IMPPAT Phytochemical information: 
Methyl butyrate

Methyl butyrate
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
Effect of Yogurt Fortified with beta-Hydroxy beta-Methyl Butyrate (HMB) in Sarcopenic ElderlyEvaluating the Effect of Yogurt Fortified with beta-Hydroxy beta-Methyl Butyrate (HMB), Vitamin D, and Vitamin C on Fat-Free Mass, Muscle Strength, and Physical Functionality in Sarcopenic ElderlyIRCT20171223038017N1
Investigating the effect of beta-hydroxy beta-methylbutyrate in bariatric surgeryEvaluation the effect of beta-hydroxy beta-methylbutyrate supplementation on the prevention of postoperative sarcopenia in patients undergoing bariatric surgery: a double-blind clinical trial studyIRCT20200301046655N4
Effect of beta-hydroxy-beta-methylbutyrate (HMB) enriched oral nutrition supplement on surgical outcomes and physical performance in colorectal cancer patients: a randomized Controlled TrialEffect of beta-hydroxy-beta-methylbutyrate (HMB) enriched oral nutrition supplement on surgical outcomes and physical performance in colorectal cancer patients: a randomized Controlled TrialTCTR20220606005
Effect of beta-hydroxy beta-methylbutyrate, arginine and glutamine on complication after cardiac surgeryEffect of Beta-hydroxy beta-methylbutyrate, Arginine and Glutamine supplementation in patients undergoing cardiac surgery on postoperative outcomesIRCT20120913010826N31
Effects of beta-hydroxy-beta-methylbutyrate supplementation in decompensated cirrhosis patients with sarcopenia: Randomize controlled trial, Preliminary StudyThe Effects of beta-hydroxy-beta-methylbutyrate supplementation in decompensated cirrhosis patients with sarcopenia: Randomize controlled trial, Preliminary StudyTCTR20240422012
Investigating the Effects of Beta-Hydroxy-Beta-Methylbutyrate on Glucose Handling in Older and Younger Men.Investigating the Effects of Beta-Hydroxy-Beta-Methylbutyrate on Glucose Handling in Older and Younger Men.NCT03018496
Beta-Hydroxy-Beta-Methylbutyrate Supplementation and Physical Activity in Liver Cirrhosis: a Controlled TrialBeta-Hydroxy-Beta-Methylbutyrate Supplementation and Physical Activity in Liver Cirrhosis: a Controlled TrialNCT03892070
A study to assess the effect of supplemenatation of beta-hydroxy-beta-methyl butyrate (HMB) in patients undergoing heart surgery with cardiopulmonary bypass (CPB)A study to assess the outcome of preoperaive supplemenatation of beta-hydroxy-beta-methyl butyrate (HMB) in cardiac surgery using cardiopulmonary bypass (CPB)CTRI/2023/04/051341
Evaluation of the efficacy of high protein high calorie diet include L-Arginine, L-Glutamine and ß-Hydroxy ß-Methylbutyrate on pressure ulcers and anthropometric indices in 20-50 years adults in Kermanshah.Evaluation of the efficacy of high protein high calorie diet include L-Arginine, L-Glutamine and ß-Hydroxy ß-Methylbutyrate on pressure ulcers and anthropometric indices in 20-50 years adultsIRCT20181111041611N4
A Study to Investigate the Effect of ß-Hydroxy-ß-Methylbutyrate (HMB) on Skeletal Muscle Wasting in Early Critical Illness.A Study to Investigate the Effect of ß-Hydroxy-ß-Methylbutyrate (HMB) on Skeletal Muscle Wasting in Early Critical Illness. - HMB-ICUEUCTR2016-003557-15-GB
Beta-Hydroxy-Beta-Methylbutyrate (HMB) Supplementation After Liver TransplantationEffects of Beta-hydroxy-beta-methylbutyrate (HMB) Supplementation After Liver Transplantation: Randomized and Controlled Pilot StudyNCT03234920
Nutritional Intervention for Age-related Muscular Function and Strength Losses-Study 2Year-long Double Blind Study on the Efficacy of a Combination of Beta-hydroxy-beta-methylbutyrate and Vitamin D With and Without Exercise on Muscular Strength and Functionality in Older Adults.NCT02043171
Effects of beta-hydroxy-beta-methylbutyrate on kidney after resistance trainingEffects of beta-hydroxy-beta-methylbutyrate on kidney parameters and body composition inuntrained males after 8 weeks combination resistance trainingIRCT201201158736N1
Nutritional Intervention for Age-related Muscular Function and Strength LossesA Double Blind Study on the Efficacy of a Combination of Beta-hydroxy-beta-methylbutyrate and Vitamin D on Muscular Strength and Functionality in Older Adults.NCT00874575
The effect of Beta-Hydroxy beta-Methyl Butyrate calcium combined with exercise therapy in patients with heart disiase(The effect of HMB-Ca combined with exercise therapy in patients with heart disiase)The effect of Beta-Hydroxy beta-Methyl Butyrate calcium combined with exercise therapy in patients with heart disiase (The effect of HMB-Ca combined with exercise therapy in patients with heart disiase)JPRN-jRCTs031220139
The Effect of ß-hydroxy-ß-methylbutyrate Supplementation on Physical Capacity and Body Composition in Trained AthletesThe Effect of ß-hydroxy-ß-methylbutyrate (HMB) Supplementation on Physical Capacity and Body Composition in Trained AthletesNCT03028649
Comparison of Pre-exercise Beta-hydroxy-beta-methylbutyrate Free Acid (HMB-FA) and Cold Water Therapy for the Attenuation of Muscle Damage and SorenessComparison of Pre-exercise Beta-hydroxy-beta-methylbutyrate Free Acid (HMB-FA) and Cold Water Therapy for the Attenuation of Muscle Damage and Soreness in Experienced Resistance Trained Individuals.NCT01793779
The effects of whey protein and HMB (beta-hydroxy-beta-methylbutyrate) supplementation on muscle strength and muscle mass during resistance exercise training in healthy young malesEffects of whey protein and HMB (beta-hydroxy-beta-methylbutyrate) supplementation on muscle strength and muscle mass during resistance exercise training in healthy young males a: randomized, controlled, double-blind studyACTRN12616000197437
Effects of exercise and/or ß-hydroxy-ß-methylbutyrate supplementation on muscle mass, physical performance and insulin resistance in older diabetes with low muscle mass: a randomized, double-blind, placebo-controlled trialEffects of exercise and/or ß-hydroxy-ß-methylbutyrate supplementation on muscle mass, physical performance and insulin resistance in older diabetes with low muscle mass: a randomized, double-blind, placebo-controlled trialChiCTR2500103322
HMB Cerebral Palsy Pilot Studyß-hydroxy-ß-methylbutyrate (HMB) Pilot Feasibility and Efficacy Study in Cerebral Palsy (CP)NCT05384951
Effect of Exercise With and Without HMB on Body Composition and Muscle Strength in Sickle Cell AnaemiaEffects of ß-hydroxy-ß-methyl Butyrate Supplementation and Resistance Exercise on Body Composition, Muscle Strength and Protein Oxidation in Sickle Cell Anaemia.NCT04001907
Can Beta-Hydroxy-beta-Methylbutyrate Supplementation Counteract Muscle Catabolism in Critically Ill Patients?Can Beta-Hydroxy-beta-Methylbutyrate (HMB) Supplementation Counteract Muscle Catabolism in Critically Ill Patients? A Randomized Controlled TrialNCT03628365