| Adjunctive Pregnenolone in Post-Traumatic Stress Disorder (PTSD) and Depression in Operations Enduring Freedom and Iraqi Freedom (OEF/OIF) Veterans | Adjunctive Pregnenolone in PTSD and Depression in OEF/OIF Veterans | NCT00993629 |
| A Study of Pregnenolone in the Treatment of Individuals With Autism | An Open-Label Pilot Study of Pregnenolone in the Treatment of Individuals With Autism | NCT01881737 |
| Pregnenolone and L-theanine Augmentation in the Treatment for Schizophrenia and Schizoaffective Disorders | Addition of Both Pregnenolone and L-theanine to Ongoing Antipsychotic Treatment for Schizophrenia and Schizoaffective Disorders: an 8-week, Randomized, Double-blind, Placebo-controlled Multicenter Study | NCT01831986 |
| The Effects of One-Time Pregnenolone, Dehydroepiandrosterone (DHEA), or Placebo Administration On Withdrawal Symptoms, Mood, Craving And Cigarette Evaluation Ratings In Male Smokers | The Effects of One-Time Pregnenolone, DHEA, Or Placebo Administration On Withdrawal Symptoms, Mood, Craving And Cigarette Evaluation Ratings In Male Smokers | NCT00900900 |
| Detection of Dehydroepiandrosterone (DHEA) Augmentation Doping: Pilot Study | Open, non-randomized interventional study in healthy adult volunteers to obtain blood and urine samples for steroid analysis: To identify the serum and urine changes in the androgen profile in (a) men administered DHEA with and without pregnenolone and (b) women administered DHEA with and without anti-estrogens. | ACTRN12611000042943 |
| Study Using Pregnenolone to Treat Bipolar Depression | A Randomized, Double Blind, Placebo-controlled Trial of Pregnenolone for Bipolar Depression | NCT01409096 |
| Testing the Interactive Effects of Delta-9-Tetrahydrocannabinol and Pregnenolone: Sub-Study I | Testing the Interactive Effects of Delta-9-Tetrahydrocannabinol and Pregnenolone: Sub-Study I | NCT02811939 |
| Pregnenolone in the treatment of women with chronic schizophrenia | Pregnenolone in the treatment of women with chronic schizophrenia: a double blind randomized trial | IRCT201504211556N76 |
| Pregnenolone and Marijuana Dependence | Effect of Pregnenolone on Cue-reactivity in Marijuana-dependent Individuals | NCT02439814 |
| Pregnenolone for the Treatment of Alcohol Use Disorder | Pregnenolone for the Treatment of Alcohol Use Disorder | NCT05781009 |
| Feasibility Trial of Pregnenolone for Posttraumatic Stress Disorder and Alcohol Use Disorder | Feasibility Trial of Pregnenolone for Posttraumatic Stress Disorder and Alcohol Use Disorder | NCT04464148 |
| Pilot Trial of Pregnenolone in Autism | Randomized Controlled Pilot Trial of Pregnenolone in Autism | NCT02627508 |
| Pregnenolone in the Management of Schizophrenia Patients | Efficacy and Safety of Pregnenolone Augmentation in the Management of Schizophrenia Patients: a Randomised Double-Blind Placebo-Controlled Trial | NCT00174889 |
| Effects of Pregnenolone on Perceived Social Isolation | Effects of Pregnenolone on Perceived Social Isolation: A Double-blind Randomized Electrical Neuroimaging Study | NCT02826577 |
| Testing the Interactive Effects of Delta-9-Tetrahydrocannabinol and Pregnenolone | Testing the Interactive Effects of Delta-9-Tetrahydrocannabinol and Pregnenolone | NCT02576912 |
| Pregnenolone Trial for Depression in Bipolar Disorders or Recurrent Major Depressive Disorder With Substance Abuse | A Double-blind Placebo Controlled Trial of Pregnenolone for Depression in Patients With Bipolar Disorders or Recurrent Major Depressive Disorder and a History of Substance Abuse | NCT00223197 |
| Development of Pregnenolone as a Treatment for Depression | NCCIH Development of Pregnenolone as a Treatment for Depression R61 Phase | NCT03645096 |
| Pregnenolone Augmentation in the Treatment of Patients With Recent-Onset Schizophrenia | Pregnenolone Augmentation in the Treatment of Patients With Recent-Onset Schizophrenia: an 8-week, Randomized, Double-blind, Placebo-controlled Trial | NCT00847600 |
| Pilot Study of Pregnenolone Augmentation Targeting Cognitive Symptoms in Persistently Symptomatic Patients With Schizophrenia | Pilot Study of Pregnenolone Augmentation Targeting Cognitive Symptoms in Persistently Symptomatic Patients With Schizophrenia | NCT00560937 |
| Pregnenolone for Cognitive and Negative Symptoms in Schizophrenia | Pregnenolone for Cognitive and Negative Symptoms in Schizophrenia | NCT00728728 |
| Targeting Cognition in PTSD: Pregnenolone Augmentation of SSRIs | Targeting Cognition in PTSD: Pregnenolone Augmentation of SSRIs | NCT00560781 |
| Adjunctive Pregnenolone in Veterans With Mild TBI | Adjunctive Pregnenolone in Veterans With Mild TBI | NCT00623506 |
| Study of a Neurocognition Enhancing Agent in Patients With Schizophrenia | A 10-week, Randomized, Double-Blind, Placebo-Controlled Trial of a Neurocognition Enhancing Agent(Pregnenolone) in Patients With Schizophrenia. | NCT00894842 |
| Efficacy of Pregnenolone in Patients With Schizophrenia | Efficacy of Pregnenolone in Patients With Schizophrenia | NCT00615511 |
