| Neurodynamics of Prosocial Emotional Processing Following Serotonergic Stimulation With N,N-Dimethyltryptamine (DMT) and Harmine in Healthy Subjects | Neurodynamics of Prosocial Emotional Processing Following Serotonergic Stimulation With N,N-Dimethyltryptamine (DMT) and Harmine in Healthy Subjects | NCT04716335 |
| Effects of Dimethyltryptamine in Healthy Subjects | Effects of Dimethyltryptamine (DMT) in Healthy Subjects: A Placebo-controlled Cross-over Study | NCT04353024 |
| Clinical Study of DMT in Healthy Adults | Inhaled N, N-Dimethyltryptamine: a Phase I Study in Healthy Adults | NCT05573568 |
| Safety and Tolerability of DMT in Healthy Adults | Inhaled N,N-Dimethyltryptamine: a Safety and Tolerability Study in Healthy Adults | NCT05901012 |
| The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD) | The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD) | NCT06070649 |
| Safety, Tolerability and Antidepressant Effects of DMT in Patients With Depression | An Open Label Trial of Inhaled N,N-Dimethyltryptamine in Patients With Partial Response in Depression. | NCT06094907 |
| Safety, blood levels and effects of N,N-dimethyltryptamine [DMT (SPL026)] in healthy participants that have taken psychedelic substances before (Part A) and in healthy participants with little to no psychedelic experience (Part B) | An open-label, cross-over study of intramuscular (IM) and intravenous (IV) doses of SPL026 drug product (DMT fumarate [a serotonergic psychedelic]), in healthy, psychedelic-experienced subjects (Part A: IM and IV doses) and subjects with little to no psychedelic experience (Part B: IM dose only) | ISRCTN63723571 |
| Understanding Neuroplasticity Induced by TrYptamines (UNITy): the effects of dimethyltryptamine (DMT) on drinking | A randomised, placebo-controlled experimental study of dimethyltryptamine on alcohol reward memory in non-treatment-seeking excessive drinking: effects on drinking, therapeutic mechanisms and neural biomarkers | ISRCTN13970288 |