IMPPAT Phytochemical information: 
Butylphthalide

Butylphthalide
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
Clinical trial on efficacy and safety of add-on treatment of Butylphthalide in patients with Parkinson's disease in early and moderate stageClinical trial on efficacy and safety of add-on treatment of Butylphthalide in patients with Parkinson's disease in early and moderate stageChiCTR-IPR-16009395
DL-3-n-butylphthalide Treatment in Patients With Mild to Moderate Alzheimer's Disease Already Receiving DonepezilDL-3-n-butylphthalide Treatment in Patients With Mild to Moderate Alzheimer's Disease Already Receiving Donepezil : A Multi Center, Prospective Cohort StudNCT02711683
The Effectiveness and Safety of Butylphthalide Soft Capsules in Secondary Prevention of Ischemic Stroke TrialThe Effectiveness and Safety of Butylphthalide Soft Capsules in Secondary Prevention of Ischemic Stroke TrialNCT00724724
Efficacy and Safety of Butylphthalide Combined with Edaravone Dexborneol in Acute Ischemic Stroke Patients Undergoing ThrombectomyEfficacy and Safety of Butylphthalide Combined with Edaravone Dexborneol in Acute Ischemic Stroke Patients Undergoing ThrombectomyChiCTR2500100650
Butylphthalide's Safety and Efficacy for Improving Neurological Function Prognosis in Patients With Cardiac Arrest (BNCA Trial)Butylphthalide's Safety and Efficacy for Improving Neurological Function Prognosis in Patients With Cardiac Arrest (BNCA Trial): A Single-Center, Randomized, Double-Blind, Placebo-Controlled StudyNCT06353334
Clinical efficacy and safety of butylphthalide sequential therapy combined with mechanical thrombectomy in the treatment of acute cerebral infarctionClinical efficacy and safety of butylphthalide sequential therapy combined with mechanical thrombectomy in the treatment of acute cerebral infarctionChiCTR2200064311
Effect of butylphthalide on new cerebral microbleeds in patients with acute ischemic strokeEffect of butylphthalide on new cerebral microbleeds in patients with acute ischemic strokeChiCTR2000033486
Butyl phthalide sodium chloride injection effects on inflammatory factorsButyl phthalide sodium chloride injection effects on inflammatory factorsChiCTR-CPR-15007593
A Randomized Controlled Trial on the Efficacy and Safety of Butylphthalide in Reducing Myocardial Infarction Size and Improving Outcomes in STEMI Patients After Primary PCIA Randomized Controlled Trial on the Efficacy and Safety of Butylphthalide in Reducing Myocardial Infarction Size and Improving Outcomes in STEMI Patients After Primary PCI - A Prospective, Multicenter, Randomized, Placebo, Double-blinded End Trial.NCT06704685
Neuroprotective Effect of Butylphthalide for Cardiac Arrest PatientsNeuroprotective Effect of Butylphthalide Injection on Patients With Return of Spontaneous Circulation After Cardiac Arrest:a Multicenter, Randomized Clinical TrialNCT06572085
Efficacy and Safety Analysis of Butylphthalide Soft Capsules in Secondary Prevention of Stroke: a Real-World StudyEfficacy and Safety Analysis of Butylphthalide Soft Capsules in Secondary Prevention of Stroke: a Real-World StudyChiCTR2000034481
Effects of butylphthalide on reperfusion, collateral circulation and clinical prognosis in patients with acute ischemic strokeEffects of butylphthalide on perfusion, collateral circulation and clinical prognosis in patients with acute ischemic strokeChiCTR2000038241
Clinical study on the difference of short-term and long-term efficacy of butylphthalide in acute ischemic stroke patients with different TOAST typesClinical study on the difference of short-term and long-term efficacy of butylphthalide in acute ischemic stroke patients with different TOAST typesChiCTR2000040839
For Patients With Ischemic Stroke, Clinically Study the Effectiveness and Safety of Butylphthalide.A Real-world Study on the Effectiveness and Safety of Butylphthalide in the Treatment of Ischemic Stroke.NCT05068349
Using Real-world Evidence to Analyze the Clinical Effects and Adverse Events of Butylphthalide in Stroke PatientsA Real-world Retrospective Study on the Effectiveness and Safety of Butylphthalide in the Treatment of Ischemic StrokeNCT05086874
DL-3-n-butylphthalide Therapy for Cerebral Hypoperfusion in Unilateral Internal Carotid System Stenosis (BUTCH): A Clinical Multiple-center StudyDL-3-n-butylphthalide Therapy for Cerebral Hypoperfusion in Unilateral Internal Carotid System Stenosis (BUTCH): A Clinical Multiple-center StudyChiCTR2100053112
The effect of butylphthalide treatment on cerebral perfusion and cognitive function in patients with vascular dementiaThe effect of butylphthalide treatment on cerebral perfusion and cognitive function in patients with vascular dementiaChiCTR2200056012
Effects of DL-3-n-butylphthalide capsule on collateral circulation and cognitive function in patients with chronic cerebral hypoperfusion: a multicenter, randomized, double-blind, controlled clinical trialEffects of DL-3-n-butylphthalide capsule on collateral circulation and cognitive function in patients with chronic cerebral hypoperfusion: a multicenter, randomized, double-blind, controlled clinical trialChiCTR2200059143
The therapeutic efficacy of donepezil combined with dL-3-n-butylphthalide in patients with post-stroke cognitive impairment: A prospective clinical studyThe therapeutic efficacy of donepezil with or without dL-3-n-butylphthalide in patients with post-stroke cognitive impairment: A prospective clinical studyChiCTR2200062940
A Multi-center, Randomized, Double Blinding, Placebo-Controlled Clinical Trial of Dl-3-Butylphthalide in the Treatment of Amyotrophic Lateral SclerosisA Multi-center, Randomized, Double Blinding, Placebo-Controlled Clinical Trial of Dl-3-Butylphthalide in the Treatment of Amyotrophic Lateral SclerosisChiCTR-IPR-15007365
Real world study of butyl phthalide sodium chloride injection in the treatment of acute ischemic strokeReal world study of butyl phthalide sodium chloride injection in the treatment of acute ischemic strokeChiCTR2100046094
Efficacy of Butylphthalide on Symptomatic Atherosclerotic Stenosis in Middle Cerebral ArteryEfficacy of Butylphthalide on Symptomatic Atherosclerotic Stenosis in Middle Cerebral Artery (SICAS): a Prospective, Randomized, Double-blinded, Placebo-controlled, Multiple-center Trial.NCT06331494
A clinical study of dl-3-n-butylphthalide in improving the prognosis of patients with acute ischemic strokeA clinical study of dl-3-n-butylphthalide in improving the prognosis of patients with acute ischemic strokeChiCTR-IPR-16010051
Study on the efficacy of butylphthalide in the treatment of cognitive impairment after delayed stroke: a randomized controlled trial.A 24-week multicenter, randomized controlled study to evaluate the efficacy of NBP on Delayed-onset Post Stroke Cognitive ImpairmentChiCTR2000032555
Efficacy of aspirin and clopidogrel combined with DL-3 n-butylphthalide on psychiatric, neurological and behavioural functions in acute ischemic stroke of middle-aged and elderly peopleEfficacy of aspirin and clopidogrel combined with DL-3 n-butylphthalide on psychiatric, neurological and behavioural functions in acute ischemic stroke of middle-aged and elderly peopleChiCTR2000030824
Efficacy of aspirin and clopidogrel combined with Butylphthalide on frequent transient ischemic attack of atherosclerotic origin with ABCD2Efficacy of aspirin and clopidogrel combined with Butylphthalide on frequent transient ischemic attack of atherosclerotic origin with ABCD2ChiCTR2000030423
Dl-3-n-butylphthalide and Cerebrolysin Treatment in Acute Ischemic StrokeA Comparison of Safety and Efficacy of Dl-3-n-butylphthalide and Cerebrolysin on Neurological and Behavioral Outcomes in Acute Ischemic Stroke: a Randomized, Double-blind Study.NCT02149875
Efficacy of aspirin and clopidogrel combined with Butylphthalide on atherosclerotic transient ischemic attack with ABCD2Efficacy of aspirin and clopidogrel combined with Butylphthalide on atherosclerotic transient ischemic attack with ABCD2ChiCTR2000030272
NBP in Patients With Moyamoya Disease of High Risk for Ischemic Cerebrovascular EventsA Multi-center, Randomized, Single-blind, Placebo-controlled Study of Dl-3-n-butylphthalide in Patients With Moyamoya Disease of High Risk for Ischemic Cerebrovascular Events After Extracranial-to-intracranial Revascularization SurgeryNCT04205578
The effect of DL-3-n-butylphthalide on improving collateral circulation in patients with cerebral artery stenosisThe effect of DL-3-n-butylphthalide on improving collateral circulation in patients with cerebral artery stenosisChiCTR1900028005
A Multi-center, Randomized, Double Blinding, Controlled Phase III Clinical Trial of Dl-3-Butylphthalide Injection in the Treatment of Acute Cerebral InfarctA Multi-center, Randomized, Double Blinding, Controlled Phase III Clinical Trial of Dl-3-Butylphthalide Injection in the Treatment of Acute Cerebral InfarctChiCTR-TRC-09000483
Efficacy and safety of butylphthalide in the treatment of delayed encephalopathy caused by acute carbon monoxide poisoning/carbon monoxide poisoning: a multicenter, randomized, controlled clinical studyEfficacy and safety of butylphthalide in the treatment of delayed encephalopathy caused by acute carbon monoxide poisoning/carbon monoxide poisoning: a multicenter, randomized, controlled clinical studyChiCTR1900027779
Butylphthalide for Preventing Restenosis After Intracranial and Extracranial Artery StentingButylphthalide for Preventing Restenosis After Intracranial and Extracranial Artery StentingNCT01405248
Effect of DL-3-n-butylphthalide on preventing ischemic cerebral vascular diseases in the patients with intracranial atherosclerotic stenosis, BUPICASEffect of DL-3-n-butylphthalide on preventing ischemic cerebral vascular diseases in the patients with intracranial atherosclerotic stenosis, BUPICASChiCTR2500104739
Intervention and Protection of dl-3-n-Butylphthalide in Acute Cerebral HemorrhageIntervention and Protection of dl-3-n-Butylphthalide in Acute Cerebral HemorrhageChiCTR1900026222
Study for the Role of Butylphthalide in Delaying the progression of Parkinson's disease (PD), Vascular Parkinson's disease (VP) and Parkinsonism-plus syndrome (PPS)Study for the Role of Butylphthalide in Delaying the progression of Parkinson's disease (PD), Vascular Parkinson's disease (VP) and Parkinsonism-plus syndrome (PPS)ChiCTR1900023725
A Clinical Study on the Treatment of Cerebral Small Vascular DiseaseA Multi-center, Randomized, Double-Blind, Placebo-Controlled Study of Dl-3-Butylphthalide on the Treatment of Small Cerebral Vessel DiseaseNCT04078204
Efficacy and Safety of Butylphthalide Soft Capsule for the Treatment of Vascular DementiaA Multi-center, Random, Double Blind and Placebo Control Phase III Clinical Study on the Efficacy and Safety of Butylphthalide Soft Capsule for the Treatment of Vascular DementiaNCT03804229
Investigation of new approaches and technologies in the management of Parkinson's diseaseThe efficacy of Butylphthalide on cognitive impairment of patients with idiopathic PD and DBS patients: A Randomized, double-blind, placebo-controlled, multicenter trialChiCTR1800017084
Observation on the protective effect of butylphthalide on the blood - brain barrier after stroke in patients with thrombolysisObservation on the protective effect of butylphthalide on the blood - brain barrier after stroke in patients with thrombolysisChiCTR1800015325
Treatment of SCA3/MJD patients with oral DL-3-n-butylphthalide: A randomized, double blind, placebo controlled trialTreatment of SCA3/MJD patients with oral DL-3-n-butylphthalide: A randomized, double blind, placebo controlled trialChiCTR-IIR-17012717
Effect of Butylphthalide on HGF Expression in Ischemic Stroke PatientsEffect of Butylphthalide on HGF Expression in Ischemic Stroke PatientsChiCTR-OPN-17011341
The Efficacy of Butylphthalide Soft Capsules in Patents With VCINDThe Efficacy of Butylphthalide Soft Capsules in Patents With VCIND:A Randomized, Double-blind,and Neuroimaging StudyNCT02993367
Efficacy and Safety of DL-3-n-butylphthalide in Adult Patients with Moyamoya Disease after Indirect Revascularization: A Prospective, Multicenter, Randomized Controlled Clinical TrialEfficacy and Safety of DL-3-n-butylphthalide in Adult Patients with Moyamoya Disease after Indirect Revascularization: A Prospective, Multicenter, Randomized Controlled Clinical TrialChiCTR2500104834
Efficacy and Safety of Early Initiation of Butylphthalide Treatment in Patients With Acute Ischemic Stroke.Effect of Early Initiation of Butylphthalide on Neural Function in Patients With Acute Ischemic Stroke -A Prospective, Multicenter, Randomized, Open-label, Blinded End TrialNCT06472921
Research for the correlation between the polymorphism of CYP3A4, CYP3A5 and CYP2E1 gene and the serum concentration and efficacy of butylphthalide in patients with acute ischemic strokeResearch for the correlation between the polymorphism of CYP3A4, CYP3A5 and CYP2E1 gene and the serum concentration and efficacy of butylphthalide in patients with acute ischemic strokeChiCTR1900024664
Effects of DL-3-n-butylphthalide on Chemotherapy-Induced Cognitive ImpairmentEffects of DL-3-n-butylphthalide on Chemotherapy-Induced Cognitive Impairment (NBP CICI):a Prospective, Randomized, Double Blinded, Multicenter, Placebo Controlled StudyNCT06508671