IMPPAT Phytochemical information: 
Astaxanthin

Astaxanthin
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
The effect of astaxanthin supplementation on cytokeratin 18 levelsThe effect of astaxanthin supplementation on cytokeratin 18 levels in children and adolescents with non-alcoholic fatty liverIRCT20170628034786N3
Effect of Astaxanthin in treatment of PCOSThe Astaxanthin effect on serum inflammatory markers and expression of genes related to ER stress and apoptosis pathway in peripheral blood mononuclear cell in polycystic ovary syndrome womenIRCT20201029049183N2
Oral Supplementation of Astaxanthin on Skin Photoaging, Hydration and ElasticityDouble Blind Placebo Controlled Oral Supplementation of Astaxanthin on Skin Photoaging, Hydration and ElasticityNCT05882084
A comparative post marketing surveillance study to compare the efficacy and safety for the combination of Vitamin C, Vitamin E, Lutein, Zeaxanthin, Zinc and copper with the combination of Astaxanthin, L-Glutathione and Lutein (contains Zeaxanthin) in the patients of Age-related macular degeneration.A prospective, open labelled, parallel, multicentric, comparative post marketing surveillance study to compare the efficacy and safety of AREDS 2 formula, the combination of Vitamin C, Vitamin E, Lutein, Zeaxanthin, Zinc and copper with the combination of Astaxanthin, L-Glutathione and Lutein (contains Zeaxanthin) in the patients of Age-related macular degeneration (AMD).CTRI/2021/08/035406
Effect of ingestion of supplement containing astaxanthin and trans-resveratrol on the serum triglyceride level -A randomized, double-blind, placebo controlled and parallel group study-Effect of ingestion of supplement containing astaxanthin and trans-resveratrol on the serum triglyceride level -A randomized, double-blind, placebo controlled and parallel group study- - Effect of ingestion of supplement containing astaxanthin and trans-resveratrol on the level of serum triglycerideJPRN-UMIN000018070
Exploration study for effect on urinary 8-OHdG level and vascular endothelial function change by ingestion of supplements containing Astaxanthin for 4 weeksExploration study for effect on urinary 8-OHdG level and vascular endothelial function change by ingestion of supplements containing Astaxanthin for 4 weeks - Study for effect by ingestion of supplements containing AstaxanthinJPRN-UMIN000038330
Astaxanthin Reduces Exercising Heart Rate.Astaxanthin Reduces Exercising Heart Rate by 7% in Overweight Individuals.NCT05282355
Astaxanthin for Management of Inflammation in Knee OsteoarthritisEffect of Astaxanthin for Pain, Function, and Inflammation in Patients With Advanced Osteoarthritis Awaiting Total Knee Replacement SurgeryNCT05138549
Clinical study of astaxanthin on glucose metabolism and vascular functionClinical study of astaxanthin on glucose metabolism and vascular function - Clinical study of astaxanthin on glucose metabolism and vascular functionJPRN-UMIN000045518
Evaluation of Medicinal properties and actions of Astaxanthin in HumanAnalysis of Polycrest Behaviour Of Astaxanthin - NiLCTRI/2023/08/056909
Efeect of Astaxanthin supplementation in women with Polycystic ovary syndrome (PCOs)Effect of Astaxanthin supplementation on the insulin sensivity, lipid profile, and clinical symptoms in women with PCOS: A randomized clinical studyIRCT20231001059573N1
Study of the Efficacy and Safety of Antioxidants Astaxanthin as an Adjuvant Therapy for Community Acquired Pneumonia Patients.Study of the Efficacy and Safety of Astaxanthin as an Adjuvant Therapy for Community Acquired Pneumonia Patients.NCT06334874
Using Astaxanthin in treatment of bone regenerationAdditive effect of astaxanthin in the periodontal regeneration of human intra-bony defects-A randomised clinical trialCTRI/2020/03/024069
Effect of astaxanthin on autophagy in infertile women with polycystic ovary syndromeEffect of Astaxanthin on Ovarian Granulosa Cells Autophagy via the AMPK Signaling Pathway, in Infertile Women with Polycystic Ovarian Syndrome undergoing ART; a Triple Blind Randomized Clinical TrialIRCT20231028059882N1
Impact of astaxanthin on health and performance among firefightersImpact of astaxanthin supplementation on markers of cardiometabolic health and tactical performance among firefightersISRCTN10901752
A randomized, double-blind, placebo-controlled clinical trial for early Astaxanthin intervention in Alzheimer's diseaseA randomized, double-blind, placebo-controlled clinical trial for early Astaxanthin intervention in Alzheimer's diseaseChiCTR2000034755
Astaxanthin in polycystic ovary syndromeThe effect of Astaxanthin on expression of ER stress pathway genes and apoptotic factors in granulosa cells of Polycystic ovary syndrome patient candidate for Assisted reproductive technology: RCT(Triple-blind)IRCT20201029049183N1
The effect of astaxanthin on rheumatoid arthritisThe effect of astaxanthin supplementation on antioxidant status, inflammation status, disease severity and physical performance in patients with rheumatoid arthritisIRCT20200429047235N2
Effect of astaxanthin intake in patients affected by type 2 diabetes mellitusEffect of Astaxanthin intake on expression of miR-146a and miR-126 in plasma, oxidative stress and inflammation markers and glycemic profile, compared with placebo in patients with type 2 diabetes mellitusIRCT2015081623645N1
Astaxanthin in VaricoceleInvestigating the Effectiveness of Astaxanthin on Induced Amount of ROS in Semen and Sperm QualityAmong Patients with Varicocele through Nrf2/Keap1 PathwayIRCT20230924059501N1
Effect of Astaxanthin, Natural plant-based oil, Vitamin E and Vitamin D3 on oxidative stress in overweight and obese womenEffect of Astaxanthin, Natural plant-based oil, Vitamin E and Vitamin D3 on oxidative stress in overweight and obese women: A randomized double blind, placebo-controlled clinical trialTCTR20210220001
Effects of Isoflavone Combined With Astaxanthin on Skin AgingEffects of Isoflavone Combined With Astaxanthin on Skin AgingNCT02373111
Evaluating the effect of astaxanthin supplement on the levels of trace elements in patients with type 2 diabetes treated with metforminEvaluation the effect of astaxanthin supplementation on the plasma and cellular levels of magnesium, zinc, copper and selenium in patients with type 2 diabetes treated by metforminIRCT20190305042939N3
Effect of Astaxanthin on the Patients With Alzheimer DiseaseEffect of Astaxanthin on the Patients With Alzheimer DiseaseNCT05015374
?Astaxanthin in spinal cord injuryInvestigating the effects of Astaxanthin on the recovery of patients with complete spinal cord injury: A clinical trial studyIRCT20231024059828N1
Comparing the Effectiveness of Daily VS Every other day of Oral Astaxanthin on Improvement Skin Elasticity, A Randomized, Double-blind Clinical TrialComparing the Effectiveness of Daily VS Every other day of Oral Astaxanthin on Improvement Skin Elasticity, A Randomized, Double-blind Clinical TrialTCTR20210321001
The Effect of Astaxanthin on Endometriosis PatientsThe Effect of Astaxanthin on the Expression of Genes Involved in Wnt /ß-catenin Pathway in the Eutopic Endometrium and Inflammatory Factors Downstream of the NF-?B Pathway in the Serum of Women with Endometriosis Candidate for Assisted Reproductive TechniquesIRCT20220625055274N1
Efficacy and Safety of Astaxanthin in Volunteer With Refraction ErrorsEfficacy and Safety of Astaxanthin in Volunteer With Refraction ErrorsNCT05009810
effect of supplement containing Astaxanthin and alpha linolenic acid in coronary artery stenosisA clinical trial to compare the effect of supplement containing Astaxanthin and alpha linolenic acid with placebo on serum levels of leptin and adiponectin, hs-CRP, miocardio vascular adhesion factors, nitric oxide and lipid profile in patients with mild to moderate coronary artery stenosisIRCT2016050327727N1
Lipid-lowering Effects of an Astaxanthin Supplement in Volunteers With Mild DyslipidaemiaRandomized, Double-blind, Placebo-controlled, Parallel-group Design, Monocentric Study on Lipid-lowering Effects of an Astaxanthin Supplement in Volunteers With Mild DyslipidemiaNCT02343497
Clinical Trial of Anti-oxidant Astaxanthin in Insulin-resistant SubjectsA Double-blinded, Placebo-controlled, Clinical Trial of Insulin-sensitizing, Anti-inflammatory and Anti-oxidant Activities of Astaxanthin in Insulin-resistant SubjectsNCT03310359
Efficacy study of oral astaxanthin to improve brain function for the middle aged and elderlyEfficacy study of oral astaxanthin to improve brain function for the middle aged and elderly - Efficacy study of oral astaxanthin to improve brain functionJPRN-UMIN000022299
A randomized, double blind, placebo-controlled trial of zinc and astaxanthin among mild glucose intoleranceA randomized, double blind, placebo-controlled trial of zinc and astaxanthin among mild glucose intolerance - A randomized, double blind, placebo-controlled trial of zinc and astaxanthin among mild glucose intoleranceJPRN-UMIN000017118
Effects of antioxidant supplementation with Astaxanthin on blood vessels in renal transplant patientsEffects of supplementation with Astaxanthin on oxidative stress and vascular structure and function in renal transplant patientsACTRN12608000159358
THE ROLE OF ASTAXANTHIN IN SEMEN PARAMETERS AND DNA INTEGRITY IN SUBFERTILE MALETHE ROLE OF ASTAXANTHIN IN SEMEN PARAMETERS AND DNA INTEGRITY IN SUBFERTILE MALE IN SOUTH ASIAN POPULATION - NILCTRI/2025/04/083979
Positive Effects of Haematococcus Astaxanthin on Oxidative Stress and Lipid Profile in Overweight and Obese AdultsNCT01167205
Bioavailability of Astaxanthin FormulationsBioavailability of Astaxanthin FormulationsNCT03443882
Evaluation of Astaxanthin Properties on Anti-fatigueShort-term Astaxanthin Supplementation Enhances Cycling Performance and Attenuates Exhaustive Exercise-induced Muscle Damage and Oxidative Stress in Young Healthy Adults: A Randomized Controlled TrialNCT06593535
Astaxanthin supplementation to augment fat oxidation and improve performance in endurance trained athletesAstaxanthin supplementation to augment fat oxidation and improve performance in endurance trained athletes - Astaxanthin supplementation in cyclistNL-OMON36483
Astaxanthin Supplementation in CyclistsNCT01241877
The effect of Astaxanthin on the expression of genes involved in WNT/ß-catenin pathway in granulosa cells and inflammatory factors in the serum of PCOs patients candidate for ARTThe effect of Astaxanthin on the expression of genes involved in WNT/ß-catenin pathway in granulosa cells and inflammatory factors in the serum of PCOs patients candidate for assisted reproductive technologiesIRCT20221005056092N1
Effect of aerobic exercise and astaxanthin supplementation on humanin protein expressionThe effect of 8 weeks of aerobic exercise and astaxanthin supplementation on humanin protein expression, miR-17, miR-146a and miR-155, and inflammatory conditions, oxidative stress and apoptosis in women with type 2 diabetesIRCT20230225057524N1
Astaxanthin Effects on Osteoarthritis Associated Pain and Inflammatory IndicatorsAstaxanthin Effects on Osteoarthritis Associated Pain and Inflammatory IndicatorsNCT03664466
The Effect of Astaxanthin Administration on poor Ovarian ResponseThe Effect of Astaxanthin Administration on Oxidative Stress Markers and Inflammatory Cytokines in the Follicular Fluid of Patients with Poor Ovarian Response: A Triple-Blind, Randomized control trialIRCT20230223057510N1
The randomized, pracedo-controlled, double brind crinical trial for the choroidal circulation of 12mg astaxanthin ingestion.The randomized, pracedo-controlled, double brind crinical trial for the choroidal circulation of 12mg astaxanthin ingestion. - The crinical trial for the choroidal circulation of 12mg astaxanthin ingestion.JPRN-UMIN000004754
Effects of Astaxanthin SupplementationImpact of Four Weeks of Astaxanthin Supplementation at Varied Doses on Muscle Pain, Muscle Damage Markers, and Total Antioxidant Status in Exercising Males: A Randomized Controlled TrialNCT06511960
A placebo-controlled trial of astaxanthin in subjects with nonalcoholic fatty liver diseaseA placebo-controlled trial of astaxanthin in subjects with nonalcoholic fatty liver disease - AX-NAFLD-1JPRN-UMIN000008524
A study to evaluate the effect of intake of astaxanthin on the status of stress and sleep in adult.A study to evaluate the effect of intake of astaxanthin on the status of stress and sleep in adult. - A study to evaluate the effect of intake of astaxanthin on the status of stress and sleep.JPRN-UMIN000033863
The effect of twelve weeks of high-intensity functional training with Astaxanthin supplementation on some inflammatory markers in men with obesityThe effect of twelve weeks of high-intensity functional training with Astaxanthin supplementation on some inflammatory and antioxidant markers, adipokines, myokines, and hepatokines in men with obesityIRCT20151228025732N76
Prospective, randomized, open-label,clinical trial comparing the effects of astaxanthin and placebo on blood pressure, endothelial function and makers for cardiovascular diseasesProspective, randomized, open-label,clinical trial comparing the effects of astaxanthin and placebo on blood pressure, endothelial function and makers for cardiovascular diseases - Effects of astaxanthin on blood pressure and endothelial functionJPRN-UMIN000020782
Effect of Astaxanthin, Natural plant-based Oil, Vitamin E and VitaminD3 on Inflammatory Biomarkers in Overweight and Obese Women : A Randomized, Double-Blind, Placebo-Controlled Clinical TrialEffect of Astaxanthin, Natural plant-based Oil, Vitamin E and VitaminD3 on Inflammatory Biomarkers in Overweight and Obese Women : A Randomized, Double-Blind, Placebo-Controlled Clinical TrialTCTR20210305003
Clinical Trial of Astaxanthin Formulation With Exercise in Sarcopenia ElderlyProtocol for a Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Impact of a Daily Dose of an Astaxanthin Formulation Alone and With Exercise Training on Skeletal Muscle Function in the ElderlyNCT03368872
Investigating the effect of astaxanthin supplementation on heart failureThe effect of astaxanthin supplementation on inflammatory markers, oxidative stress indices, lipid profile, uric acid level, blood pressure, endothelial function, quality of life and disease symptoms in heart failure subjects.IRCT20200429047235N3
Impact of Astaxanthin on Cognition in Recreationally Active FemalesImpact of Astaxanthin on Cognition in Recreationally Active FemalesNCT06460181
Astaxanthin Formulation BioavailabilityBioavailability Testing of Astaxanthin FormulationsNCT02397811
The Effectiveness of Astaxanthin plus F. on facial skin qualityThe Effectiveness of Astaxanthin plus F. on facial skin quality , A Randomized , double-blind , placebo-controlled trialTCTR20210301005
Evaluating the effect of astaxanthin supplement in patients with type 2 diabetes Treated by metforminEvaluation of the effects of astaxanthin on markers related to autophagy and study of inflammatory activity by expression of microRNAs in type ? diabetic patients are treated with metforminIRCT20190305042939N1
Oral Astaxanthin and Semen Quality, Fertilization and Embryo Development in Assisted Reproduction Techniques ProceduresEffect of Oral Administration of Astaxanthin on Semen Quality, Fertilization and Embryo Development in Assisted Reproduction Techniques ProceduresNCT02310087
Physiological and Molecular Influences of Astaxanthin Supplementation on Heat Strain in HumansPhysiological and Molecular Influences of Astaxanthin Supplementation on Heat Strain in HumansNCT02088242
The effect of astaxanthin treatment on oxidative stress in womenThe effect of astaxanthin treatment on oxidative stress in women - Effect of astaxanthin treatment on oxidative stressJPRN-UMIN000011834
Safety and Pharmacokinetics of Phaffia Rhodozyma AstaxanthinSafety and Pharmacokinetics of Astaxanthin-Rich Carotenoid Extract (AstaFerm™) Administered as a Single Oral Dose to Healthy AdultsNCT03807050
Effect of Astaxanthin Phytochemical, Vitamin D3, Omega-3 and Vitamin E supplement on severity of mild to moderate COVID-19 SymptomsAssessing the effect of Astaxanthin Phytochemical, Vitamin D3, Omega-3 and Vitamin E ?upplement on the severity of COVID-19 Symptoms of Patients with mild to Moderate Severity- a randomized double blind controlled Clinical TrialIRCT20140804018677N9
Astaxanthin and AGE-RAGE-Inflammation AxisEffect of Astaxanthin on Advanced Glycation End Products (AGE)-Receptor for AGE (RAGE)-Inflammation Signaling pathway in Women with Polycystic Ovarian Syndrome-Associated InfertilityIRCT20231028059882N2
The Effect of Astaxanthin on Oxidative Stress Indices in Patients With Polycystic Ovary SyndromeThe Effect of Astaxanthin on Oxidative Stress Indices in Serum, and Induction of Signaling Pathways in Granulosa Cells in Patients With Polycystic Ovary SyndromeNCT03991286
Comparative evaluation of Transcutaneous Electrical Nerve Stimulation (TENS) and astaxanthin in Myofascial Pain Dysfunction Syndrome (MPDS)Comparative evaluation of efficacy of Transcutaneous Electrical Nerve Stimulation (TENS), Transcutaneous Electrical Nerve Stimulation with Muscle relaxant, Transcutaneous Electrical Nerve Stimulation with Astaxanthin and Astaxanthin alone in the management of Myofascial Pain Dysfunction Syndrome (MPDS)CTRI/2023/05/052453
Astaxanthin (2 mg) + Lycopene (1.8 mg) + D-Alpha-Tocopherol (10 IU) For The Treatment Of Skin AgingA Randomized, Double-Blind, Placebo-Controlled Trial Evaluating The Safety And Efficacy Of An Oral Supplement Containing Astaxanthin (2 mg) + Lycopene (1.8 mg) + D-Alpha-Tocopherol (10 IU) For The Treatment Of Skin AgingNCT03460860
Effects of a combined Vitamin D, Omega 3, Co-enzyme Q10, Zeaxanthin, Lutein and Astaxanthin supplement (Lester’s Oil) on Healthy peopleEffects of a combined Vitamin D, Omega 3, Co-enzyme Q10, Zeaxanthin, Lutein and Astaxanthin supplement (Lester’s Oil) on Healthy peopleACTRN12616001316493
Effect of Astaxanthin in Moderate to Severe Knee OsteoarthritisEffect of Astaxanthin in Reducing Disease Activity in Moderate to Severe Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled TrialNCT05437601
Astaxanthin, Exercise Inflammation, Skin HealthInfluence of Astaxanthin Supplementation on Exercise-Induced Inflammation and Skin HealthNCT05409092
A Study to Evaluate the Effect of Astaxanthin in Healthy ParticipantsA Prospective, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effect of Supplemental Astaxanthin in Healthy Female Adult ParticipantsNCT05376501