872ChEMBL, NPASS
TAR_EXP_000636ENSG00000064393HIPK228996ChEMBL, NPASS
TAR_EXP_000647ENSG00000183735TBK129110ChEMBL, NPASS
TAR_EXP_000659ENSG00000105723GSK3A2931ChEMBL, NPASS
TAR_EXP_000660ENSG00000082701GSK3B2932ChEMBL, NPASS
TAR_EXP_000036ENSG00000277273CDK71022ChEMBL, NPASS
TAR_EXP_000034ENSG00000105810CDK61021ChEMBL, NPASS
TAR_EXP_000032ENSG00000164885CDK51020ChEMBL
TAR_EXP_000316ENSG00000104936DMPK1760ChEMBL, NPASS
TAR_EXP_000029ENSG00000250506CDK31018ChEMBL, NPASS
TAR_EXP_000027ENSG00000123374CDK21017ChEMBL
TAR_EXP_000023ENSG00000110422HIPK310114ChEMBL, NPASS
TAR_EXP_000022ENSG00000101049SGK210110ChEMBL, NPASS
TAR_EXP_000002ENSG00000117020AKT310000ChEMBL, NPASS
TAR_EXP_000671ENSG00000103319EEF2K29904ChEMBL, NPASS
TAR_EXP_000546ENSG00000105287PRKD225865ChEMBL, NPASS
TAR_EXP_000515ENSG00000010810FYN2534ChEMBL, NPASS
TAR_EXP_000509ENSG00000097007ABL125ChEMBL, NPASS
TAR_EXP_000505ENSG00000198793MTOR2475ChEMBL, NPASS
TAR_EXP_000439ENSG00000068078FGFR32261ChEMBL, NPASS
TAR_EXP_000440ENSG00000066468FGFR22263ChEMBL, NPASS
TAR_EXP_000441ENSG00000160867FGFR42264ChEMBL, NPASS
TAR_EXP_000442ENSG00000000938FGR2268ChEMBL, NPASS
TAR_EXP_000457ENSG00000115687PASK23178ChEMBL, NPASS
TAR_EXP_000461ENSG00000102755FLT12321ChEMBL, NPASS
TAR_EXP_000462ENSG00000122025FLT32322ChEMBL, NPASS
TAR_EXP_000464ENSG00000037280FLT42324ChEMBL, NPASS
TAR_EXP_000095ENSG00000224143EHMT210919ChEMBL, NPASS
TAR_EXP_000078ENSG00000119408NEK610783ChEMBL, NPASS
TAR_EXP_000077ENSG00000145632PLK210769ChEMBL, NPASS
TAR_EXP_000680ENSG00000101336HCK3055ChEMBL, NPASS
TAR_EXP_000067BUB1B-PAK6106821730ChEMBL
TAR_EXP_000054ENSG00000153208MERTK10461ChEMBL, NPASS
TAR_EXP_000042ENSG00000130669PAK410298ChEMBL, NPASS
TAR_EXP_000038ENSG00000136807CDK91025ChEMBL, NPASS
TAR_EXP_000489ENSG00000035664DAPK223604ChEMBL, NPASS
TAR_EXP_000490ENSG00000206203TSSK223617ChEMBL, NPASS
TAR_EXP_000495ENSG00000104205SGK323678ChEMBL, NPASS
TAR_EXP_000498ENSG00000171094ALK238ChEMBL, NPASS
TAR_EXP_000499ENSG00000108839ALOX12239NPASS
TAR_EXP_000502ENSG00000111816FRK2444ChEMBL, NPASS
TAR_EXP_000503ENSG00000161905ALOX15246NPASS
TAR_EXP_000504ENSG00000179593ALOX15B247ChEMBL, NPASS
TAR_EXP_000061ENSG00000134538SLCO1B110599ChEMBL, NPASS
TAR_EXP_001885ENSG00000178999AURKB9212ChEMBL, NPASS
TAR_EXP_001900ENSG00000123595RAB9A9367NPASS
TAR_EXP_001889ENSG00000162889MAPKAPK29261ChEMBL, NPASS
TAR_EXP_001244ENSG00000108984MAP2K65608ChEMBL, NPASS
TAR_EXP_001240ENSG00000169032MAP2K15604ChEMBL, NPASS
TAR_EXP_001239ENSG00000156711MAPK135603ChEMBL, NPASS
TAR_EXP_001238ENSG00000109339MAPK105602ChEMBL, NPASS
TAR_EXP_001237ENSG00000050748MAPK95601ChEMBL, NPASS
TAR_EXP_001236ENSG00000185386MAPK115600ChEMBL, NPASS
TAR_EXP_001245ENSG00000076984MAP2K75609ChEMBL, NPASS
TAR_EXP_001235ENSG00000107643MAPK85599ChEMBL, NPASS
TAR_EXP_001230ENSG00000100030MAPK15594ChEMBL, NPASS
TAR_EXP_001229ENSG00000185532PRKG15592ChEMBL, NPASS
TAR_EXP_001227ENSG00000067606PRKCZ5590ChEMBL, NPASS
TAR_EXP_001226ENSG00000065675PRKCQ5588ChEMBL, NPASS
TAR_EXP_001223ENSG00000184304PRKD15587ChEMBL, NPASS
TAR_EXP_001220ENSG00000065243PKN25586ChEMBL, NPASS
TAR_EXP_001231ENSG00000102882MAPK35595ChEMBL, NPASS
TAR_EXP_001246ENSG00000183943PRKX5613ChEMBL, NPASS
TAR_EXP_001272ENSG00000137843PAK656924NPASS
TAR_EXP_001283ENSG00000183049CAMK1D57118ChEMBL, NPASS
TAR_EXP_001379ENSG00000047936ROS16098ChEMBL, NPASS
TAR_EXP_001375ENSG00000067900ROCK16093ChEMBL, NPASS
TAR_EXP_001366ENSG00000117152RGS45999ChEMBL, NPASS
TAR_EXP_001887ENSG00000100784RPS6KA59252ChEMBL, NPASS
TAR_EXP_001365ENSG00000129473BCL2L2599BindingDB
TAR_EXP_001364ENSG00000171552BCL2L1598BindingDB
TAR_EXP_001363ENSG00000165731RET5979ChEMBL, NPASS
TAR_EXP_001343ENSG00000114200BCHE590BindingDB, ChEMBL, NPASS
TAR_EXP_001342ENSG00000132155RAF15894ChEMBL, NPASS
TAR_EXP_001339ENSG00000136238RAC15879BindingDB
TAR_EXP_001337ENSG00000168067MAP4K25871ChEMBL, NPASS
TAR_EXP_001304ENSG00000160551TAOK157551ChEMBL, NPASS
TAR_EXP_001303ENSG00000101213PTK65753ChEMBL, NPASS
TAR_EXP_001301ENSG00000169398PTK25747ChEMBL, NPASS
TAR_EXP_001286ENSG00000101349PAK557144ChEMBL, NPASS
TAR_EXP_001216ENSG00000163558PRKCI5584ChEMBL, NPASS
TAR_EXP_001429ENSG00000281877RPS6KA16195ChEMBL, NPASS
TAR_EXP_001215ENSG00000027075PRKCH5583ChEMBL, NPASS
TAR_EXP_001213ENSG00000171132PRKCE5581BindingDB, ChEMBL, NPASS
TAR_EXP_001078ENSG00000113721PDGFRB5159ChEMBL, NPASS
TAR_EXP_001074ENSG00000134853PDGFRA5156ChEMBL, NPASS
TAR_EXP_001058ENSG00000106617PRKAG251422ChEMBL
TAR_EXP_001049ENSG00000135090TAOK351347ChEMBL, NPASS
TAR_EXP_001037ENSG00000198001IRAK451135ChEMBL, NPASS
TAR_EXP_001023ENSG00000077264PAK35063ChEMBL, NPASS
TAR_EXP_001087ENSG00000140992PDPK15170ChEMBL, NPASS
TAR_EXP_001022ENSG00000180370PAK25062ChEMBL, NPASS
TAR_EXP_000994ENSG00000162733DDR24921ChEMBL, NPASS
TAR_EXP_000993ENSG00000148053NTRK24915ChEMBL, NPASS
TAR_EXP_000968ENSG00000109320NFKB14790ChEMBL, NPASS
TAR_EXP_000983ENSG00000141458NPC14864NPASS
TAR_EXP_000985ENSG00000196296ATP2A1487BindingDB, ChEMBL, NPASS
TAR_EXP_000992ENSG00000198400NTRK14914ChEMBL, NPASS
TAR_EXP_001016ENSG00000141503MINK150488ChEMBL, NPASS
TAR_EXP_001088ENSG00000087095NLK51701ChEMBL, NPASS
TAR_EXP_001113ENSG00000156873PHKG25261ChEMBL, NPASS
TAR_EXP_001119ENSG00000137193PIM15292ChEMBL, NPASS
TAR_EXP_001212ENSG00000163932PRKCD5580ChEMBL, NPASS
TAR_EXP_001211ENSG00000167601AXL558ChEMBL, NPASS
TAR_EXP_001209ENSG00000166501PRKCB5579ChEMBL, NPASS
TAR_EXP_001207ENSG00000154229PRKCA5578ChEMBL, NPASS
TAR_EXP_001206ENSG00000042088TDP155775ChEMBL, NPASS
TAR_EXP_001203ENSG00000181929PRKAG15571ChEMBL
TAR_EXP_001198ENSG00000288516PRKACA5566ChEMBL, NPASS
TAR_EXP_001197ENSG00000131791PRKAB25565ChEMBL
TAR_EXP_001196ENSG00000111725PRKAB15564ChEMBL
TAR_EXP_001195ENSG00000162409PRKAA25563ChEMBL
TAR_EXP_001194ENSG00000132356PRKAA15562ChEMBL, NPASS
TAR_EXP_001171ENSG00000132170PPARG5468BindingDB, ChEMBL, NPASS
TAR_EXP_001144ENSG00000169118CSNK1G153944ChEMBL, NPASS
TAR_EXP_001140ENSG00000115592PRKAG353632ChEMBL, NPASS
TAR_EXP_001139ENSG00000166851PLK15347ChEMBL, NPASS
TAR_EXP_001214ENSG00000126583PRKCG5582ChEMBL, NPASS
TAR_EXP_001430ENSG00000071242RPS6KA26196ChEMBL, NPASS
TAR_EXP_001861ENSG00000291428BRSK29024ChEMBL, NPASS
TAR_EXP_001916ENSG00000198752CDC42BPB9578ChEMBL, NPASS
TAR_EXP_001930ENSG00000170312CDK1983ChEMBL
TAR_EXP_001431ENSG00000177189RPS6KA36197ChEMBL, NPASS
TAR_EXP_001432ENSG00000108443RPS6KB16198ChEMBL, NPASS
TAR_EXP_001925ENSG00000083290ULK29706ChEMBL, NPASS
TAR_EXP_001931ENSG00000165304MELK9833ChEMBL, NPASS
TAR_EXP_001467ENSG00000188130MAPK126300ChEMBL, NPASS
TAR_EXP_001468ENSG00000204842ATXN26311ChEMBL, NPASS
TAR_EXP_001911ENSG00000134318ROCK29475ChEMBL, NPASS
TAR_EXP_001896ENSG00000149930TAOK29344ChEMBL, NPASS
TAR_EXP_001891ENSG00000164543STK17A9263ChEMBL, NPASS
TAR_EXP_001934ENSG00000074590NUAK19891ChEMBL, NPASS
TAR_EXP_001943ENSG00000070831CDC42998BindingDB