| To Compare the bioavailability of Lutein formulations - Product A and Product B (Lutein 10 mg/Zeaxanthin 2 mg per capsule) supplementation in healthy, adult human subjects under fed conditions. | A double blind, balanced, randomized, two-treatment, single-period, single-dose, parallel, comparative bioavailability study of Lutein/Zeaxanthin formulations - Product A and Product B (Lutein 10 mg/Zeaxanthin 2 mg per capsule) supplementation in healthy, adult human subjects under fed conditions. | CTRI/2019/11/022082 |
| Clinical Trial for Nutrilite Vision Health Product | The Effect of Botanical Formula Containing Lutein Ester and Zeaxanthin on Adults with Eye Fatigue in a Double-Blinded, Placebo-Controlled Study | ChiCTR1800018987 |
| Lutein/Zeaxanthin and Omega-3 Supplementation in Persons Over Age 60 | Lutein/Zeaxanthin and Omega-3 Supplementation in Persons Over Age 60 | NCT00121589 |
| Effect of Lutein, Zeaxanthin supplements on human. | Effect of Lutein, Zeaxanthin supplements on human. - Lutein Zeaxanthin clinical trial | JPRN-UMIN000025699 |
| Effect of Micronutrient Supplementation on the Intestinal Microbiota in Patients With Age-related Macular Degeneration - The Gut-Retina-axis Study | ": Effect of Supplementation With Lutein, Zeaxanthin and Saffron on the Intestinal Microbiota in Patients Suffering From Age-related Macular Degeneration - The Gut-Retina-axis Study""" | NCT06391411 |
| Early Administration of the Lutein/Zeaxanthin in Premature Newborns | Evaluation of the Antioxidant Activity of Lutein/Zeaxanthin Early Administered to Premature Newborns | NCT03340103 |
| Macular Pigment and Glare Disability | Effects of Lutein and Zeaxanthin Upon MPOD and Its Effects Upon Glare Disability, Photostress Recovery, and Contrast Enhancement in Healthy Subjects: A Randomized, Double-blind Placebo-controlled Study | NCT00909090 |
| Lutein, Zeaxathin, and Fish Oil Supplementation | The Role of Lutein, Zeaxanthin, and Fish Oil on Cognitive Function and Bone Health in Healthy Adults | NCT06489873 |
| Do omega-3 fatty acids affect the absorption of lutein and zeaxanthin in humans? | Effect of omega-3-fatty acid addition to lutein and zeaxanthin supplement and their bioavailability in humans | ACTRN12622000837729 |
| To Evaluate Efficacy of Lutemax 2020 (Lutein 10 mg & Zeaxanthin Isomers 2 mg) on Vision and Cognitive Performance in Healthy Children. | A Prospective, Randomized, Double-Blind, Parallel, Placebo- Controlled Study to Evaluate Efficacy of Lutemax 2020 (Lutein 10 mg & Zeaxanthin Isomers 2 mg) on Vision and Cognitive Performance in Children. | CTRI/2022/05/042364 |
| A comparative post marketing surveillance study to compare the efficacy and safety for the combination of Vitamin C, Vitamin E, Lutein, Zeaxanthin, Zinc and copper with the combination of Astaxanthin, L-Glutathione and Lutein (contains Zeaxanthin) in the patients of Age-related macular degeneration. | A prospective, open labelled, parallel, multicentric, comparative post marketing surveillance study to compare the efficacy and safety of AREDS 2 formula, the combination of Vitamin C, Vitamin E, Lutein, Zeaxanthin, Zinc and copper with the combination of Astaxanthin, L-Glutathione and Lutein (contains Zeaxanthin) in the patients of Age-related macular degeneration (AMD). | CTRI/2021/08/035406 |
| Clinical trial on eye health | A Randomized, double-blind, three arm, placebo-controlled clinical study to evaluate the modulatory effect of Lutein and Zeaxanthin supplementation (Gleamax / Vividawn) on MPOD levels along with Glare disability and Contrast enhancement in healthy subjects. - NIL | CTRI/2023/12/060711 |
| Determine Safety & Recommended Phase 2 Dosing of Zeaxanthin Alone or in Combination w/Pembrolizumab in Patients With Metastatic Cancer | A Phase I Study to Determine the Safety and Recommended Phase 2 Dosing of Zeaxanthin Alone or in Combination With Pembrolizumab in Patients With Metastatic Solid Tumors | NCT05232409 |
| The effects of Lutein/Zeaxanthin supplementation on cognitive function in adults with self-reported mild cognitive complaints | The effects of Lutein/Zeaxanthin supplementation on cognitive function in adults with self-reported mild cognitive complaints: a randomised, double-blind, placebo-controlled study | ACTRN12621000038897 |
| The putative beneficial effects of supplemental Lutein (L) and Zeaxanthin (Z) with co-antioxidants in patients with age-related maculopathy: A pilot short term randomised controlled clinical trial of antioxidant supplementation | | ISRCTN94557601 |
| Clinical Trial on Early-Stage Memory Loss (mild cognitive impairment) in Adults Aged 50-70 Years | A randomized, double-blind, placebo controlled, parallel group clinical study for the comparative evaluation of efficacy and tolerability of lutein and zeaxanthin (XanMax2002) in adult subjects with mild cognitive impairment (MCI) - NIL | CTRI/2024/07/071190 |
| The efficacy of different nutritional formulas of lutein, zeaxanthin, and meso-zeaxanthin and their impact on the human body | The impact of formulation on lutein, zeaxanthin, and meso-zeaxanthin bioavailability: a randomized double-blind placebo-controlled study | ISRCTN18206561 |
| Age-Related Eye Disease Study 2 (AREDS2) | Age-Related Eye Disease Study 2 (AREDS2): A Multi-center, Randomized Trial of Lutein, Zeaxanthin and Omega-3 Long-Chain Polyunsaturated Fatty Acids (Docosahexaenoic Acid [DHA] and Eicosapentaenoic Acid [EPA]) in Age-Related Macular Degeneration | NCT00345176 |
| Lutein and Zeaxanthin Clinical trial on Eye health | A Randomized, double-blind, placebo-controlled clinical study to evaluate the modulatory effect of Lutein and Zeaxanthin supplementation on Macular Pigment Optical Density (MPOD), Glare disability and photo stress in healthy subjects. - NIL | CTRI/2024/09/074298 |
| Clinical trial on eye health in healthy elderly volunteers. | A randomized, double blind, placebo-controlled, parallel, three-arm study to evaluate the comparative safety and comparative efficacy of Lutein and Zeaxanthin with or without natural mixed carotenoids to assess positive correlation in MPOD and central foveal thickness levels, in healthy adult subjects | CTRI/2020/06/025599 |
| Clinical trial on Lutein and Zeaxanthin Supplementation on Eye Health in Elderly Adults | A randomized, double blind, placebo controlled, parallel study to evaluate the comparative efficacy of XanMax(R) 2004 (10mg and 20mg Lutein and Zeaxanthin) oral soft gel capsule with that of a placebo soft gel capsule in improving MPOD levels in elderly volunteers. - NIL | CTRI/2024/12/078490 |
| Clinical trail on Eye health with Keratoconjunctivitis Sicca | A Randomized, Double-Blind, two-arm, placebo-Controlled Study to Evaluate the Efficacy and Safety of Lutein 10mg, Meso zeaxanthin 10mg with Zeaxanthin 2mg in Subjects with Keratoconjunctivitis Sicca. - NIL | CTRI/2025/03/083269 |
| Long Term Effects of Lutein/Zeaxanthin and Omega-3- Supplementation on Optical Density of AMD Patients (LUTEGA) | Long Term Effects of Lutein/Zeaxanthin and Omega-3- Supplementation on Optical Density of AMD Patients (LUTEGA) | NCT00763659 |
| A study to assess the effect of Lutein & Zeaxanthin on Visual improvement among thehealthy subjects | A Double-Blind, Placebo-Controlled Trial on the Effects of Lutein and Zeaxanthinon Macular pigment optical density response, Photo stress Recovery, GlareDisability, and Chromatic Contrast - Nil | CTRI/2023/08/057023 |
| The Effects of a Zeaxanthin Intervention on Visuomotor Function | The Effects of a Zeaxanthin Intervention on Visuomotor Function | NCT02017418 |
| Eye Health Clinical study. | A Double-Blind, Placebo-Controlled Trial on the Effects of Lutein and Zeaxanthin on Macular pigment optical density response, Photo stress Recovery, Glare Disability, and Contrast Sensitivity. - NIL | CTRI/2025/05/086293 |
| A randomized, double-blind, placebo-controlled study to investigate the effects of OmniActive Lutemax 2020® oil suspension on skin health attributes | The effects of oral supplementation of lutein and zeaxanthin isomers (Lutemax2020®) on skin color and skin tone: a double-blind and placebo-controlled clinical trial | ISRCTN15646478 |
| Effects of dietary supplementation containing lutein, zeaxanthin, and omega-3 polyunsaturated fatty on the serum carotenoids and fatty acids concentrations, macular pigment and visual function in people with long-term computer display light exposure | Effects of dietary supplementation containing lutein, zeaxanthin, and omega-3 polyunsaturated fatty on the serum carotenoids and fatty acids concentrations, macular pigment and visual function in people with long-term computer display light exposure | TCTR20220904002 |
| Association of Lutein, Zeaxanthin and Brilliant Blue in Chromovitrectomy | A Descriptive Study to Evaluate the Effectiveness of the Dye Compound of the Combination of Lutein, Zeaxanthin and Brilliant Blue in Chromovitrectomy | NCT01627977 |
| Macular Pigment Density Evolution in Unilateral Wet AMD Versus Non AMD Patients With or Without Lutein and Zeaxanthine Supplementation | Assessment of the Evolution of Macular Pigment Density in Two Distinct Populations, Before and After Supplementation With Nutrof Total Versus Dietary Supplement Without Lutein and Zeaxanthin, Using the Macular Pigment Module of Visucam 200 or Visucam 500 (Zeiss). | NCT01404845 |
| Effects of a combined Vitamin D, Omega 3, Co-enzyme Q10, Zeaxanthin, Lutein and Astaxanthin supplement (Lester’s Oil) on Healthy people | Effects of a combined Vitamin D, Omega 3, Co-enzyme Q10, Zeaxanthin, Lutein and Astaxanthin supplement (Lester’s Oil) on Healthy people | ACTRN12616001316493 |
| Dietary Lutein and the Retinopathy of Prematurity | The Placental and Mammary Transfer of Lutein and Zeaxanthin Into the Fetus and the Breast-fed Infant | NCT00672230 |
| Effects of Lutein and Zeaxanthin Supplementation on Age-related Macular Degeneration | Effects of Lutein and Zeaxanthin Supplementation on Age-related Macular Degeneration | NCT01048476 |
| The Effects of Lutein and Zeaxanthin Supplementation on Vision in Patients With Albinism | A Randomized Placebo-controlled Trial to Investigate the Effect of Lutein and Zeaxanthin Supplementation on Macular Pigment and Visual Function in Albinism - LUtein for VIsion in Albinism (LUVIA) | NCT02200263 |
| Effects of Lutein and Zeaxanthin Supplementation on Early Age-related Macular Degeneration | The Effects of Lutein and Zeaxanthin Supplementations on Early Age-related Macular Degeneration | NCT01528605 |
| Effects of lutein/ zeaxanthin on eye health, eye strain, sleep quality, and attention in high electronic screen users | Effects of lutein/ zeaxanthin on eye health, eye strain, sleep quality, and attention in high electronic screen users: a randomised, double-blind, placebo-controlled study | ACTRN12623000427673 |
| Efficacy of Lutein, Zeaxanthine and Trypan Blue to Stain the Anterior Lens Capsule | A Descriptive Study to Evaluate the Efficacy of the Dye Compound of the Combination of Lutein, Zeaxanthin and Trypan Blue to Stain the Anterior Lens Capsule During Cataract Phacoemulsification. | NCT01621789 |
| Lutein and zeaxanthin supplementation in preterm infants to prevent retinopathy of prematurity | LUtein and zeaxanthin SUpplementation in Preterm infants to prevent RetinOpathy of Prematurity: a multicentre prospective randomised double-blind placebo-controlled study | ISRCTN10624844 |
| Long Term Effects of Lutein/Zeaxanthin and Omega-3- Supplementation for Two More Years (LUTEGA 2) | Long Term Effects of Lutein/Zeaxanthin and Omega-3- Supplementation on Optical Density of AMD Patients for Two More Years (LUTEGA 2) | NCT01648660 |
| The effect of the dietary antioxidant supplements lutein and zeaxanthin on retinal macular pigment optical density | Macular pigment response to supplemental lutein and zeaxanthin: a twin heritability study | ISRCTN55089134 |
| The Zeaxanthin and Visual Function Study | Randomized, Double Blind, Lutein Controlled Study of Zeaxanthin and Visual Function in Atrophic Age Related Macular Degeneration Patients | NCT00564902 |
