IMPPAT Phytochemical information: 
Thiamine

Thiamine
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
Thiamine supplementation in type 2 diabetesOral thiamine (Vitamin B1) supplementation in subjects with type 2 diabetes mellitus: a randomised, double-blind, placebo-controlled crossover trial assessing biophysical markers of endothelial function, oxidant stress, insulin sensitivity and vascular inflammationISRCTN30703970
Optimum Thiamine Intervention for Treatment and Prevention of Wernicke-Korsakoff Syndrome (WKS): A Randomised Controlled Trial.Optimum Thiamine Intervention for Treatment and Prevention of Wernicke-Korsakoff Syndrome (WKS): A Randomised Controlled Trial.ACTRN12614000327684
Role of Vitamin C hydrocortisone and thiamine in critically sick patients (sepsis and septic shock)Combination of Vitamin C, Hydrocortisone And Thiamine For The Treatment Of sepsis And Septic ShockCTRI/2018/08/015193
Thiamine ( Intravenous Vitamin B1) induced post–operative analgesia in maxillofacial surgery.Role of thiamine in the management of post–operative analgesia in maxillofacial surgery.IRCT201403061674N11
Thiamine to improve stem cell function in patients undergoing bypass surgery: a randomised controlled trialA randomised trial comparing high-dose thiamine to placebo in patients undergoing coronary artery bypass surgery with proliferation of resident cardiac progenitor cells as measured by bromodeoxyuridine (BrdU) assay as primary outcomeACTRN12614000755639
Use of Thiamine supplementation versus placebo on the cardiac function in chronic heart failure patients referred to the cardiology clinic of Imam Khomeini HospitalUse of Thiamine supplementation versus placebo on the cardiac function in chronic heart failure patientsIRCT201311019768N2
Thiamine effect on aerobic and anaerobic powerThiamine effect on aerobic and anaerobic powerIRCT2014103014611N3
Vitamin C, Steroids, and Thiamine, and Cerebral Autoregulation and Functional Outcome in Septic ShockEffect of Combined Vitamin C, Stress-dose Steroids, and Thiamine on Cerebral Autoregulation and Functional Outcomes of Patients with Septic ShockNCT03649633
"How Weekly Vitamin Treatment Affects Thinking in Kidney Patients on Dialysis"""Weekly intravenous thiamine supplementation in chronic kidney disease and Maintenance Haemo Dialysis and effect on cognition: a randomized control study. - NILCTRI/2024/07/070810
Effectiveness of thiamine in treatment of depressionComparison the therapeutic effects of thiamine plus fluoxetine and fluoxetine alone in the patients with major depressive disorderIRCT2013070913929N1
Preoperative parenteral thiamine supplementation in patients undergoing heart surgeryPreoperative parenteral thiamine supplementation in patients undergoing heart surgery – a pilot studyEUCTR2011-004080-70-AT
A clinical trial to study the effect of the addition of thiamine to Standard Care for treating Pulmonary Arterial Hypertension in InfantsNon-Cardiac Pulmonary Arterial Hypertension in Infants Presenting with Respiratory Distress:Assessing the Efficacy of Thiamine Supplementation in a Clinical Setting - NILCTRI/2024/09/073757
Pharmacokinetics of Thiamine in Breastfeeding Mothers and InfantsPharmacokinetics of Thiamine in Breastfeeding Mothers and InfantsNCT01864057
Prevention of Renal Complications of Diabetes With ThiamineNCT01725412
Thiamine Against Chronic Rheumatoid Arthritis FatigueThiamine against chronic rheumatoid arthritis fatigueCTIS2022-500922-13-00
Effect of Thiamine on Oxygen Utilization (VO2) in Critical IllnessThe Effect of Thiamine on VO2 Levels in Critically Ill PatientsNCT01462279
Study on Vitamin C , Thiamine and Hydrocortisone in Septic shock patientsA comparative study on combination therapy of Hydrocortisone, Vitamin C and Thiamine to Hydrocortisone alone in Septic shock patients - NILCTRI/2024/07/070812
Riboflavin and thiamine dietary nutrition supplementation or reduction of anxiety, stress condition and improvement of sleep quality: A randomized double-blind, placebo-controlled trialAssociation between thiamine (vitamin B1) and riboflavin (vitamin B2) nutrition intervention on anxiety, stress and sleep qualityChiCTR2500096497
Hydrocortisone, Vitamin C, and Thiamine for the treatment of septic shockHydrocortisone, Vitamin C, and Thiamine for the Treatment of Sepsis and Septic Shock(ThyVic study)ChiCTR1800018138
Pharmacokinetics of Oral ThiaminePharmacokinetics of High Dose Oral ThiamineNCT01433952
A clinical study done to assess the effects of Vitamin B1 - Vitamin C adjunct therapy in patients with (external forces) traumatic insult to brain.Thiamine - Ascorbic acid adjuvant therapy in Traumatic Brain Injury – A randomized, controlled, parallel-group study - TABCTRI/2019/09/021460
Measurement and evaluation of thiamine concentrations in the blood of Australians who have a history of Diagnostic and Statistical Manual Fourth Edition(DSM IV) alcohol dependence or abuse, after 20 years of supplementing flour with thiamine.Among Australians who have Diagnostic and Statistical Manual Fourth Edition(DSM IV) alcohol dependence or alcohol abuse, has thiamine supplementation of flour resulted in higher median serum thiamine concentrations than the normal population median reference range thus achieving the planned outcome of reducing the risk of Wernicke-Korsakoff syndrome in Australians.ACTRN12610000661077
Steroids, Thiamine and Ascorbic Acid in Septic ShockSteroids, Thiamine and Ascorbic Acid Supplementation in Septic Shock (STASIS): A Prospective Crossover Randomized Controlled StudyNCT04134403
Thiamine Supplementation in Heart Failure Patients Receiving Full Medical TherapyThiamine Supplementation in Heart Failure Patients Receiving Full Medical TherapyNCT01115504
The Effect of Thiamine vs. Placebo on VO2 in Critical IllnessThe Effect of Thiamine vs. Placebo on VO2 in Critical IllnessNCT01985685
Trial of Thiamine Supplementation in CambodiaImproving Estimates of the Global Burden of Thiamine Deficiency Disorders and Approaches to Their Control: Trial of Thiamine Supplementation in CambodiaNCT03616288
Dose-dependent Kinetics of Thiamin in Healthy Volunteers with and Without Functional OCT1 Hepatic TransportersCross-over Randomized Study to Determine Dose-dependent Kinetics of Thiamin in Healthy Volunteers with and Without Functional OCT1 Hepatic TransportersNCT06122701
Effectiveness of Vitamin B1 (Thiamine) Supplementation in Infants with Pulmonary Arterial HypertensionNon-Cardiac Pulmonary Arterial Hypertension in Infants Presenting with Respiratory Distress: Assessing the Efficacy of Thiamine Supplementation in a Clinical Setting - NILCTRI/2024/09/073873
Evaluation of the effectiveness of TAC cocktail in critically ill patients with Covid 19 induced pneumoniaEvaluation of the effectiveness of thiamine-ascorbic acid-methylprednisolone (TAM) cocktail in the treatment of critically ill patients with coronavirus pneumonia (Covid-19) in a clinical trial studyIRCT20200415047080N2
To compare the results of two treatment protocol (standard treatment plus vitamin c, thiamine and hydrocortisone versus standard treatment plus hydrocortisone) used in surgical patients with septic shock (a/k/a infection in the body presenting with low blood pressure).Metabolic resuscitation using early administration of ascorbic acid, thiamine and hydrocortisone in perioperative management of surgical patients with septic shock: A Randomized Controlled trialCTRI/2021/11/038268
Vitamin C, Hydrocortisone and Thiamine in Patients With Septic ShockVitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock: a Randomized Clinical Study (VITAMIN TRIAL)NCT05192213
The effectiveness of infusion of ascorbic acid and thiamine on the clinical implications of severe sepsis patients admitted to ICUThe effectiveness and non effectiveness of infusion of high-dose ascorbic acid and thiamine as an auxiliary treatment on the clinical implications of severe sepsis patients admitted to ICUIRCT20130812014333N78
The Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock TrialThe VitamIn C, HydrocorTisone and ThiAMINe in Patients With Septic Shock Trial (VITAMINS Trial) - A Prospective, Feasibility, Pilot, Multi-centre, Randomised, Open-label Controlled TrialNCT03333278
Trial of the Combined Use of Thiamine and Biotin in Patients With Huntington's DiseaseMulticentric Trial on the Use of Combined Therapy of Thiamine and Biotine in Patients With Huntington´s DiseaseNCT04478734
ROLE OF VITAMIN C AND THIAMINE IN SEPSIS INDUCED REFRACTORY HYPOTENSIONEVALUATION OF THE EFFECTS OF VITAMIN-C AND THIAMINE ON REFRACTORY HYPOTENSION IN PATIENTS WITH SEPSIS:A RANDOMIZED CONTROL STUDYCTRI/2021/02/031043
Benefits of vitamin thiamine, vitamin C,vitamin B12 in children with severe infection - RCTRandomised control study - To study effect of metabolic resuscitation with thiamine & vitamin C, B12 in pediatric severe sepsisCTRI/2020/11/028825
The Effect of Vitamin C, Thiamine and Hydrocortisone on Clinical Course and Outcome in Patients With Severe Sepsis and Septic ShockA Randomized, Double Blind, Placebo-Controlled Study to Investigate the Effects of Vitamin C, Hydrocortisone and Thiamine on the Outcome of Patients With Severe Sepsis and Septic ShockNCT03335124
Thiamine Supplementation in High Risk Cardiac Surgery PatientsThiamine Supplementation in High Risk Cardiac Surgery PatientsNCT03306732
Evaluation of thiamine effect on heart failureEvaluation of thiamine effect on early outcome in patients with low systolic ejection fraction after cardiac surgeryIRCT201702152622N3
High Dose Intravenous Thiamine for the Prevention of Delirium in Allogeneic Hematopoietic Stem Cell TransplantationRandomized Placebo Controlled Trial of High Dose Intravenous Thiamine for the Prevention of Delirium in Allogeneic Hematopoietic Stem Cell TransplantationNCT03263442
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Sepsis and Septic ShockHydrocortisone, Vitamin C, and Thiamine for the Treatment of Sepsis and Septic Shock: A Prospective StudyNCT03258684
Treatment of alcohol dependent patients at-risk for subclinical Wernicke-Korsakoff syndromeTreatment of alcohol dependent patients at-risk for subclinical Wernicke-Korsakoff syndrome: effect of thiamine dosage on neurological and cognitive symptomsACTRN12617001182381
Steroid, Thiamine and Ascorbic Acid for Comatose Out-of-hospital Cardiac Arrest SurvivorsSteroid, Thiamine and Ascorbic Acid During Post-Resuscitation Period for Comatose Out-of-hospital Cardiac Arrest Survivors (STAR) Trial: Multi-center, Randomized, Single-blinded, Controlled Pilot StudyNCT04921189
Open-label study on safety and pharmacokinetics of [11C]thiamine in normal subjectsOpen-label study on safety and pharmacokinetics of [11C]thiamine in normal subjects - PET pharmacokinetics of [11C]thiamineJPRN-UMIN000030940
Thiamine as an Adjunctive Therapy in Cardiac SurgeryThiamine as an Adjunctive Therapy in Cardiac SurgeryNCT02322892
Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in Sepsis.Outcomes of Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in the Early Treatment of Sepsis.NCT03422159
Thiamine, Vitamin C and Hydrocortisone in the Treatment of Septic ShockA Single Center, Investigator Blinded, Randomized Placebo Control, 24 Month, Parallel Group, Superiority Study to Compare the Efficacy of Thiamine, Vitamin C and Hydrocortisone in the Treatment of Septic Shock.NCT03540628
Thiamine deficiency in patients admitted to intensive care with sepsis and septic shockThiamine deficiency in patients admitted to intensive caRe with sEpsis and Septic Shock (TRESS): A Prospective Epidemiological Pilot StudyACTRN12618001165279
The Effect of SLC19A3 Inhibition on the Pharmacokinetics of ThiamineThe Effect of SLC19A3 Inhibition on the Pharmacokinetics of ThiamineNCT03746106
A clinical trial to understand the effect of Vitamin C, Thiamine and hydrocortisone combination in patients with severe infectionsA prospective, open label, randomized controlled trial to evaluate the effect of intravenous vitamin C, Thiamine and Hydrocortisone treatment on all cause mortality among patients with severe sepsis and septic shock. - ViCTORCTRI/2018/07/014787
Comparative study of effectiveness of intravenous high dose of vitamin C and vitamin B1 in patients with severe infection.To compare efficacy of high dose Vitamin C infusion and Thiamine (vitamin B1) infusion in patients of sepsis. - NILCTRI/2024/03/063852
Thiamine As An Adjuvant Therapy For Hyperlactatemia In Septic Shock PatientsThiamine As An Adjuvant Therapy For Hyperlactatemia In Septic Shock Patients: A Prospective Randomized StudyNCT03649009
Thiamin Against Robust IBD FatigueThiamin Against Robust IBD FatigueNCT03634735
Thiamin Deficiency in Obese Thai ChildrenThiamin Deficiency in Obese Thai ChildrenNCT02464865
Vitamin C, Hydrocortisone and Thiamine for Septic ShockA Randomized, Double Blind, Placebo-Controlled Trial to Investigate the Effect of Vitamin C, Hydrocortisone and Thiamine on the Outcome of Patients with Septic ShockNCT03592693
Vitamin C, Thiamine, and Steroids in SepsisA Multi-center, Randomized, Placebo-controlled, Double-blind, Adaptive Clinical Trial of Vitamin C, Thiamine and Steroids as Combination Therapy in Patients With Sepsis.NCT03509350
The protective effect of Thiamine (vitamin B1) for Bortezomib induced peripheral neuropathy in multiple myelomaThe protective effect of Thiamine (vitamin B1) for Bortezomib induced peripheral neuropathy in multiple myelomaIRCT20190116042379N1
Thiamine Supplement in Patients With Severe HyperthyroidismEfficacy of Thiamine Supplement for Improve Cardiovascular Function in Patients With Severe HyperthyroidismNCT02767245
Effect of thiamine on vasopressor requirement in patients with septic shock : A randomized control trialEffect of thiamine on vasopressor requirement in patients with septic shockTCTR20180310001
Thiamine Supplementation in Patients With Septic ShockThiamine Supplementation in Patients With Septic Shock: A Randomized, Double Blind, Placebo Controlled TrialNCT03122678
Vitamin C & Thiamine in SepsisVitamins B1 and C to Improve Outcomes in Patients With Severe SepsisNCT03592277
Effect of Vitamin C, thiamine and hydrocortisone on mortality in septic shock, a randomized placebo-controlled trialEffect of Vitamin C, thiamine and hydrocortisone on mortality in septic shock, a randomized placebo-controlled trialTCTR20180302002
The effect of intravenous thiamine supplementation on AKI outcomes in sepsis patients: A randomized controlled trialThe effect of intravenous thiamine supplementation on AKI outcomes in sepsis patients: A randomized controlled trialTCTR20250526004
Investigating the effect of thiamine, magnesium and vitamin D in the treatment of type 2 diabetic neuropathyThe effect of co-supplementation magnesium, thiamine and vitamin D on glycemic status and severity of neuropathy symptoms in patients with neuropathic type 2 diabetesIRCT20191105045340N6
Does Thiamine Help Vomiting and Nausea in Pregnancy?Comparison Between the Treatment of Thiamine and Promethazine for Improving Vomiting and Nausea in PregnancyNCT00861523
D4T or Abacavir Plus Vitamin Enhancement in HIV-Infected Patients (DAVE)Randomized, Open-Label Study of Continued Stavudine Versus Abacavir Substitution With or Without Riboflavin and Thiamine Supplementation in HIV-Infected Patients Who Have Elevated Venous Lactic Acid While on Stavudine-Based Therapy (DAVE)NCT00143702
Effect of Thiamin Supplementation on Thiamin Status in Children With Heart Disease Receiving Diuretic DrugsEffect of Thiamin Supplementation on Thiamin Status in Children With Heart Disease Receiving Diuretic Drugs: Randomized Controlled TrialNCT03989700
The effect of thiamine supplementation in the treatment of gestational diabetesThe effect of thiamine supplementation on biomarkers of inflammation, oxidative stress and its related gene expression in patients with gestational diabetesIRCT20170513033941N58
The effectiveness of vitamin C and thiamine administration method in the improvement and prognosis of shock patients 1 month to 15 yearsInvestigating the vitamin C and thiamine administration method with the usual method in the improvement and prognosis of shock patients 1 month to 15 yearsIRCT20200825048515N61
Vitamin C, Thiamine and Hydrocortisone for the Treatment of Septic ShockInitiation of Vitamin C, Thiamine and Hydrocortisone Therapy for Septic Shock in Adults: A Randomized Clinical TrialNCT03872011
Evaluation of the effect of Thiamine in the prevention of post-thrombotic syndrome in patients with deep vein thrombosis of the lower extremitiesEvaluation of the effect of Thiamine in the prevention of post-thrombotic syndrome in patients with deep vein thrombosis of the lower extremitiesIRCT20221106056416N1
Vitamin B1 against chronic fatigue in inflammatory bowel diseaseThiamin against robust IBD fatigue- The effect of oral thiamin supplement in 4 weeks to patients with inflammatory bowel disease (IBD) in remission and chronic fatigue.A randomised placebo controlled crossover study - TARIFEUCTR2018-002324-17-DK
Steroids Thiamine and Vitamin C in Septic ShockHydrocortisone, Vitamin C and Thiamine for the Treatment of Severe Sepsis and Septic Shock - STACSSCTRI/2018/04/013384
Evaluating the effect of thiamine on deliriumEvaluating the preventive effect of vitamin B1 on Delirium in critically ill patientsIRCT20190224042815N1
The effect of hydrocortisone, vitamin C, and thiamine for treatment of septic shockThe effect of hydrocortisone , vitamin C, and thiamine for treatment of patients with septic shock addmited to intensive care unit of Ayatollah Mousavi hospital in Zanjan , in 2017-18IRCT20150825023760N7
Vitamin C, Vitamin B1 and Steroid in SepsisEffects of Vitamin C, Thiamine and Hydrocortisone in Septic Shock: a Randomized, Controlled TrialNCT04039815
Trial on the use of thiamine and biotin in patients with Huntington's disease.MULTI-TECHNICAL TEST ON THE USE OF COMBINED THERAPY OF THEMIN AND BIOTINE IN PATIENTS WITH HUNTINGTON'S DISEASE - HuntiamEUCTR2019-004360-22-ES
Ascorbic Acid and Thiamine Effect in Septic ShockCombination Therapy of Vitamin C and Thiamine for Septic Shock: Multi-center, Double-blinded, Randomized, Controlled StudyNCT03756220
Thiamine As Adjunctive Therapy for Diabetic KetoacidosisThiamine As Adjunctive Therapy for Diabetic KetoacidosisNCT03717896
Influence of vitamin B1 suplementation in oxidative stress, energetic metabolism and mortality among patients with septic shockInfluence of thiamine suplementation in oxidative stress, energetic metabolism and mortality among patients with septic shockRBR-9m6bny
The effect of thiamine on inflammation, oxidative stress and cardiac function in patients with chronic heart failure.The effect of thiamine on inflammation, oxidative stress and cardiac function in patients with chronic heart failure.ChiCTR1800018226
Thiamine as a Metabolic Resuscitator in Septic ShockThiamine as a Metabolic Resuscitator in Septic ShockNCT01070810
Assessment of the thiamine effect on post-operative delirium occurrence in patients undergoing hip surgery in intensive care unitAssessment of the thiamine effect on post-operative delirium occurrence in patients undergoing hip surgery in intensive care unitIRCT20230222057489N1
To compare the effectiveness of Thiamine in combination with Vitamin C and itâ??s combination with Glutamine on survival outcome in critically ill patients admitted in ICUTo compare the effectiveness of Thiamine in combination with Vitamin C and its combination with Glutamine on survival outcome in critically ill patients admitted in ICU.CTRI/2023/03/050828
A 2x2 factorial randomized controlled trial. Colchicine will be compared to placebo. Thiamine will becompared to no thiamine (control) in a prospective randomized open-label blinded endpoint(PROBE) design.COLchicine and Thiamine in Heart Failure due to Ischemic Heart Disease (COLT-HF)CTRI/2023/05/052711
Co-administration of Thiamine Pyrophosphate and Metformin in Type 2 DiabetesPirofosfato de Tiamina Como Coadyuvante de la Metformina en el Tratamiento de Pacientes Con Diabetes Mellitus Tipo 2NCT04053621
The effect of Hydrocortisone,Vitamin C and Thiamine in treatment of patients with severe Sepsis/Septic shockThe effect of Hydrocortisone,Vitamin C and Thiamine in treatment of patients with severe Sepsis/Septic shock in ICUIRCT20220219054058N1
Thiamine in Aluminium Phosphide PoisoningThe Effect of Thiamine in Aluminium Phosphide Poisoning PatientsIRCT20211221053473N1
Thiamine level in out of hospital cardiac arrest patientsThiamine deficiency among cardiac arrest patients.TCTR20210810008
Effect of thiamine and magnesium sulfate in treatment of diabetesInvestigating the effect of magnesium and thiamine combination to improve hyperglycemia and insulin resistance in type 2 diabetic patientsIRCT20151028024756N4
The Effect of Vitamin C and Thiamine in SepsisThe Effect of Vitamin C and Thiamine in Sepsis: An Open Label Randomised Controlled TrialCTRI/2021/07/035107
PBC Induced Fatigue Treated With ThiaminePBC Induced Fatigue Treated With Thiamine (PIFT) - The Effect of Oral Thiamine Supplement in 4 Weeks to Patients With Primary Biliary Cholangitis (PBC) and Chronic Fatigue. A Randomised Placebo Controlled Crossover StudyNCT04893993
A multicentre, randomized, controlled trial for thiamine and folate in the treatment of cognitive impairment in maintenance hemodialysis patientsA multicentre, randomized, controlled trial for thiamine and folate in the treatment of cognitive impairment in maintenance hemodialysis patientsChiCTR2000029297
Thiamine deficiency among pregnant and lactating womenGene polymorphism, prevalence, risk factors and dose optimization studies of thiamine in thiamine deficiency states during pregnant and lactating womenCTRI/2022/07/044217
The effectiveness of thiamine on cognitive symptoms after electroconvulsive therapy in patients with mood disordersEffect of thiamine on cognitive symptom in the patients with mood disorder in the depression phase under electroconvulsive therapy (clinical trial- double blind)IRCT20190525043700N3
The Thiamine Administration After Cardiac Surgery TrialThe Thiamine Administration After Cardiac Surgery TrialNCT04641104
Supplemental Thiamine in Septic Shock: A Before-after StudyImpact of Thiamine Supplementation on Clinical Outcomes of Patients With Septic Shock: a Retrospective Before-after StudyNCT05840718
Efficacy of Thiamine in Amnisia due to Electro Convulsive TherapyEffectiveness of Thiamine on Cognitive Performance of Paitients Under Electro-Convulsive Therapy: A Randomized Double Blind Clinical Trial.IRCT20191218045795N4
Outcomes of Septic Shock Patients Treated With a Metabolic Resuscitation Bundle Consisting of Intravenous Hydrocortisone, Ascorbic Acid and Thiamine.Outcomes of Septic Shock Patients Treated With a Metabolic Resuscitation Bundle Consisting of Intravenous Hydrocortisone, Ascorbic Acid and Thiamine.NCT03913468
Evaluation of Aminobutyric Acid, Glutamic Acid, Calcium, Thiamine, Pyridoxine and Cyanocobalamin as Therapy for VertigoDouble Blind Evaluation of Gamma-aminobutyric Acid Tartarate 100 mg, Glutamic Acid 100 mg, Dibasic Calcium Phosphate 50 mg, Thiamine Nitrate 25 mg, Pyridoxine Chloride 10 mg and Cyanocobalamin 5 mcg Versus Ginger for Vertigo-kinetosisNCT05221892
Thiamine and estimated glomerular filtration rate in type 2 diabetes with chronic kidney disease stage 3: A pragmatic randomized controlled trialThiamine and estimated glomerular filtration rate in type 2 diabetes with chronic kidney disease stage 3: A pragmatic randomized controlled trialTCTR20200215004
Thiamine Administration and Prevalence of Delirium in the Intensive Care Unit: A Before-after StudyThiamine Administration and Prevalence of Delirium in the Intensive Care Unit: A Before-after StudyNCT04214106
Vitamin B1 as treatment for chronic fatigue in patients with primary biliary cholangitisPBC induced fatigue treated with thiamine- The effect of oral thiamine supplement in 4 weeks to patients with primary biliary cholangitis (PBC) and chronic fatigue.A randomised, double-blinded, placebo-controlled, crossover study - PIFTEUCTR2020-004935-26-DK
Role of Vitamin C and Thiamine in patients with sepsis in Indian Population: Single blind, Parallel Group, Randomized controlled trialTo study the effect of Vitamin C and Thiamine in patients with sepsis in Indian Population: Single blind, Parallel Group, Randomized controlled trial - Sepsis, Vitamin C, ThiamineCTRI/2019/05/018992
COLchicine and Thiamine in Heart Failure Due to Ischemic Heart DiseaseCOLchicine and Thiamine in Heart Failure Due to Ischemic Heart DiseaseNCT05873881
THIAMINE SUPPLEMENTATION IN DIABETIC KETOACIDOSISTHIAMINE SUPPLEMENTATION IN THE MANAGEMENT OF DIABETIC KETOACIDOSIS: AN OPEN LABEL RANDOMIZED CONTROLLED TRIALCTRI/2023/05/053199
Experimental regimen of hydrocortisone, vitamin C and thiamine in the treatment of severe sepsis and septic shockExperimental regimen of hydrocortisone, vitamin C and thiamine in the treatment of severe sepsis and septic shockChiCTR1900024864
The effect of Thiamin on Coronary Artery Bypass GraftingThe effect of Thiamin on serum lactate level after Coronary Artery Bypass Surgery in Patients with Mild Systolic DysfunctionIRCT2016051412642N24
Comparison of prevalence and clinical manifestation of thiamine deficiency status in patients with different in etiologyComparison of prevalence and clinical manifestation of thiamine deficiency status in patients with different in etiologyTCTR20211222006
Ascorbic Acid, Corticosteroids, and Thiamine in Sepsis (ACTS) TrialAscorbic Ccid, Hydrocortisone, and Thiamine in Sepsis and Septic Shock - A Randomized, Double-Blind, Placebo-Controlled TrialNCT03389555
Therapy With Hydrocortisone, Ascorbic Acid, Thamine in Patients With SepsisThe Effect of Hydrocortisone-Ascorbic Acid and Thiamine Therapy on the Outcome of Patients With Sepsis: A Prospective Randomized Double-Blinded Controlled TrialNCT04160676
Oral Thiamine for the Treatment of Painful Diabetic Peripheral NeuropathyA Randomized Double Blinded Pilot Study of Oral Thiamine in the Symptomatic Treatment of Painful Diabetic Peripheral NeuropathyNCT00279266
Thiamine Supplementation in Heart Failure: a Pilot Randomized Controlled Crossover TrialThiamine Supplementation in Heart Failure: a Pilot Randomized Controlled Crossover TrialNCT03228030
A Trial of Thiamin Supplementation in Patients With Heart FailureA Randomized Controlled Trial of the Effect of Thiamin Supplementation on Heart Function in Ambulatory Patients With Heart FailureNCT00959075
Thiamine and Acute Decompensated Heart Failure: Pilot StudyTargeting Myocardial Energy Metabolism for the Treatment of Acute Heart Failure: The Effect of Thiamine on Biochemical, Electrocardiographic and Respiratory Parameters in Hospitalized Patients.NCT00680706
Thiamine Supplementation to Improve Cardiac Function in Patients With Congestive Heart FailureThiamine Supplementation to Improve Cardiac Function in Patients With Congestive Heart Failure on Long-term Treatment With Diuretic DrugsNCT00770107
Effect of high dose vitamin B1 on early stage kidney disease in type 2 diabetesA randomised, double-blind, placebo-controlled study to assess if high dose thiamine therapy of type diabetic patients with microalbuminuria decreases the urinary excretion of albuminAcronym: THIAMACTRI/2008/091/000112
Beriberi (Vitamin B1 deficiency)- Burden and Intervention study in High burden districts of North East IndiaA study on Prevalence & factors associated with Thiamine deficiency among Pregnant and Lactating mothers living in Assam and Tripura and Assessing the Impact of Health and Nutritional Education as a Sustainable model of Intervention - NILCTRI/2023/07/055337
Effect of test drugs (Hydrocortisone, Ascorbic acid, and Thiamine) in patients with septic shock.Metabolic Resuscitation in Pediatric Septic Shock Using HAT (Hydrocortisone, Ascorbic acid and Thiamine) Therapy an Open Label Randomized Controlled TrialCTRI/2023/11/059609
STUDYING THE ADVANTAGE OF ADDITIONAL USE OF VITAMIN SUPPLEMENTS (VITAMIN B1 AND VITAMIN C) IN CHILDREN WITH SEVERE DENGUE GETTING ADMITTED IN PEDIATRIC INTENSIVE CARE UNIT.CLINICAL EFFECTIVENESS OF ASCORBIC ACID AND THIAMINE AS ADJUNCTIVE THERAPY IN CHILDREN WITH SEVERE DENGUE REQUIRING PICU (PEDIATRIC INTENSIVE CARE UNIT) CARE- OPEN LABELLED RANDOMISED CONTROLLED TRIAL.CTRI/2019/09/021244
Multicentric trial on the use of combined therapy of Thiamine and biotine in patients with Huntington´s disease.Multicentric trial on the use of combined therapy of Thiamine and biotine in patients with Huntington´s disease. - HUNTIAMCTIS2023-508637-14-00
Efficacy of thiamine in treatment of post-cardiac arrest patients: a randomized controlled pilot studyEfficacy of thiamine in treatment of post-cardiac arrest patients: a randomized controlled pilot studyTCTR20161226001
Effect of IV Vitamin C, Thiamine, and Steroids on Mortality of Septic ShockEffect of IV Vitamin C, Thiamine, and Steroids on Mortality of Septic ShockNCT03828929
Does thiamin treatment reduce the incidence of adverse effects during treatment of falciparum malaria?Thiamin treatment and Plasmodium falciparum malaria in LaosISRCTN85411059
Effect of vitamin B1on septic shock patiensEffectiveness of initial administration of thiamine in patients with septic shock in patients admitted in the adult intensive care unitIRCT20190602043787N2
Effect of thiamine tablet ( B 1) on general health and treatment success in infertile women with polycystic ovary syndromEffect of thiamine tablet ( B 1) on general health and treatment success in infertile women with polycystic ovary syndromIRCT201510266917N3
To study ,if giving a combination therapy with injection Hydrocortisone, Ascorbic acid and Thiamine can help in decreasing the severity or early recovery of children diagnosed with sepsisAdjunctive Hydrocortisone,Ascorbic Acid And Thiamine (HAT) Therapy With Standard Care In The Outcome Of Pediatric Sepsis - NILCTRI/2023/10/058991
Thiamine Intervention and Coronary Artery Bypass GraftingThiamine Intervention and Cognition in Older Adults Undergoing Coronary Artery Bypass Grafting - a Randomized Clinical Trial.NCT06326996
The Role of Thiamine After Transcatheter Closure in Children With Left-to-Right Shunt Congenital Heart DiseaseThe Role of Thiamine on Left Ventricular Structure and Function After Transcatheter Closure Through the Examination of MMP-9 Dan TIMP-1 in Children With Left-to-Right Shunt Congenital Heart DiseaseNCT06298344
Thiamin Fortified Fish Sauce as a Means of Combating Infantile Beriberi in Rural CambodiaThiamin Fortified Fish Sauce as a Means of Combating Infantile Beriberi in Rural CambodiaNCT02221063
Survey of thiamin efficacy on urine protein level in diabetic patients with kidney involvementSurvey of thiamin efficacy on proteinuria in diabetic nephropathyIRCT201105302858N3
Vitamin C, Thiamine, Cyanocobalamine, Pyridoxine and Hydrocortisone in SepsisDifference in Mortality and Evolution in Septic Patients Treated With Vitamin C, Tiamine, Cyanocobalamine, Pyridoxine and Hydrocortisone Treated at the ICU of General Hospital Zone 11 IMSS Piedras Negras Coahuila.NCT04197115
The effect of vitamin B1 (thiamine) on blood pressure, lipid profile, liver enzymes and fasting blood sugar in the military with metabolic syndromeThe effect of vitamin B1 (thiamine) on blood pressure, lipid profile, liver enzymes and fasting blood sugar in patients with metabolic syndromeIRCT20180201038585N5
Vitamin B1 (thiamine) administration in enterally-fed critically ill patients with hypophosphatemia: A prospective, randomised clinical trialEffect of exogenous vitamin B1 (thiamine) administration on blood lactate concentrations in enterally-fed, critically ill patients with hypophosphatemiaACTRN12619000121167
The chronic effects of thiamin on cardiovascular risk factors in individuals with hyperglycaemiathiamin supplementation in those with hyperglycaemia: impact on blood lipids, microalbuminaemia and endothelial dysfunctionACTRN12611000051943
How much thiamine is enough in malnourished patients receiving total parenteral nutrition?Thiamine levels and duration of replacement in patients receiving total parenteral nutrition (TPN) with moderate to severe risk of refeeding - a prospective randomised controlled trialACTRN12623000589684