IMPPAT Phytochemical information: 
Epigallocatechin

Epigallocatechin
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
"""Using Epigallocatechin Gallate (EGCG) and Cognitive Training to Modulate Cognitive Performance in Patients With Fragile X Syndrome"" (TESFX)"Estrogen Receptors Beta (ER-B) as Therapeutic Targets for the Improvement of Cognitive Performance in Fragile-X (TESXF)NCT01855971
Anti-sebum efficacy of moisturizer containing 2%L-carnitine and 5%epigallocatechin gallate for treatment of seborrheaAnti-sebum efficacy of moisturizer containing 2%L-carnitine and 5%epigallocatechin gallate for treatment of seborrheaTCTR20210908003
Epigallocatechin as an immunomodulatory and antineoplastic treatment in elderly patients with acute leukemia or mielodysplasiaEpigallocatechin (EGCG) as an immunomodulatory and antineoplastic treatment in elderly patients with AML or high-risk MDS inelegible for high-dose conventional chemotherapyRBR-3nvjx2k
Study of Oral Epigallocatechin-3-gallate (EGCG) in IPF PatientsDose Ranging Study of Oral Epigallocatechin-3-gallate (EGCG) Given Daily for 12 Weeks to Patients With Idiopathic Pulmonary Fibrosis (IPF) Evaluating Safety, PK Interactions With Standard of Care Drugs, and Biomarkers of Drug EffectNCT05195918
The Effect of the Association EGCG, Folic Acid and Vitamin B12 in Preventing the Persistence of HPV Infection.A Pilot Study to Test the Effect of the Association of Epigallocatechin Gallate (EGCG), Folic Acid and Vitamin B12 in Preventing the Persistence of Human Papilloma Virus (HPV) Infection.NCT06285357
Efficacy of a maintenance therapy with supplements containing indole-3-carbinol (I3C) and epigallocatechin-3-gallate (EGCG) in ovarian cancer patientsAn open randomized controlled clinical trial to evaluate the efficacy of a maintenance therapy with supplements containing I3C and EGCG in ovarian cancer patientsACTRN12616000394448
Normalization of dyrk1A and APP Function as an Approach to Improve Cognitive Performance and Decelerate AD Progression in DS Subjects: Epigallocatechin Gallate as Therapeutic ToolNormalization of dyrk1A and APP Function as an Approach to Improve Cognitive Performance and Decelerate AD Progression in DS Subjects: Epigallocatechin Gallate as Therapeutic ToolNCT01699711
Epstein-Barr Virus Reactivation and the Effect of EGCG on Virus Reactivation in Remission PatientsStudy of Epstein-Barr Virus Reactivation and the Effect of Dietary Supplement Epigallocatechin Gallate (EGCG) on Virus Reactivation in Remission Patients With Nasopharyngeal Carcinoma - A Randomized TrialNCT01744587
Epigallocatechin Gallate and Other Antural Compounds in HPV InfectionsTreatment With Epigallcoatechin Gallate, Hyaluronic Acid, Folic Acid and Vitamin B12 in Women HPV Positive With Abnormal Cytology TestsNCT06098456
Epigallocatechin-3-gallate (EGCG) in supportive and symptomatic treatment of patients with esophageal cancerEpigallocatechin-3-gallate (EGCG) in supportive and symptomatic treatment of patients with esophageal cancerChiCTR2100050444
The adjunctive use of (-)-epigallocatechin gallate (EGCG) subgingival irrigating solution with scaling and root planing in the management of chronic periodontitisThe adjunctive use of (-)-epigallocatechin gallate (EGCG) subgingival irrigating solution with scaling and root planing in the management of chronic periodontitisChiCTR2000029831
A Trial for the Treatment of Cardiac AL-Amyloidosis With the Green Tea Compound Epigallocatechin-3-gallate (TAME-AL)A Randomised Trial for the Treatment of Cardiac AMyloid Light-chain Amyloidosis With the Green Tea Compound Epigallocatechin-3-gallate (TAME-AL)NCT02015312
Comparison of the tear level between (-)-epigallocatechin gallate (EGCG) and (-)-epigallocatechin 3-O-(3-O-methyl) gallate (EGCG3"Me) after oral administration in healthy volunteers.Comparison of the tear level between (-)-epigallocatechin gallate (EGCG) and (-)-epigallocatechin 3-O-(3-O-methyl) gallate (EGCG3"Me) after oral administration in healthy volunteers. - Comparison of the tear level in green tea catechins after oral administration in healthy volunteers.JPRN-UMIN000034291
The effect of a substance in Green tea in the decrease of compounds formed in the food preparation process that affect human healthEffect of Epigallocatechin-3-Gallate on serum concentrations of Carboxymethyl-Lysine in Inflammation, Insulin Resistance and Endothelial dysfunction caused by acute ingestion of a meal high in advanced glycation end productsRBR-2b8p4n
Effect of the use of a catechin from green tea on the clinical performance of adhesives for dental restorationsEffect of epigallocatechin-3-gallate (EGCG) in the clinical performance of an universal adhesive system: a randomized clinical study.RBR-2hr94r
Effect of Epigallocatechin -3-gallate Supplementation in Traumatic Brain Injury PatientsEffect of Green Tea Epigallocatechin -3-gallate Supplementation on Traumatic Brain Injury Patients' OutcomesNCT02731495
Effects of EGCG (Epigallocatechin Gallate) in Chorea HuntingtonEffects of EGCG (Epigallocatechin Gallate) in Chorea Huntington - ETONEUCTR2010-023941-31-DE
Study of Epigallocatechin-3-gallate (EGCG) for Esophagus Protection in Patients With Lung Cancer Receiving Radial RadiotherapyNCT02577393
Study of Epigallocatechin-3-gallate (EGCG) for Skin Prevention in Patients With Breast Cancer Receiving Adjuvant RadiotherapyPhase II Study of Topical Epigallocatechin-3-gallate (EGCG) in Patients With Breast Cancer Receiving Adjuvant RadiotherapyNCT02580279
Treatment of cardiac amyloid light-chain amyloidosis with the green tea compound epigallocatechin-3-galiateA randomised trial for the Treatment of cardiac AMyloid light-chain amyloidosis with the green tea compound Epigallocatechin-3-gALlate (TAME-AL)ISRCTN68399350
Effects of glutamine and epigallocatechin-3-gallate on glucose tolerance, markers of inflammation, oxidative stress and procoagulant status in Type 2 diabetes mellitusEffects of glutamine and epigallocatechin-3-gallate on glucose tolerance, markers of inflammation, oxidative stress and procoagulant status in Type 2 diabetes mellitus - Glutamine and EGCG in type 2 diabetes mellitusNL-OMON38189
Epigallocatechingallate (EGCG) in Cardiac AL AmyloidosisA Phase II Open-label Randomized Study of Dietary Supplement With Epigallocatechin Gallate (EGCG) to Improve Cardiac Dysfunction in Patients With AL Amyloidosis Who do Not Require Chemotherapy (EpiCardiAL)NCT01511263
Treatment of Endometriosis with Epigallocatechin gallate: a double-blind randomized placebo-controlled crossover pilot trial.Treatment of Endometriosis with Epigallocatechin gallate: a double-blind randomized placebo-controlled crossover pilot trial. - TEE- studyNL-OMON39170
EGCG Improves Acne by Modulating Molecular TargetsEpigallocatechin-3-Gallate Improves Acne in Humans by Modulating Intracellular Molecular Targets and Inhibiting P. AcnesNCT01687556
Study of Epigallocatechin-3-gallate (EGCG) for Supportive and Symptomatic Management in Patients With Esophageal CancerStudy of Epigallocatechin-3-gallate (EGCG) for Supportive and Symptomatic Management in Patients With Esophageal CancerNCT05039983
A trial investigating the use of Veregen (EPIgallocatechin-3-gallate) in the treatment of Vulval Intraepithelial NeoplasiaPhase II clinical trial investigating the use of EPIgallocatechin-3-gallate (Veregen) in the treatment of Vulval Intraepithelial NeoplasiaISRCTN98495886
Effect of epigallocatechin on antibody-producing ability and immunostimulatory activity after influenza vaccinationEffect of epigallocatechin on antibody-producing ability and immunostimulatory activity after influenza vaccination - Epigallocatechin and immune response to influenza vaccinationJPRN-UMIN000012941
Role of Epigallocatechin for the Prevention of Infections in Patients Treated with ImmunoSuppressive TherapyRole of Epigallocatechin for the Prevention of Infections in Patients Treated with ImmunoSuppressive Therapy - Role of EpigalloCAtechin for the prevention of infections in patients treated with immunoSuppressive Therapy (RECAST)JPRN-UMIN000013344
Effect of epigallocatechin gallate on postprandial blood glucose and insulin levelEffect of epigallocatechin gallate on postprandial blood glucose and insulin levelChiCTR2400085567
Influence of Piperine on the bioavailability of epicatechin and epigallocatechin - a pilot studyInfluence of Piperine on the bioavailability of epicatechin and epigallocatechin - a pilot study - E-Pip-PilotDRKS00020741
Comparative Evaluation of Nanohydroxyapatite & EGCG mix versus Biodentine for Indirect Pulp Therapy in Young Permanent TeethComparative Evaluation Of Indirect Pulp Therapy In Young Permanent Teeth Using Nanohydroxyapatite And Epigallocatechin-3-Gallate (EGCG) Mix Versus Biodentine: A Randomized Controlled Trial - NILCTRI/2025/03/082145
Curcumin and EGCG Supplementation to Improve Serum BDNF and Mood DisturbanceA Randomized Controlled Trial to Determine the Effects of Curcumin and Epigallocatechin Gallate Supplementation on Serum Brain Derived Neurotrophic Factor and Mood Disturbance in AdultsNCT06531863
A Phase II Clinical Study of Epigallocatechin-3-gallate in Patients With Esophageal Squamous CancerEfficacy and Safety of Epigallocatechin-3-gallate, an Important Polyphenolic That Originates From Tea, in Patients With Esophageal Squamous Cancer: A Phase II TrialNCT06398405
Evaluation of Oral EGCG Treatment for L-SIL Associated With HPV InfectionEvaluation of Oral Epigallocatechin Gallate Treatment for Low-grade Cervical Lesions (L-SIL) Associated With Human Papilloma Virus (HPV) InfectionNCT06314113
Reducing Frailty for Older Cancer Survivors Using Supplements IIA Phase 2 Randomized Controlled Trial of Epigallocatechin-3-Gallate (EGCG) on Frailty and Inflammation in Older Survivors of CancerNCT06068543
The effect of epigallocatechin gallate loaded nanostructured lipid carriers on oral lichen planusThe effect of epigallocatechin gallate (extracted from green tea) loaded nanostructured lipid carriers on the treatment of oral lichen planusIRCT20230823059238N1
EGCG for Hepatocellular Carcinoma ChemopreventionPhase II Randomized Controlled Trial of Epigallocatechin Gallate for Hepatocellular Carcinoma ChemopreventionNCT06015022
Effects of treatment with FOPCON in patients with Fibrodysplasia Ossificans ProgressivaClinical, biochemical and molecular aspects in patients with Fibrodysplasia Ossificans Progressiva before and after treatment with ascorbic acid, propranolol, hesperidine and epigallocatechinRBR-9dkn9ry
Effect of Epigallocatechin-3-Gallate Solution as a Root Canal Irrigant on Post-Operative Pain Intensity and Bacterial Load Reduction in Necrotic ToothEffect of Epigallocatechin-3-Gallate Solution Versus Sodium Hypochlorite as a Root Canal Irrigant on Post-Operative Pain Intensity and Bacterial Load Reduction in Asymptomatic Necrotic Mandibular Premolars: A Randomized Clinical TrialNCT05988788
Epigallocatechin Gallate (EGCG) as a Flushing Agent During Full Pulpotomy in Mature Permanent Molars With Irreversible PulpitisThe Influence of Epigallocatechin Gallate (EGCG) as a Flushing Agent During Full Pulpotomy Using Two Different Calcium Silicate-based Materials on Postoperative Pain and Success Rate in Mature Permanent Molars With Irreversible Pulpitis: A Randomized Clinical TrialNCT05811403
Comparative Efficacy of Gingival Application of Injectable Platelet Concentrate and Green Tea Gel as an Add-On in the treatment of PeriodontitisComparative Efficacy of Local Subgingival Application of Injectable Platelet Rich Fibrin and (-)-Epigallocatechin Gallate Gel as an Adjunct to Scaling and Root Planing: A Randomized Controlled Clinical TrialCTRI/2022/09/045964
SUNIMUD - Sunphenon EGCg (Epigallocatechin-Gallate) in Duchenne Muscular DystrophySUNIMUD - Sunphenon EGCg (Epigallocatechin-Gallate) in Duchenne Muscular Dystrophy - SUNIMUDEUCTR2009-016482-28-DE
Vitamin D, Epigallocatechin Gallate, D-chiro-inositol and Vitamin B6 in Uterine FibroidThe Use of Vitamin D in Combination with Epigallocatechin Gallate, D-chiro-inositol and Vitamin B6 in the Treatment of Women with Uterine FibroidNCT05448365
Efficacy and Safety of Cream containing Dipotassium Glycyrrhizinate, Vaccinium Myrtillius, Epigallocatechin Gallatyl Glucoside, Tamarindus Indica Compared with Triamcinolone acetonide Cream in the treatment of eczema and plaque psoriasisEfficacy and Safety of Cream containing Dipotassium Glycyrrhizinate, Vaccinium Myrtillius, Epigallocatechin Gallatyl Glucoside, Tamarindus Indica Compared with Triamcinolone acetonide Cream in the treatment of eczema and plaque psoriasisTCTR20211025002
Effect of Bromelain , Curcumin and Epigallocatechin in the treatment of outpatient Covid-19 patientsA Randomized, Double-blind, Placebo-controlled study to Evaluate the Efficacy and Safety of the Bromelain, Curcumin and Epigallocatechin in the treatment of outpatient Covid-19 patientsIRCT20210724051971N1
Reducing Frailty for Older Cancer Survivors Using SupplementsReducing Frailty for Older Cancer Survivors Using Supplements (ReFOCUS): A Phase 2 Randomized Controlled Trial of Epigallocatechin-3-Gallate (EGCG) on Frailty and Inflammation in Older Survivors of CancerNCT04553666
Clinical evaluation of the effect of epigallocatechin-3-gallate in the restorative treatment of non-carious lesionsClinical evaluation of the effect of Epigallocatechin-3-gallate in the restorative treatment of Abfraction lesionsRBR-772thc
Effects of epigallocatechin gallate (EGCG) and Cissus Quadrangularis extract on adiposity, metabolic profiles, serum leptin, and resting metabolic rateEffects of epigallocatechin gallate (EGCG) and Cissus Quadrangularis extract on adiposity, metabolic profiles, serum leptin, and resting metabolic rateTCTR20200422001
The effect of chlorhexidine and Epigallocatechin Gallate in ultrasonic instrumentation of advanced periodontitis patientsThe effect of chlorhexidine and Epigallocatechin Gallate in ultrasonic instrumentation of advanced periodontitis patientsChiCTR2000029911
Effect of Epigallocatechin Gallate supplementation on type 2 diabetesEffects of Epigallocatechin Gallate Supplementation on the Insulin Resistence and Inflammatory Factors in Patients with Type 2 DiabetesIRCT20181219042047N1
Impact of Ketone Bodies and Epigallocatechin Gallate in Multiple SclerosisImpact of Ketone Bodies and Epigallocatechin Gallate in Multiple SclerosisNCT03740295
Effect of Green Tea on StrokeThe effect of powdered green tea enriched with epigallocatechin gallate (EGCG) on some clinical, biochemical, inflammatory, antioxidant and cognitive parameters in stroke patients; a double-blind, placebo-controlled clinical trialIRCT20180902040927N1
Effect of Epigallocatechin Gallate supplementation on type 2 diabetesStuding the effects of Epigallocatechin Gallate supplementation on lipid profile, Insulin resistance, Oxidative stress and inflammatory factors in rs9939609 FTO gene variants in type 2 diabetic patients.IRCT2017021612949N3
Chemopreventive Effects of Epigallocatechin Gallate (EGCG) in Colorectal Cancer (CRC) PatientsA Pilot Study to Evaluate the Chemopreventive Effects of Epigallocatechin Gallate (EGCG) in Colorectal Cancer (CRC) Patients with Curative Resections.NCT02891538
Epigallocatechin Gallate Lowers Circulating Catecholamine Concentrations and Alters Lipid Metabolism.The Polyphenol Epigallocatechin Gallate Lowers Circulating Catecholamine Concentrations and Alters Lipid Metabolism During Graded Exercise in Man.NCT03199430
Epigallocatechin Gallate (EGCG) to Improve Cognitive Performance in Foetal Alcohol Syndrome (FAS) ChildrenEpigallocatechin Gallate (EGCG) as Therapeutic Tool to Improve Cognitive Performance in Foetal Alcohol Syndrome (FAS) ChildrenNCT02558933
Effects of Vitamin D, Epigallocatechin Gallate, Vitamin B6, and D-Chiro-inositol Combination on Uterine FibroidsEffects of Vitamin D, Epigallocatechin Gallate, Vitamin B6, and D-Chiro-inositol Combination on Uterine Fibroids: a Randomized Controlled TrialNCT05409872
Effects of Epigallocatechin Gallate (EGCG) in Healthy, Young AdultsCerebral Blood Flow, Cerebro-electrical Activity and Behavioural Effects of Epigallocatechin Gallate (EGCG) Administration in Healthy, Young AdultsNCT00981292
Effect of EGCG on the Body's Response to InsulinAn Exploratory Study to Evaluate the Ability of Epigallocatechin Gallate to Simultaneously Improve Metabolic and Cardiovascular Actions of Insulin in Healthy and Obese SubjectsNCT00434499
Sunphenon EGCg (Epigallocatechin-Gallat) in the early stage of Alzheimer´s Disease - SUN-AKSunphenon EGCg (Epigallocatechin-Gallat) in the early stage of Alzheimer´s Disease - SUN-AKEUCTR2009-009656-20-DE
Green Tea, High in Epigallocatechin Gallate (EGCG) and Postprandial Fat OxidationEffects of the Green Tea Extract TEAVIGO High in EGCG, on Postprandial Fat Oxidation in Overweight VolunteersNCT00867555
Sunphenon (Epigallocatechin-Gallate) in relapsing-remitting multiple sclerosis - Sunphenon in RR-MSSunphenon (Epigallocatechin-Gallate) in relapsing-remitting multiple sclerosis - Sunphenon in RR-MSEUCTR2006-006323-39-DE
Effect of Epigallocatechin-Gallate on Inner Retinal Function in Ocular Hypertension and Early GlaucomaFunctional Effects of Epigallocatechingallate on Retinal Function in GlaucomaNCT00476138
Sunphenon EGCg (Epigallocatechin-Gallate) in the Early Stage of Alzheimer´s DiseaseSunphenon EGCg (Epigallocatechin-Gallate) in the Early Stage of Alzheimer´s DiseaseNCT00951834
The acute effects of a green tea extract, -Epigallocatechin Gallate (EGCG) on cognition, stress, brain function and cardiovascular function.An investigation into the acute effects of -Epigallocatechin Gallate (EGCG) on cognition, stress, brain function and cardiovascular function in healthy adults.ACTRN12609000646246
Behandeling van endometriose met groene thee: Een dubbel blind gerandomiseerde placebo gecontroleerde pilot studie.Treatment of endometriosis with epigallocatechin gallate: A double-blind randomized placebo-controlled pilot trial.NL-OMON20203
Sunphenon in Progressive Forms of Multiple SclerosisMonocentric, Prospective, Doubleblind, Randomised/Stratified, Placebocontrolled Two-arm Study to Evaluate the Effect of Sunphenon EGCg (Main Component Epigallocatechin-Gallat) on the Increase of Brain Atrophy in the Cerebral Magnetic Resonance Tomography in a 36-months Treatment Time in Patients With Primary or Secondary Chronic-progressive Multiple SclerosisNCT00799890
Sunphenon Epigallocatechin-Gallate (EGCg) in Duchenne Muscular DystrophySunphenon Epigallocatechin-Gallate (EGCg) in Duchenne Muscular DystrophyNCT01183767