IMPPAT Phytochemical information: 
Lutein

Lutein
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
A multi-center, randomized, parallel-group study to assess the changes in macular pigment density and visual performance in the patients with age-related macular degeneration, who received a lutein supplementA multi-center, randomized, parallel-group study to assess the changes in macular pigment density and visual performance in the patients with age-related macular degeneration, who received a lutein supplement - A multi-center study to assess the macular pigment density and visual performance in age-related macular degenerationJPRN-UMIN000007628
Preventive effect of lutein treatment on angiographic macula edema after cataract surgeryPreventive effect of lutein treatment on angiographic macula edema after cataract surgery - Preventive effect of lutein on macula edema after cataract surgeryJPRN-UMIN000000938
Effects of dual-task exercise combined with mouth rinse and paprika xanthophyll ingestion on cognitive functionEffects of dual-task exercise combined with mouth rinse and paprika xanthophyll ingestion on cognitive function - Effects of dual-task exercise combined with mouth rinse and paprika xanthophyll ingestion on cognitive functionJPRN-UMIN000054104
To assess the Safety and Effectiveness of Supplementation of Lutein Formulations on Improving Macular Pigment Optical DensityA Prospective, Randomized, Double-Blind, Placebo Controlled Study to Evaluate the Safety & Efficacy of Supplementation of Lutein Formulations on Improving Macular Pigment Optical Density in Healthy Adults - NilCTRI/2023/11/060356
Clinical trial on eye healthA Randomized, double-blind, three arm, placebo-controlled clinical study to evaluate the modulatory effect of Lutein and Zeaxanthin supplementation (Gleamax / Vividawn) on MPOD levels along with Glare disability and Contrast enhancement in healthy subjects. - NILCTRI/2023/12/060711
Clinical and Radiographic Assessment of PRF Versus Lutein PlacementClinical and Radiographic Assessment of PRF Versus Lutein Placement Around Immediately Placed Dental ImplantsNCT06358352
Long Term Effects of Lutein/Zeaxanthin and Omega-3- Supplementation on Optical Density of AMD Patients (LUTEGA)Long Term Effects of Lutein/Zeaxanthin and Omega-3- Supplementation on Optical Density of AMD Patients (LUTEGA)NCT00763659
Long Term Effects of Lutein/Zeaxanthin and Omega-3- Supplementation for Two More Years (LUTEGA 2)Long Term Effects of Lutein/Zeaxanthin and Omega-3- Supplementation on Optical Density of AMD Patients for Two More Years (LUTEGA 2)NCT01648660
Effects of dietary supplementation containing lutein, zeaxanthin, and omega-3 polyunsaturated fatty on the serum carotenoids and fatty acids concentrations, macular pigment and visual function in people with long-term computer display light exposureEffects of dietary supplementation containing lutein, zeaxanthin, and omega-3 polyunsaturated fatty on the serum carotenoids and fatty acids concentrations, macular pigment and visual function in people with long-term computer display light exposureTCTR20220904002
Effects of Lutein on Visual FunctionBeneficial Effects of Lutein on Visual Function in Healthy SubjectsNCT03113864
A study for the effects of ingestion of food containing plant extract and lutein on visual function.:A randomized, double-blind, placebo controlled trialA study for the effects of ingestion of food containing plant extract and lutein on visual function.:A randomized, double-blind, placebo controlled trial - A study for the effects of ingestion of food containing plant extract and lutein on visual function.JPRN-UMIN000024336
Evaluation of Antioxidant Activity of Oral Lutein in Preterm and Term NewbornEvaluation of Antioxidant Activity of Oral Lutein in Preterm and Term NewbornNCT02068807
Intake of lutein-rich spinach and biomarkers; a pilot studyIntake of lutein-rich spinach and biomarkers; a pilot study - Spinach studyJPRN-UMIN000014106
Dietary Lutein and the Retinopathy of PrematurityThe Placental and Mammary Transfer of Lutein and Zeaxanthin Into the Fetus and the Breast-fed InfantNCT00672230
Safety evaluation of an excessive consumption of Bilberry extract and LuteinSafety evaluation of an excessive consumption of Bilberry extract and Lutein - Safety evaluation of an excessive consumption of Bilberry extract and LuteinJPRN-UMIN000025414
The Effects of Lutein and Zeaxanthin Supplementation on Vision in Patients With AlbinismA Randomized Placebo-controlled Trial to Investigate the Effect of Lutein and Zeaxanthin Supplementation on Macular Pigment and Visual Function in Albinism - LUtein for VIsion in Albinism (LUVIA)NCT02200263
Evaluation of the Benefits of FloraGLO™ Lutein on Skin HealthA 12-Week, Randomized, Double-Blind, Placebo-Controlled Evaluation of the Benefits of FloraGLO™ Lutein on Skin HealthNCT03769779
The effect of lutein supplementation on macular pigment density in patients who have undergone cataract surgeryProspective, open, pilot study of oral supplementation with lutein in patients having undergone cataract surgery: effect on macular pigment densityISRCTN71306406
A study to assess the effect of Lutein & Zeaxanthin on Visual improvement among thehealthy subjectsA Double-Blind, Placebo-Controlled Trial on the Effects of Lutein and Zeaxanthinon Macular pigment optical density response, Photo stress Recovery, GlareDisability, and Chromatic Contrast - NilCTRI/2023/08/057023
Effects of lutein/ zeaxanthin on eye health, eye strain, sleep quality, and attention in high electronic screen usersEffects of lutein/ zeaxanthin on eye health, eye strain, sleep quality, and attention in high electronic screen users: a randomised, double-blind, placebo-controlled studyACTRN12623000427673
Effects of Lutein Supplementation on Subclinical AtherosclerosisThe Effects of Lutein Supplementation on Subclinical AtherosclerosisNCT01534533
The effect of the dietary antioxidant supplements lutein and zeaxanthin on retinal macular pigment optical densityMacular pigment response to supplemental lutein and zeaxanthin: a twin heritability studyISRCTN55089134
A prospective, randomized, double blind study comparing lutein to placebo for reducing occurrence and severity of retinopathy of prematurity, and evaluating antioxidative power and central visual function.A prospective, randomized, double blind study comparing lutein to placebo for reducing occurrence and severity of retinopathy of prematurity, and evaluating antioxidative power and central visual function. - Lutein supplementation in preterm infants. A RCT.JPRN-UMIN000007041
Effects of Lutein and Zeaxanthin Supplementation on Early Age-related Macular DegenerationThe Effects of Lutein and Zeaxanthin Supplementations on Early Age-related Macular DegenerationNCT01528605
Macular Pigment Density Evolution in Unilateral Wet AMD Versus Non AMD Patients With or Without Lutein and Zeaxanthine SupplementationAssessment of the Evolution of Macular Pigment Density in Two Distinct Populations, Before and After Supplementation With Nutrof Total Versus Dietary Supplement Without Lutein and Zeaxanthin, Using the Macular Pigment Module of Visucam 200 or Visucam 500 (Zeiss).NCT01404845
Lutein Bioavailability From Fresh and Dried BeveragesBioavailability of Lutein From a Lutein-enriched Egg-yolk-beverage and Its Dried Re-suspended Versions.NCT01400763
Effectiveness for macular pigment with lutein supplementation in central serous chorioretinopathyEffectiveness for macular pigment with lutein supplementation in central serous chorioretinopathy - Effectiveness for macular pigment with lutein supplementation in central serous chorioretinopathyJPRN-UMIN000005849
Lutein and zeaxanthin supplementation in preterm infants to prevent retinopathy of prematurityLUtein and zeaxanthin SUpplementation in Preterm infants to prevent RetinOpathy of Prematurity: a multicentre prospective randomised double-blind placebo-controlled studyISRCTN10624844
Bioavailability of lutein from potatoes -a pilot study.Bioavailability of lutein from potatoes -a pilot study. - Bioavailability luteinNL-OMON37412
Bioavailability of lutein from a lutein-enriched egg-yolk-beverage and its dried re-suspended versions.Bioavailability of lutein from a lutein-enriched egg-yolk-beverage and its dried re-suspended versions. - Lutein bioavailability from fresh and dried beveragesNL-OMON35978
The clinical study for the effect of oral supplementary drugs containing lutein on macular pigment densityThe clinical study for the effect of oral supplementary drugs containing lutein on macular pigment density - The effect of oral supplementary drug containing lutein on macular pigment densityJPRN-UMIN000011512
The effects of 2 types of lutein supplements on macular pigment and visual functionsThe effects of 2 types of lutein supplements on macular pigment and visual functions - Macular pigment and visual functionsJPRN-UMIN000004593
Effects of buttermilk with or without lutein-enriched egg yolk on the serum LDL-cholesterol concentration of slightly hypercholesterolemic volunteersEffects of buttermilk with or without lutein-enriched egg yolk on the serum LDL-cholesterol concentration of slightly hypercholesterolemic volunteers - buttermilk and cholesterolNL-OMON38303
Levels of Macular Pigment Optical Density Responses to Supplementation with Different Levels of Lycium Barbarum and Lutein in Patients with High Myopia of Different CategoriesLevels of Macular Pigment Optical Density Responses to Supplementation with Different Levels of Lycium Barbarum and Lutein in Patients with High Myopia of Different CategoriesChiCTR2100046748
Efficacy of Lutein, Zeaxanthine and Trypan Blue to Stain the Anterior Lens CapsuleA Descriptive Study to Evaluate the Efficacy of the Dye Compound of the Combination of Lutein, Zeaxanthin and Trypan Blue to Stain the Anterior Lens Capsule During Cataract Phacoemulsification.NCT01621789
Effects of Lutein and Zeaxanthin Supplementation on Age-related Macular DegenerationEffects of Lutein and Zeaxanthin Supplementation on Age-related Macular DegenerationNCT01048476
The Influence of Lutein Supplements on Age-related Macular DegenerationThe Influence of Lutein Supplements on Age-related Macular DegenerationNCT01042860
Association of Lutein, Zeaxanthin and Brilliant Blue in ChromovitrectomyA Descriptive Study to Evaluate the Effectiveness of the Dye Compound of the Combination of Lutein, Zeaxanthin and Brilliant Blue in ChromovitrectomyNCT01627977
Effect of lutein with milk on physical activityEfficacy of lutein-milk for improving exercise self-efficacy and exercise participation in older adultsACTRN12611000248965
Randomized, three-group, parallel comparative study on changes in macular pigment optical density and visual function due to administration of supplements containing lutein and omega3 fatty acids to patients with age-related macular degeneration (patients treated with ranibizumab)Randomized, three-group, parallel comparative study on changes in macular pigment optical density and visual function due to administration of supplements containing lutein and omega3 fatty acids to patients with age-related macular degeneration (patients treated with ranibizumab) - The comparative study on the effects of lutein and omega3 fatty acids supplements to age-related macular degenerationJPRN-UMIN000004804
Single center, randomized, double-blind, placebo-controlled clinical trial of lutein, zinc gluconate and vitamin A soft capsules for eye protection in patients with type II diabetesSingle center, randomized, double-blind, placebo-controlled clinical trial of lutein, zinc gluconate and vitamin A soft capsules for eye protection in patients with type II diabetesChiCTR2500095624
macular pigment optical density in Japanese age-related macular degeneration and the effect of lutein intakemacular pigment optical density in Japanese age-related macular degeneration and the effect of lutein intake - macular pigment density in JapaneseJPRN-UMIN000001320
Improving Skin Health in Healthy Male or Female Volunteers.A Randomized, Double Blind, Placebo Controlled, Three Arm Clinical Study to Evaluate the Safety and Efficacy of Lutein Extract in Improving Skin Health in Healthy Male or Female Volunteers. - NILCTRI/2025/05/087675
Lutein and Alzheimer's Disease StudyLutein and Oxidative Stress in Alzheimer's Disease - A Pilot StudyNCT00596024
Eye Health Clinical study.A Double-Blind, Placebo-Controlled Trial on the Effects of Lutein and Zeaxanthin on Macular pigment optical density response, Photo stress Recovery, Glare Disability, and Contrast Sensitivity. - NILCTRI/2025/05/086293
The influence of oral lutein supplementation on visual function and eye health in healthy school-aged childrenThe influence of oral lutein supplementation on visual function and eye health in healthy school-aged childrenChiCTR2500100376
Clinical trail on Eye health with Keratoconjunctivitis SiccaA Randomized, Double-Blind, two-arm, placebo-Controlled Study to Evaluate the Efficacy and Safety of Lutein 10mg, Meso zeaxanthin 10mg with Zeaxanthin 2mg in Subjects with Keratoconjunctivitis Sicca. - NILCTRI/2025/03/083269
Pharmacokinetics of A soft capsules of lutein zinc gluconate and vitamin in healthy Chinese subjectsPharmacokinetics of A soft capsules of lutein zinc gluconate and vitamin in healthy Chinese subjectsChiCTR2500097526
Effect of Lutein-enriched-egg Beverage on Age-Related Macular Degeneration (AMD)The Effect of Lutein-enriched-egg Beverage on Progression of Age-related Macular Degeneration, a Randomized TrialNCT00902408
Clinical trial on Lutein and Zeaxanthin Supplementation on Eye Health in Elderly AdultsA randomized, double blind, placebo controlled, parallel study to evaluate the comparative efficacy of XanMax(R) 2004 (10mg and 20mg Lutein and Zeaxanthin) oral soft gel capsule with that of a placebo soft gel capsule in improving MPOD levels in elderly volunteers. - NILCTRI/2024/12/078490
Study of lutein (ester) metabolism and absorption by humansStudy of lutein (ester) metabolism and absorption by humansChiCTR2400094299
Early Administration of the Lutein/Zeaxanthin in Premature NewbornsEvaluation of the Antioxidant Activity of Lutein/Zeaxanthin Early Administered to Premature NewbornsNCT03340103
Lutein and Zeaxanthin Clinical trial on Eye healthA Randomized, double-blind, placebo-controlled clinical study to evaluate the modulatory effect of Lutein and Zeaxanthin supplementation on Macular Pigment Optical Density (MPOD), Glare disability and photo stress in healthy subjects. - NILCTRI/2024/09/074298
Efficacy of lutein supplement on macular pigments density and visual performance of age-related macular degeneration (AMD) patientsEfficacy of lutein supplement on macular pigments density and visual performance of age-related macular degeneration (AMD) patients - Efficacy of lutein supplement on age-related macular degenerationJPRN-UMIN000000635
Clinical Trial on Early-Stage Memory Loss (mild cognitive impairment) in Adults Aged 50-70 YearsA randomized, double-blind, placebo controlled, parallel group clinical study for the comparative evaluation of efficacy and tolerability of lutein and zeaxanthin (XanMax2002) in adult subjects with mild cognitive impairment (MCI) - NILCTRI/2024/07/071190
Clinical Trial of Lutein for Patients With Retinitis Pigmentosa Receiving Vitamin ARandomized Clinical Trial for Retinitis PigmentosaNCT00346333
Age-Related Eye Disease Study 2 (AREDS2)Age-Related Eye Disease Study 2 (AREDS2): A Multi-center, Randomized Trial of Lutein, Zeaxanthin and Omega-3 Long-Chain Polyunsaturated Fatty Acids (Docosahexaenoic Acid [DHA] and Eicosapentaenoic Acid [EPA]) in Age-Related Macular DegenerationNCT00345176
The randomized duble blind parallel-group comparison test of the effect for eye function of the Bilberry extract and LuteinThe randomized duble blind parallel-group comparison test of the effect for eye function of the Bilberry extract and Lutein - The randomized duble blind parallel-group comparison test of the effect for eye function of the Bilberry extract and LuteinJPRN-UMIN000028736
Effect of Lutein in S-26 Gold On Growth And SafetyEffect of Lutein in S-26 Gold on Growth and SafetyNCT00913406
Lutein, Zeaxathin, and Fish Oil SupplementationThe Role of Lutein, Zeaxanthin, and Fish Oil on Cognitive Function and Bone Health in Healthy AdultsNCT06489873
Effect of Lutemax 2020 on visual and brain health markersLutein and Mental Acuity Study II: an assessment of lutein and systemic factors that impact cognitive functionISRCTN17604865
The putative beneficial effects of supplemental Lutein (L) and Zeaxanthin (Z) with co-antioxidants in patients with age-related maculopathy: A pilot short term randomised controlled clinical trial of antioxidant supplementationISRCTN94557601
Macular Pigment and Glare DisabilityEffects of Lutein and Zeaxanthin Upon MPOD and Its Effects Upon Glare Disability, Photostress Recovery, and Contrast Enhancement in Healthy Subjects: A Randomized, Double-blind Placebo-controlled StudyNCT00909090
Comparing the Lutein formulations - Product A and Product B (Lutein 25 mg/capsule) supplementation in healthy, adult humans, after receiving high-fat, high-calorie breakfast.A double blind, balanced, randomized, two-treatment, single-period, single-dose, parallel, comparative bioavailability study of Lutein formulations - Product A and Product B (Lutein 25 mg/capsule) supplementation in healthy, adult human subjects under fed conditions. - N/APCTRI/2018/01/011167
A comparative randomised double blind study to evaluate the effect of Lutein supplementation on Macular Pigment Optical Density (MPOD) and blood Lutein levels in healthy adults over 16 weeks.A comparative randomised double blind study to evaluate the effect of Lutein supplementation on Macular Pigment Optical Density (MPOD) and blood Lutein levels in healthy adults over 16 weeks.ACTRN12618000276257
Exploratory test on oxidative stress in tears by intake of lutein coffeeExploratory test on oxidative stress in tears by intake of lutein coffee - Exploratory test on oxidative stress in tears by intake of lutein coffeeJPRN-UMIN000028220
Effect of paprika xanthophyll supplementation on cognitive improvement by multitask exercise: A Pilot study for middle-aged and older adultsIngestion of paprika xanthophyll supplement further enhances cognitive function improvement effect of transient multitasking exercise - Ingestion of paprika xanthophyll supplement further enhances cognitive function improvement effect of transient multitasking exerciseJPRN-UMIN000046785
The effectiveness of lutein in high myopic patientsThe effectiveness of lutein in high myopic patients - Lutein and high myopiaJPRN-UMIN000025635
Lutein Absorption in Healthy AdultsLutein Absorption in Healthy AdultsNCT01730898
The Zeaxanthin and Visual Function StudyRandomized, Double Blind, Lutein Controlled Study of Zeaxanthin and Visual Function in Atrophic Age Related Macular Degeneration PatientsNCT00564902
Clinical Trial for Nutrilite Vision Health ProductThe Effect of Botanical Formula Containing Lutein Ester and Zeaxanthin on Adults with Eye Fatigue in a Double-Blinded, Placebo-Controlled StudyChiCTR1800018987
A randomized, placebo-controlled, double-blind, parallel-group trial of the improvement in ocular function with continued lutein intakeA randomized, placebo-controlled, double-blind, parallel-group trial of the improvement in ocular function with continued lutein intake - A randomized, placebo-controlled, double-blind, parallel-group trial of the improvement in ocular function with continued lutein intakeJPRN-UMIN000033854
Effects of lutein supplementation on insulin sensitivity in participants with central obesity: a randomized controlled trialEffects of lutein supplementation on insulin sensitivity in participants with central obesity: a randomized controlled trialChiCTR1800018098
To estimate the rate and extent of absorption (bioavailability) of Lutein formulation - Product E (Lutein 20 mg/capsule) supplementation, in healthy, adult human subjects under fed conditions.A single-period, single-dose, oral bioavailability study of Lutein formulation - Product E (Lutein 20 mg/capsule) supplementation in healthy, adult human subjects under fed conditions.CTRI/2018/08/015528
Rheohemapheresis and Lutein Supplementation (xantophyll carotenoid) in the Non-Exsudative Form of Age-Related Macular Degeneration. (ReLux-AMD) - ReLux-AMDRheohemapheresis and Lutein Supplementation (xantophyll carotenoid) in the Non-Exsudative Form of Age-Related Macular Degeneration. (ReLux-AMD) - ReLux-AMDEUCTR2006-001385-16-AT
Comparative bioavailability/ bioequivalence study of Lutein formulations - Product A and Product B (Lutein 20 mg/capsule) supplementation in healthy, adult humans, after receiving high-fat, high-calorie breakfast.A double blind, balanced, randomized, two-treatment, single-period, single-dose, parallel, bioavailability/bioequivalence study of Lutein formulations - Product A and Product B (Lutein 20 mg/capsule) supplementation in healthy, adult human subjects under fed conditions. - N/APCTRI/2018/08/015507
Lutein supplementation in very low birth weight (VLBW) neonates in neonatal intensive care units (NICU)Lutein supplementation in VLBW neonates in NICU: a double-blind, multicentre, placebo-controlled, randomised trialISRCTN29971311
Comparative bioavailability/ bioequivalence study of Lutein formulations - Product C and Product D (Lutein 20 mg/capsule) supplementation in healthy, adult humans, after receiving high-fat, high-calorie breakfast.A double blind, balanced, randomized, two-treatment, single-period, single-dose, parallel, bioavailability/bioequivalence study of Lutein formulations - Product C and Product D (Lutein 20 mg/capsule) supplementation in healthy, adult human subjects under fed conditions. - N/APCTRI/2018/08/015403
Lutein for Age-Related Macular DegenerationDose Ranging Study of Lutein Supplementation in Persons Over Age 60NCT00006202
Effects of Lutein in Retinitis PigmentosaEffects of Lutein in Retinitis PigmentosaNCT00029289
The effect of a lutein based nutritional supplement on non-exudative age-related macular degeneration (AMD): a double-masked randomised controlled trialThe effect of a lutein based nutritional supplement on non-exudative age-related macular degeneration (AMD): a double-masked randomised controlled trialISRCTN78467674
Bioavailability study of lutein from ChlorellaBioavailability study of lutein from Chlorella in healthy adults.KCT0000750
Effects of lutein and omega-3 fat enriched egg consumption on visual function in older adults: Implications for age-related macular degenerationEffects of lutein and docosahexaenoic acid enriched egg consumption in older adults: Implications for age-related macular degenerationISRCTN45308629
The effect of supplement containing lutein on macular pigment optical density and visual performanceThe effect of supplement containing lutein on macular pigment optical density and visual performance - The effect of lutein supplementJPRN-UMIN000031870
Effect of Lutein, Zeaxanthin supplements on human.Effect of Lutein, Zeaxanthin supplements on human. - Lutein Zeaxanthin clinical trialJPRN-UMIN000025699
Randomized parallel-group trial of lutein supplementation for macular pigment optical density and visual function in the patients with unilateral age-related macular degenerationRandomized parallel-group trial of lutein supplementation for macular pigment optical density and visual function in the patients with unilateral age-related macular degeneration - Randomized parallel-group trial of lutein supplementation in AMDJPRN-UMIN000027962
Effect of Micronutrient Supplementation on the Intestinal Microbiota in Patients With Age-related Macular Degeneration - The Gut-Retina-axis Study": Effect of Supplementation With Lutein, Zeaxanthin and Saffron on the Intestinal Microbiota in Patients Suffering From Age-related Macular Degeneration - The Gut-Retina-axis Study"""NCT06391411
Effects of a combined Vitamin D, Omega 3, Co-enzyme Q10, Zeaxanthin, Lutein and Astaxanthin supplement (Lester’s Oil) on Healthy peopleEffects of a combined Vitamin D, Omega 3, Co-enzyme Q10, Zeaxanthin, Lutein and Astaxanthin supplement (Lester’s Oil) on Healthy peopleACTRN12616001316493
Effects of Sea Buckthorn Oil and Lutein on Eye HealthNCT02379169
Effects of Lutein Supplementation on Oxidative Stress and Inflammation in Healthy NonsmokersEffects of Lutein Supplementation on Oxidative Stress and Inflammation in Healthy NonsmokersNCT01056094
Lutein/Zeaxanthin and Omega-3 Supplementation in Persons Over Age 60Lutein/Zeaxanthin and Omega-3 Supplementation in Persons Over Age 60NCT00121589
Lutein Supplementation in Healthy ChildrenEffects of Lutein Supplementation on Cognition and Vision in Healthy Children With Screen Time Exposure: A Randomized Controlled TrialNCT05314647
The effect of lutein on cardiovascular risk factorsThe effect of lutein supplementation on anthropometric parameters, metabolic and inflammatory status, sirtuin1 and plasminogen activator inhibitor-1 in obese individuals on a low-calorie dietIRCT20191109045382N1
The efficacy of different nutritional formulas of lutein, zeaxanthin, and meso-zeaxanthin and their impact on the human bodyThe impact of formulation on lutein, zeaxanthin, and meso-zeaxanthin bioavailability: a randomized double-blind placebo-controlled studyISRCTN18206561
To Evaluate Efficacy of Lutemax 2020 (Lutein 10 mg & Zeaxanthin Isomers 2 mg) on Vision and Cognitive Performance in Healthy Children.A Prospective, Randomized, Double-Blind, Parallel, Placebo- Controlled Study to Evaluate Efficacy of Lutemax 2020 (Lutein 10 mg & Zeaxanthin Isomers 2 mg) on Vision and Cognitive Performance in Children.CTRI/2022/05/042364
A randomized, double-blind, placebo-controlled study to investigate the effects of OmniActive Lutemax 2020® oil suspension on skin health attributesThe effects of oral supplementation of lutein and zeaxanthin isomers (Lutemax2020®) on skin color and skin tone: a double-blind and placebo-controlled clinical trialISRCTN15646478
Effect of food containing water chestnut peel extract/lutein on changes in fingertip skin-measured advanced glycation endproducts/carotenoid levelsEffect of food containing water chestnut peel extract/lutein on changes in fingertip skin-measured advanced glycation endproducts/carotenoid levels - Effect of food containing water chestnut peel extract/lutein on changes in fingertip skin-measured advanced glycation endproducts/carotenoid levelsJPRN-UMIN000041756
Effects of Lutein on Learning and Memory in Chronically Stressed Subjects and in an Acute Stressful Situation (TSST - Trier Social Stress Test): A Randomized, Double-blind, Placebo-controlled Trial)Effects of Lutein on Learning and Memory in Chronically Stressed Subjects and in an Acute Stressful Situation (TSST - Trier Social Stress Test): A Randomized, Double-blind, Placebo-controlled TrialNCT02257801
A multi-site trial of a novel nutritional supplement (taurine, omega-3 fatty acids, zinc, antioxidants, and lutein) and micro-current stimulation in the treatment of atrophic (dry) age-related macular degenerationISRCTN57556290
Do omega-3 fatty acids affect the absorption of lutein and zeaxanthin in humans?Effect of omega-3-fatty acid addition to lutein and zeaxanthin supplement and their bioavailability in humansACTRN12622000837729
Using lutein-fortified yoghurt as a vehicle to deliver lutein to humans – a bioavailability studyFortification with Xanthophylls trialISRCTN45322893
Intervention Trial in Early Age-related Macular DegenerationIntervention Study to Assess the Effect of Daily Consumption of a Lutein-enriched-egg Beverage on Maintenance of Visual Function in Subjects With Early Signs of Age-related Macular DegenerationNCT01694680
Lutein and high myopiaThe effectiveness of lutein in high myopic patients - The effectiveness of lutein in high myopic patientsJPRN-jRCTs031180168
Bio availability study of LZK-10 in comparison with unformulated LuteinA randomized, single-dose, double-blind, 6-way, 6-sequence, crossover, study to assess the bioavailability of Luteinsupplementations (LZK-10, 250 mg, 500 mg and 1000 mg) in comparison with normal unformulated Lutein supplementations in healthy volunteers.CTRI/2021/06/034084
The Effect of 12-Week Dietary Intake of Lutein on Minimal Erythema Dose and Other Skin ParametersThe Effect of 12-Week Dietary Intake of Lutein on Minimal Erythema Dose and Other Skin Parameters: Randomised Double-Blind Placebo Controlled StudyNCT03811977
Role of Xanthophylls in Visual FunctionRole of Xanthophylls in Visual FunctionNCT05794074
Effect of supplement containing N-acetyl glucosamine, proteoglycan and lutein, on knee joint symptoms. - a randomized, double blind, placebo-controlled study -Effect of supplement containing N-acetyl glucosamine, proteoglycan and lutein, on knee joint symptoms. - a randomized, double blind, placebo-controlled study - - Effect of supplement containing N-acetyl glucosamine, proteoglycan and lutein, on knee joint symptoms.JPRN-UMIN000020503
To Compare the bioavailability of Lutein formulations - Product A and Product B (Lutein 10 mg/Zeaxanthin 2 mg per capsule) supplementation in healthy, adult human subjects under fed conditions.A double blind, balanced, randomized, two-treatment, single-period, single-dose, parallel, comparative bioavailability study of Lutein/Zeaxanthin formulations - Product A and Product B (Lutein 10 mg/Zeaxanthin 2 mg per capsule) supplementation in healthy, adult human subjects under fed conditions.CTRI/2019/11/022082
Effects of Lutein Supplementation on Cognition and MPOD in Multiple Sclerosis Patients-Lutein and Multiple Sclerosis Experimental Study (LuMES)NCT04843813
Key gene of retinal cholesterol metabolism network in lutein against age-related macular degenerationA study of the key gene of retinal cholesterol metabolism network in lutein against age-related macular degenerationChiCTR1900028680
The effects of Lutein/Zeaxanthin supplementation on cognitive function in adults with self-reported mild cognitive complaintsThe effects of Lutein/Zeaxanthin supplementation on cognitive function in adults with self-reported mild cognitive complaints: a randomised, double-blind, placebo-controlled studyACTRN12621000038897
Food or Supplemental Lutein AbsorptionLutein Absorption Consumed as Supplement, Blended Food, or Wholefood Over 24-hours.NCT04786392
Clinical trial on eye health in healthy elderly volunteers.A randomized, double blind, placebo-controlled, parallel, three-arm study to evaluate the comparative safety and comparative efficacy of Lutein and Zeaxanthin with or without natural mixed carotenoids to assess positive correlation in MPOD and central foveal thickness levels, in healthy adult subjectsCTRI/2020/06/025599
A comparative post marketing surveillance study to compare the efficacy and safety for the combination of Vitamin C, Vitamin E, Lutein, Zeaxanthin, Zinc and copper with the combination of Astaxanthin, L-Glutathione and Lutein (contains Zeaxanthin) in the patients of Age-related macular degeneration.A prospective, open labelled, parallel, multicentric, comparative post marketing surveillance study to compare the efficacy and safety of AREDS 2 formula, the combination of Vitamin C, Vitamin E, Lutein, Zeaxanthin, Zinc and copper with the combination of Astaxanthin, L-Glutathione and Lutein (contains Zeaxanthin) in the patients of Age-related macular degeneration (AMD).CTRI/2021/08/035406
Enriched Eggs for Retina Health in Type 2 DiabetesEffects of DHA and Lutein Enriched Eggs on Retina Health and Metabolic and Physical Parameters in Type 2 Diabetes: a Strategy for Diabetic RetinopathyNCT04496817
Randomized Controlled Trial of LUtein as a Novel Neuroprotective Adjunctive Therapy to Improve Visual Outcome of Rhegmatogenous Retinal Detachment (LUNAR Study)Randomized Controlled Trial of LUtein as a Novel Neuroprotective Adjunctive Therapy to Improve Visual Outcome of Rhegmatogenous Retinal Detachment (LUNAR Study)NCT03932305
Effect of supplement containing lutein on knee joint symptoms. -a randomized, double blind, placebo-controlled study-Effect of supplement containing lutein on knee joint symptoms. -a randomized, double blind, placebo-controlled study- - Effect of supplement containing lutein on knee joint symptoms.JPRN-UMIN000021101