IMPPAT Phytochemical information: 
Mannitol

Mannitol
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
Mannitol-Induced Cough Challenge in Healthy Controls and Subjects With Mild Allergic AsthmaMannitol-Induced Cough Challenge in Healthy Controls and Subjects With Mild Allergic AsthmaNCT03620422
The effect of using drug(mannitol) in additional quantities according to weight in patient undergoing open heart surgery."""Efficiency of using mannitol according to weight in patients undergoing cardiopulmonary bypass""."CTRI/2018/05/014115
Effect of Mannitol 20% Versus Hypertonic Saline 7.5% in Brain Metabolism and OxygenationEffect of Isosmotic Doses of Mannitol 20% Versus Hypertonic Saline 7.5% in Brain Metabolism and Oxygenation in Supratentorial CraniotomiesNCT03573999
Comparison of effect of Mannitol and 3% saline on cerebral hemodynamics of head injury patientsA prospective study to compare effect of mannitol and 3% hypertonic saline on cerebral hemodynamics in head injury patients.CTRI/2018/05/013830
Effects of Mannitol on Delayed Graft Function After Cadaveric Renal TransplantationEffects of Mannitol on Delayed Graft Function After Cadaveric Renal TransplantationNCT02705573
Efficacy of Mannitol on the success rate of anesthesia in mandibular posterior teethAneasthetic success of Articaine\Epinephrine with combination of Mannitol in comparison with Articaine\Epinephrine for inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: A randomized controlled clinical trialIRCT20180228038901N1
Comparison of effect of Mannitol andmannitol plus glycerol combination on brain relaxation andsystemic hemodynamics in elective tumorsurgeries- A Randomized Controlled TrialComparison of effect of equiosmolar doses of Mannitol andmannitol plus glycerol combination on brain relaxation andsystemic hemodynamics in elective supratentorial tumorsurgeries- A Randomized Controlled Trial - NILCTRI/2025/05/087889
Effect of Mucolytic in treatment of cystic fibrosisComparison of the nebulized Mannitol with nebulized Hypertonic saline on pulmonary function in patients with cystic fibrosisIRCT20180307038994N1
A randomized phase II study of furosemide or mannitol in cisplatin-based chemotherapy using short hydrationA randomized phase II study of furosemide or mannitol in cisplatin-based chemotherapy using short hydration - A randomized study of furosemide or mannitol in short hydration chemotherapyJPRN-UMIN000031910
The Effect of Deep Inhalation on Mannitol ResponsivenessThe Effect of Deep Inhalation on Mannitol ResponsivenessNCT03505489
Clinical study of mannitol in preventing postoperative nausea and vomiting after posterior scleral reinforcementClinical study of mannitol in preventing postoperative nausea and vomiting after posterior scleral reinforcementChiCTR2500103212
Effect of Mannitol on Propofol LevelPropofol Level At TCI During MannitolNCT06884657
Comparison the effects of mannitol between at the time immediately after anesthesia induction and skin incision on brain relaxation in craniotomyComparison the effects of mannitol between at the time immediately after anesthesia induction and skin incision on brain relaxation in craniotomy, A prospective randomized controlled trialTCTR20250224001
The Effect of Mannitol Volume with Changes in Osmolarity in Traumatic Brain InjuryThe Effect of Mannitol Volume Administration with Changes in Osmolarity in Traumatic Brain Injury: an Observational StudyNCT06846307
The Therapeutic Time Window of Mannitol During Craniotomy for Optimal Brain Relaxation in Patients With Supratentorial TumoursBrain Relaxation Facilitated by Mannitol in Craniotomy: Insight Into the Optimized Operation WindowNCT03444519
Effect of mannitol and hypertonic saline on brain tumorEvaluation of effect of preoperative infusion of mannitol vs hypertonic saline on ICP and inflammatory biomarkers in brain tumor patients undergo craniotomy at Sina hospital,a randomized clinical trialIRCT20161126031091N2
Inhaled mannitol improves sputum clearance in intubated patientsSafety and efficacy of dry powder mannitol inhalation by intubated patients with sputum retentionACTRN12609000145202
Mannitol efficacy in ovarian hyper stimulation syndromeEfficacy Assessment of Mannitol vs Albumin in Management of Ovarian Hyperstimulation Syndrome – A randomized controlled trialIRCT20180305038953N1
Mannitol versus normal saline in brain death donors and recipients of kidney allograft on delayed graft function (MAVERICK)Mannitol versus normal saline in brain death donors and recipients of kidney allograft on delayed graft function (MAVERICK) – A double-blinded, placebo-controlled randomized clinical trialCTIS2024-518817-24-01
Effects of different infusion time length of mannitol on blood potassium and intracranial pressure in craniotomyEffects of different infusion time length of mannitol on blood potassium and intracranial pressure in craniotomyChiCTR1800018584
A prospective, multicenter, randomized controlled clinical study on the improvement of chemotherapy-related constipation by oral administration of mannitol injectionA prospective, multicenter, randomized controlled clinical study on the improvement of chemotherapy-related constipation by oral administration of mannitol injectionChiCTR2500096582
A Dose-Image Optimization Trial Evaluating Mannitol and Voluven as Adjuncts for Indocyanine GreenAdvanced Research on ICG Fluorescence Imaging-Guided Surgery Technique Using Mannitol and Voluven as AdjunctsNCT06768268
Effects of acetaminophen mannitol injection on acute pain and levels of inflammatory mediators in patients undergoing thoracoscopic wedge-shaped lung resectionEffects of acetaminophen mannitol injection on acute pain and levels of inflammatory mediators in patients undergoing thoracoscopic wedge-shaped lung resectionChiCTR2400094327
Mannitol versus mannitol and glycerol combination for brain relaxation during brain aneurysm surgeryCOMBINATION OF 10 PERCENT MANNITOL WITH 10 PERCENT GLYCERINE VERSUS 20 PERCENT MANNITOL FOR INTRAOPERATIVE BRAIN RELAXATION IN PATIENTS WITHACUTE ANEURYSMAL SUBARACHNOID HAEMORRHAGE UNDERGOINGCRANIOTOMY AND CLIPPING OF ANEURYSM - MANGLCTRI/2024/12/077678
Intravenous paracetamol and mannitol injection as an adjunct to epidural labor analgesia with ropivacaine and fentanyl in pregnant womenAnalysis of the efficacy of intravenous acetaminophen as an adjunct to maternal epidural labor analgesiaChiCTR2400092770
How Taking Meloxicam Before a Lidocaine and Epinephrine Injection, Combined with Mannitol, Affects Pain Relief in Dental Nerve Blocks: A StudyEffect Of Premedication With Meloxicam on Anaesthetic Efficacy of A Combination of Mannitol Plus LIdocaine With Epinephrine In Inferior Alveolar Nerve Block: A Randomized Control Trial - NILCTRI/2024/11/076797
A Safety and Efficacy Trial of Inhaled Mannitol in Adult Cystic Fibrosis SubjectsLong Term Administration of Inhaled Mannitol in Cystic Fibrosis - A Safety and Efficacy Trial in Adult Cystic Fibrosis SubjectsNCT02134353
A clinical trial to compare the efficacy and safety of intravenous hypertonic saline versus mannitol in patients of spontaneous intracranial haemorrhageComparison of efficacy and safety profile of intravenous hypertonic saline versus mannitol in patients with spontaneous intracranial haemorrhage - a randomized controlled trial - NILCTRI/2025/05/087854
Coagulation Activation by Hyperosmolar Agents in Intracranial HypertensionEvaluation of Coagulation Activation in Patients With Intracranial Hypertension After Treatment With Mannitol or Hypertonic Saline Solution.NCT03409237
Brain Relaxation With Mannitol and FurosemideComparison of Mannitol Alone Versus Different Doses of Mannitol in Combination With Furosemide on Brain Relaxation in Supratentorial Mass Resection SurgeryNCT02712476
Effects of Equiosmolar Doses of 10% Hypertonic Saline and 20% Mannitol in Patients With Spontaneous Intracerebral Hemorrhage: A Prospective, Multi-center, Randomized Controlled TrialEffects of Equiosmolar Doses of 10% Hypertonic Saline and 20% Mannitol in Patients With Spontaneous Intracerebral Hemorrhage: A Prospective, Multi-center, Randomized Controlled TrialChiCTR-INR-16008186
Evaluation of the Effect of Acetazolamide, Mannitol and N-acetylcysteine on Cisplatin-Induced NephrotoxicityEvaluation of the Effect of Acetazolamide, Mannitol and N-acetylcysteine on Cisplatin-Induced NephrotoxicityNCT02760901
If the drug Mannitol is not given to the kidney donor during the removal of the kidney, does it adversely affect short term function of the kidney in the patient receiving the kidney?Withholding Mannitol in donor nephrectomy- Does it affect short-term allograft function? - -CTRI/2015/11/006371
Mannitol Versus Supportive Care in Ciguatera Fish PoisoningMannitol Versus Supportive Care in Ciguatera Fish Poisoning: A Randomized Control TrialNCT02570971
Performance of 13C Mannitol for in Vivo Measurement of Small Intestinal PermeabilityPerformance of 13C Mannitol for in Vivo Measurement of Small Intestinal PermeabilityNCT02603822
Comparison effects of Mannitol 20% and Hypertonic Saline 5% on Electrolyte Balance during Brain Tumor SurgeryComparison effects of Mannitol 20% and Hypertonic Saline 5% on Electrolyte Balance during Brain Tumor SurgeryIRCT2015060222535N1
The curative effect and security of Neostigmine combined mannitol treatment of Acute Pancreatitis combined with Intra-abdominal Hypertension or Abdominal Compartment Syndrome: A clinical control studyThe curative effect and security of Neostigmine combined mannitol treatment of Acute Pancreatitis combined with Intra-abdominal Hypertension or Abdominal Compartment SyndromeChiCTR-IPR-15006580
Mannitol Cream for Post Herpetic NeuralgiaMannitol Cream in the Treatment of Post-herpeticNeuralgia;a Randomized Placebo-Controlled Crossover Pilot StudyNCT02484170
Effects of mannitol on kidney function after kidney transplantationEffects of mannitol on delayed graft function aftercadaveric renal transplantationEUCTR2014-005391-29-AT
An assessment of the transit times of various liquids and neutraceuticals through the various compartments of the gut using a SmartPill, Registered Trademark.Assessment of the effect of intestinal permeability probes (lactulose and mannitol) and other liquids on digesta residence times in various segments of the gut determined by wireless motility capsule in healthy female subjects.ACTRN12615000596505
Role of Hypertonic Saline Versus Mannitol in the Management of Raised Intracranial Pressure in Patients With ALFRole of Hypertonic Saline Versus Mannitol in the Management of Raised Intracranial Pressure in Patients With ALF: A Randomized Open -Label StudyNCT02460510
Comparison effects of mannitol and hypertonic saline on coagulation in vitro: a randomized, blinded trial.Comparison effects of 20 % mannitol and 3 % hypertonic saline on coagulation in vitro in healthy volunteers: a randomized, blinded trial.ACTRN12615000005550
Randomized phase II feasibility study of mannitol or furosemide hydration in moderate dose of cisplatin-based chemotherapy with short hydration for advanced non-small cell lung cancerRandomized phase II feasibility study of mannitol or furosemide hydration in moderate dose of cisplatin-based chemotherapy with short hydration for advanced non-small cell lung cancer - Randomized phase II feasibility study of mannitol or furosemide hydration in cisplatin-based chemotherapy with short hydration for advanced non-small cell lung cancerJPRN-UMIN000015293
Mannitol Brain Relaxation EffectCan Mannitol Increments Provide More Brain Relaxation in Patients Undergoing Craniotomy for Supratentorial Brain Tumor Removal?NCT02168075
Dextran-based Priming vs. Crystalloid and Mannitol-based Priming Solution in Adult Cardiac SurgeryA Randomized Controlled Trial Comparing Dextran-based Priming (PrimECC), and Standard Crystalloid and Mannitol-based Priming Solution in Adult Cardiac SurgeryNCT02767154
Long Term Administration of Inhaled Mannitol in Cystic Fibrosis – A Safety and Efficacy Trial in Adult Cystic Fibrosis SubjectsLong Term Administration of Inhaled Mannitol in Cystic Fibrosis – A Safety and Efficacy Trial in Adult Cystic Fibrosis SubjectsEUCTR2013-005357-79-CZ
Investigating the effect of Albumin on urine output, using it with lasix and mannitol in ICU patients with oliguriaA clinical trial of comparing the effect of Albumin administration on urine output when using with lasix and mannitol with using lasix and mannitol without Albumin in oliguric patients in ICUIRCT2016013010741N3
Comparative Study Between Hydrocortisone and Mannitol in Treatment of Postdural Puncture HeadacheComparative Study Between Hydrocortisone and Mannitol in Treatment of Postdural Puncture Headache: a Randomized Double-blind StudyNCT02760862
A Comparison of Equivolume, Equimolar Solutions of 3% Hypertonic Saline and20 % Mannitol for intracranial pressure change in patients undergoing elective supratentorial tumor surgery: A Randomized, Blind Clinical Trial.A Comparison of Equivolume, Equimolar Solutions of 3% Hypertonic Saline with dose of 5ml/kg and 20 % Mannitol with dose of 1gr/kg for intracranial pressure change in patients undergoing elective supratentorial tumor surgery: A Randomized, Blind Clinical Trial.ACTRN12616000655448
The application and inflammation effects of hypertonic saline hydroxyethyl starch 40 and mannitol injection in elder patients during intracranial tumour neurosugeryThe application of hypertonic saline hydroxyethyl starch 40 and mannitol injection in elder patients during intracranial tumour neurosugeryChiCTR-IPR-16009005
the effect of a 20% mannitol solution and a 10% hypertonic saline solution on increased intracranial pressure after large hemispheric infarctionthe effect of a 20% mannitol solution and a 10% hypertonic saline solution on increased intracranial pressure after large hemispheric infarctionChiCTR-IPR-17010545
Comparison of two medicines used during surgery to assess heart rate,blood pressure, brain tension and electrolyte abnormality in patients undergoing brain surgeryComparison of equiosmolar concentrations of combination of mannitol and hypertonic saline vs mannitol alone to assess hemodynamic profile, brain relaxation and electrolyte abnormalities in patients undergoing elective supratentorial craniotomy-A Randomised Control TrialCTRI/2017/03/008189
Sensory-Mechanical Responses to Eucapneic Voluntary Hyperventilation and MannitolSensory-Mechanical Responses to Eucapneic Voluntary Hyperventilation and Mannitol in Individuals with Cough Variant Asthma and Chronic CoughNCT03105843
Irrigating Fluid and Blood CoagulationThe Effect of a Mixture of 2.7% Sorbitol-0.54% Mannitol Solution on Blood Coagulation: In-vitro, Observational Healthy-volunteer Study Using Rotational Thromboelastometry (ROTEM®)NCT03105180
Topical Menthol +/- Mannitol for Painful Diabetic Peripheral NeuropathyA Double Blind, Randomized Crossover Study of Efficacy and Safety of Topical Menthol, With and Without Mannitol, in the Treatment of Painful Diabetic Peripheral NeuropathyNCT02728687
Analysis of water and electrolyte balance during osmotherapy in meningitis/encephalitisAssessment of one dose Mannitol influence on hydration and electrolytes concentration in patients with viral meningitisISRCTN48274252
The Effect of Mannitol on the Serum Potassium During CraniotomyThe Effect of Mannitol on Intraoperative Serum Potassium in Patients Undergoing Craniotomy:an Observational StudyNCT03161977
Effect of Mannitol on Optic Nerve Sheath Diameter in Patients Undergoing Robotic ProstatectomyEffect of Mannitol on Optic Nerve Sheath Diameter in Patients Undergoing Robot-assisted Laparoscopic Radical Prostatectomy: a Prospective Observational StudyNCT03214055
Efficacy and safety of oral mannitol solution and polyethylene glycol electrolyte powder for bowel preparation before cold resection of colorectal polyps with diameter < 10mm: a national multicenter randomized controlled trialEfficacy and safety of oral mannitol solution and polyethylene glycol electrolyte powder for bowel preparation before cold resection of colorectal polyps with diameter < 10mm: a national multicenter randomized controlled trialChiCTR2500104100
Effect of mannitol in lowering intra cranial tension during robotic assisted procedures in head down positionEffects of different doses of mannitol on intracranial pressures during robotic assisted procedures in tredelenberg position. A single center randomized control trialCTRI/2018/01/011556
comparison of 2 drugs to manage brain swelling in patients with head injuryA comparative study of 3% Hypertonic saline and 20% mannitol in the treatment of refractory post traumatic intracranial hypertensionCTRI/2016/04/006829
Effect of Mannitol on Recovery Pattern After Orthognathic SurgeryEffect of Mannitol on Recovery Pattern After Orthognathic Surgery, a Prospective Randomized Double Blind Controlled Study.NCT06400355
The effect of acetaminophen mannitol injection on postoperative analgesia and respiratory function recovery in patients with coronary artery bypass graftingThe effect of acetaminophen mannitol injection on postoperative analgesia and respiratory function recovery in patients with coronary artery bypass graftingChiCTR2400090159
Comparison of the effect of mannitol and hypertonic sodium administration to reduce ICP on hemodynamic parametersComparison of the effect of mannitol and hypertonic sodium administration to reduce ICP on hemodynamic parameters under LiDCO monitoring in patients undergoing elective craniotomyIRCT20170805035510N7
Effect of Mannitol on Postreperfusion Syndrome During Living Donor Liver TransplantEffect of Mannitol on Postreperfusion Syndrome During Living Donor Liver Transplant: a Randomized Clinical TrialNCT05277623
Mannitol for acute kidney injury during liver transplantationMannitol for prevention of Acute Kidney Injury during living donor Liver Transplantation: A Randomized Controlled TrialPACTR202203622900599
The effect of preoperative intravenous mannitol injection in reducing acute kidney injury following percutaneous nephrolithotomyThe effect of preoperative intravenous mannitol injection in reducing acute kidney injury following percutaneous nephrolithotomyIRCT20200110046073N1
Comparison of intravenous mannitol and acetaminophen caffeine in postural headache after cesarean sectionComparison of intravenous mannitol and oral acetaminophen caffeine in treatment of post dural puncture headache after cesarean section by spinal anesthesiaIRCT20121006011020N12
The effect of dupilumab on airway twitchiness in severe asthmaA pragmatic proof of concept study to evaluate the effect of dupilumab on mannitol challenge in severe asthma with type 2 inflammationISRCTN70810039
Efficacy of Sodium Thiosulfate and Mannitol in Reducing Ototoxicity in Adult Patients Receiving Cisplatin ChemotherapyA Multicenter Randomized Phase II Clinical Trial of the Efficacy of Sodium Thiosulfate and Mannitol in Reducing Ototoxicity in Adult Patients Receiving Cisplatin ChemotherapyNCT05129748
Effects of mannitol versus hypertonic saline on intraoperative cardiac index in patients undergoing supratentorial brain tumor craniotomyEffects of mannitol versus hypertonic saline on intraoperative cardiac index in patients undergoing supratentorial brain tumor craniotomy: A prospective double-blind randomized clinical trialKCT0007634
Comparative sebum control efficacy of BGM complex (Bakuchiol, Ginkgo, and Mannitol) combined with adapalene 0.1%/benzoyl peroxide 2.5% gel and adapalene 0.1%/benzoyl peroxide 2.5% gel monotherapy in mild to moderate acne vulgaris patientsComparative sebum control efficacy of BGM complex (Bakuchiol, Ginkgo, and Mannitol) combined with adapalene 0.1%/benzoyl peroxide 2.5% gel and adapalene 0.1%/benzoyl peroxide 2.5% gel monotherapy in mild to moderate acne vulgaris patientsTCTR20190614007
to study the effectiveness of mannitol with routine local anesthesia in nerve blocksEfficacy of 0.5M Mannitol as an adjuvant with lidocaine with epinephrine for intraoral nerve blocks â?? A split-mouth studyCTRI/2022/10/046921
Comparing the Effects of Furosemide, Mannitol, and Dopamine on Diuresis in Patients under Cesarean SectionComparing the effects of Furosemide, Mannitol, and Dopamine on Diuresis in Patients with Cesarean Section under Spinal AnesthesiaIRCT20191012045070N1
role of hypertonic saline versus mannitol in reducing cerebral edema in childrenTo study the role of 3% hypertonic saline and mannitol in the reduction of raised intracranial pressure in childrenCTRI/2022/11/047736
The effect of using mannitol serum in Cardiopulmonary Bypass Priming on Laboratory Parameters and Delirium in patients undergoing Coronary Artery Bypass graft surgeryThe effect of using mannitol serum in Cardiopulmonary Bypass Priming on Laboratory Parameters and Delirium in patients undergoing Coronary Artery Bypass graft surgeryIRCT20221129056660N1
Comparative measurements of Intestinal permeability by using urine Lactulose/Mannitol ratio between patient with Functional bloating or bloating predominant FGIDs, Inflammatory bowel disease (IBD) and healthy volunteerComparative measurements of Intestinal permeability by using urine Lactulose/Mannitol ratio between patient with Functional bloating or bloating predominant FGIDs, Inflammatory bowel disease (IBD) and healthy volunteerTCTR20200203001
A Study Comparing Picoprep With Mannitol and Bisacodyl for Colon Cleansing in Preparation for ColonoscopyA Randomized, Controlled, Parallel Group, Assessor-Blinded Study To Compare The Efficacy, Tolerability, And Safety Of Oral Sodium Picosulfate (PicoPrep®) Versus Oral Mannitol and Bisacodyl, For Colon Cleansing In Colonoscopy Preparation Of Adult OutpatientsNCT02386449
Comparison of Hypertonic saline solution and Mannitol to improve brain relaxation during craniotomy in patients with brain tumor: A prospective randomized - controlled trialComparison of Hypertonic saline solution and Mannitol to improve brain relaxation during craniotomy in patients with brain tumor: A prospective randomized - controlled trialTCTR20211027001
Measurement of Optic nerve swelling in patients undergoing robot assissted laparoscopic prostatectomy with or without mannitolOptic nerve sheath diameter in patients undergoing robot assissted laparoscopic prostatectomy with or without mannitol- a randomised controlled studyCTRI/2021/10/037021
A study to compare efficacy of adding mannitol as an adjunct to lidocaine injection for surgical removal of impacted 3rd molarsANAESTHETIC EFFICACY OF COMBINATION OF 0.5 M MANNITOL AS AN ADJUVANT WITH LIDOCAINE WITH OR WITHOUT EPINEPHRINE IN INFERIOR ALVEOLAR NERVE BLOCK (IANB) FOR TRANSALVEOLAR EXTRACTION OF IMPACTED MANDIBULAR 3RD MOLARS: A RANDOMIZED CONTROL TRIALCTRI/2021/09/036617
Diuretic regimens in brain tumor surgeryLow dose mannitol with furosemide versus ordinary mannitol dose to reduce intracranial pressure in supra tentorial brain tumor surgery: comparative studyPACTR202003536095702
A Comparative Bronchial Provocation Study With Mannitol and Methacolinie in a Korean PopulationA Comparative Bronchial Provocation Study With Mannitol and Methacolinie in a Korean PopulationNCT02104284
Comparison of Hypertonic Saline and Mannitol on Brain Relaxation During Supratentorial Tumors ResectionComparison of Continuous Infusion of 3% Hypertonic Saline, Bolus of 3% Hypertonic Saline and Mannitol on Brain Relaxation During Supratentorial Tumor Resection: A Prospective, Randomized, Clinical StudyNCT04314674
MAnnitol for Blood Pressure Stability in HemoDialysis (MAP-HD)MAnnitol for Blood Pressure Stability in HemoDialysis (MAP-HD)NCT04428372
Role of the drug mannitol during operation involving removal of a part of the kidneyRole of intravenous mannitol in patients undergoing laparoscopic nephron-sparing surgery â?? A randomized double-blinded trial. - MINSSCTRI/2020/06/026081
Effectiveness of dilute rice water porridge as an oral solution (contrast) that helps in visualizing the intestines in the procedure of contrast enhanced computed tomography (CECT) of abdomenEffectiveness of dilute rice porridge vs. Mannitol as oral contrast agent in contrast enhanced computed tomography (CECT) abdomen; a randomized, triple-blind, parallel group trialCTRI/2020/07/026605
Evaluation of efficacy of intra articular injection of mannitol in patient with knee osteoarthritisEvaluation of efficacy of intra articular injection of mannitol versus hypertonic dextrose prolotherapy on decreasing pain and improvement of functions in patients with knee osteoarthritisIRCT20190912044756N1
Study to Gather Information on the Acceptability of a New Flavor System With Increasing Levels of 2, 4, 6 g or Higher of Mannitol for PEG 3350 in Subjects Having Infrequent Bowel Movements.A Single Center, Open-label, Parallel Arm, Phase 4 Study to Evaluate the Acceptability of a Prototype Flavor System With Ascending Levels of 2,4,6 Grams or Higher of Mannitol for PEG 3350 Laxative in Subjects Suffering With Occasional Constipation.NCT04534465
Effect of intravenous mannitol on post-operation pain following transforaminal lumar interbody fusion (TLIF)A single center, prospective, randomized, controlled study of effect of intravenous mannitol on pain of lumbar and lower limbs following transforaminal lumar interbody fusion (TLIF)ChiCTR2000039200
Measurement of intestinal permeability using lactulose and mannitol testMeasurement of intestinal permeability using lactulose and mannitol test - Measurement of intestinal permeability using lactulose and mannitol testJPRN-UMIN000043247
Cisplatin Containing Chemotherapy Regimens in Osteosarcoma and other Solid Tumors.: â??A Double Blind Randomized Controlled Trial of Renal Protective Effects of Normal Saline Plus Placebo Versus Normal Saline Plus Mannitol Prior to Cisplatin Containing Chemotherapy Regimens in Osteosarcoma and other Solid Tumorsâ??[CiNeMa]. - CiNeMaCTRI/2020/12/030115
Mannitol Use During Cadaveric Kidney TransplantationA Prospective, Randomized, Double Blinded, Placebo Control Trial to Evaluate Efficacy of Intravenous Mannitol Use During Cadaveric Kidney Transplantation Prior to Kidney ReperfusionNCT04705402
Retrograde Autologous Priming and Mannitol for Reducing Hemodilution in Cardiac SurgeryRetrograde Autologous Priming for Preserving Hemoglobin Peri-operatively With or Without Mannitol: A Pilot StudyNCT04870073
To compare the effect of mannitol and hypertonic saline on cardiac output in elderly patientsComparison of the Effect of Mannitol(20%) and Hypertonic Saline (3%) on advanced hemodynamic parameters in geriatric patients undergoing neurosurgical procedures: A Randomized Controlled TrialCTRI/2021/04/033185
Reference Ranges for the Cough Responsiveness to Inhaled MannitolReference Ranges for the Cough Responsiveness to Inhaled MannitolNCT05034367
The Effect of Intravenous Mannitol Plus Saline on the Prevention of Cisplatin-induced Nephrotoxicity: A Randomized, Double-blind, Placebo Controlled TrialThe Effect of Intravenous Mannitol Plus Saline on the Prevention of Cisplatin-induced Nephrotoxicity: A Randomized, Double-blind, Placebo Controlled TrialNCT04251689
Study on the effect and safety on the 'Dexamethasone–mannitol–hyperbaric oxygen' combination therapy for patients with delayed neurological sequelae after acute carbon monoxide poisoningStudy on the effect and safety on the 'Dexamethasone–mannitol–hyperbaric oxygen' combination therapy for patients with delayed neurological sequelae after acute carbon monoxide poisoningChiCTR2000029345
Effect of Intravenous Administration of Mannitol on ONSD in Patients With Raised ICPEffect of Intravenous Administration of 20% Mannitol on the Optic Nerve Sheath Diameter(ONSD) in Patients With Raised Intracranial PressureNCT04188353
Effect of mannitol 20% on the coagulation properties and platelet function in patients with craniotomy.Effect of mannitol 20% on the coagulation properties and platelet function in patients with craniotomy.DRKS00018947
Effectiveness of mannitol on postoperative complications after impacted mandibular third molar surgeryEffectiveness of mannitol on postoperative complications after impacted mandibular third molar surgeryIRCT20160712028892N2
A randomized phase II study of furosemide or mannitol in cisplatin-based chemotherapy using short hydrationA randomized phase II study of furosemide or mannitol in cisplatin-based chemotherapy using short hydration - A randomized phase II study of furosemide or mannitol in cisplatin-based chemotherapy using short hydrationJPRN-jRCTs051180015
Mannitol added with local anaesthesia for removal of lower 3rd molar tooth .EFFICACY OF 0.5M MANNITOL AS AN ADJUVANT WITH LIGNOCAINE WITH ADRENALINE FOR CLASSICAL INFERIOR ALVEOLAR NERVE BLOCK IN MANDIBULAR IMPACTED THIRD MOLAR EXTRACTIONS. RANDOMIZED CLINICAL TRIAL - nilCTRI/2024/01/061022
Efficacy and safety of paracetamol nerve block combined with TAPB nerve block in elderly patients undergoing gastrointestinal surgeryEfficacy and safety of paracetamol mannitol injection combined with TAPB nerve block in elderly patients undergoing gastrointestinal surgeryChiCTR2400079358
Effect of Paracetamol and Mannitol Injection on Postoperative Analgesia in Patients With Thoracoscopic LobectomyEffect of Paracetamol and Mannitol Injection on Postoperative Analgesia in Patients With Thoracoscopic LobectomyNCT06304181
Use of mannitol in CT enterography with their side effects evaluationAn open label randomized clinical trial to evaluating the efficacy of mannitol & water as endoluminal contrast agent in CT enterography and preventive measure to reduce adverse drug reactionCTRI/2024/02/063015
Safety, Tolerability and Effects of Mannitol in Parkinson's DiseaseA Phase II Single Center, Randomized, Double Blind and Placebo Controlled Study Assessing the Safety, Tolerability and Effects of Progressively Increased Dose of Oral Mannitol in Parkinson's DiseaseNCT03823638
Effect of Addition of Mannitol to Bupivacaine on IANB Success and Post-endodontic PainEffect of Addition of 0.5 Mol/L Mannitol to 0.5% Bupivacaine on IANB Success and Post-endodontic Pain in Mandibular Molars With Irreversible Pulpitis: A Randomized Clinical TrialNCT03749408
Efficacy of postoperative analgesia with intravenous paracetamol and mannitol injection combined with adductor canal block in total knee replacement surgery painEfficacy of postoperative analgesia with intravenous paracetamol and mannitol injection combined with adductor canal block in total knee replacement surgery painChiCTR2400081408
comparision of drug dexmedetomidine with mannitol drug on eye pressure and pressure in the brain on laparoscopic headdown surgeriesComparison of Dexmedetomidine with Mannitol on Intraocular Pressure and Optic Nerve Sheath Diameter changes as a Surrogate Marker of Intracranial Pressure in Laparoscopic Trendelenburg Surgeries : A Randomised Double Blind Controlled Study - nilCTRI/2024/04/066215
A domestic multi-center, real-world study to evaluate the safety and efficacy of acetaminophen mannitol injection in the treatment of postoperation painA domestic multi-center, real-world study to evaluate the safety and efficacy of acetaminophen mannitol injection in the treatment of postoperation painChiCTR2400083769
Mannitol Versus Nitroglycerin for Kidney Injury Prevention in Robotic-assisted Radical Prostatectomy or CystectomyThe Use of Intra-operative Mannitol Versus Nitroglycerin to Prevent Post-operative Acute Kidney Injury in Patients Undergoing Robotic-assisted Radical Prostatectomy or Cystectomy: A Randomized Controlled Trial.NCT06408597
Mannitol-induced Release of Copeptin in Healthy Adults and Patients With Polyuria-Polydipsia Syndrome (MARS Study)Mannitol-induced Release of Copeptin in Healthy Adults and Patients With Polyuria-Polydipsia Syndrome: a Double-blind, Randomized Crossover Proof-of-concept and Open-label Single Arm Pilot Study (MARS Study)NCT06542198
Efficacy of paracetamol and mannitol injection to prevent catheter-related bladder discomfort after holmium laser lithotripsy for ureteral calculiEfficacy of paracetamol and mannitol injection to prevent catheter-related bladder discomfort after holmium laser lithotripsy for ureteral calculiChiCTR2400087512
Effects of acetaminophen mannitol injection in perioperative multimodal analgesia and prevention of postoperative absorption fever in orthopaedic surgeryEffects of acetaminophen mannitol injection in perioperative multimodal analgesia and prevention of postoperative absorption fever in orthopaedic surgeryChiCTR2400088515
The effect of norepinephrine infusion on stroke volume variation(SVV) monitor in different fluid stage before and after mannitol infusion during neurosurgery.The effect of norepinephrine infusion on stroke volume variation(SVV) monitor in different fluid stage before and after mannitol infusion during neurosurgery.ChiCTR2300078002
Is hypertonic saline the medicine used for patients with head injury causing low sodium levels when compared to mannitolIs hypertonic saline causing delayed hyponatremia in traumatic brain injury patients undergoing osmotherapy – A randomized controlled trial between hypertonic saline and mannitol - NILCTRI/2024/10/075262
Which is better in management of increased intra cranial pressure among children, hypertonic (3%) saline (NaCl) or mannitol? An Experimental StudyHypertonic Saline Vs Mannitol in The Management of Raised Intracranial Pressure: A Single Blind Randomised Control Trial - ICP TRIALCTRI/2019/04/018788
To guide Mannitol therapy in Traumatic Brain Injury using Ocular Ultrasound.Optic Nerve Sheath Diameter guided Optimal Mannitol therapy for reduction of Intra Cranial Pressure in Traumatic Brain Injury Patients.CTRI/2019/07/019985
A clinical trial to study the effects of two drugs, 20% mannitol and Dexmedetomidine in decreasing intracranial pressure in patient undergoing laproscopic surgery.Comparison of the effect of 20% Mannitol andDexmedetomidine for prevention of the raisedintracranial pressure by evaluating Optic nerve sheathdiameter(ONSD) during Laproscopic surgery inTrendelenburg position.CTRI/2023/01/049044
Inhaled Mannitol on Mucociliary Clearance in Moderate to Severe Cystic FibrosisEffect of Bronchitol on Mucociliary Clearance in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)-Modulator Treated Patients With Cystic Fibrosis With Moderate to Severe Lung DiseaseNCT05740618
Comparing the effects of mannitol and hypertonic saline on blood coagulation in brain tumor patientsInvestigating the effects of the simultaneous use of Voluven (hydroxyethyl starch 0.4.130) plus 20% mannitol compared to Voluven plus 3% hypertonic saline on blood coagulation using PFA-100 in patients who are candidates for surgery for supratentorial brain tumors.IRCT20210506051200N2
Mannitol for stopping or preventing brain swelling (cerebral oedema) after stroke from bleeding in the brain (intracerebral haemorrhage): a feasibility studyMAnnitol for Cerebral oEdema after IntraCerebral Haemorrhage (MACE-ICH): a feasibility trialISRCTN15383301
The effect of two different doses of mannitol on the reduction of creatine phosphokinase in brain death patientsInvestigating the effect of two different doses of mannitol on reducing creatine phosphokinase (CPK) in brain death patients planned for organ donationIRCT20200825048515N67
A study comparing the effectiveness of 20% mannitol versus 3% saline to see if there is any difference in outcome of patients who are undergoing surgery for brain tumor.The impact of 3% hypertonic saline versus 20% mannitol on clinical outcomes in patients undergoing elective craniotomy for supratentorial tumours:a prospective randomized controlled trialCTRI/2019/09/021218
The Optimal Dose of Mannitol for Intraoperative Brain Relaxation During the Operation of Aneurysmal Subarachnoid HemorrhageStudy on the Optimal Dosage of Mannitol in Aneurysmal Subarachnoid Hemorrhage CraniotomyNCT04135456
Effectiveness of Mannitol Versus Polyethylene Glycol Electrolyte Dispersion as a Salve for Patients With Inadequate Bowel Preparation: a Randomized Controlled Clinical TrialEffectiveness of 1L Mannitol Versus 1L Polyethylene Glycol Electrolyte Dispersion as a Salve for Patients With Inadequate Bowel Preparation: a Randomized Controlled Clinical TrialNCT05912114
To evaluate the effects of same osmolar concentration of 20% mannitol, 3% hypertonic saline and 8.4% sodium bicarbonate on brain relaxation during surgery and vital parameters in patients undergoing surgery for brain tumors above tentorium cerebelliEvaluation of equiosmolar 20% mannitol, 3% hypertonic saline and 8.4% sodium bicarbonate on intraoperative brain relaxation and hemodynamic parameters in patients undergoing craniotomy for supratentorial tumors: A prospective randomized studyCTRI/2019/07/020483
Effect of acetaminophen mannitol injection on postoperative pain in thoracoscopic lung cancer patientsEffect of acetaminophen mannitol injection on postoperative pain in thoracoscopic lung cancer patients - noneChiCTR2300072623
Effect of paracetamol mannitol injection on postoperative chronic pain in patients undergoing thoracic surgeryEffect of paracetamol mannitol injection on postoperative chronic pain in patients undergoing thoracic surgeryChiCTR2300072869
Preoperative intravenous prophylactic analgesia with acetaminophen mannitol injection in breast surgery patients: A single center, randomized, controlled studyPreoperative intravenous prophylactic analgesia with acetaminophen mannitol injection in breast surgery patients: A single center, randomized, controlled studyChiCTR2300074555
Comparison of the efficacy of hypertonic saline 5% with mannitol 20% on cerebral edema in ischemic and hemorrhagic stroke patientsComparison of the efficacy of hypertonic saline 5% with mannitol 20% on cerebral edema in ischemic and hemorrhagic stroke patients: a randomized clinical trialIRCT20120215009014N480
Impact of the drug Mannitol on brain pressure during Video Prostate Removal SurgeryImpact of Mannitol on intracranial pressure, assessed using optic nerve sheath ultrasonography, during Videolaparoscopic ProstatectomyRBR-6xw6y4w
A prospective study on the effect of acetaminophen mannitol injection on postoperative rehabilitation quality in patients with gastrointestinal tumorsProspective study on the effect of different analgesia programs on postoperative rehabilitation quality of patients with gastrointestinal tumors - Effect of different analgesia programs on postoperative rehabilitation quality of patients with gastrointestinal tumorsChiCTR2300076213
Protective mechanism of mannitol on donor lung in lung transplantationProtective mechanism of mannitol on donor lung in lung transplantationChiCTR2300077351
Mannitol Improves Cerebral Oxygen SaturationEffect of Preoperative Mannitol Infusion on Cerebral Oxygen Saturation and Patients' Recovery After Laparoscopic CholecystectomyNCT02091180
A Pilot Study to Investigate Administration of Mannitol Via a Novel Dry Powder Inhaler DeviceA Pilot Study to Investigate the Tolerability of Inhaled Dry Powder Mannitol (IDPM) Administered Via a Novel Dry Powder Inhaler Device in Healthy Individuals and Subjects With Bronchiectasis.NCT00730977
Study to compare the extent to which brain matter is normal with a well known score in patients with cancer at posterior part of brain between two groups:those that receive Mannitol ( drug that has been shown to decrease brain swelling in other studies) with those that receive normal salineTo compare Brain Relaxation Score in Cerebello-Pontine Angle tumor surgeries using Mannitol with PlaceboCTRI/2019/05/018973
A Pilot Safety Study of Inhaled Dry Powder Mannitol in Acute Exacerbations of COPDA Pilot Safety Study of Inhaled Dry Powder Mannitol in Acute Exacerbations of COPDNCT00446667
Mannitol Versus Hypertonic Saline Solution in the Treatment of Elevated Intracranial PressureEquimolar Doses of Mannitol and Hypertonic Saline in the Treatment of Elevated Intracranial PressureNCT00447018
The study of small bowel cleaning by using senna, 20% mannitol, simethicone and three days fastingThe study of small bowel cleaning by using senna, 20% mannitol, simethicone and three days fastingChiCTR-DDT-14004402
A Pharmacokinetic and Bioavailability Study of Mannitol for Inhalation Using Normal SubjectsNCT00446771
Long Term Administration of Inhaled Dry Powder Mannitol In Cystic Fibrosis - A Safety and Efficacy StudyLong Term Administration of Inhaled Dry Powder Mannitol In Cystic Fibrosis - A Safety and Efficacy StudyNCT00446680
A Phase 2 Study to Determine the Safety and Efficacy of Inhaled Dry Powder Mannitol in Cystic FibrosisNCT00455130
Comparative trial between HyperHAES (7.2% sodio cloruro / 6% hydrxyethyl starch) and 20% mannitol for treatmenti intracranial hypertension in traumatic brain injury - OsmoBrainComparative trial between HyperHAES (7.2% sodio cloruro / 6% hydrxyethyl starch) and 20% mannitol for treatmenti intracranial hypertension in traumatic brain injury - OsmoBrainEUCTR2007-002005-45-IT
Long Term Administration of Inhaled Dry Powder Mannitol In Cystic Fibrosis – A Safety and Efficacy StudyLong Term Administration of Inhaled Dry Powder Mannitol In Cystic Fibrosis – A Safety and Efficacy StudyEUCTR2007-001412-23-IE
Effects of mannitol and hypertonic saline on cerebral oxygenation and metabolism in patients with posttraumatic intracranial hypertension.Effects of mannitol and hypertonic saline on cerebral oxygenation and metabolism in patients with posttraumatic intracranial hypertension. - mannitol and hypertonic saline in patients after traumatic brain injury.NL-OMON30018
The prevention of airway narrowing following dry powder mannitol inhalation in susceptible bronchiectatic patientsIn bronchiectatic patients susceptible to airway narrowing after inhaling dry powder mannitol is a single dose of sodium cromoglycate or eformoterol more effective than placebo in preventing airway narrowingACTRN12607000379415
Medical management of compartment syndromeRandomized double-blind placebo controlled clinicaltrial to determine the efficacy of mannitol in reducing intra-compartmental pressure - MRCS studyCTRI/2012/11/003089
A study examining the utility of inhaled mannitol as an additional therapy during an admission to hospital for an acute pulmonary exacerbation in children with cystic fibrosisA double blind, placebo-controlled, randomised study of inhaled mannitol during acute pulmonary exacerbation in children with cystic fibrosis – a pilot studyACTRN12612001167853
Use of Dry Powder Mannitol for the Treatment of Chronic RhinosinusitisPatients with chronic rhinosinusitis receiving intranasal mannitol powder, compared to standard medical therapies, to alleviate sinusitis symptoms.ACTRN12612001008819
Solutions comparison as kidney function protectors in patients undergoing a partial laparoscopic nephrectomyRandomized clinical trial to compare the effect of mannitol and hydroelectrolytic solutions as kidney function protector, in partial laparoscopic nephrectomies (MANCOL Study) - MANCOLEUCTR2012-003398-24-ES
Trial of inhaled mannitol in children with cystic fibrosisA randomised, multicentre, double-blind, placebo-controlled, crossover trial determining the efficacy of dry powder mannitol in improving lung function in subjects with Cystic Fibrosis aged six to seventeen years - DPM-CF-204 mannitol in CF aged 6-17 yearsEUCTR2012-002699-14-GB
Mannitol Use During Partial Nephrectomy Prior to Renal Ischemia and Impact on Renal Function OutcomesPhase 3 Trial of Intravenous Mannitol Use During Partial Nephrectomy Prior to Renal Ischemia and Impact on Renal Function OutcomesNCT01606787
Long Term Administration of Inhaled Dry Powder Mannitol In Cystic Fibrosis – A Safety and Efficacy StudyLong Term Administration of Inhaled Dry Powder Mannitol In Cystic Fibrosis – A Safety and Efficacy StudyEUCTR2006-004078-28-GB
Mannitol - Potential Role in Hemodialysis Initiation for Reduction of Intra-dialytic HypotensionPilot Study of Intravenous Mannitol During Hemodialysis Initiation to Reduce the Occurrence of Intra-dialytic Hypotension.NCT01520207
Mannitol (Aridol) and Methacholine (Provocholine) ResponsivenessMannitol and Methacholine Responsiveness: Effects of Deep InhalationsNCT01642745
A clinical trial to study the effects of two drugs,20% mannitol and 3% saline in children with raised intracranial pressure and acute central nervous system infections.COMPARISON OF 20% MANNITOL VS 3% SALINE IN CHILDREN WITH RAISED INTRACRANIAL PRESSURE DUE TO ACUTE CNS INFECTIONS: A PILOT RANDOMIZED CONTROLLED TRIALCTRI/2011/09/001997
Mannitol challenge test in adult asthma patients with fixed dose combination - PilotAn open-label single site single dose pilotstudy using mannitol challenge test with the purpose to explore treatment with fixed dose combinations in adult subjects with asthma in primary care in Sweden - Mannitol PilotEUCTR2011-000939-86-SE
Boron Phenylalanine With or Without Mannitol in Treating Patients With Glioblastoma MultiformeA Cancer Research UK Pharmacokinetic Study of BPA in Patients With High Grade Glioma to Optimize Uptake Parameters for Clinical Trials of BNCTNCT01233492
Assessment of bronchial hyperresponsiveness in children - inhalation of Mannitol compared to eucapnic voluntary hyperventilation and methacholine provocationAssessment of bronchial hyperresponsiveness in children - inhalation of Mannitol compared to eucapnic voluntary hyperventilation and methacholine provocationEUCTR2007-003543-67-SE
Steroid Titration Against Mannitol IN AsthmaTitrating Inhaled Steroid Dose Against Mannitol Hyper-responsiveness or BTS Outcomes: Comparative Effects on Asthma Exacerbations Over 1 YearNCT01216579
Mannitol Bronchoprovocation Challenge Ancillary Study/ACRNMannitol Bronchoprovocation Challenge Ancillary Study Protocol to Best Adjustment Strategy for Asthma Over Long TermNCT00585260
Effet comparé sur le débit sanguin et le métabolisme cérébral de deux types de prise en charge des accès d'hypertension intracrânienne après traumatisme crânien sévère : mannitol vs sérum salé hypertonique - MANNISELEffet comparé sur le débit sanguin et le métabolisme cérébral de deux types de prise en charge des accès d'hypertension intracrânienne après traumatisme crânien sévère : mannitol vs sérum salé hypertonique - MANNISELEUCTR2008-000209-12-FR
Long Term Administration of Inhaled Mannitol in Cystic FibrosisLong Term Administration of Inhaled Mannitol in Cystic Fibrosis- A Safety and Efficacy StudyNCT00630812
Effects of Hemofiltration and Mannitol Treatment on Cardiopulmonary-Bypass Induced ImmunosuppressionMechanisms of Endotoxin-Tolerance of Human Monocytes After CABG-Sugery - Effects of Hemofiltration and Mannitol TreatmentNCT00426192
Osmotic Therapy for Treatment of Intracranial Hypertension for Traumatic Brain Injury20% Mannitol vs 3% Hypertonic Saline in the Treatment of Intracranial Hypertension in Patients With Traumatic Brain Injury: A Double-blinded, Randomized TrialNCT01215019
Comparison of 20% Mannitol and 3% Hypertonic Saline for Cerebral Relaxation During Elective Supratentorial CraniotomiesComparison of the Efficacy Between 20% Mannitol and 3% Hypertonic Saline, Given as a Bolus at the Beginning of Elective Supratentorial Craniotomy for Tumor Resection, in Favoring Cerebral Relaxation Evaluated by a Sub-dural Intracranial Pressure Measurement.NCT01745081
Prevention Of Nephrotoxicity Following Bone Marrow Transplantation Using Urodilatin and MannitolPrevention Of Nephrotoxicity Following Allogeneic Bone Marrow Transplantation Using Urodilatin (Ularitide,Atrial Natriuretic Peptide) and Mannitol.NCT00390624
The effect of mannitol on intraoperative brain relaxation in patients with supratentorial tumor surgery: a randomized, double blind, parallel controlled trialThe effect of mannitol on intraoperative brain relaxation in patients with supratentorial tumor surgery: a randomized, double blind, parallel controlled trialChiCTR-TRC-13003984
Correlation of Measured and Calculated Serum Osmolality During Hyperosmolar Drugs Infusion in Patients After CraniotomyCorrelation of Measured and Calculated Serum Osmolality During Mannitol or Hypertonic Saline Infusion in Patients After CraniotomyNCT02037815
Double-blind Trial of Mannitol Cream to Block the Effect of Capsaicin CreamDouble-blind Trial of Mannitol Cream to Block the Effect of Capsaicin CreamNCT01963910
A review study to evaluate mannitol-assisted prophylaxis and treatment for acute promyelocytic leukemiaRetrospective study on mannitol-assisted prophylaxis and treatment for acute promyelocytic leukemiaISRCTN94954912
A pilot study of the effect of a hypertonic saline/dextran solution compared to mannitol in the management of raised intracranial pressureA pilot study of the effect of a hypertonic saline/dextran solution compared to mannitol in the management of raised intracranial pressureISRCTN82121210
A cross-over comparative study of inhaled mannitol, alone and in combination with daily rhDNase, in children with cystic fibrosis - Inhaled Mannitol in Cystic FibrosisA cross-over comparative study of inhaled mannitol, alone and in combination with daily rhDNase, in children with cystic fibrosis - Inhaled Mannitol in Cystic FibrosisEUCTR2004-001888-21-GB
Mannitol as Adjunct Therapy for Childhood Cerebral MalariaEffect of Mannitol as Adjunct Therapy on the Clinical Outcome of Childhood Cerebral Malaria in Mulago Hospital: A Randomised Clinical TrialNCT00113854
Efficiency of 7.2% hypertonic saline hydroxyethyl starch 200/0.5 versus mannitol 15% in the treatment of increased intracranial pressure in neurosurgical patientsISRCTN62699180
Aridol Challenge as a Tool to Predict Treatment Response to Inhaled Corticosteroids in COPDA Phase II Study to Investigate Mannitol Challenge as a Tool to Predict Treatment Response to Inhaled Corticosteroids in COPDNCT00117182
Mannitol Dose Response Study in Cystic FibrosisA Phase IIa Randomised, Open Label, Dose Response Study to Determine the Optimum Dose of Dry Powder Mannitol Required to Generate Clinical Improvement In Patients With Cystic FibrosisNCT00251056
Comparison of Inhaled Mannitol and rhDNase in Children With Cystic FibrosisA Cross-Over Comparative Study of Inhaled Mannitol, Alone and in Combination With Daily rhDNase, in Children With Cystic FibrosisNCT00117208
Prevention of Contrast-Induced NephropathyPrevention of Contrast-Induced Nephropathy: a Randomized Controlled Trial of Saline + Furosemide + Mannitol in High Risk Patients Undergoing Cardiac AngiographyNCT00175227
Bronchial Response to Mannitol and Inflammation in Steroid Naive Asthmatics.Bronchial Response to Mannitol and Inflammation in Steroid Naive AsthmaticsNCT00206973
Hypertonic Saline 75% vs Mannitol 20%Comparison of Equiosmolar Doses of Mannitol 20% Versus Hypertonic Saline 7.5% Infusion in the Reduction of Brain Bulk During Elective Craniotomies for Supratentorial Brain Tumor ResectionNCT00199511
Mannitol and nasal mucociliary clearanceA randomised, double-blind, placebo controlled trial of the effect versus placebo of twice daily doses of mannitol (80mg) for one week on nasal mucociliary clearance in healthy adults and adults with allergic rhinitis or chronic sinusitis.ACTRN12605000473662
Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain TumorsPhase I Dose Escalation Study of N-Acetylcysteine Administered in Conjunction With Carboplatin, Cyclophosphamide, and Etoposide Phosphate BBBD, in Children With Malignant Brain TumorsNCT00238173
Mannitol to prevent an exacerbation of Complex Regional Pain Syndrome (CRPS) after hand surgery.Mannitol to prevent an exacerbation of Complex Regional Pain Syndrome (CRPS) after hand surgery.NL-OMON25885
Safety and Efficacy of Bronchitol in BronchiectasisA Phase III Multicenter, Randomised, Parallel, Placebo-Controlled, Double-Blind Study to Investigate the Safety and Efficacy of Treatment With Bronchitol (Dry Powder Mannitol) in the Symptomatic Treatment of Bronchiectasis.NCT00277537
Monitoring inhaled corticosteroid efficacy in persons with asthma in pulmonary function laboratories.To determine if clinically relevant and statistically significant improvements in asthma control questionnaire score can be achieved and sustained by monitoring bronchial hyperresponsiveness (BHR) to inhaled mannitol in individuals with asthma when compared to assessing spirometry alone.ACTRN12613000988752
Methotrexate, Mannitol, Rituximab, and Carboplatin in Treating Patients With Newly Diagnosed Primary Central Nervous System LymphomaA Phase I/II Study of Patients With Newly Diagnosed Primary Central Nervous System Lymphoma Treated With Methotrexate/BBBD, and Adding Rituximab (an Anti CD-20 Antibody) and Carboplatin, to the Treatment RegimenNCT00293475
Carboplatin, Melphalan, Etoposide Phosphate, Mannitol, and Sodium Thiosulfate in Treating Patients With Previously Treated Brain TumorsPhase I/II Study of Carboplatin, Melphalan and Etoposide Phosphate in Conjunction With Osmotic Opening of the Blood-Brain Barrier and Delayed Intravenous Sodium Thiosulfate Chemoprotection, in Previously Treated Subjects With Anaplastic Oligodendroglioma or OligoastrocytomaNCT00303849
A phase III Multicenter, randomised, parallel, placebo-controlled, double-blind study to investigate the safety and efficacy of treatment with Bronchitol (dry powder mannitol) in the symptomatic treatment of bronchiectasis.A phase III Multicenter, randomised, parallel, placebo-controlled, double-blind study to investigate the safety and efficacy of treatment with Bronchitol (dry powder mannitol) in the symptomatic treatment of bronchiectasis.EUCTR2005-005452-41-GB
Sodium-Lactate and Traumatic Brain InjurySodium-Lactate Versus Mannitol in the Treatment of Intracranial Hypertensive Episodes in Severe Traumatic Brain Injured PatientsNCT00319345
Mannitol inhalations as a faster procedure for testing of airways hyperresponsiveness - Mannitol en AHRMannitol inhalations as a faster procedure for testing of airways hyperresponsiveness - Mannitol en AHREUCTR2006-003795-35-NL
The effect of mannitol in reducing brain edema and increasing the level of consciousness in patients with brain injuryEffect of 0.5, 1, 1.5 g / kg doses of monnitol 20% in reduction of brain edema and increase in post-traumatic consciousness level in patients with diffuse axonal injury accompanied with edema and brain midline shifting more than 5 mmIRCT2013040312888N1
Trial of Mannitol Cream for Pain Relief After a Long RunRandomized Trial of Mannitol Cream for Pain Relief After a Long RunNCT01843088
Mannitol inhalations as faster procedure for testing of airways hyperresponsiveness.Mannitol inhalations as faster procedure for testing of airways hyperresponsiveness.NL-OMON21125
A trial to determine the efficacy of dry powder mannitol in improving lung function in subjects with Cystic Fibrosis aged six to seventeen yearsA randomised, multicentre, double-blind, placebo-controlled, crossover trial determining the efficacy of dry powder mannitol in improving lung function in subjects with Cystic Fibrosis aged six to seventeen yearsNL-OMON21839
Determination of the pharmacokinetics of inhaled mannitol after single and multiple dosing in cystic fibrosis patientsDetermination of the pharmacokinetics of inhaled mannitol after single and multiple dosing in cystic fibrosis patientsEUCTR2008-008228-34-GB
Comparison of Two Different Medications Used to Treat Elevated Intracranial PressureProspective, Randomized Clinical Trialto Compare Mannitol and Hypertonic Saline for Treatment of Increased Intracranial PressureNCT00359697
A single-center, open label, randomized controlled trial of hypertonic saline vs mannitol to treat the brain edema in acute on chronic liver failureA single-center, open label, randomized controlled trial of hypertonic saline vs mannitol to treat the brain edema in acute on chronic liver failureChiCTR-TQR-13003788
Inhaled Mannitol as a Mucoactive Therapy for Bronchiectasis: A Phase III Multicenter, Randomized, Parallel Group, Controlled, Double Blind Study to Investigate the Safety and Efficacy of Inhaled Mannitol Over 12 Months in the Treatment of Bronchiectasis.NCT00669331
A phase III multicenter, randomized, parallel, controlled, double blind study to investigate the safety and efficacy of inhaled mannitol over 12 months in the treatment of bronchiectasis -EUCTR2008-002644-42-GB
Intal and Singulair, alone and in combination in asthma provoked by inhalation of a sugar.The effect of sodium cromoglycate alone, and in combination with montelukast sodium, on the airway sensitivity and recovery from challenge with inhaled mannitol in subjects with asthma.ACTRN12608000393358
Long Term Administration of Inahled Mannitol in Cystic Fibrosis - A Safety and Efficacy StudyLong Term Administration of Inahled Mannitol in Cystic Fibrosis - A Safety and Efficacy StudyEUCTR2008-002740-42-DE
Mannitol vs serum salé hypertonique en cas d'HTIC après traumatisme crânien grave: comparaison des effets sur la PtiO2 et le profil métabolique focal obtenu par microdialyse. - Mannitol vs SSH et microdialyse cérébraleMannitol vs serum salé hypertonique en cas d'HTIC après traumatisme crânien grave: comparaison des effets sur la PtiO2 et le profil métabolique focal obtenu par microdialyse. - Mannitol vs SSH et microdialyse cérébraleEUCTR2008-001698-14-FR
Effet comparé de deux doses de Mannitol sur l'hypertension intracrânienne. - Mannitol et trauma crânienEffet comparé de deux doses de Mannitol sur l'hypertension intracrânienne. - Mannitol et trauma crânienEUCTR2008-004979-21-FR
Essai MANHYPIC. Essai prospectif randomisé en double aveugle comparant l’effet de perfusions iso-osmolaire et iso-volumique de 250 mL de MANnitol 20% versus Sérum salé HYpertonique 3,9%, sur la Pression IntraCrânienne et la pression de perfusion cérébrale, au cours d’une poussée d’hypertension intracrânienne (HTIC) sévère chez des patients victimes d’un traumatisme crânien (TC) grave - MANHYPICEssai MANHYPIC. Essai prospectif randomisé en double aveugle comparant l’effet de perfusions iso-osmolaire et iso-volumique de 250 mL de MANnitol 20% versus Sérum salé HYpertonique 3,9%, sur la Pression IntraCrânienne et la pression de perfusion cérébrale, au cours d’une poussée d’hypertension intracrânienne (HTIC) sévère chez des patients victimes d’un traumatisme crânien (TC) grave - MANHYPICEUCTR2008-005134-75-FR
Pharmacokinetics of Inhaled Mannitol in Cystic Fibrosis PatientsDetermination of the Pharmacokinetics of Inhaled Mannitol After Single and Multiple Dosing in Cystic Fibrosis PatientsNCT00792714
A phase III multicentre, randomized, parallel, controlled, double blind study to investigate the safety and efficacy of inhaled mannitol over 12 months in the treatment of bronchiectasis. - DPM-B-305 Inhaled Mannitol in BronchiectasisA phase III multicentre, randomized, parallel, controlled, double blind study to investigate the safety and efficacy of inhaled mannitol over 12 months in the treatment of bronchiectasis. - DPM-B-305 Inhaled Mannitol in BronchiectasisEUCTR2008-008731-28-GB
Measurement of Exhaled Nitric Oxide (NO) and Bronchial Provocation Test With Mannitol as a Predictor of Response to Inhaled Corticosteroids in Chronic CoughMeasurement of Exhaled NO and Bronchial Provocation Test With Mannitol as a Predictor of Response to Inhaled Corticosteroids in Chronic CoughNCT00916526
Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell TumorsPhase I/II Study of Intra-Arterial Melphalan Given With Intra-Arterial Carboplatin, Osmotic Blood-Brain Barrier Disruption and Delayed Otoprotective Sodium Thiosulfate for Patients With Recurrent or Progressive CNS Embryonal or Germ Cell TumorsNCT00983398
High Dose Inhaled Mannitol StudyA Pilot Study to Investigate the Feasibility and Tolerability of Inhaling a High Dose of Dry Powder Mannitol (IDPM) Per Breath Administered Via a Dry Powder Inhaler Loaded With a Single Capsule in Subjects With BronchiectasisNCT01076491
Mannitol vs HS to Treat ICHT After Severe TBI : Comparison on PtiO2 and Microdialysis ValuesMannitol Versus Hypertonic Saline to Treat Intracranial Hypertension After Severe Traumatic Brain Injury : a Comparative Study on the Effects on PtiO2 and Microdialysis ValuesNCT01028339
Inhaled mannitol for the clearance of mucus in asthmaInhaled mannitol for the treatment of mucociliary dysfunction in patients with asthma - Its effect and mechanisms on the clearance of mucusACTRN12609001066279
Comparison of Two Doses of Mannitol on Brain Relaxation During Supratentorial CraniotomyComparison of Two Doses of Mannitol on Brain Relaxation During Supratentorial CraniotomyNCT01048684
Physiology of Cough in Asthma: Comparison of Sensory-Mechanical Responses to Mannitol and Methacholine Challenge TestsPhysiology of Cough in Asthma: Comparison of Sensory-Mechanical Responses to Mannitol and Methacholine Challenge TestsNCT01064245
A Clinical Trial to study the efficacy of Mannitol Capsules for Oral Inhalation manufactured by Ajanta Pharma Limited, as a bronchial provocation test to measure bronchial hyperresponsiveness verses Hypertonic (4.5 %) Saline in people both with and without sign and symptoms of asthma.An operator blinded, randomised, comparator multicentric study to evaluate the efficacy and safety of inhaled dry powder mannitol as a bronchial provocation test for airway hyperresponsiveness.CTRI/2009/091/000848
Double Blind Study of Hypertonic Saline vs Mannitol in the Management of Increased Intracranial Pressure (ICP).Double Blind Study of Hypertonic Saline vs Mannitol in the Management of Increased Intracranial Pressure (ICP).NCT01108744
Estudio aleatorizado, doble ciego y controlado sobre la eficacia de la albúmina y manitol en el cebado del sistema de circulación extracorpórea en cirugía cardiaca para reducir el sangrado postoperatorio y las necesidades transfusionalesA randomized, double-blind, controlled trial on efficacy of priming the cardiopulmonary bypass with albumin and mannitol to reduce postoperative bleeding and transfusional requirementsEstudio aleatorizado, doble ciego y controlado sobre la eficacia de la albúmina y manitol en el cebado del sistema de circulación extracorpórea en cirugía cardiaca para reducir el sangrado postoperatorio y las necesidades transfusionalesA randomized, double-blind, controlled trial on efficacy of priming the cardiopulmonary bypass with albumin and mannitol to reduce postoperative bleeding and transfusional requirementsEUCTR2008-008009-23-ES
Hypertonic Saline vs. Mannitol for Elevated Intercranial PressureHypertonic Saline vs. Mannitol for Elevated Intercranial PressureNCT01111682