IMPPAT Phytochemical information: 
Eugenol

Eugenol
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
Effect of different herbal infused tooth brush on gingival health.Comparison of Plaque Removal, Wear Index and salivary parameters among tulsi Infused, eugenol infused and Nylon Toothbrushes: A Randomized Control trial. - NilCTRI/2023/11/059647
Effect of Myristica fragrans in Pulp therapy of Primary teethComparative Evaluation of Myristica fragrans efficacy as a pulpotomy medicament with Mineral trioxide aggregate and with Zinc oxide Eugenol as an obturating material in Primary teeth (for Humans).CTRI/2020/05/025148
Obturating materials in pulpectomy of primary molarsComparative Evaluation of Zinc Oxide - Eugenol with Zinc Oxide - Myristica Fragrans Oil Mixture & Zinc Oxide - Ozonated Oil Mixture as Obturating Materials in Primary Molars: A Randomized Clinical TrialCTRI/2023/08/056054
Efficacy of a Eugenol-based Product to Improve the Quality of Toothbrushing and Relieving Gum Discomfort AreasClinical Investigation to Assess the Efficacy of a Eugenol-based Product in Improving the Quality of Toothbrushing Measured by Plaque Assessment and Patient Perception Questionnaire and Relieving Gum Discomfort AreasNCT06366568
A study comparing Zinc Oxide-Propolis, Ozonated Oil-Zinc Oxide and Zinc Oxide Eugenol for filling the root canals of infected posterior milk teeth in childrenAn in vivo comparative evaluation of Zinc Oxide-Propolis, Ozonated Oil-Zinc Oxide and Zinc Oxide Eugenol as obturating materials in primary molars - nilCTRI/2024/08/072885
A clinical trial to evaluate the treatment outcome of two medications used as root canal filling materials in children with primary tooth infections.Evaluation of treatment outcome in terms of clinical and radiographic presentation of Chitra HAP-fil TM and Zinc oxide Eugenol as pulpectomy medicaments in primary mandibular molars- A Randomised controlled trial. - NILCTRI/2024/09/073303
A study to develop a method to analyse the uptake and degradation of a spice and flavouring agent known as eugenolA single-centre, open-label study for the collection of urine samples as part of a method development and validation process for eugenol biomarkers in healthy male volunteersISRCTN67240844
Comparing Pain After Single-Visit Root Canal Treatments Using New Curcumin Sealers vs Traditional Sealers in Infected Teeth: A StudyComparative Analysis of Postoperative Pain in Single-Visit Endodontic Treatment using CurowhiteTM Enhanced Sealers versus Zinc Oxide Eugenol Sealer in mandibular premolars: A Randomized Controlled Trial - NILCTRI/2025/02/080129
Comparing Zinc Oxide Eugenol and Biosealer for Primary Tooth Root Canal Treatment: A Clinical StudyClinical and Radiographic Evaluation of Zinc Oxide Eugenol and Biosealer as Obturating Material in Primary Teeth: An In-Vivo Comparative Study - ZOE-BioSeal TrialCTRI/2025/03/081790
Optimizing Pulpectomy: A Battle of Obturants in Primary MolarsComparative Analysis of Obturation Outcomes in Primary Mandibular Molar using Novel Obturating Material versus Iodocal versus Zinc Oxide Eugenol . A Randomised Controlled Clinical TrialCTRI/2025/04/084603
A study comparing two different filling materials used in baby teeth after root canal treatment over a period of 12 monthsClinical And Radiographical Assessment Of Endoflas+ Eugenol And Endoflas+Propolis As Obturating Material In Primary Molars A 12 Months Follow Up Study - nillCTRI/2025/05/087638
A comparison between a typical dressing and an absorbed dressing after surgical removal of gum pigmentationA comparison between eugenol-free dressing (Coe-Pack) and absorbed dressing (Reso-Pac) after surgical removal of gingival pigmentation (spilt mouth study)ISRCTN76318940
Evaluation of Zinc Oxide with Tea Tree oil as Root canal filling material over zinc oxide eugenol in Primary teethClinical and Radiographic evaluation of the Efficacy of Zinc Oxide with Tea Tree Oil as Obturation material In Primary Teeth - An invivo StudyCTRI/2020/09/027990
A Comparative Single Blind Clinical Study on the Effect of Alvogyl, Eugenol, and Nigella Sativa (Black Seed Oil) for Alveolar Osteitis.A Comparative Single Blind Clinical Study on the Effect of Alvogyl, Eugenol, and Nigella Sativa (Black Seed Oil) for Alveolar Osteitis.NCT06823544
assessment of cement filling inside the teethRadiographic assessment of obturation in primary molars with zincoxide power with nigella sativa and eugenol oil - an invivo studyCTRI/2023/03/050662
Use of chitosan as periodontal dressing following periodontal flap surgery"""Comparativce evaluation of gingival tissue response following placement of chitosan and a non-eugenol dressing after periodontal flap surgery:A comparative clinical study"""CTRI/2020/04/024645
Comparative clinical and X-ray evaluation of mixtures of Zinc oxide â?? tulsi extract, Zinc oxide - ozonated oil and Zinc oxide eugenol as root canal filling materials in milk teethComparative clinical and radiographic evaluation of mixtures of Zinc oxide â?? tulsi extract, Zinc oxide - ozonated oil and Zinc oxide eugenol as obturating materials in primary molars: An in vivo studyCTRI/2022/01/039464
Effect of Non-eugenol Periodontal Pack With and Without PRF on Post-operative Pain and Wound Healing After Gingival DepigmentationClinical Comparison of the Effect of Non-eugenol Containing Periodontal Pack With and Without Platelet Rich Fibrin on Post-operative Pain and Wound Healing After Surgical Gingival Depigmentation: A Randomized Clinical TrialNCT04495205
Comparing the healing and pain relief effects of Elephant creeper, Turmeric, Triphala, and COE-PAK after periodontal flap surgeryComparing the effect of Argyreia speciosa gel, Curcumin gel, Triphala gel and non- eugenol periodontal dressing on wound healing and pain post periodontal flap surgery-A randomized clinical trial - NILCTRI/2025/04/085848
Endodontic Medications for Irreversible Pulpitis: Articaine or Eugenol?Articaine or Eugenol: a Study on the Choice of Endodontic Medication in the Emergency Management of Irreversible Pulpitis of a Mature Permanent ToothNCT03472456
Root canal treatment in primary molars with necrotic pulp using two different pulp therapiesPulp therapy in necrotic primary molars using CTZ paste and Zinc Oxide-Eugenol paste - a randomized controlled clinical trialRBR-8xt8wx
A Clinical Trial Comparing FS With ZOE and Non-eugenol Based Materials in Primary Teeth PulpotomiesA Comparative Assessment Clinical Trial Comparing Ferric Sulfate With Zinc-oxide Eugenol and Non-eugenol Based Materials for Pulpotomy in Primary Molar TeethNCT05557812
Clinical and radiographic evaluation of “Endoflas” versus “Zinc Oxide and Eugenol” as root canal filling material in primary molars: A randomized controlled trial.Clinical and radiographic evaluation of “Endoflas” versus “Zinc Oxide and Eugenol” as root canal filling material in primary molars: A randomized controlled trial.PACTR201812884054327
Comparative evaluation of bone healing after root canal treatment using BioRoot RCS,AH Plus and Zinc Oxide Eugenol as root canal sealersComparative evaluation of periapical healing after root canal treatment using three different endodontic sealers â?? a randomised control trialCTRI/2018/10/015919
Evaluation of effectiveness of ozone oil dressing and zinc oxide eugenol dressing in treatment of dry socket.Effectiveness of ozonated oil dressing versus zinc oxide eugenol dressing in management of alveolar osteitis.CTRI/2019/09/021189
Evaluation of zinc oxide -turmeric extract dressing after periodontal surgery in chronic periodontitis patientsA Randomized Clinical Trial evaluating Curcumin enhanced non-eugenol dressing post surgery in the treatment of Chronic Periodontitis. An In vitro & In vivo studyCTRI/2020/01/022707
Comparison of zinc oxide eugenol and metapex as root canal filling material following pulpectomy in primary molarsComparison of zinc oxide eugenol and metapex as root canal filling material following pulpectomy in primary molars of children aged 4-9 years oldACTRN12623000785606
To compare three different root canal filling material in ChildrenA Clinical and Radiographic Comparative Study Between Zinc Oxide Eugenol Syzygium cumini Mixture, Zinc Oxide Eugenol Propolis Mixture And Zinc Oxide Eugenol As Obturating Materials in Primary Molars: A Randomized Controlled Trial.CTRI/2021/12/038942
Effect of topical application of eugenol on dental sensitivity caused by in-office dental bleachingEffect of topical eugenol application on dental sensitivity caused by in-office bleachingRBR-23ch2p
Post-treatment flare-up after using nano zinc oxide eugenol sealerPost-treatment flare-up incidence after using nano zinc oxide eugenol sealer in mandibular first molars with irreversible pulpitisIRCT20190103042224N1