IMPPAT Phytochemical information: 
Aescin

Aescin
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
A phase II, single-center, randomized, controlled, observer-blind study with intra-individual comparisons within two parallel groups to assess the efficacy of a topical Aescin formulation in the treatment of allergic contact dermatitisA phase II, single-center, randomized, controlled, observer-blind study with intra-individual comparisons within two parallel groups to assess the efficacy of a topical Aescin formulation in the treatment of allergic contact dermatitisEUCTR2009-009379-36-DE
The efficacy of single-dose aescin in preventing postoperative sore throat compared to placebos: a double-blinded, randomized controlled trialThe efficacy of single-dose aescin in preventing postoperative sore throat compared to placebos: a double-blinded, randomized controlled trialTCTR20190903005
The Efficacy of Aescin in Combination With MPFF in the Early Control of Bleeding From Acute Internal Hemorrhoids, A Randomized Controlled TrialThe Efficacy of Aescin in Combination With Micronized Purified Flavonoid Fraction (MPFF) in the Early Control of Bleeding From Acute Internal Hemorrhoids, A Randomized Controlled TrialNCT06363513
The Efficacy of Aescin in Combination With Micronized Purified Flavonoid Fraction (MPFF) in the Control of Bleeding and Prevent Recurrence of Acute Internal Hemorrhoids, A Randomized Controlled Trial, A Pilot StudyThe Efficacy of Aescin in Combination With Micronized Purified Flavonoid Fraction (MPFF) in the Control of Bleeding and Prevent Recurrence of Acute Internal Hemorrhoids, A Randomized Controlled Trial, A Pilot StudyNCT06748014
A phase IIa, single-center, randomized, reference-controlled, observer-blind trial to assess the efficacy of a topical Aescin formulation in experimentally induced itch, wheal and flare reactions in patients with type-I allergyA phase IIa, single-center, randomized, reference-controlled, observer-blind trial to assess the efficacy of a topical Aescin formulation in experimentally induced itch, wheal and flare reactions in patients with type-I allergyEUCTR2010-019373-15-DE
To compare the usefulness of aescin and diclofenac sodium in managing pain, swelling, mouth opening after lower third molar surgery.Comparison of the efficacy of aescin as against diclofenac sodium in the management of postoperative sequelae and their effect on salivary Prostaglandin E2 and serum C–reactive protein levels after surgical removal of impacted mandibular third molar: a randomized, double-blind, controlled clinical trial. - NILCTRI/2023/09/058004
Mechanism of Action and Clinical Translational Application of aescin in the Treatment of Helicobacter pylori-Associated Gastric UlcersMechanism of Action and Clinical Translational Application of aescin in the Treatment of Helicobacter pylori-Associated Gastric UlcersChiCTR2400080622