IMPPAT Phytochemical information: 
Glycolic acid

Glycolic acid
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
The Efficacy and Safety of a Single 70% Glycolic Acid Peel With Vitamin C for the Treatment of Acne ScarsPhase 2 Study of the The Efficacy and Safety of a Single 70% Glycolic Acid Peel With Vitamin C for the Treatment of Acne ScarsNCT02126657
Compare the efficiency of Laser treatment vs Chemical peels treatment in patients with mealsma(facial hyperpigmentation)Comparison of Modified Melasma Area and Severity Index (mMASI) scores between low fluence Q-switched Nd:YAG laser vs 35 % glycolic acid peels for melasma: A randomized controlled trialCTRI/2019/03/017943
Efficacy,tolerability and side effects of 35% Trichloroacetic acid and 50% Glycolic acid peel in Acanthosis nigricans.Efficacy,Tolerability And Side effects of 35% Trichloroacetic acid and 50% Glycolic acid peel in Acanthosis nigricans-Single Blinded Randamonized Control TrialCTRI/2019/01/017285
Acanthosis Nigricans projectA comparative study of efficacy and safety of Glycolic acid 70% peel with topical Tretinoin 0.05% in the treatment of Acanthosis Nigricans patientsIRCT20221129056666N1
To assess the outcome of 20%glycolic acid peel versus 30%lactic acid peel in treatment of periorbital melanosisTo study the therapeutic efficacy of 20 % glycolic acid peel versus 30% latic acid peel in the treatment of periorbital hyperpigmentation.CTRI/2022/09/045232
Microneedling with 70% gylcolic acid peel for treatment of atrophic acne scarsEfficacy of microneedling with 70% glycolic acid peel vs microneedling alone in treatment of atrophic acne scars- A randomised controlled trailCTRI/2014/12/005292
The Efficacy and Safety of a Single 70% Glycolic Acid Peel With Vitamin C for the Treatment of PhotoagingPhase 2 Study of the Efficacy and Safety of a Single 70% Glycolic Acid Peel With Vitamin C for the Treatment of PhotoagingNCT02126644
COMPARISON OF GLYCOLIC ACID PEEL (50%) WITH LACTIC ACID PEEL (82%) IN MELASMAComparison of Glycolic acid peel (50%) with Lactic acid peel (82%) in MelasmaCTRI/2018/06/014417
Effectiveness of glycolic acid for the treatment of the pigmented lesion; Prospective, randomized, and split-face comparative studyEffectiveness of glycolic acid for the treatment of the pigmented lesion; Prospective, randomized, and split-face comparative study - Effectiveness of glycolic acid for the treatment studyJPRN-UMIN000020247
Study to assess safety and efficacy of synthetic membrane used in limbal epithelial cell transplant instead of donor membrane in blindness caused by chemical burnsA proof of concept study to evaluate the clinical safety and efficacy of a Poly Lactide-co-Glycolic Acid (PLGA) biodegradable, synthetic carrier membrane, used to regenerate epithelium using autologous limbal tissue as a single step procedure in patients having total unilateral limbal stem cell deficiency (LSCD). - LVPEI-2012-11CTRI/2015/08/006147
Clinical and Radiographic evaluation of a synthetic bone graft gel in the surgical treatment of patients with gum diseaseClinical and radiographic evaluation of Poly Glycolic Acid / Poly Lactic Acid and hydroxyapatite paste in the treatment of periodontal intrabony defects:A randomized controlled clinical trial - NILCTRI/2024/09/074332
Safety , Efficacy and Tolerability of 35% Glycolic acid peel versus 15% Trichloroacetic acid peel in MelasmaSAFETY, EFFICACY AND TOLERABILITY OF 15% TRICHLOROACETIC ACID AND 35% GLYCOLIC ACID PEELS IN MELASMA -DOUBLE BLINDED RANDOMIZED CONTROL TRIALCTRI/2019/05/019205
Modified Jessner's Solution With Trichloroacetic Acid Versus Glycolic Acid With Trichloroacetic AcidThe Efficacy of Combined Peels in Treatment of Melasma Using Modified Jessner's Solution With 20%Trichloroacetic Acid Versus 70%Glycolic Acid With 20% Trichloroacetic Acid : A Split-face StudyNCT03153852
A Pilot Study Testing 1064nm Q-switch Laser Versus Glycolic Acid Peels for the Treatment of MelasmaA Pilot Study Comparing the Efficacy of 1064 Q-switch Laser vs. Glycolic Acid Peels for the Treatment of Melasma: A Randomized Control TrialNCT01976273
Clinical efficacy of Glycolic Acid with Fractional CO2 laser in the treatment of Primary Cutaneous AmyloidosisClinical efficacy of Glycolic Acid with Fractional CO2 laser in the treatment of Primary Cutaneous AmyloidosisChiCTR1900024771
â??COMPARATIVE STUDY OF THE THERAPEUTIC EFFICACY OF GLYCOLIC ACID PEEL AND Q-SWITCHED LASER IN MELASMAâ??â??COMPARATIVE STUDY OF THE THERAPEUTIC EFFICACY OF GLYCOLIC ACID PEEL (35%-50%) AND LOW FLUENCE (1064nm) Q-SWITCHED Nd:YAG LASER IN MELASMAâ??CTRI/2013/08/003935
Study to compare the effectiveness of 15% trichloroacetic acid peel and 35% glycolic acid peel in the treatment of acanthosis nigricansEfficacy of 15% trichloroacetic acid peel versus 35% glycolic acid peel in acanthosis nigricans - a randomized open label studyCTRI/2021/02/030952
An Open-label Study of the Safety and Pharmacokinetics of the TGKP"An Open-label Study of the Safety and Pharmacokinetics of the Glycolic Acid Tetrasubstituted Piceatannol (TGKP, ""Study Drug"") With a Single Intravenous Administration With Participation of Healthy Volunteers: 3 Arms With Dose Escalation"NCT06127381
Microneedling With Topical Preparations in the Treatment of Atrophic Post-acne ScarsMicroneedling With Topical Glycolic Acid 35% Versus Microneedling With Topical Insulin in the Treatment of Atrophic Post-acne ScarsNCT05600075
Acquired Epidermodysplasia Verruciformis (EV) Syndrome in HIV-infected Pediatric PatientsAcquired Epidermodysplasia Verruciformis (EV) Syndrome in HIV-infected Pediatric Patients: Prospective Treatment Trial With Topical Glycolic Acid and HPV Genotype CharacterizationNCT01289171
comparison of chemical peel versus tranexamic acid tablet for treatment of facial pigmentationA determine the safety and efficacy of glycolic acid peel versus oral tranexamic acid in management of melasmaCTRI/2022/07/044452
Comparison of Dermaroller versus Dermaroller with topical PRP versus glycolic acid chemical peels in melasmaComparative study of efficacy and safety of microneedling versus combination of microneedling and topical autologous platelet rich plasma versus 30% glycolic acid peels in melasmaCTRI/2021/03/031705
The effect of glycolic acid peeling for acne vulgaris: a double-blind, randomized, left-right comparison studyThe effect of glycolic acid peeling for acne vulgaris: a double-blind, randomized, left-right comparison study - The effect of GA peeling for acne vulgarisJPRN-UMIN000004376
Efficacy and safety of 5% glycolic acid-based gel essence in the treatment of mild to moderate acneEfficacy and safety of 5% glycolic acid-based gel essence in the treatment of mild to moderate acneChiCTR2100054179
Comparison of Chemical Peeling Agent With Transamine for Treatment of MelasmaComparative Study Between Chemical Peeling With 70% Glycolic Acid and Intradermal Transamine for the Treatment of Melasma.NCT05362500
TCA 15% Chemical Peel for Improvement in Hand LentiginesUse of TCA 15% + 3% Glycolic Acid Chemical Peel for Improvement in Hand LentiginesNCT05471947
Comparison of use of glycolic acid and salicylic acid peel in acne(pimples).Comparative efficacy of glycolic acid 35% vs salicylic acid 20% peel in acne vulgaris.CTRI/2018/06/014615
Study about the treatment of pre-cancer skin lesionsStudy on 70% glycolic acid peeling associated with 5-fluorouracil 5% compared to the topical use of 5-fluorouracil 5% cream in the treatment of actinic keratosIs: a non-randomized clinical trialRBR-78mj2c
Effect of application of cream with skin peeling compared to cream alone in patients of facial pigmentation.Effect of Glycolic Acid (GA) peel as an adjuvant with triple combination(TC-Modified Kligmanâ??s formula) versus triple combination (TC-Modified Kligmanâ??s formula) alone in patients of melasma in Department of Dermatology, GMERS Medical College, Gotri, Vadodara.CTRI/2019/07/020372
A study of comparison of efficacy of 80% Lactic acid peel with 50% Glycolic acid for the treatment of melasmaA comparative study of 80% Lactic acid peel vs 50% Glycolic acid peel in the treatment of melasmaCTRI/2023/01/049069
Comparative study for salicylic acid vs glycolic acid in the treatment of mild-to-moderate acne vulgarisComparative study for salicylic acid vs glycolic acid in the treatment of mild-to-moderate acne vulgaris: a prospective, randomized, split-face trialChiCTR1800018343
A clinical trial to study the effects of 1064 nm Q Switched Nd-YAG laser and glycolic acid peel in patients with macular amyloidosisA comparative study on the efficacy and dermoscopic changes in 1064 nm Q Switched Nd-YAG laser versus glycolic acid peel in Macular Amyloidosis - NilCTRI/2024/05/066757
A Pilot Study Testing Salicylic Acid Peels Versus Glycolic Acid Peels for the Treatment of MelasmaA Pilot Study Comparing the Efficacy of Glycolic Acid Peels Vs. Salicylic Acid Peels for the Treatment of Melasma: a Randomized Control TrialNCT01976286
To evaluate safety and benefit of Ahaglow (GlycOlic acid, Aloe veRa and Vitamin-E) based face wash for daily use in Acne Prone SkinA Patient Reported Outcome Study to Assess Clinical Impact, Utilization and Safety of Glycolic Acid, Aloe VeRA and Vitamin - E based face wash for daily use in Acne Prone Skin (AUORA)CTRI/2023/06/053763
Comparing the effectiveness of two chemical peels , 15% Trichloroacetic acid peel versus 35% Glycolic acid peel in the treatment of Melasma.Comparative study of 15% Trichloroacetic acid peel versus 35% Glycolic acid peel for their effectiveness over Melasma. - NILCTRI/2025/01/079337
Effect of 17% Glycolic Acid in Primary Endodontic Treatment: Randomized Clinical TrialEffect of 17% Glycolic Acid on Periapical Healing in Primary Endodontic Treatment: Randomized Clinical TrialRBR-44q9k6q
Safety and Efficacy of Merlin (Ethanol and Glycolic Acid Mixture) for Episodic Treatment of Cold SoresA Multicenter, Placebo-Controlled, Randomized, Double-Blind Study of the Safety and Efficacy of Merlin (Ethanol and Glycolic Acid Mixture) for the Episodic Treatment of Recurrent Herpes LabialisNCT03192306
A comparison of trichloroacetic acid and glycolic acid chemical peels in the treatment of melasmaA comparative study of trichloroacetic acid and glycolic acid chemical peels in the treatment of melasma: a spilt face study - NilCTRI/2023/10/058852
Boosting Fungal Infection Treatment with Chemical Peels: A New ApproachEfficacy of Weekly 50% Glycolic Acid Peel in Combination with Oral and Topical Antifungals in the Treatment of Dermatophytosis: A Pilot StudyCTRI/2025/04/084857
comparison of 2 chemical peels in treatment of facial pigmentationdetermine the safety and efficacy of mandelic acid peel versus glycolic acid in management of melasmaCTRI/2022/07/044512
To compare two different percentage of glycolic acid chemical peel in the treatment of periorbital hyperpigmentationComparison of 35% and 20% Glycolic acid peel in the treatment OfPeriorbital hyperpigmentation - nilCTRI/2024/02/062648
COMPARATIVE STUDY OF THE EFFICACY AND SAFETY OF 10% RETINOL PEEL AND 70% GLYCOLIC ACID PEEL IN THE TREATMENT OF ACANTHOSIS NIGRICANSAn observational study of the efficacy and safety comparing 10% Retinol peel and 70% Glycolic acid peel in the treatment of Acanthosis NigricansCTRI/2023/09/057674
"""Comparing laser and chemical treatments for neck dark spots"""A split-neck interventional study to compare the efficacy of Ablative Fractional CO2 laser vs 70% Glycolic acid peel in Acanthosis nigricans - NILCTRI/2024/05/066976
A New Skin Peel Treatment Combining Tranexamic Acid, Glycolic Acid, and Vitamin C to Improve MelasmaA Novel Triple Combination (Tranexamic Acid, Glycolic Acid, and Vitamin C) Chemical Peel for Melasma - NILCTRI/2024/12/078352
Comparative Study of Therapeutic Efficacy and Safety of Glycolic Acid 6% and Azelaic Acid 20% in MelasmaPROSPECTIVE RANDOMIZED COMPARATIVE STUDY OF THERAPEUTIC EFFICACY AND SAFETY OF GLYCOLIC ACID 6% AND AZELAIC ACID 20% IN MELASMACTRI/2021/06/034044
Treatment of Acne scarsA comparative study on the efficacy of glycolic acid v/s azelaic acid in the treatment of post acne hyperpigmentation - PIHCTRI/2018/02/012050
TO CALCULATE THE QUALITY OF 50% GLYCOLIC ACID PEEL WITH 30% TRICHLOROACEDIC ACID PEEL IN PATIENT WITH ACANTHOSIS NIGRICANS.Intervention study.Outcome of the study: Evaluate the efficacy of peeling agents.To analyse the side effects of the peeling agent.Evaluate The Efficacy Of 50% Glycolic Acid Peel With 30% Trichloroacedic Acid Peel In Acanthosis Nigricans In a Tertiary Care Centre,Tamil Nadu. - NILCTRI/2024/05/067735
Comparing outcome between oral tranexamic acid 250mg with 35 percent Glycolic acid peels versus oral tranexamic acid with low fluency q switched nd-yag laserComparative efficacy and safety of Oral Tranexamic acid with 35 percent Glycolic acid peels and Oral Tranexamic acid with low Fluence Q Switched ND-YAG Laser in treatment of Melasma. - NILCTRI/2024/06/069086
To know the bettertreatment for melasma skin disease intralesional tranexamic acid or glycolic acid chemical peelA comparative study on safety and efficacy of intralesional tranexamic acid versus 50% glycolic acid chemical peel in the treatment of melasmaCTRI/2023/09/057178
It is a comparative study of two groups. In study group advanced bioabsorbable material (PLGA) is used to reconstruct the orbital floor fracture and in controlled group traditional Titanium plate, mesh and screw are used. Then comparison will be done and outcomes will be accessedComparative evaluation of functional and esthetic outcome of orbital floor reconstruction using poly Lactic co-glycolic acid mesh and titanium mesh in patient with orbital floor fracture- Randomized control trial. - NILCTRI/2024/10/075829
Glycolic Acid Plus Salicylic Acid in Treatment of Plane WartEfficacy of Glycolic Acid 15%Plus Salicylic Acid 2% Gel in Treatment of Plane WartNCT06233019
CHEMICAL PEELS FOR MACULAR AMYLOIDOSIS: A STUDY OF 15% TRICHLOROACETIC ACID PEEL VERSUS 35% GLYCOLIC ACID PEEL.A RANDOMISED CONTROL STUDY TO EVALUATE THE EFFICACY AND SAFETY OF 15% TRICHLOROACETIC ACID PEEL VERSUS 35% GLYCOLIC ACID PEEL IN PATIENTS WITH CUTANEOUS MACULAR AMYLOIDOSIS. - NILCTRI/2025/03/082200
Treatment of Melasma With Glycolic Acid-Salicylic Acid Peel Versus Glycolic Acid PeelComparing the Efficacy and Safety of Combined Glycolic Acid and Salicylic Acid Peel Versus Glycolic Acid Peel Alone in the Treatment of Melasma: A Split Face StudyNCT02812719
Safety and Efficacy of Merlin (Ethanol and Glycolic Acid Mixture) for the Treatment of Cold SoresA Multicenter, Placebo-Controlled, Randomized, Double-Blind Study of the Safety and Efficacy of Merlin (Ethanol and Glycolic Acid Mixture) for the Episodic Treatment of Recurrent Herpes LabialisNCT01985321