IMPPAT Phytochemical information: 
Fenretinide

Fenretinide
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
A Randomized, Double-blind Study of the Effects of Fenretinide Administered in Subjects With ObesityPhase 2 Study of the Assessment of the Insulin Sensitizing Activity of Fenretinide in Subjects With Insulin Resistance With BMI >30Kg/m2, and Liver Inflammation Related to Non-alcoholic Fatty LiverNCT00546455
Fenretinide and Rituximab in Treating Patients With B-Cell Non-Hodgkin LymphomaA Phase I-II Trial of Fenretinide (4-HPR) + Rituximab in Patients With B-cell LymphomaNCT00288067
ST-001 nanoFenretinide in Relapsed/ Refractory Small Cell Lung CancerA Phase 1a/1b Trial in Relapsed/Refractory Small Cell Lung Cancer to Determine the Safety Profile, Pharmacology, and Maximum Tolerated Dose of ST-001, a Fenretinide Phospholipid Suspension (12.5 mg/mL) for Intravenous InfusionNCT06922539
N2004-04: Fenretinide LXS in Treating Patients With Recurrent, Refractory, or Persistent NeuroblastomaPhase I Study of Fenretinide (4-HPR, NSC 374551) Lym-X-Sorb™ (LXS) Oral Powder in Patients With Recurrent or Resistant NeuroblastomaNCT00295919
Fenretinide in Treating Patients With Metastatic or Unresectable Malignant Solid TumorsPhase I Trial of Intravenous Fenretinide (4-HPR) for Patients With Malignant Solid TumorsNCT00387504
Study of Fenretinide in the Treatment of Geographic Atrophy Associated With Dry Age-Related Macular DegenerationA Phase II Multicenter, Randomized, Double-Masked, Placebo-Controlled, Dose-Comparison Study of the Safety and Efficacy of Fenretinide in the Treatment of Geographic Atrophy in Subjects With Age-Related Macular DegenerationNCT00429936
Bexarotene and Fenretinide as Addition to Antipsychotic Treatment in Schizophrenia PatientsComparison Efficacy of Bexarotene and Fenretinide as Addition to Antipsychotic Treatment in Schizophrenia Patients: Double-blind Placebo Controlled StudyNCT00534898
Fenretinide Lym-X-Sorb™ in Treating Patients With Recurrent or Resistant Solid Tumors or LymphomaPhase I Trial of Fenretinide (4-HPR, NSC 374551) Lym-X-Sorb™ (LXS) Oral Powder (4-HPR/LXS Oral Powder) (4-HPR) in Adults With Solid Tumors and LymphomasNCT00589381
N2004-03: Intravenous Fenretinide in Treating Young Patients With Recurrent or Resistant NeuroblastomaA Phase I Study of Intravenous (Emulsion) Fenretinide in Children With Recurrent or Resistant NeuroblastomaNCT00646230
Breast cancer prevention with fenretinide in young women at genetic and familial risk. A phase III randomized clinical trial - NDBreast cancer prevention with fenretinide in young women at genetic and familial risk. A phase III randomized clinical trial - NDEUCTR2009-010260-41-IT
Fenretinide in Children With Recurrent/Resistant ALL, AML, and NHL"A Phase I Study of Intravenous (Emulsion) Fenretinide (4-HPR, NSC 374551) in Children With Recurrent or Resistant Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML), and Non-Hodgkin's Lymphoma (NHL) IND #70,058"""NCT01187810
Fenretinide/LXS Oral Powder Plus Ketoconazole in Recurrent Ovarian CancerPhase I/II Trial of Fenretinide/LXS Oral Powder (NSC 374551) Plus Ketoconazole in Recurrent Ovarian Cancer and Primary Peritoneal CarcinomaNCT01535157
The effects of fenretinide on insulin sensitivityA randomized double blind placebo controlled study on the effects of fenretinide Lym-X-Sorb on insulin sensitivity in obese insulin resistant subjects - The effects of fenretinide on insulin sensitivityEUCTR2011-006165-18-NL
Phase I Trial of IV Fenretinide (4-HPR) Plus IV Safingol for Patients With Relapsed MalignanciesPhase I Trial of Intravenous Fenretinide (4-HPR) Plus Intravenous Safingol for Patients With Relapsed MalignanciesNCT01553071
Het effect van fenretinide op insulinegevoeligheid.A randomized double blind placebo controlled study on the effects of fenretinide Lym-X-Sorb on insulin sensitivity in obese insulin resistant subjects.NL-OMON25232
Expanded Access Study of Fenretinide Lym-X-Sorb Plus Ketoconazole in NeuroblastomaExpanded Access Study of Fenretinide (4-HPR, NSC 374551) Lym-X-Sorb (LXS) Oral Powder Plus Ketoconazole in Patients With Recurrent or Resistant Neuroblastoma (IND#68,254)NCT02075177
Safety Study of Fenretinide in Adult Patients With Cystic FibrosisAn Adaptive Phase I Intra-patient Dose Escalation Study of Fenretinide in Adult Cystic Fibrosis PatientsNCT02141958
Trial of Intravenous Fenretinide Emulsion for Patients With Relapsed/Refractory Peripheral T-cell LymphomasPhase II Trial of Intravenous Fenretinide (N-(4-hydroxyphenyl) Retinamide, 4-HPR) Emulsion for Patients With Relapsed/Refractory Peripheral T-cell Lymphomas (PTCL)NCT02495415
Phase 1 Trial of ST-001 NanoFenretinide in Relapsed/Refractory T-cell Non-Hodgkin LymphomaA Phase 1a/1b Trial in Relapsed/Refractory T-cell Non-Hodgkin Lymphoma to Determine the Safety Profile, Pharmacology, and Maximum Tolerated Dose of ST-001, a Fenretinide Phospholipid Suspension (12.5 Mg/mL) for Intravenous InfusionNCT04234048
Fenretinide in Treating Patients With Refractory or Relapsed Hematologic CancerPhase I Trial of Intravenous Fenretinide (4-HPR) for Patients With Hematologic MalignanciesNCT00104923
Fenretinide and Lonafarnib in Treating Patients With Advanced or Recurrent Head and Neck CancerA Phase IB Randomized Translational Study of Fenretinide (4-HPR) in Combination With SCH66336, a Farnesyl Transferase Inhibitor, in Patients With Advanced or Recurrent Head and Neck CancerNCT00103090
A Study to Evaluate the Safety of Fenretinide in Healthy VolunteersA Phase 1a, Randomized, Double-blind Placebo-controlled Study to Evaluate Safety and Tolerability and to Characterize the Pharmacokinetic Profile of Single Ascending Doses of Fenretinide Oral Capsules in Healthy Adult VolunteersNCT06181760
Fenretinide in Preventing Ovarian Cancer in Participants Who Are at High Risk for Developing Ovarian Cancer and Planning to Undergo Surgery to Remove the OvariesA Multicenter Randomized Double-Blinded Trial for Chemoprevention of Ovarian Cancer: Modulation of Biomarkers and Spectral Properties Using Contrast Enhanced Ultrasound in High-Risk Women Using Fenretinide (4-HPR)NCT00098800
Hormone Therapy in Treating Postmenopausal Women With Receptor-Positive Breast CancerPHASE III DOUBLE-BLIND, PLACEBO-CONTROLLED, PROSPECTIVE RANDOMIZED COMPARISON OF ADJUVANT THERAPY WITH TAMOXIFEN VS. TAMOXIFEN AND FENRETINIDE IN POSTMENOPAUSAL WOMEN WITH INVOLVED AXILLARY LYMPH NODES AND POSITIVE RECEPTORSNCT00002646
Fenretinide in Treating Patients With Cervical NeoplasiaA Randomized Double-Blind Study of N-(4-hydroxyphenyl) Retinamide (4-HPR) Versus Placebo in Patients With Cervical Intraepithelial Neoplasia (CIN) Grade 2-3NCT00003075
Fenretinide in Treating Patients Who Have Undergone Surgery for Bladder CancerRandomized Chemoprevention Trial With 4-HPR (Fenretinide) in Superficial Bladder CancerNCT00004154
Fenretinide in Treating Patients With Leukoplakia of the MouthA Randomized, Double Blind, Placebo-Controlled Phase II Clinical Trial of N(4-Hydroxy-phenyl)Retinamide (Fenretinide, 4HPR) in Oral LeukoplakiaNCT00004161
Fenretinide in Treating Patients With Recurrent Malignant GliomaPhase II Evaluation of Fenretinide NSC (374551) as a Single Agent in the Treatment of Adult Patients With Recurrent Malignant GliomaNCT00006080
Fenretinide in Treating Patients With Recurrent or Metastatic Head and Neck CancerA Phase II Study of Fenretinide in Recurrent and Metastatic Squamous Cell Carcinoma of the Head and NeckNCT00006471
4-HPR and FTI in Head and Neck Squamous Cell Carcinoma (HNSCC)A Phase IB Randomized Translational Study of Fenretinide (4-HPR) in Combination With SCH66336, a Farnesyl Transferase Inhibitor, in Patients With Advanced or Recurrent Head and Neck CancerNCT00102635
SWOG-9507, Fenretinide in Treating Patients With Neoplasia of the MouthA Single Arm, Phase II Study to Determine the Safety and Efficacy of 4-HPRN-(4-Hydroxyphenyl) Retinamide for Treating Oral Intraepithelial NeoplasiaNCT00003223
Fenretinide in Treating Patients With Recurrent Small Cell Lung CancerPhase II Trial Of Fenretinide (NSC-374551; IND-40, 294) In Patients With Relapsed Small Cell Lung CancerNCT00009971
Chemotherapy in Treating Patients With Advanced Kidney CancerA Phase Two Study Of Fenretinide In Renal Cell CancerNCT00011973
Fenretinide Followed by Surgery Compared With Surgery Alone in Preventing Ovarian Cancer in Patients at Increased RiskAn Exploratory Evaluation of Fenretinide (4-HPR) as a Chemopreventive Agent for Ovarian CarcinomaNCT00017134
Fenretinide in Treating Patients With Recurrent or Metastatic Ovarian Epithelial or Primary Peritoneal CancerPhase II Trial of Fenretinide (NSC 374551) in Recurrent Ovarian Cancer and Primary Peritoneal CarcinomaNCT00026091
Tretinoin With or Without Fenretinide in Treating Patients With Dysplastic Nevus SyndromeA Phase II Double-Blind Study of Topical Tretinoin With or Without Oral 4-HPR (Fenretinide) in Patients With the Dysplastic Nevus SyndromeNCT00003601
Combination Chemotherapy in Treating Patients With Advanced Solid TumorsA Phase I Trial of Fenretinide in Combination With Paclitaxel and CisplatinNCT00005819
Fenretinide in Treating Children With Recurrent or Resistant NeuroblastomaA Phase II Study of Fenretinide (NSC# 374551, IND# 40294) in Children With Recurrent/Resistant High Risk NeuroblastomaNCT00053326
Neoadjuvant and Adjuvant Fenretinide Compared With Adjuvant Fenretinide Alone in Treating Patients Who Are Undergoing Surgical Resection For Recurrent Glioblastoma MultiformeA Phase II Evaluation With Correlative Studies Of Fenretinide (NSC 374551-4HPR) As A Single Agent In The Treatment Of Adult Patients With Recurrent Glioblastoma MultiformeNCT00075491
Fenretinide Lym-X-Sorb + Ketoconazole + Vincristine for Recurrent or Resistant NeuroblastomaPhase I Study of Fenretinide (4-HPR, NSC 374551) Lym-X-Sorb (LXS) Oral Powder Plus Ketoconazole Plus Vincristine in Patients With Recurrent or Resistant Neuroblastoma (IND #68,254)NCT02163356
Combination Chemotherapy in Treating Patients With Solid TumorsA Phase I Study Of Fenretinide Combined With Paclitaxel And Cisplatin For The Treatment Of Refractory Solid TumorsNCT00009932
Fenretinide In Treating Patients With Advanced or Metastatic Hormone-Refractory Prostate CancerA Phase 2 Study Of Fenretinide In Patients With Hormone Refractory Prostate CancerNCT00077402
Fenretinide in Treating Patients With Biochemically Recurrent Hormone-Naïve Prostate CancerA Phase II Trial of Fenretinide (4-HPR) in Biochemically Recurrent, Hormone Naive Prostate CancerNCT00080899
Fenretinide in Treating Children With Solid TumorsA Phase I Study of Fenretinide (NSC #374551) in Children With High Risk Solid TumorsNCT00003191
Fenretinide in Treating Patients With Solid TumorsPhase I Evaluation of Fenretinide (NSC# 374551)NCT00003250