| Analgesic Efficacy of Intravenous Hyoscine-N-Butylbromide (HNB) in Abdominal Colic Associated With Acute Gastroenteritis | Assessment of Analgesic Efficacy and Safety of Intravenous Hyoscine-N-Butylbromide in Patients With Abdominal Colic Associated With Acute Gastroenteritis; a Randomized, Double-blind, Placebo Controlled Study | NCT02508142 |
| The Safety and Efficacy of Naltrexone and Scopolamine Utilized in the Treatment of Major Depression | The Safety and Efficacy of Naltrexone and Scopolamine Utilized in Combination in the Treatment of Major Depression: A Double Blinded, Randomized, Controlled Pilot Study | NCT03386448 |
| A dose-response study of scopolamine in major depressive disorder | A randomised, double-blind, active placebo-controlled, parallel groups dose-response study of intravenous scopolamine in major depressive disorder | ACTRN12619000569101 |
| Buscopan Versus Acetaminophen for Acute Abdominal Pain in Children | Hyoscine Hydrobromide (Buscopan) Versus Acetaminophen for Acute Abdominal Pain in Children: A Randomized Controlled Trial | NCT02582307 |
| The effect of premedication Hyoscine-N-butylbromide before Hysterosalpingography for diagnosis of proximal tubal obstruction in Infertile Women : A Randomized Double-Blind Controlled Trial | The effect of premedication Hyoscine-N-butylbromide before Hysterosalpingography for diagnosis of proximal tubal obstruction in Infertile Women : A Randomized Double-Blind Controlled Trial | TCTR20151121001 |
| Evaluation of the Efficacy of the Injection of Botulinum Toxin A vs Scopolamine Patches in the Treatment of Drooling in Children With Cerebral Palsy | Evaluation of the Long-term Efficacy of the Injection of Botulinum Toxin A Into the Salivary Glands Versus Scopolamine Patches in the Treatment of Drooling in Children Over 4 Years Old With Cerebral Palsy. | NCT03616067 |
| Effect of Hyoscine on Reducing Catheter Related Discomfort | Effect of Intravenous Hyoscine on Catheter Induced Bladder Discomfort after Transurethral Resection of Prostate | IRCT2013071013934N1 |
| Effect of Intravenous Hyoscine Butylbromide Injection on Labour in High Risk Women | Study the Effect of Intravenous Hyoscine Butylbromide Injection on the Duration and Progress of First Stage Labour in High Risk Women | NCT03055390 |
| Clozapine-induced Hypersalivation - Feasibility Trial | A Feasibility Study of Glycopyrrolate in Comparison to Hyoscine Hydrobromide and Placebo in the Treatment of Hypersalivation Induced by Clozapine | NCT02613494 |
| Scopolamine in Healthy Volunteers | Open-label, Dose-escalating, Non-randomized, Single-Center Study to Determine the Safety and Pharmacokinetic Profiles of Scopolamine in Healthy Volunteers | NCT03874130 |
| : Effect of warm shower and intravenous injection of hyoscine on the pain severity and duration of the active phase of labor in primiparous women | : Effect of warm shower and intravenous injection of hyoscine on the pain severity and duration of the active phase of labor in primiparous women | IRCT2015012610324N22 |
| Effectiveness Study of Scopolamine Combined With Escitalopram in Patients With MDD | A Double-blind, Controlled, Randomized Study Comparing Escitalopram Combined With Scopolamine or Escitalopram in Patients With Major Depressive Disorder | NCT03131050 |
| Hyoscine ButylBromide for Intrapartum Analgesia | Efficacy of Intravenous Hyoscine ButylBromide as an Analgesic During the First Stage of Labor: A Randomized Controlled Trial | NCT02557087 |
| Study to Evaluate the Effects of BPN14770 on Scopolamine-induced Cognitive Impairment in Healthy Volunteers | A Randomized, Double-blind, Placebo-controlled, Single-dose, 6-Period Crossover Study to Evaluate the Effects of BPN14770 on Scopolamine-induced Cognitive Impairment in Healthy Volunteers | NCT03030105 |
| Determine the Bioequivalence of Two Formulations of Hyoscine Butylbromide. | A Single Center, Single-dose, Double-blind, Randomized, Two Period Crossover, Two Stage Design to Determine Bioequivalence of Two Formulations Containing Hyoscine Butylbromide 10mg Sugar Coated Tablets, Under Fasting Conditions | NCT02516098 |
| Ketamine and Hyoscine for postoperative catheter related bladder discomfort | Comparison Between Ketamine And Hyoscine For Management Of Postoperative Catheter Related Bladder Discomfort. A Randomized Controlled Double Blind Study. An Experience From Cairo University Hospital in EGYPT. | PACTR201510001279149 |
| The Effects of Preoperative Scopolamine Patch Application on the Postoperative Nausea and Vomiting in MVD Surgery | The Effects of Preoperative Scopolamine Patch Application on the Postoperative Nausea and Vomiting in Microvascular Decompression Surgery | NCT02968082 |
| Assessment of the efficacy and the influence on swallowing function of transdermal scopolamine for ALS patinets' drooling | Assessment of the efficacy and the influence on swallowing function of transdermal scopolamine for ALS patinets' drooling - SCOPOLA-D | JPRN-UMIN000011494 |
| Does scopolamine improve attention more than placebo in healthy volunteers and what does this tell us about mechanisms of attention? | Does scopolamine improve selective attention and cognition more than placebo in healthy male volunteers? | ACTRN12611000603910 |
| TAK-071 Scopolamine-Induced Cognitive Impairment Study | A Randomized, Double-Blind, Sponsor Unblinded, Placebo-Controlled, 5-Period Crossover, Phase 1b Study To Evaluate The Effects Of Single Oral Administration of TAK-071 On Scopolamine-Induced Cognitive Impairment In Healthy Subjects | NCT02918266 |
| A Comparative Bioavailability and Adhesion Performance Study, Comparing a New Scopolamine Transdermal Delivery System Formulation to the Currently Established Reference Transdermal Delivery System in Healthy Adult Participants. | A Randomized, Single-center, Crossover, Comparative Bioavailability and Adhesion Performance Study, Comparing Single Administrations of a New Scopolamine Transdermal Delivery System Formulation to the Currently Established Reference Transdermal Delivery System in Healthy Adult Participants. | NCT02839135 |
| The effect of intravenous Hyoscine-N-butylbromide on active phase labor pain in primigravid women | The effect of intravenous Hyoscine-N-butylbromide on active phase labor pain in primigravid women | IRCT2015080423444N1 |
| The Application of Spasmolytic in PCLE Examination of Superior Gastrointestinal Endoscope | A Clinical Analysis of Scopolamine Hydrobromide in Probe-based Confocal Laser Endomicroscopy for Gastroendoscopy Examination | NCT02811341 |
| The Use of EEG in Alzheimer's Disease, With and Without Scopolamine - A Pilot Study | Development of a Diagnostic Tool for Alzheimer's Disease | NCT02273895 |
| Roflumilast and Donepezil to Reverse Scopolamine Induced Cognitive Deficits in Healthy Adults | A Randomized, Double-Blind, Placebo Controlled, 4-Period, Cross-Over Study to Evaluate the Effects of Single Oral Administrations of Roflumilast in Combination With Donepezil on Reversing Scopolamine (Hyoscine) Induced Deficits in Psychomotor and Cognitive Function in Healthy Adults | NCT02051335 |
| Pharmacokinetic and Efficacy Profile Intranasal Scopolamine Spray | Pharmacokinetic and Efficacy Profile of Low-Dose Intranasal Scopolamine Spray for Motion Sickness | NCT02155309 |
| Scopolamine Patch Pharmacokinetics in Healthy Adults | Absolute Bioavailability/Pharmacokinetic and Residual Drug Analysis of the Transderm Scop System in Healthy Adults | NCT03029650 |
| Scopolamine Patch and Acupressure Point P6 Stimulation for Reduction of Nausea and Vomiting During Cesarean Section | Is the Application of Scopolamine Patch With or Without Intra-operative Acupressure Point P6 Stimulation More Effective Than Intra-operative Acupressure Point P6 Stimulation Alone? | NCT02960113 |
| A study of the blood levels of physostigmine and hyoscine and associated symptoms following intravenous administration in healthy male and female participants. | A randomised, double-blind, placebo-controlled, crossover, dose escalation study to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of physostigmine salicylate and hyoscine hydrobromide by continuous, intravenous infusion to healthy Caucasian male and female volunteers, given separately and in combination. | ISRCTN78730348 |
| Hyoscine and Hyoscine-Promethazine effects on the delivery | The effect of intramascular Hyoscine and Hyoscine-Promethazine on the duration of labour and deliveryoutcomes to nuliparous pregnant women(triple-blind randomize control trial) | IRCT201512163027N29 |
| The effect of hyoscine and EMLA cream on Catheter related bladder discomfort (CRBD) | Comparison of the effect of hyoscine and EMLA cream on Catheter related bladder discomfort (CRBD) in patients undergoing non-urologic surgery | IRCT20210228050530N1 |
| Hyoscine Butyl-bromide Versus Ondansetron for Nausea and Vomiting During Cesarean Section Under Spinal Anesthesia | Hyoscine Butyl-bromide Versus Ondansetron for Nausea and Vomiting During Cesarean Section Under Spinal Anesthesia: A Randomized Clinical Trial | NCT04785118 |
| Effect of Hyoscine N Butyl Bromide (HNBB)on duration and pain relief in labour | To evaluate the effect of Hyoscine N Butyl Bromide ( HNBB) on the progress of labour in term pregnancies in a tertiary care institute | CTRI/2020/12/030069 |
| Management of Abdominal Pain in Acute Gastroenteritis Patients With Hyoscine Butylbromide | Management of Abdominal Pain in Acute Gastroenteritis Patients With Hyoscine Butylbromide: Randomized Double Blind Placebo Controlled Trial | NCT04682860 |
| A randomized control trial of Hyoscine N-Butylbromide versus Lidocaine pretreatment for alleviating pain on propofol injection | A randomized control trial of Hyoscine N-Butylbromide versus Lidocaine pretreatment for alleviating pain on propofol injection | TCTR20201207002 |
| Antispastic efficasy of l-menthol spray on the duodenal mucosa compared with intravenous administration of scopolamine butylbromide for endoscopic retrograde cholangiopancreatography (ERCP) | Antispastic efficasy of l-menthol spray on the duodenal mucosa compared with intravenous administration of scopolamine butylbromide for endoscopic retrograde cholangiopancreatography (ERCP) - Antispastic efficasy of l-menthol compared with scopolamine butylbromide for ERCP | JPRN-UMIN000008101 |
| Hyoscine butylbromide co-administered with ibuprofen in dysmenorrhea | A phase IV randomized, double-blind, 3-treatment, 3-period, 6-sequence crossoverclinical trial to assess the efficacy and safety of hyoscine butylbromide co-administeredwith ibuprofen compared to placebos in participants suffering from primary dysmenorrhea | EUCTR2019-004138-41-DE |
| The Effect of Hyoscine-N-butylbromide (HBB, Buscopan) in Augmented Labour Among Primigravidae | A Randomised Control Study: The Effect of Hyoscine-N-butylbromide (HBB, Buscopan) in Augmented Labour Among Primigravidae | NCT04349722 |
| Rectal versus Intramuscular Hyoscine: its Effects on Shortening the First Stage of Labor in Term Primigravid Women | Rectal versus Intramuscular Hyoscine: its Effects on Shortening the First Stage of Labor in Term Primigravid Women | TCTR20200410005 |
| A Clinical Trial of Scopolamine Versus Placebo for Individuals with Bipolar Disorder who are Experiencing a Depressive Episode (SCOPE-BD) | A Randomised Double-Blinded Placebo-Controlled Trial to Assess the Efficacy and Safety of Scopolamine Compared to Placebo in Individuals with Bipolar Disorder who are Experiencing a Depressive Episode (SCOPE-BD) - SCOPE-BD | EUCTR2017-003112-39-IE |
| Hyoscine Butylbromide for Prevention of Bradycardia During Cesarean Section | Prophylactic Use of Iv Hyoscine Butylbromide for Prevention of Bradycardia During Cesarean Section Under Spinal Anaesthesia. a Randomized Controlled Trial | NCT04069078 |
| Comparison of the effect of Hyoscine N-Butylbromide on the propofol injection pain | Comparison of the effect of Hyoscine N-Butylbromide and Lidocaine 2% on the propofol injection pain | IRCT20190109042309N2 |
| Evaluation of the effect of oral hyoscine on the rate of cervical opening in term pregnancy | Evaluation of the effect of oral hyoscine on cervix status (Bishop score) in term pregnancy | IRCT20180819040830N1 |
| Evaluation of Hyoscine butylbromide effects on pain severity of first stage of labor and fetal heart rate in multiparous women | Evaluation of Hyoscine butylbromide effects on pain severity of first stage of labor and fetal heart rate in multiparous women | IRCT20180424039407N1 |
| A comparative study of vaginal hyoscine butyl bromide and misoprostol on cervical ripening for gynecological intrauterine procedures | A comparative study of vaginal hyoscine butyl bromide and misoprostol on cervical ripening for gynecological intrauterine procedures | IRCT20151228025732N68 |
| Effect of Hyoscine on Peristaltism and Cardiovascular Outcomes | Efficacy of Low Dose Hyoscine N-butyl Bromide Versus Usual Dose on Anti Motility Response and Cardiovascular Outcomes During Endoscopic Retrograde Cholangiopancreatography in patients with billiary tract disorder | IRCT20180421039368N1 |
| Ef?cacy of Hyoscine-n-butylbromide in Catheter-related Bladder Discomfort After Elective Cesarean Section. | Ef?cacy and Safety of Hyoscine-n-butylbromide for the Alleviation of Early Catheter-related Bladder Discomfort After Elective Cesarean Delivery: a Randomized Controlled Trial | NCT03513250 |
| Celecoxib Versus Hyoscine Butyl-bromide in Reducing Pain Associated With IUD. | Celecoxib Versus Hyoscine Butyl-bromide in Reducing Pain Perception During Copper T380A Intrauterine Device Insertion: a Randomized Double-blind Controlled Trial | NCT03499743 |
| A randomised double blind placebo controlled study on the effect of intramuscular hyoscine butylbromide and drotaverine in the first stage of active p | A randomised double blind placebo controlled study on the effect of intramuscular hyoscine butylbromide and drotaverine in the first stage of active phase of labour on labour and delivery outcome | PACTR201803003208333 |
| Hyoscine Butylbromide Effect on Duration of Labor | Hyoscine Butylbromide Effect on Duration of Labor in Nulliparous Women: A Randomized, Double Blind, Controlled Trial | NCT03441217 |
| The Effect of Hyoscine Butylbromide on Shortening of First and Second Stages of Labor | | NCT02839213 |
| Effect Of Intravenous Hyoscine -N-Butyl Bromide In Management Of Prolonged Labor In Nulliparous | Effect Of Intravenous Hyoscine -N-Butyl Bromide In Management Of Prolonged Labor In Nulliparous | NCT03430362 |
| COMPARISON OF 60MG AND 40MG DOSES OF HYOSCINE BUTYLBROMIDE ON LABOR OUTCOMES AT MOI TEACHING AND REFERRAL HOSPITAL, ELDORET, KENYA. | COMPARISON OF 60MG AND 40MG DOSES OF HYOSCINE BUTYLBROMIDE ON LABOR OUTCOMES AT MOI TEACHING AND REFERRAL HOSPITAL, ELDORET, KENYA | TCTR20180123004 |
| Ketamine and Scopolamine Infusions for Treatment-resistant Major Depressive Disorder | Combination of Anticholinergic and Glutamatergic Effects in Treatment-resistant Major Depressive Disorder. A Pilot Study | NCT01613820 |
| Comparison of the effects of Hyoscine and Acupressure on Hugo point on length of delivery | Comparison of the effects of Hyoscine and Acupressure on Hugo point (LI 4) on Length of delivery stages in nuliparous women: A randomized controlled clinical trial. | IRCT201709293027N39 |
| A programme to develop a skin patch containing two medicines (physostigmine and hyoscine) - study 2: Assessment of blood levels of the two medicines and any associated symptoms in healthy male participants wearing four prototype skin patches | A Dose-escalation Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Four Transdermal Patch Formulations (F4-F7) of Hyoscine and Physostigmine in Healthy Male Subjects | ISRCTN29062676 |
| A Trial for Peroperative Procedure and Postoperative Pain After Rectal Misoprostol or Rectal Hyoscine Administration | A Randomised Trial for Postoperative Pain After Rectal Misoprostol or Rectal Hyoscine Administration | NCT03359655 |
| ?Effect of hyoscine on pain and spasm during uterine graphy | The effect of hyoscine on pain and fallopian tubes spasm during and after hysterosalpingography in infertile women | IRCT2017021132455N2 |
| Comparing the effect of hyoscine and diazepam in management of true peripheral vertigo | Comparing the effect of hyoscine and diazepam in management of true peripheral vertigo | IRCT2016100815640N5 |
| delivery | Comparison of effects of transcutaneous electrical nerve stimulation and of pharmaceutical hyoscine– promethazine compound on duration of the second phase of labor | IRCT201604144317N10 |
| Effect of Intravenous Hyoscine Butylbromide Injection on the Course and Duration of First Stage of Labour in Primigavidae | Effect of Intravenous Hyoscine Butylbromide Injection on the Course and Duration of First Stage of Labour in Primigavidae | NCT02824679 |
| Comparison of Pheniramine and Hyoscine for management of post operative catheter related bladder discomfort after general anaesthesia. | Comparative evaluation of Pheniramine versus Hyoscine for management of post operative catheter related bladder discomfort after general anaesthesia. | CTRI/2021/08/035651 |
| The effect of cervical Hyoscine on the length of the first and second stages of labor | The effect of cervical Hyoscine on the length of the first and second stages of labor of nulliparous women referred to Niknafs maternity hospital in Rafsanjan: A clinical trial | IRCT20181219042051N3 |
| A randomized control trial of Hyoscine N-Butylbromide versus Lidocaine pretreatment for alleviating pain on propofol injection | A randomized control trial of Hyoscine N-Butylbromide versus Lidocaine pretreatment for alleviating pain on propofol injection | TCTR20211028005 |
| A Novel Usage of Transdermal Scopolamine in Reducing Narcotic Usage in Outpatient Hand Surgery | A Novel Usage of Transdermal Scopolamine in Reducing Narcotic Usage in Outpatient Hand Surgery | NCT04008264 |
| The effect of intramuscular administration of dexamethasone alone or in combination of hyoscine butylbromide in shortening the duration of induced labour in Primigravida | The effect of intramuscular administration of dexamethasone alone or in combination of hyoscine butylbromide in shortening the duration of induced labour in Primigravida | ACTRN12616000208404 |
| Hyoscine butyl bromide versus misoprostol for cervical priming before diagnostic hysteroscopy in premenopausal infertile women in Enugu southeastern Nigeria: A double-blinded randomised controlled trial | Hyoscine bromide versus misoprostol for cervical priming before diagnostic hysteroscopy in premenopausal infertile women in Enugu southeastern Nigeria: A double-blinded randomised controlled trial | PACTR202506541899773 |
| A study of a skin patch containing two medicines (physostigmine and hyoscine) in healthy male participants to assess the blood levels of the two medicines and any associated symptoms. | An open, replicate, two-period, single and multiple-dose, pharmacokinetic and tolerability study of the PHP (150 g/m2) transdermal patch containing physostigmine and hyoscine in healthy, adult Caucasian males. | ISRCTN10362655 |
| The Effect of Hyoscine-n-butylbromide on Nausea and Pain in Laparoscopic Cholecystectomy | The Effect of Hyoscine-N-Butylbromide on Nausea and Pain in Laparoscopic Cholecystectomy: A Prospective Randomized Study | NCT06927817 |
| Effect of hyoscine -n-butylbromide on the duration of active phase of labour in term pregnancies: a randomized-controlled clinical trial. | Effect of hyoscine -n-butylbromide on the duration of active phase of labour in term pregnancies: a randomized-controlled clinical trial. | PACTR202502489216837 |
| A programme to develop a skin patch containing two medicines (physostigmine and hyoscine), Study 1: Assessment of blood levels of the two medicines and any associated symptoms in healthy male participants wearing prototype skin patches | A randomised, double-blind, three-way crossover study to investigate the pharmacokinetics, pharmacodynamics, safety and tolerability after single applications of three transdermal patch formulations of physostigmine and hyoscine in healthy males | ISRCTN21827000 |
| Oral Hyoscine Butyl Bromide With Cervical Lidocaine Cream in Reducing Pain During Hysterosalpingography | Randomized Clinical Trial of Oral Hyoscine Butyl Bromide With Cervical Lidocaine Cream in Reducing Pain During Hysterosalpingography | NCT02710305 |
| COMPARING 2%LIGNOCAINE AND 2%LIGNOCAINE WITH HYOSCINE BUTYLBROMIDE IN PAIN REDUCTION DURING MANUAL VACUUM ASPIRATION FOR INCOMPLETE ABORTION IN JUTH | Comparing 2%Lignocaine and 2%Lignocaine with Hyoscine Butylbromide in Pain Reduction During Manual Vacuum Aspiration For Incomplete Abortion in Juth | PACTR202409853980242 |
| use of hyoscine bromide in labor | Randomised, masked, placebo-controlled study to evaluate the effects of a single intravenous dose of hyoscine bromide on the duration and pain in the latent and active labor | EUCTR2013-001921-19-ES |
| Hyoscine Trial | Hyoscine Butyl-Bromide versus Placebo in Nulliparous Women in Labour: A Randomized Controlled Study | PACTR202409867055348 |
| Effect of Hyoscine-N-Butyl Bromide on Hysterosalpingography-Associated Pain and Tubal Spasm. A Double-Blind Randomized Placebo-Controlled Study | Effect of Hyoscine-N-Butyl Bromide on Hysterosalpingography-Associated Pain and Tubal Spasm. A Double-Blind Randomized Placebo-Controlled Study | PACTR202407618349397 |
| study on the effect of hyoscine on progress of labour and pregnancy outcome | Effect of hyoscine N-Butyl bromide on progress of labour and pregnancy outcome; A randomized control trial | PACTR202407805328722 |
| Cervical ripening /Labour induction in postdate nulliparas; Comparative study of vaginal misoprostol versus vaginal misoprostol with rectal hyoscine-butylbromide | Cervical ripening /Labour induction in postdate nulliparas; Comparative study of vaginal misoprostol versus vaginal misoprostol with rectal hyoscine-butylbromide | PACTR202407560838827 |
| A Study to Investigate the Analgesic Efficacy of Ibuprofen Alone and Ibuprofen Plus Hyoscine-n- Butyl Bromide in Reducing Pain of Outpatient Hysteroscopy | Comparison of the Analgesic Efficacy of Ibuprofen Alone and Ibuprofen Plus Hyoscine-n- Butyl Bromide in Reducing Pain of Outpatient Hysteroscopy: a Randomized, Phase iv, Double-blind Trial | NCT06398054 |
| hyoscine and dexamethasone on cervical preparation | Investigating the effect of injectable hyoscine and dexamethasone on cervical preparation in primiparous women with term pregnancy | IRCT20240222061084N1 |
| Hyoscine Butyl Bromide in Reducing Pain During HSG | Randomized Clinical Trial of Oral Hyoscine Butyl Bromide in Reducing Pain During HSG | NCT02709603 |
| AGADAGA Trial | A COMPARISON OF THE DURATION OF CERVICAL RIPENING WITH USE OF VAGINAL MISOPROSTOL PLUS HYOSCINE-N-BUTYLBROMIDE (HBB) TO VAGINAL MISOPROSTOL ALONE: A DOUBLE-BLIND RANDOMISED CONTROLLED TRIAL | PACTR202112821475292 |
| Frequency of Oculocardiac Reflex in scleral buckling | Comparison of the Effect of Intravenous Atropine and Hyoscine on the Frequency of Oculocardiac Reflex in Scleral Buckling Surgery: A double-blinded Randomized Controlled Clinical Trial | IRCT20120307009229N6 |
| DROTAVERINE HYDROCHLORIDE VERSUS HYOSCINE BUTYLBROMIDE IN REDUCING FIRST STAGE OF LABOUR AMONG NULLIPARAE : A RANDOMIZED CONTROLLED TRIAL | DROTAVERINE HYDROCHLORIDE VERSUS HYOSCINE BUTYLBROMIDE IN REDUCING FIRST STAGE OF LABOUR AMONG NULLIPARAE : A RANDOMIZED CONTROLLED TRIAL | PACTR202206902932545 |
| A double-blind, randomized, cross-over, multi-center efficacy and safety study of ibuprofen plus hyoscine butylbromide for pain management due to primary dysmenorrhea | A double-blind, randomized, cross-over, multi-center efficacy and safety study of ibuprofen plus hyoscine butylbromide for pain management due to primary dysmenorrhea - Study of ibuprofen plus hyoscine butylbromide in patients with primary dysmenorrhoea | EUCTR2022-000843-57-BG |
| Hyoscine before hysteroscopy | Comparing injectable Hyoscine and vaginal misoprostol in cervical ripening before hysteroscopy | IRCT20140224016705N13 |
| efficacy of hyoscine on dilation of the cervix | Evaluation the efficacy of hyoscine on dilation of the cervix before hysteroscopy: an open-labeled randomized control trial | IRCT20220822055772N1 |
| Hyoscine N-butylbromide for preventing propofol injection pain | Hyoscine N-butylbromide for preventing propofol injection pain: A randomized, placebo-controlled, double-blind study in patients undergoing routine outpatient surgery under general anesthesia | ACTRN12616000142437 |
| The effect of hyoscine butylbromide for shortening active phase of the first stage of labor : Double blind placebo-controlled trial | The effect of hyoscine butylbromide for shortening active phase of the first stage of labor : Double blind placebo-controlled trial | TCTR20230411002 |
| How to Reduce Pain in Patients Undergoing Office Hysteroscopy. | A Randomized Double Blinded Placebo-controlled Trial to Compare the Effect of Hyoscine-N-butyl Bromide (HBB) or Celecoxib Administered Alone Versus in Combination to Reduce Pain in Patients Undergoing Office Hysteroscopy. | NCT05911126 |
| Effect of Hyoscine- Bromide on Duration of the First Stage of Labor | Effect of Hyoscine- Bromide on Duration of the First Stage of Labor | NCT06056869 |
| A clinical trial to study the effects of two drugs, ondansetron versus hyoscine in patients undergoing cesarean section under spinal anaesthesia. | """A COMPARATIVE STUDY ON THE HEMODYNAMIC EFFECTS OF HYOSCINE VERSUS ONDANSETRON IN PATIENTS UNDERGOING CESAREAN SECTION UNDER SPINAL ANAESTHESIA"" - NIL" | CTRI/2023/09/057985 |
| Oral Diclofenac Sodium Versus Oral Hyoscine Butyl Bromide During Intrauterine Device Insertion | A Randomized Controlled Trial of 2 Different Methods for Pain Relief During Intrauterine Device Insertion | NCT02714231 |
| Trial of Glycopyrronium versus Hyoscine to treat drooling in children - DRI Trial (Drooling Reduction Intervention) | A single blind study comparing the efficacy of Glycopyrronium and Hyoscine on drooling in children with neurodisability - DRI Trial (Drooling Reduction Intervention) | ISRCTN75287237 |
| The effect of Hyoscine butyl bromide on the duration of the first stage of labour in nulliparous women: A randomised controlled trial in Wuse District Hospital, Abuja. | The effect of Hyoscine butyl bromide on the duration of the first stage of labour in nulliparous women: A randomised controlled trial in Wuse District Hospital, Abuja. | PACTR202402717378543 |
| Oral Hyoscine Butyl Bromide Versus Diclofenac Potassium Before Office Hysteroscopy | Randomized Clinical Trial of Oral Hyoscine Butyl Bromide Versus Diclofenac Potassium in Reducing Pain During Office Hysteroscopy | NCT02714699 |
| effect of morphine + hyoscine and ketorolac + hyoscine on reducing renal colic pain | A comparative of the effectiveness of morphine and hyoscine with ketorolac and hyoscine on pain control in patients with renal colic | IRCT20241022063469N1 |
| Effect of hyoscine on severity of pain, tenderness and rebound tenderness in patients candidate for appendectomy | Effect of hyoscine on severity of pain, tenderness and rebound tenderness in patients candidate for appendectomy | IRCT2015111825123N1 |
| Safety Study of Hyoscine N Butyl Bromide in Active Management of Labor | Efficacy and Safety of Hyoscine N Butyl Bromide on the Augmentation of Labor: a Double-Blind, Placebo - Controlled Trial | NCT02098889 |
| Effect of Hyoscine and Atropine on blood pressure ,heart rate in patient who treated by ECT | Comparisson of the effect of pretreatment with Hyoscine,Atropine and placebo on hemodynamic stability,recovery time,and ECT side effect | IRCT2014100719431N1 |
| Reducing Excess Salivation in clozapine Treatment: hyoscine for the treatment of clozapine induced nocturnal sialorrhoea | Pilot double blind randomised placebo controlled crossover trial of hyoscine hydrobromide for the treatment of clozapine-induced nocturnal sialorrhoea | ISRCTN47146067 |
| The effect of Hyoscine -suppository on labor | The effect of Hyoscine - N - Butyl Bromide suppository on labor pain and process in nuliparous women | IRCT138804282204N1 |
| Efficacy of Mefenamic Acid and Hyoscine for Pain Relief During Saline Infusion Sonohysterography in Infertile Women | Efficacy of Mefenamic Acid and Hyoscine for Pain Relief During Saline Infusion Sonohysterography in Infertile Women. A Double Blind Randomized Controlled Trial | NCT01060696 |
| A programme to develop a skin patch containing two medicines (physostigmine and hyoscine), Study 6: Assessment of blood levels of the two medicines and any associated symptoms in healthy female participants. | A study to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of a single application (one or two dose levels) and multiple applications (one dose level) of the transdermal patch formulations of physostigmine and hyoscine in healthy female subjects | ISRCTN15358284 |
| A programme to develop a skin patch containing two medicines (physostigmine and hyoscine), Study 7: Assessment of effects of an armband covering the skin patch on the blood levels of the two medicines and any associated symptoms in healthy male participants | An investigation of the effects of an armband applied over the F11/21 physostigmine and hyoscine transdermal patch on pharmacokinetic, pharmacodynamic and safety profiles in healthy male subjects | ISRCTN13607674 |
| Comparison of pain relief between aminophylline and hyoscine with morphine in renal colic. | Comparison of pain relief between aminophylline and hyoscine with morphine in patients with renal colic. | IRCT20180805040712N1 |
| Study to Evaluate the Efficacy and Safety of Hyoscine Butylbromide Tablets for the Treatment of Occasional or Recurrent Episodes of Gastric or Intestinal Spasm-like Pain or Discomfort | A Randomized, Double-blind, Double-dummy, Active-controlled, Parallel-group, Multi-center Trial, in Contrast With Hyoscine Butylbromide Capsule 10mg, to Evaluate the Efficacy and Safety of Hyoscine Butylbromide Tablets 10 mg (20mg, 3 Times Daily, Orally) Over a Period of 3 Days for the Treatment of Occasional or Recurrent Episodes of Self-reported Gastric or Intestinal Spasm-like Pain | NCT02242305 |
| Pilot double blind randomised placebo controlled crossover trial of Hyoscine for the treatment of Clozapine induced nocturnal sialorrhoea. - Reducing Excess Salivation Trial (REST) | Pilot double blind randomised placebo controlled crossover trial of Hyoscine for the treatment of Clozapine induced nocturnal sialorrhoea. - Reducing Excess Salivation Trial (REST) | EUCTR2009-016300-23-GB |
| Scopolamine Challenge Study | A Randomized, Double-Blind, Sponsor Unblinded, Placebo Controlled, 5-Way, Crossover Study To Evaluate The Effects Of Single Oral Administrations of PF-05212377 (SAM-760), A 5-HT6 Antagonist, On Scopolamine Induced Deficits In Psychomotor And Cognitive Function In Healthy Young Adults | NCT01213355 |
| PET and MRI Imaging With Scopolamine at the Muscarinic M1 Receptor | A Trial to Evaluate Target Occupancy of Scopolamine at the Muscarinic M1 Receptor | NCT06014385 |
| The effect of simultanous intramuscular injection of Atropin and Hyoscine on labor progress in primigravid pregnant women | The effect of simultanous intramuscular injection of Atropin and Hyoscine on labor progress in primigravid pregnant women | IRCT201304284686N6 |
| A randomized, double-blind, placebo-controlled cross-over study of scopolamine intravenous injection on refractory depression | A randomized, double-blind, placebo-controlled cross-over study of scopolamine intravenous injection on refractory depression | ChiCTR2200063641 |
| A randomised controlled blinded trial to investigate the effect of hyoscine butylbromide during colonoscopy on rates of polyp detection. | In patients undergoing standard fibreoptic colonoscopy at a single centre, randomly allocated to receive hyoscine butylbromide or saline; a comparison of polyp detection rates between the two groups is to be undertaken to improve detection of colonic polyps. | ACTRN12608000600347 |
| The Antidepressant Efficacy of the Anticholinergic Scopolamine | The Antidepressant Efficacy of the Anticholinergic Scopolamine | NCT00369915 |
| Drotaverine Hydrochloride Versus Hyoscine-N-butylbromide for Duodenal Antimotility During Endoscopic Retrograde Cholangiopancreatography (ERCP) | Drotaverine Hydrochloride Versus Hyoscine-N-butylbromide for Duodenal Antimotility During ERCP: a Prospective, Multicenter Randomized Controlled Trial | NCT00731198 |
| The effect of injectable scopolamine in patients with major depressive disorders | The augmentation effect of injectable scopolamine in the improvement of clinical symptoms of patients with major depressive disorder | IRCT20231017059749N1 |
| The Effect of Hyoscine Butyl Bromide on the First Stage of Labor in Term Pregnancies | The Effect of Hyoscine Butyl Bromide on the First Stage of Labor in Term Pregnancies | NCT00409890 |
| A clinical trial to study effectiveness and safety of Fixed dose combination tablets of Hyoscine butylbromide & Mefenamic acid in patients suffering from paroxysmal spastic abdominal pain | A randomized, open label, comparative, multicentric, phase 3 clinical study to assess the efficacy and safety of Fixed dose combination tablets of Hyoscine butylbromide & Mefenamic acid in comparison with Hyoscine butylbromide tablets in patients suffering from paroxysmal spastic abdominal pain - None | CTRI/2011/091/000141 |
| Effect of Hyoscine and Promethazine on Labor Pain | Principal Investigator | NCT01644838 |
| A Double-blind Comparison of Scopolamine With Cinnarizin for Prevention of Simulator Sickness | A Double-blind Randomized Placebo Controlled Comparison of Scopolamine With Cinnarizin for Prevention of Simulator Sickness | NCT01198106 |
| Placebo-Controlled Crossover Study to Evaluate Donepezil and MK-3134 for Reversal of Cognitive Impairment Associated With Scopolamine Administration (3134-005)(COMPLETED) | A Five-Period, Placebo-Controlled, Crossover Study to Evaluate the Effect of Donepezil and MK-3134 on Reversal of Cognitive Impairment Associated With a Single-Dose of Scopolamine. | NCT01181310 |
| A Study of the Use of IV Scopolamine to Augment the Efficacy of Electroconvulsive Therapy (ECT) | A Pilot Study of the Use of IV Scopolamine to Augment the Efficacy of Electroconvulsive Therapy (ECT) | NCT01312844 |
| Clinical re-assessment of combination scopolamine and chlorpromazine on heroin relapse | Clinical re-assessment of combination scopolamine and chlorpromazine on heroin relapse | ChiCTR-TRC-09000490 |
| Comparison of Aprepitant Versus Aprepitant and Transdermal Scopolamine for Preventing Postoperative Nausea and Vomiting | A Randomized, Double-blind Comparison of Oral Aprepitant Alone vs Oral Aprepitant and Transdermal Scopolamine for Preventing Postoperative Nausea and Vomiting | NCT00717054 |
| A programme to develop a skin patch containing two medicines (physostigmine and hyoscine), Study 3: Assessment of blood levels of the two medicines and any associated symptoms in healthy male participants wearing four prototype skin patches. | A Two-part Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Applications of Four Transdermal Patch Formulations of Hyoscine and Physostigmine in Healthy Male Participants | ISRCTN16859029 |
| A trial of medications in comparison to dummy tablets for the treatment of drooling caused by clozapine. | A 3-arm multi-centre randomised placebo-controlled trial of glycopyrrolate or hyoscine hydrobromide for the treatment of clozapine-induced hypersalivation | ISRCTN36536677 |
| Does the Hyoscine N-Butylbromide Administered During Colonoscopy Increase the Adenoma Detection Rate? | Does Hyoscine N-butylbromide Administered During Colonoscopy Increase the Polyp Detection Rate? a Randomized, Single Center, Double Blind, Placebo-controlled Study | NCT01609855 |
| USE OF BUSCOPAN AS AN EASIER OF FIRST STAGE OF LABOUR IF CERVIX RIGIDITY IS PREVIOUSLY DETERMINED BY VAGINAL EXPLORATION | EFFICACY OF ADMINISTRATION OF HYOSCINE BUTILBROMIDE (BUSCOPAN®) ON PREGNANT WOMEN IN FIRST STAGE OF LABOUR IN CASE OF CERVIX RIGIDITY. (BBH V.04-2013 EUDRACT: 2012-005198-30) - BUSCOPAN USE IN CERVIX RIGIDITY IN LABOUR | EUCTR2012-005198-30-ES |
| A programme to develop a skin patch containing two medicines (physostigmine and hyoscine), study 4: Assessment of blood levels of the two medicines and any associated symptoms in healthy male participants with Fitzpatrick Grade 5 skin pigmentation. | A Randomised, Double-Blind, Placebo-Controlled, Crossover Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of a Single Application of a Transdermal Patch Formulation of Hyoscine and Physostigmine in Healthy Male Subjects with Pigmented Skin of Grade 5 on the Fitzpatrick Skin Scale | ISRCTN73285902 |
| A programme to develop a skin patch containing two medicines (physostigmine and hyoscine), study 5: Assessment of blood levels of the two medicines and any associated symptoms in healthy male participants | A two-part study to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of single and multiple applications of the F11/25 transdermal patch formulation of hyoscine and physostigmine in healthy male participants | ISRCTN79173829 |
| Relative Bioavailability Study to Investigate and to Compare Two Different Formulations of Hyoscine Butylbromide in Healthy Male and Female Volunteers | Relative Bioavailability Study to Investigate and to Compare Two Different Formulations of Hyoscine Butylbromide, Following Oral Administration in Healthy Male and Female Volunteers (an Open-label, Randomised, Single Dose, Two-way Crossover, Phase I Study) | NCT01734902 |
| The effect of adding hyoscine to vaginal misoprostol on shotening the induction time of abortion | The effect of adding hyoscine to vaginal misoprostol on shotening the induction time of abortion | IRCT201207259491N3 |
| Comparison of Oral Aprepitant and Transdermal Scopolamine for Preventing Postoperative Nausea and Vomiting | A Randomized, Double-blind Comparison of Oral Aprepitant Alone Versus Oral Aprepitant and Transdermal Scopolamine for Preventing Postoperative Nausea and Vomiting | NCT00659737 |
| Assessment of Indomethacin , Hyoscine and Piroxycam administration effect before embryo transfer versus routine method on ART outcome. | Effect of administration of Indomethacin , Hyoscine suppository , piroxycam capsule versus routine method before Embryo Transfer on pregnancy rates in ICSI cycles in Vali-e-Asr hospital | IRCT138807252565N3 |
| Study to Evaluate Efficacy and Safety of Oral Doses of Hyoscine Butylbromide for the Treatment of Occasional Abdominal Pain, Cramping, and Discomfort | A Double-blind, Placebo-controlled, Randomized, Parallel Group Study of the Efficacy and Safety of Oral Doses of 20 mg Hyoscine Butylbromide When Used On-demand up to 7 Episodes Over a Period of 6 Weeks for the Treatment of Occasional Episodes of Self-reported Abdominal Pain, Cramping, and Discomfort Associated With Cramping in an OTC-like Study Population | NCT02242292 |
| The preventive effect of hyoscine butylbromide on catheter-related bladder discomfort in the post-anesthesia care unit | The preventive effect of hyoscine butylbromide on catheter-related bladder discomfort in the post-anesthesia care unit | KCT0000662 |
| Assessment of the value of hyoscine butylbromide (Buscopan®) in optimising image quality for patients undergoing pelvic magnetic resonance imaging | | ISRCTN56242729 |
| Assessment Of The Effects Of Single Doses Of An Investigational Drug, Given Alone Or With Donepezil, On Scopolamine-Induced Changes In Memory And Learning In Healthy Adults | A Randomized, Double-Blind, Sponsor Unblinded, Placebo- And Positive- Controlled Study To Evaluate The Effects Of Single Oral Administrations Of PF-04995274, Alone Or In Combination With Donepezil, On Scopolamine-Induced Deficits In Psychomotor And Cognitive Function In Healthy Adults | NCT01345864 |
| Effects of Transdermal Scopolamine on Occupational Performance | Effects of Transdermal Scopolamine on Occupational Performance | NCT00374478 |
| Hyoscine Butyl Bromide for Management of Prolonged Labor | Use of Hyoscine Butyl Bromide for Management of Prolonged Labor in Nulliparous Women, A Randomized Controlled Trial | NCT01854073 |
| Effect of Hyoscine butylbromide on the rate of cervical dilatation in labour. | Effect of hyoscine butylbromide on the rate of cervical dilatation in active phase of labour: a randomized control trial | PACTR201403000779211 |
| Effect of scopolamine with propofol on nausea and vomiting | Comparison of scopolamine with propofol on nausea and vomiting in cesarean section under spinal anesthesia | IRCT20201207049639N6 |
| A randomized, double-blind, double-dummy, single dose, 4-way cross-over study to develop an anti-cholinergic pharmacological challenge with mecamylamine in comparison to scopolamine | A randomized, double-blind, double-dummy, single dose, 4-way cross-over study to develop an anti-cholinergic pharmacological challenge with mecamylamine in comparison to scopolamine - Mecamylamine challenge in healthy volunteers | NL-OMON37435 |
| Basic and clinical study of scopolamine extracted from Flos Lonicerae in the treatment of perioperative pain syndrome | Basic and clinical study of scopolamine extracted from Flos Lonicerae in the treatment of perioperative pain syndrome | ChiCTR2200056236 |
| To compare Scopolamine versus Ketamine in Treatment Resistant Depression | To Compare the therapeutic efficacy of Scopolamine versus Ketamine in Treatment Resistant Depression | CTRI/2021/09/036952 |
| Heart rate changes in strabismus surgery | Comparison of intravenous lidocaine and hyoscine buthylbromide with placebo for oculocardiac reflex frequency in strabismus surgery | IRCT201311069229N4 |
| Nebulizer Delivery of Intranasal Scopolamine | Nebulizer Delivery of Intranasal Scopolamine | NCT04999449 |
| Muscarinic modulation of human electroencephalography (EEG) activity using scopolamine | Measuring the effects of intravenous scopolamine on the human EEG in healthy volunteers | ACTRN12622000228785 |
| Clinical Efficacy of Spasmofen Suppository in the Emergency Treatment of Renal ColicA randomized, double blind, double dummy comparative trial | Spasmofen suppository (Ketoprofen combined with Hyoscine-butylbromide) versus Ketorolac intravenous injection in emergency treatment of renal colic | ACTRN12614000246684 |
| A programme to develop a skin patch containing two medicines (physostigmine and hyoscine), Study 8: Assessment of effects of consecutive 24-hour applications of patches for 21 days on the blood levels of the two medicines and any associated symptoms in healthy male and female participants | A double-blind investigation of the effects of daily applications of the physostigmine and hyoscine transdermal patch (NAPS2 F11/21) with an armband on the pharmacokinetic (PK), pharmacodynamic (PD) and safety profiles over a 21-day period in healthy male and female Caucasian subjects | ISRCTN62968791 |
| A Study to Evaluate the Intramuscular Administration of Scopolamine | A Double-Blind, Randomized, Placebo-Controlled, Dose-Escalation Study To Evaluated The Safety, Tolerability, and Pharmacokinetics Of Intramuscular Administration Of Scopolamine Hydrobromide Trihydrate, Injection | NCT04314713 |
