| Nicotinamide,vitamin B3, metabolic pathways in patients with early idiopathic parkinson's disease | Nicotinamide,vitamin B3, metabolic pathways in patients with early idiopathic parkinson's disease | EUCTR2004-005034-39-GB |
| Investigation of antipruritic effect of oral nicotinamide in uremic patients | Investigation of antipruritic effect of oral nicotinamide in uremic patients | IRCT201202068940N1 |
| skin saftey of Neutriderm Vitamin and Niacinamide Serum | A Clinical Study to Evaluate the skin Irritation Potential of Neutriderm Vitamin C15 percent Serum and Niacinamide 10 percent Serum on Healthy Human Volunteers - NIL | CTRI/2025/05/086628 |
| Effect of Nicotinamide in Friedreich's Ataxia | Pharmacodynamic Studies of a Histone Deacetylase Inhibitor in Friedreich's Ataxia | NCT01589809 |
| Effect of Vitamin B3 in Friedreich's ataxia | Pharmacodynamic Studies of a Histone Deacetylase Inhibitor in FRDA - The effect of Nicotinamide (Vitamin B3) in Friedreich’s ataxia | EUCTR2011-002744-27-GB |
| Prostate Radiotherapy with Oxygen Enhancement | A trial of Prostate Radiotherapy in Conjunction with Carbogen and Nicotinamide (PROCON) - PROCON | EUCTR2010-021886-63-GB |
| Randomised, double-blind, placebo controlled study to assess efficacy of oral nicotinamide (500mg daily) in the treatment and prevention of actinic keratoses. | Effect of nicotinamide versus placebo on numbers of actinic keratoses | ACTRN12610000689077 |
| Assessment of oral Nicotinamide effects on serum phosphorus in hemodialysis patients in Imam Khomeini and Golestan hospitals of Ahvaz in 2010 | Assessment of oral Nicotinamide effects on serum phosphorus in hemodialysis patients in Imam Khomeini and Golestan hospitals of Ahvaz in 2010 | IRCT138809172817N1 |
| Effects of CoQ10, melatonin, vitamin B groups, vitamin D. and probiotic on reducing COVID-19 symptoms during recovery | Evaluating the Effects of CoQ10, melatonin, vitamin B groups, vitamin D. and probiotic on reducing COVID-19 symptoms during recovery- A randomized double blind controlled Clinical Trial | IRCT20140804018677N21 |
| Randomised, double-blind, placebo controlled study to assess efficacy of oral nicotinamide in the treatment and prevention of actinic keratoses | Randomised, double-blind, placebo controlled study to assess efficacy of oral nicotinamide in the treatment and prevention of actinic keratoses | ACTRN12609000490279 |
| Comparaison du nicotinamide et du sevelamer hydrochloride sur le contrôle de la phosphatémie des hémodialysés chroniques - RENANIC | Comparaison du nicotinamide et du sevelamer hydrochloride sur le contrôle de la phosphatémie des hémodialysés chroniques - RENANIC | EUCTR2008-004673-17-FR |
| Safety Study of Nicotinamide to Treat Alzheimer's Disease | Efficacy of Nicotinamide for the Treatment of Alzheimer's Disease | NCT00580931 |
| Randomised, double-blind, placebo controlled study to assess efficacy of topical nicotinamide in the treatment and prevention of actinic keratosis. | Randomised, double-blind, placebo controlled study to assess efficacy of topical nicotinamide in the treatment and prevention of actinic keratosis. | ACTRN12607000428460 |
| An Investigator-initiated Trial to Assess the Effectiveness of Three Different Gummies (Curcumin Gummies, Vitamin C Gummies, and Vitamin B Complex Gummies) in Healthy Children | An Open-Label, Three-Arm, Parallel, Investigator-Initiated Trial of Three Different Gummies (Curcumin Gummies, Vitamin C Gummies, and Vitamin B Complex Gummies) in Healthy Children | NCT05775237 |
| Pyridoxine and Topical Urea/Lactic Acid-Based Cream in Preventing Hand-Foot Syndrome in Patients Receiving Capecitabine for Breast Cancer or Other Cancer | A Phase III Randomized, Placebo-controlled, Double-blind Trial to Determine the Effectiveness of a Urea/Lactic Acid-Based Topical Keratolytic Agent and Vitamin B-6 for Prevention of Capecitabine-Induced Hand and Foot Syndrome | NCT00296036 |
| To assess the effectiveness of three different gummies (Curcumin Gummies, Vitamin C Gummies, and Vitamin B Complex Gummies) in Healthy Children. | An Open-Label, Three-Arm, Parallel, Investigator-Initiated Trial of Three Different Gummies (Curcumin Gummies, Vitamin C Gummies, and Vitamin B Complex Gummies) in Healthy Children. | CTRI/2023/03/051016 |
| Pharmacokinetic Analysis of Nicotinamide Riboside | | NCT02300740 |
| ONTRAC: Effect of oral nicotinamide (vitamin B3) on incidence of nonmelanoma skin cancer and actinic keratoses: a randomised controlled trial (Oral Nicotinamide To Reduce Actinic Cancer) | Randomised double blinded placebo controlled trial to assess the effect of oral nicotinamide on numbers of new nonmelanoma skin cancers in immune competent adult patients with a history of at least two histologically confirmed nonmelanoma skin cancers within the previous five years | ACTRN12612000625875 |
| Nicotinamide as an Early Alzheimer's Disease Treatment | A Double-Blind-Randomized, Placebo-Controlled Adaptive Design Trial of Nicotinamide in Mild Cognitive Impairment Due to Alzheimer's Disease and Mild Alzheimer's Disease Dementia | NCT03061474 |
| 5-fluorouracil 5% compared to vitamin b3 in the treatment of precancerous skin changes | 5- fluorouracil 5% intermittent versus nicotinamide at the treatment cancerization skin field: a clinical trial | RBR-9rjg3g |
| Nicotinamide Adenine Dinucleotide and Skeletal Muscle Metabolic Phenotype | Nicotinamide Adenine Dinucleotide and Skeletal Muscle Metabolic Phenotype (NADMet) | NCT02950441 |
| The Effects of Nicotinamide Adenine Dinucleotide (NAD) on Brain Function and Cognition | The Effects of NAD on Brain Function and Cognition | NCT02942888 |
| Nicotinamide Riboside and Metabolic Health | Effects of Nicotinamide Riboside on Metabolic Health in (Pre)Obese Humans | NCT02835664 |
| Study to Evaluate the Effect of Nicotinamide Riboside on Immunity | Study to Evaluate the Effect of Nicotinamide Riboside on Immunity | NCT02812238 |
| """Pharmacokinetic Study of Nicotinamide Riboside""" | """Pharmacokinetic Study of Nicotinamide Riboside""" | NCT02689882 |
| Anti-inflammatory and antimicrobial effects of nicotinamide in bronchiectasis | The effect of nicotinamide on sputum cytokines in patients with bronchiectasis | ACTRN12615000359538 |
| Anticancer Activity of Nicotinamide on Lung Cancer | Randomized Double-blinded Comparative Trial to Study the Add-on Activity of Combination Treatment of Nicotinamide on Progression Free Survival for EGFR Mutated Lung Cancer Terminal Stage Patients Being Treated With Gefitinib or Erlotinib | NCT02416739 |
| Skin saftey test of TLC | A clinical study to evaluate the Skin Irritation Potential of TLC 20 percent Nano Vitamin C with Niacinamide on healthy human volunteers - NIL | CTRI/2025/03/082313 |
| The Effect of Vitamin B3 on Substrate Metabolism, Insulin Sensitivity, and Body Composition in Obese Men | The Effect of Nicotinamide Ribose (NR) on Substrate Metabolism, Insulin Sensitivity, and Body Composition in Obese Men - a Randomized, Placebo Controlled Clinical Trial | NCT02303483 |
| Phase I Study of Nicotinamide for Early Onset Preeclampsia | Phase I Study of Nicotinamide for Early Onset Preeclampsia | NCT02213094 |
| The COMBINE Study: The CKD Optimal Management With BInders and NicotinamidE | The COMBINE Study: The CKD Optimal Management With BInders and NicotinamidE | NCT02258074 |
| A study to assess the effects and safety of Sofinox Cream (Equivalent to Fusidic Acid 2.0% w/w) and Nicotinamide 3% w/w in volunteers with mild to moderate acne for 8 weeks | A single arm, open label controlled 8 weeks assessment study of the efficacy and safety of topical Sofinox cream (Sodium Fusidate IP equivalent to Fusidic Acid IP 2.0 % w/w) and Nicotinamide 3% w/w cream in volunteers with mild to moderate acne vulgaris | CTRI/2013/10/004103 |
| Efficacy and tolerability of nicotinamide as add-on therapy compared to placebo in dialysis-dependent patients with elevated phosphat level | Efficacy and tolerability of nicotinamide as add-on therapy compared to placebo in dialysis-dependent patients with hyperphosphatemia - NOPHOS Trial | EUCTR2013-000488-95-DE |
| Nicotinamide and innate immunity in patients with bronchiectasis | Enhanced innate immunity and killing of respiratory pathogens by nicotinamide in patients with bronchiectasis | ACTRN12613000699763 |
| To evaluate the effect and skin safety of 2 test products [cream containing Sodium Fusidate IP equivalent to Fusidic acid 0.25% w/w in the morning and cream containing Nicotinamide IP 4% w/w in the night] on subjects with moderate pimples on face | To evaluate the efficacy and in use skin safety of 2 test products [cream containing Sodium Fusidate IP equivalent to Fusidic acid 0.25% w/w in the morning and cream containing Nicotinamide IP 4% w/w in the night] on subjects with moderate facial acne. | CTRI/2013/06/003766 |
| Nicotinamide in the Treatment of Psoriasis | Evaluation of Topical Nicotinamide in Combination With Calcipotriol Compared With Calcipotriol Alone for the Treatment of Mild to Moderate Psoriasis. | NCT01763424 |
| Use of Tripterygium glycosides and Nicotinamide plus Minocycline for the Treatment of bullous pemphigoid: A multicenter,randomized and controlled clinincal trial | Guideline-oriented Research in the Management of Some Common and Severe Skin Diseases | ChiCTR-TRC-12003592 |
| Effect of oral nicotinamide (vitamin B3) on nonmelanoma skin cancer incidence and actinic keratoses in renal transplant recipients: a randomised controlled trial | Randomised double blinded placebo controlled trial to assess the effect of oral nicotinamide on numbers of new nonmelanoma skin cancers in immune suppressed adult renal transplant recipients with a history of at least two histologically confirmed nonmelanoma skin cancers within the previous 12 months | ACTRN12612000628842 |
| Study of Topical Niacinamide Serum Skin Application in Patients with Acne, Blemishes and Hyperpigmentation to check effecctiveness and tolerability | Effectiveness and Tolerability of Topical Niacinamide Serum Skin Application in Patients with Acne, Blemishes and Hyperpigmentation: An Observational Study - NIL | CTRI/2025/02/080872 |
| Effectiveness of Plum Serum in skin blemishes | A Single blind Clinical study to evaluate the effectiveness and safety of Plum rice water & niacinamide serum for SkinBrightening - NIL | CTRI/2023/12/060475 |
| Check Efficacy of 3% Niacinamide & Rice Water Toner for skin Brightening | A Clinical Study to Evaluate the Efficacy of 3% Niacinamide & Rice Water Toner for skin Brightening - NIL | CTRI/2025/02/080241 |
| Molecular Effects of Vitamin B3 (Niacinamide) in Acute Kidney Injury | | NCT02701127 |
| Pilot Study of Niacinamide in Polycystic Kidney Disease (NIAC-PKD2) | Randomized, Controlled Pilot Study of Niacinamide in Polycystic Kidney Disease | NCT02558595 |
| Uncontrolled, Open Label, Pilot and Feasibility Study of Niacinamide in Polycystic Kidney Disease | Uncontrolled, Open Label, Pilot and Feasibility Study of Niacinamide in Polycystic Kidney Disease | NCT02140814 |
| A randomised control trial of the effect of Niacinamide on Fibroblast Growth factor 23 (FGF23) levels in Chronic Kidney Disease. | A randomised, double-blind, placebo-controlled trial to assess the effect of niacinamide on levels of Fibroblast Growth factor 23 (FGF23) in patients with chronic kidney disease stages 3b-4. | ACTRN12613001229763 |
| Clinical Trial of 4% Niacinamide Versus 0.05% Desonide for the Treatment of Axillar Hyperpigmentation | A Double Blind, Randomized Clinical Trial of 4% Niacinamide Versus 0.05% Desonide for the Treatment of Axillar Hyperpigmentation | NCT01542138 |
| Phase I Vorinostat in Combination With Niacinamide and Etoposide for Lymphoid Malignancies | Phase I Study of Vorinostat in Combination With Niacinamide, and Etoposide for the Treatment of Patients With Relapsed and Refractory Lymphoid Malignancies | NCT00691210 |
| A Pilot Clinical Trial of Pyruvate, Creatine, and Niacinamide in Progressive Supranuclear Palsy. | Energy Metabolism in Neurodegenerative Diseases: A Randomized, Double Blind, Placebo-Controlled Clinical Pilot Trial of Pyruvate, Creatine, and Niacinamide in Progressive Supranuclear Palsy. | NCT00605930 |
| The Effect of Oral Niacinamide on Plasma Phosphorus Levels in Peritoneal Dialysis Patients | The Effect of Oral Niacinamide on Plasma Phosphorus Levels in Peritoneal Dialysis Patients | NCT00508885 |
| The Effect of Oral Niacinamide on Serum Phosphorus Levels in Hemodialysis Patients | The Effect of Oral Niacinamide on Serum Phosphorus Levels in Hemodialysis Patients | NCT00316472 |
| The effect of oral vitamin D and vitamin B on Treatment of vitiligo | To compare the improvement of Non-segmental Vitiligo patients with topical PUVA-therapy alone, topical PUVA-therapy and oral vitamin D, topical PUVA-therapy and oral vitamin D and oral vitamin B. | IRCT2016100527404N4 |
| Vitamin B 12 in the treatment of chronic hepatitis C | The effect of vitamin B12 supplementation to the standard therapeutic regimen on sustained viral response in genotype 1 chronic HCV infection | IRCT201508064226N3 |
| Vitamin B-6 and Glutathione on Inflammation, Homocysteine, Oxidative Stress and Antioxidant Capacities | The Effects of Vitamin B-6 and Glutathione on Inflammatory Responses, Homocysteine Metabolism, Oxidative Stress and Antioxidant Capacities in Patients With Liver Cirrhosis or Hepatocellular Carcinoma | NCT02321579 |
| Ascorbic Acid Treatment in Congenital Glucocorticoids and Mineralocorticoids Deficiency Due to NNT Mutation | Ascorbic Acid Treatment for Patients With Combined Mineralocorticoid and Glucocorticoid Deficiency Secondary to Nicotinamide Nucleotide Transhydrogenase Mutation | NCT02838472 |
| Healthy Combine Study | Short-Term Effects of Nicotinamide and Lanthanum Carbonate on Phosphorus Homeostasis in Healthy Volunteers | NCT03136705 |
| Parallel-group comparative study to evaluate the effect of high-dose nicotinamide mononucleotide (NMN) on aging | Randomized, double-blind, placebo-controlled parallel-group comparative study to evaluate the effect of high-dose nicotinamide mononucleotide (NMN) on aging | JPRN-jRCTs031220373 |
| Folate Activity Cognition Trial | The effects of physical activity and vitamin B supplementation on cognitive functioning and psychosocial health of older persons with mild cognitive impairment | ISRCTN19227688 |
| The use of a Vitamin B nutraceutical to treat migraine | A study in migraine sufferers using B group vitamins in a double-blind placebo controlled study to determine effective doses for reduction of migraine morbidity. | ACTRN12612001195842 |
| THE EFFECT OF NIACINAMIDE SUPPLEMENTATION ON PHOSPHATE CONCENTATIONS IN DIALYSIS PATIENTS. | THE EFFECT OF NIACINAMIDE SUPPLEMENTATION ON PHOSPHATE CONCENTATIONS IN DIALYSIS PATIENTS. - the DiaNia-study | NL-OMON41924 |
| A study on how to lighten dark spots on gums using microneedling with and without topically applied niacinamide, compared to the traditional scalpel method | Gingival depigmentation using Microneedling technique with and without topical application of Niacinamide versus the conventional scalpel technique: A randomized controlled clinical trail - NIL | CTRI/2025/02/080441 |
| DNA Methylation in Malar Melasma and Its Change by Sunscreen, Retinoic Acid and Niacinamide. | DNA Methylation in Malar Melasma and Its Change by Sunscreen, Retinoic Acid and Niacinamide. | NCT03392623 |
| A Study of 99mTc-3PRGD2 Injection in Healthy Volunteers | Phase I Open Label Trial of Pharmacokinetics and Safety of 99mTc Niacinamide Polyethylene Glycol Bicyclic RGD Peptide (99mTc-3PRGD2) Injection in Healthy Volunteers | NCT03974685 |
| user rating of Plum Niacinamide Tinted Sunscreen | In-use test to study the user rating for Plum Niacinamide Tinted Sunscreen - NIL | CTRI/2025/01/079374 |
| Sensorial test of 10 percent Niacinamide face serum with 3 marketed products | A Sensorial Assessment of the 10 percent Niacinamide face serum in comparison with the 3 marketed products - NIL | CTRI/2024/12/078051 |
| Cleansing potential of 2% Niacinamide and Rice Water Face Wash | To study the effectiveness of Plum 2% Niacinamide & Rice Water Face Wash for skin brightening, hydration and softness - NIL | CTRI/2024/11/077325 |
| effectiveness of Plum 2% Niacinamide & Rice Water Face Wash | To study the effectiveness of Plum 2 percent Niacinamide & Rice Water Face Wash for skin brightening, hydration and softness - NIL | CTRI/2024/11/076661 |
| Brightening and Pore Refining Activity of Asaya Serum | A Consumer study to check the Brightening and Pore Refining Activity of Asaya 10 percent VitaminC and 5percent Niacinamide Serum. - NIL | CTRI/2024/10/075473 |
| sebum reduction & blemishes control activity | A Consumer study to check the a sebum reduction and blemishes control activity of Asaya 10 percent Niacinamide and 1 percent Alpha Arbutin Serum - NIL | CTRI/2024/10/074954 |
| Non-Comedogenic of Plum 3% Niacinamide Toner. | A clinical study to Evaluation Of Non-Comedogenic Effect of Plum 3% Niacinamide Toner. - NIL | CTRI/2024/09/074157 |
| Non-Comedogenic Effect of Plum Rice water and Niacinamide clear moisture gel cream. | A clinical study to Evaluation Of Non-Comedogenic Effect of Plum Rice water and Niacinamide clear moisture gel cream. - NIL | CTRI/2024/09/074008 |
| Assessment of Niacinamide Cosmetic Product Efficacy in Model of Irritant Contact Dermatitis | Randomized Controlled Trial of Niacinamide Cosmetic Product Efficacy in Model of Irritant Contact Dermatitis | NCT06331390 |
| Topical niacinamide in graded concentrations on skin health metrics in Indian women | Efficacy of topical niacinamide in graded concentrations on skin health metrics in Indian women-A randomized, parallel-group, clinical trial. - NA | CTRI/2024/02/063151 |
| Effectiveness of Plum clear moisture gel cream in skin blemishes | A Single blind Clinical study to evaluate the effectiveness and safety of PlumRice water & Niacinamide clear moisture gel cream for Skin Brightening. - NIL | CTRI/2024/01/061140 |
| Study on the Effectiveness of an Emollient Cream Containing Pre and Postbiotic and Niacinamide 4% in the Treatment of Skin Xerosis and Itching in Oncological Patients Treated with Anti-EGFR | Studio Sulla Efficacia Di Una Crema Emolliente Contenente Pre E Postbiotici E Niacinamide 4% Nel Trattamento Della Xerosi Cutanea E Del Prurito in Pazienti Oncologici in Trattamento Con Anti-EGFR | NCT06868771 |
| Clinical assessment of the efficacy of topical nano-formulation of tranexamic acid/niacinamide in melasma | Clinical assessment of the efficacy of tranexamic acid-niacinamide loaded niosome in comparison to tranexamic acid-niacinamide and hydroquinone conventional creams in melasma | IRCT20220609055116N1 |
| Effectiveness of Topical Niacinamide, Zinc and Magnesium combined with Doxycycline in the treatment of Acne Vulgaris in Thai female | Effectiveness of Topical Niacinamide, Zinc and Magnesium combined with Doxycycline in the treatment of Acne Vulgaris in Thai female | TCTR20230120002 |
| A national multicenter, double-blind, randomized, controlled clinical study of the effect of nicotinamide single nucleotide (NMN) intervention on people with chronic insomnia | A national multicenter, double-blind, randomized, controlled clinical study of the effect of nicotinamide single nucleotide (NMN) intervention on people with chronic insomnia | ChiCTR2200058001 |
| Clinical trial to study the role of Vitamin B3 in recovery of patients having Acute Kidney Injury | Niacinamide and renal recovery in community acquired AKI: feasibility study | CTRI/2022/03/040892 |
| The Effectiveness and Safety of Niacinamide 4% and Virgin Coconut Oil 30% for Secondary Prevention of Occupational Hand Dermatitis | Comparison of the Effectiveness and Safety Between Moisturizing Cream Containing Niacinamide 4% and Virgin Coconut Oil 30% for Secondary Prevention of Occupational Hand Hermatitis in Intensive Care Unit Nurses: a Double Blind Randomized Clinical Trial | NCT04218500 |
| Nicotinamide in Non-Alcoholic Fatty Liver Disease Patients | Evaluation of Efficacy and Safety of Nicotinamide in Non-Alcoholic Fatty Liver Disease Patients | NCT03850886 |
| Nicotinamide Riboside in Systolic Heart Failure | Safety and Tolerability of the Nutritional Supplement, Nicotinamide Riboside, in Systolic Heart Failure | NCT03423342 |
| N-DOSE AD: a Dose Optimization Trial of Nicotinamide Riboside in Alzheimer's Disease | N-DOSE AD: a Dose Optimization Trial of Nicotinamide Riboside in Alzheimer's Disease | NCT05617508 |
| The Effects of Nicotinamide Riboside Supplementation on Brain NAD+/NADH Ratio and Bioenergetics | The Effects of Nicotinamide Riboside Supplementation on Nicotinamide Adenine Dinucleotide (NAD+/NADH) Ratio and Bioenergetics | NCT03151707 |
| Nicotinamide Riboside Supplementation and Exercise Training to Promote Healthy Longevity | Boosting the NAD+ Levels in Older Individuals Via Nicotinamide Riboside Supplementation and Exercise Training to Promote Metabolic Health | NCT06425042 |
| IV Administration of ChromaDex's Niagen® as Compared to NAD+ | The Effects of IV Administration of ChromaDex's Niagen®, Nicotinamide Riboside Chloride as Compared to IV Administration of NAD+: A Randomized, Placebo Controlled Clinical Trial | NCT06382688 |
| NRM on Vascular Perfusion in Healthy Adults | The Effect of Oral Nicotinamide Riboside on Systemic Vascular Perfusion in Healthy Adults: A Critical Foundation of Cerebrovascular Health, Cardiovascular Health, and Healthy Aging | NCT06345443 |
| Ataxia-telangiectasia: Treating Mitochondrial Dysfunction With Nicotinamide Riboside | Single Arm Open-label Clinical Trial in Ataxia-telangiectasia to Test the Effects of Nicotinamide Riboside on Ataxia Scales, Immune Function, and Neurofilament Light Chain. | NCT06324877 |
| Nicotinamide Riboside (NR) to Treat Moyamoya-like Cerebrovascular Disease in Smooth Muscle Dysfunction Syndrome (SMDS) | Nicotinamide Riboside (NR) to Treat Moyamoya-like Cerebrovascular Disease in Smooth Muscle Dysfunction Syndrome (SMDS) | NCT06280482 |
| Preliminary Clinical Study of NMN Intervention in Mild Ulcerative Colitis | A Single-center, Randomized, Double-blind, Placebo-controlled, Parallel-group Clinical Trial of Nicotinamide Mononucleotide in the Treatment of Mild Ulcerative Colitis | NCT06214078 |
| Protective Effect of Nicotinamide Riboside Against Acetaminophen Toxicity | Protective Effect of Nicotinamide Riboside Against Acetaminophen Toxicity | NCT06214468 |
| To Investigate the change in oral bioavailability of Nicotinamide Mononucleotide (NMN, 500mg) when 5mg Bioperine is added to NMN 500mg in normal healthy volunteers. | A pilot two arm, two period, cross over, open label, Single-centre, comparative trial to Investigate the change in oral bioavailability of Nicotinamide Mononucleotide (NMN, 500mg) when 5mg Bioperine is added to NMN 500mg in normal healthy volunteers. - NIL | CTRI/2023/11/059982 |
| The NADage Study: Nicotinamide Riboside Replenishment Therapy Against Functional Decline in Aging | The NADage Study: a Randomized Double-blind Trial of NAD Replenishment Therapy on Aging | NCT06208527 |
| Effect of Nicotinamide Riboside on Ketosis, Fat Oxidation & Metabolic Rate | Effect of Nicotinamide Riboside on Ketosis, Fat Oxidation &Amp;Amp;Amp;Amp; Metabolic Rate | NCT06044935 |
| Double-blind Placebo Controlled Study to Evaluate the Effect of NAD+ Boosting With Nicotinamide Riboside on Immunometabolism and Immunity in Systemic Lupus Erythematosus | Double-blind Placebo Controlled Study to Evaluate the Effect of NAD+ Boosting With Nicotinamide Riboside on Immunometabolism and Immunity in Systemic Lupus Erythematosus | NCT06032923 |
| Nicotinamide (vitamin B3) – diet and exercise in the context of prolonged outpatient rehabilitation – a randomized, placebo-controlled, double-blind pilot study | Nicotinamide (vitamin B3) – diet and exercise in the context of prolonged outpatient rehabilitation – a randomized, placebo-controlled, double-blind pilot study | DRKS00031318 |
| Nicotinamide Chemoprevention for Keratinocyte Carcinoma in Solid Organ Transplant Recipients - Pivotal Trial | Nicotinamide Chemoprevention for Keratinocyte Carcinoma in Solid Organ Transplant Recipients: a Multicentre, Pragmatic Randomized Trial | NCT05955924 |
| Tolerance and Efficacy Nicotinamide (vitamin B3) in Dominant Optic Atrophy OPA1 | Pilot Study of Tolerance and Efficacy Nicotinamide (vitamin B3) in Dominant Optic Atrophy OPA1 | NCT06007391 |
| Effect of nicotinamide riboside supplementation in dilated cardiomyopathy patients to CERP, Chromadex Inc. USA | Effect of nicotinamide riboside supplementation in dilated cardiomyopathy patients | CTRI/2023/04/051385 |
| Metabolic Changes Induced by NMN in Healthy Subjects With Acute Binge Drink | Effect of ß-nicotinamide Mononucleotide Intervention on Healthy Young Subjects With Acute Binge Drink: a Double-blinded, Randomized, Crossover Trial | NCT05882214 |
| Efficacy of Nicotinamide on Retinal Ganglion Cell Functions in Glaucoma Patients | Efficacy of Nicotinamide on Retinal Ganglion Cell Functions in Glaucoma Patients : Clinical Trial, Cross-over Design, Double-blind, Placebo-control, Randomized, Single-center Study | NCT06078605 |
| Effect of nicotinamide adenine dinucleotide on cardiac function in patients with ischemic cardiomyopathy complicated with heart failure | Effect of nicotinamide adenine dinucleotide on cardiac function in patients with ischemic cardiomyopathy complicated with heart failure | ChiCTR2200059169 |
| Topical Nicotinamide in Treatment of DLE | Efficacy and Safety of Topical Nicotinamide in Treatment of Discoid Lupus Erythematosus | NCT05362188 |
| Effect of nicotinamide adenine dinucleotide on cardiac function after primary PCI in patients with acute ST segment elevation myocardial infarction | Effect of nicotinamide adenine dinucleotide on cardiac function after primary PCI in patients with acute ST segment elevation myocardial infarction | ChiCTR2200059333 |
| Comparison of 30% Metformin and 2% Nicotinamide Lotion With Kligman Formula in the Treatment of Melasma | Comparison of 30% Metformin and 2% Nicotinamide Lotion With Kligman Formula in the Treatment of Melasma | NCT05790577 |
| Benefits of Nicotinamide Riboside Upon Cognition and Sleep | The Benefits of Nicotinamide Riboside Upon Cognition and Sleep in Older Veterans | NCT05500170 |
| Nicotinamide Riboside in Ulcerative Colitis | Nicotinamide Riboside in Ulcerative Colitis | NCT05561738 |
| Nicotinamide Supplementation Improves Physical Performance in Older Adults at Risk of Falls | Nicotinamide Supplementation Improves Physical Performance in Older Adults at Risk of Falls: a Pilot Randomized Clinical Trial | NCT06465602 |
| N-DOSE: A Dose Optimization Trial of Nicotinamide Riboside in Parkinson's Disease | N-DOSE: A Dose Optimization Trial of Nicotinamide Riboside in Parkinson's Disease | NCT05589766 |
| Nicotinamide and Pyruvate for Open Angle Glaucoma: A Randomized Clinical Study | Nicotinamide and Pyruvate for Open Angle Glaucoma: A Randomized Clinical Study | NCT05695027 |
| Improved Skin Whitening Outcomes Associated With Nicotinamide Fortified Consumption in 30 to 50- Year-old Women | Improved Skin Whitening Outcomes Associated With Nicotinamide Fortified Consumption in 30 to 50-Year-old Women, a Double Blind, Control and Randomized Study | NCT05696938 |
| Pilot Trial of Supplemental Vitamin A and Nicotinamide | Pilot Trial of Supplemental Vitamin A and Nicotinamide and Levels of Blood Vitamin A and Nicotinamide | NCT05702398 |
| Effect and safety of 5% nicotinamide cream in the treatment of actinic keratosis | Efficacy and safety of 5% nicotinamide cream in stabilizing the skin field cancerization: a randomized, double blind, placebo-controlled clinical trial | RBR-6m7tyhf |
| Mental Intervention and Nicotinamide Riboside Supplementation in Long Covid | The Efficacy and Safety of a Mental Intervention Program vs. Usual Care and Nicotinamide Riboside (NR) vs. Placebo for Improving Health-related Quality of Life in Long Covid: A 2 x 2 Factorial Randomized Controlled Trial | NCT05703074 |
| Nicotinamide Riboside and Prevention of Cancer Therapy Related Cardiac Dysfunction in Breast Cancer Patients | Effect of Nicotinamide Riboside on Myocardial and Skeletal Muscle Injury and Function in Patients With Metastatic Breast Cancer Receiving Anthracyclines | NCT05732051 |
| A Study to Evaluate Vitamin B3 Derivative to Treat Mitochondrial Myopathy | Randomized, Double-blinded, Placebo-controlled Study Evaluating the Efficacy of Nicotinamide Riboside (NR) - a Vitamin B3 Derivative - for Treatment of Mitochondrial Myopathy Disorder | NCT05590468 |
| Study of the Efficacy and Safety of Nicotinamide in Patients with Diabetes Mellitus Type 2 and Liver Fibrosis (NICOFIB) | Randomized, Double-blind, Placebo-controlled Study of the Efficacy and Safety of Nicotinamide in Patients with Diabetes Mellitus Type 2 and Liver Fibrosis (NICOFIB) | NCT06599918 |
| Impact of Nicotinamide Riboside (NR) on Kidney Function in Patients Undergoing Cardiac Surgery | Impact of Nicotinamide Riboside (NR) on Kidney Function in Patients Undergoing Cardiac Surgery.A Randomized Controlled Pilot Study | NCT06521307 |
| NAD Supplementation and Vascular Health in PAD | The Effect of Nicotinamide Adenine Dinucleotide (NAD) Supplementation on Systemic Vascular Health in Peripheral Artery Disease | NCT06534944 |
| No-tox Vs. Retinoid (Tretinoin) Study: Comparison of the wrinkle reduction performance of a cosmeceutical non-toxin based wrinkle-reducing serum against a pharmaceutical prescription-grade retinol | A randomised, controlled comparative study the wrinkle reduction benefits of No-Tox, a plukenetia/niacinamide/plankton-based topical cosmeceutical formulation vs. 0.5 mg (0.05% w/w) tretinoin, a pharmaceutical prescription-strength topical retinoic acid formulation in healthy adults | ACTRN12621001735842 |
| The benefit of Nicotinamide + Vitamin C + Hyaluronic Acid, compared to Hydroquinone in the treatment of Melasma | Efficacy and safety topical Nicotinamide 10%, associated with VCPMG 5% and Hyaluronic Acid 5%, compared to Hydroquinone 4% tested in Brazilian women with Melasma: a double-blind, randomized and controlled trial | RBR-4mkfmr8 |
| the Effect of Vitamin B 1 on Menstrual Pattern After Insertion of the IUD. | the Effect of Vitamin B 1 on Menstrual Pattern After Insertion of the IUD. | NCT05971680 |
| Effect of Vitamin B addition to Lidocaine for Myofascial Trigger Point Injection in Neck and Upper Back Muscles | Effect of Vitamin B addition to Lidocaine for Myofascial Trigger Point Injection in Neck and Upper Back Muscles | TCTR20190308005 |
| Ureteric Visualization: Vitamin B Vs 5% Dextrose in Water | Optimal Ureteric Visualization At the Time of Pelvic Reconstructive Surgery: Vitamin B Versus 5% Dextrose in Water | NCT03089671 |
| Analgesic and Anti-inflamatory Effect of Vit. B | The Analgesic and Anti-inflamatory Effect of Vitamin B Versus Vitamin C Infusion in Patients Undergoing Laparoscopic Cholecystectomy ; a Randomized Controlled Trial | NCT06857734 |
| Nicotinamide Riboside With and Without Resveratrol to Improve Functioning in Peripheral Artery Disease | Nicotinamide Riboside With and Without Resveratrol to Improve Functioning in Peripheral Artery Disease: The NICE Trial | NCT03743636 |
| Comparing the postsurgical pain relieving effects of three groups of drugs in patient of open inguinal hernia repair posted under regional anaesthesia. | Comparative study of preoperative oral pregabalin alone,pregabalin with dexamethasone and pregabalin with Vitamin B complex for postoperative analgesic requirement in open inguinal hernia repair under subarachanoid block. | CTRI/2018/04/013293 |
| Effectiveness of vitamin B and E in reducing pain | Comparing the effectiveness of vitamin B and E with diclofenac in reducing pain from osteoarthritis of the knee | IRCT201408306480N7 |
| supplementation in COVID-19 | Impact of vitamin B, A, D, E, C supplementation on improvement and mortality rate in patients with COVID-19 admitted in intensive care unit | IRCT20200319046819N1 |
| Comparing nicotinamide ribose with vitamin E to improve fertility in elderly women: a single-center, randomized, parallel trial | Comparing nicotinamide ribose with vitamin E to improve fertility in elderly women: a single-center, randomized, parallel trial | ChiCTR2200056972 |
| A Study to See Whether Taking a Mix of Vitamins Can Help Adults Recover Better After Surgery for Carpal Tunnel Syndrome | Effect of Oral Alpha-Lipoic Acid, Vitamin E, and Vitamin B Combination on Symptoms and Function in Carpal Tunnel Syndrome Following Carpal Tunnel Surgery | NCT07312123 |
| Effectiveness of methylcobalamin and alpha lipoic acid in diabetic neuropathy. | Comparison of effectiveness of methylcobalamin, alpha lipoic acid and vitamin B groups with placebo to control diabetic neuropathy syndrome in type 2 diabetes. | IRCT20221122056577N1 |
| Comparisons of NAD Precursors for Neuroenhancement in Glaucoma Patients | Comparisons of Nicotinamide Adenine Dinucleotide (NAD) Precursors for Neuroenhancement in Glaucoma Patients | NCT06991712 |
| The Effects of Vitamin B-6 Status on Homocysteine, Oxidative Stress, One-carbon Metabolism and Methylation: Cross-section, Case-control, Intervention and Follow-up Studies in Colorectal Cancer | | NCT01426490 |
| The HF-AF ENERGY Trial: Attenuate atrial fibrillation with nicotinamide riboside (niagen) | The HF-AF ENERGY Trial: Attenuate atrial fibrillation with nicotinamide riboside (niagen) - The HF-AF ENERGY Trial | NL-OMON52394 |
| Effect of the Combination of Pterostilbene Cocrystal With Silybin and Nicotinamide Riboside on Exercise-Induced Oxidative Stress | Effect of the Combination of Pterostilbene Cocrystal With Silybin and Nicotinamide Riboside on High-Intensity Exercise-Induced Oxidative Stress: A Randomized, Crossover, Placebo-Controlled, Triple-Blind Study | NCT07024966 |
| A Single Dose Study Of Investigational Product Containing Nicotinamide Mononucleotide (NMN), In Healthy, Adult, Human Subjects Under Fasting Conditions. | A Double-Blind, Randomized, Single Dose, Two-Treatment, Two-Period, Two-Way Crossover, Oral Bioavailability Study Of Investigational Product Containing Nicotinamide Mononucleotide (NMN), In Healthy, Adult, Human Subjects Under Fasting Conditions. - nil | CTRI/2025/03/081830 |
| Zinc and Nicotinamide Riboside for Idiopathic Pulmonary Fibrosis | Feasibility of a Decentralized Double-Blind Randomized Controlled Trial of Zinc and Nicotinamide Riboside for the Treatment of Idiopathic Pulmonary Fibrosis | NCT06567717 |
| Evaluation of Beta NMN pills in slowing the aging process in patients with heart disease | Evaluation of Epigenetic aging and its modulation by Beta-Nicotinamide Mononucleotide [Beta-NMN] in patients diagnosed with Coronary Artery Disease - NILL | CTRI/2024/08/073020 |
| Nicotinamide Riboside Oral Supplementation in Macula Off Retinal Detachment | A Randomised Double-Masked Placebo-Controlled Trial of Nicotinamide Riboside Oral Supplementation in Macula Off Retinal Detachment | NCT06587945 |
| Evaluation of anti-aging potential of Beta-Nicotinamide Mononucleotide(NMN) tablets in Heart Disease patients. | Effectiveness of Beta-Nicotinamide Mononucleotide (NMN) as an Anti-agingsupplement for patients with Coronary Artery Disease- A Pilot Study - NIL | CTRI/2024/09/074372 |
| The Effect of Nicotinamide on the Clinical Outcome of Rheumatoid Arthritis Patients | The Effect of Nicotinamide on the Clinical Outcome of Rheumatoid Arthritis Patients | NCT06640309 |
| Nicotinamide Supplementation in Glaucoma | Targeting Metabolic Insufficiency (TAMING) Glaucoma Study : a 2-year Multi-centre, Double-masked, Randomised, Placebo-controlled Trial of Nicotinamide (Vitamin B3) Supplementation in Glaucoma | NCT06731582 |
| NADream: Effects of Nicotinamide Adenine Dinucleotide Supplementation on Sleep Quality in Healthy Individuals | NADream: Effects of Nicotinamide Adenine Dinucleotide Supplementation on Sleep Quality in Healthy Individuals: A Randomized Controlled Pilot Study | NCT06971224 |
| A Clinical Study of NAD in the Treatment of Immune Thrombocytopenia | A Prospective, One-arm and Open Clinical Study to Assess Safety and Efficacy of Nicotinamide Adenine Dinucleotide in the Treatment of Primary Immune Thrombocytopenia | NCT06776510 |
| Efficacy and tolerance of nicotinamide supplementation during acute kidney injury: a prospective randomized double-blind trial | Efficacy and tolerance of nicotinamide supplementation during acute kidney injury: a prospective randomized double-blind trial | CTIS2023-508664-30-00 |
| A randomized controlled trial for exploring the efficacy of folic acid and Vitamin B in lowering hyperhomocystinemia in patients with chronic renal failure and improving left ventricular hypertrophy | A randomized controlled trial for exploring the efficacy of folic acid and Vitamin B in lowering hyperhomocystinemia in patients with chronic renal failure and improving left ventricular hypertrophy | ChiCTR-IPR-17013161 |
| Study on the relative bioavailability of liposome ß - nicotinamide mononucleotide | Study on the relative bioavailability of liposome ß - nicotinamide mononucleotide | ChiCTR2500096819 |
| The NAD-HD Study: A Study to Investigate Efficacy and Safety of Nicotinamide Riboside Compared With Placebo in Huntington's Disease | The NAD-HD Study: A Parallel-group, Phase 2, Double-blind Study to Investigate the Efficacy and Safety of Oral Nicotinamide Riboside Compared With Placebo in Participants Aged 18 to 80 Years With Huntington's Disease | NCT06853743 |
| A Pilot Study to Assess the Efficacy and Safety of Folic Acid and/or Vitamin B Complex on Hepatitis C Infected Patients Treated With Pegylated Interferon and Ribavirin. | A Pilot Study to Assess the Efficacy and Safety of Folic Acid and/or Vitamin B Complex on Hepatitis C Infected Patients Treated With Pegylated Interferon and Ribavirin. | NCT02150291 |
| Effect of vitamin B treatment on brain damage and cognition in HIV-infected individuals with high levels of homocysteine in blood. | Effect of vitamin B substitution on plasma NFL and neurocognitive performance in HIV-infected individuals with increased plasma homocysteine | EUCTR2015-004311-20-SE |
| Association study between specific metabolic/genomic profiles and chemopreventive efficacy of nicotinamide | Multicenter, interventional, single-arm, phase IV study on specific metabolic and genomic profiles as predictors of nicotinamide efficacy in cutaneous squamous cell carcinoma prevention - NAMCHEM: NicotinAMide CHEMoprevention | EUCTR2018-000743-66-IT |
| Effect of oral nicotinamide (vitamin B3) on skin cancer incidence and actinic keratoses in kidney, liver, heart and lung transplant recipients: a randomised controlled Phase 3 trial | EFFECT OF ORAL NICOTINAMIDE ON NON-MELANOMA SKIN CANCER INCIDENCE AND ACTINIC KERATOSES IN RENAL, HEPATIC, HEART AND LUNG TRANSPLANT RECIPIENTS: A RANDOMISED CONTROLLED TRIAL | ACTRN12617000599370 |
| Replenishing a vital molecule in stiff heart failure patients and examining effect on heart stiffness, blood pressure, and exercise tolerance | Replenishing cardiac levels of oxidized nicotinamide adenine dinucleotide with precursor nicotinamide riboside in patients with heart failure with preserved ejection fraction, and determination of the effect on cardiac diastolic function, exercise tolerance, blood pressure, and glucose tolerance | ACTRN12622000372785 |
| Nicotinamide in Glaucoma (NAMinG): A Randomised, Placebo-controlled, Multi-centre, Phase III Trial | A Phase III, Double-masked, Randomised, Placebo-controlled Trial Investigating the Safety and Efficacy of Nicotinamide (NAM) to Slow Visual Field Loss in Adults With Open-angle Glaucoma | NCT05405868 |
| A Study of Nicotinamide With Oral Tetrahydrouridine and Decitabine to Treat High Risk Sickle Cell Disease | Proof-of-concept Study of Nicotinamide and Oral Tetrahydrouridine (THU) and Decitabine to Treat High Risk Sickle Cell Disease | NCT04055818 |
| A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL-GROUP, MULTICENTRE STUDY OF THE EFFICACY AND SAFETY OF NICOTINAMIDE IN PATIENTS WITH FRIEDREICHS ATAXIA. | A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL-GROUP, MULTICENTRE STUDY OF THE EFFICACY AND SAFETY OF NICOTINAMIDE IN PATIENTS WITH FRIEDREICHS ATAXIA. - NICOFA | EUCTR2017-002163-17-AT |
| Nicotinamide Riboside Supplementation for Treating Arterial Stiffness and Elevated Systolic Blood Pressure in Patients With Moderate to Severe CKD | Nicotinamide Riboside Supplementation for Treating Arterial Stiffness and Elevated Systolic Blood Pressure in Patients With Moderate to Severe CKD | NCT04040959 |
| Evaluation of Nicotinamide Riboside in Prevention of Small Fiber Axon Degeneration and Promotion of Nerve Regeneration | Evaluation of Nicotinamide Riboside in Prevention of Small Fiber Axon Degeneration and Promotion of Nerve Regeneration | NCT03912220 |
| Nicotinamide riboside as a neuroprotective therapy for glaucoma – A randomized controlled trial | Nicotinamide riboside as a neuroprotective therapy for glaucoma – A randomized controlled trial | ChiCTR1900021998 |
| Exporatory clinical study for preeclampsia with oral nicotinamide | Exporatory clinical study for newly developed drug therapy for preeclampsia with oral nicotinamide | JPRN-jRCTs021180005 |
| Effects of nicotinamide riboside (vitamin B3) in patients with Ataxia Telangiectasia | Effects of nicotinamide riboside (vitamin B3) in patients with Ataxia Telangiectasia - Vitamine B3 in A-T | NL-OMON48100 |
| Effects of Vitamin B3 Derivative Nicotinamide Riboside (NR) in Bone, Skeletal Muscle and Metabolic Functions in Aging | A Randomized, Double-blinded, Placebo-controlled Study to Evaluate the Effects of Vitamin B3 Derivative Nicotinamide Riboside (NR) in Bone, Skeletal Muscle and Metabolic Functions in Aging | NCT03818802 |
| Nicotinamide Riboside for Treating Elevated Systolic Blood Pressure and Arterial Stiffness in Middle-aged and Older Adults | Nicotinamide Riboside Supplementation for Treating Elevated Systolic Blood Pressure and Arterial Stiffness in Middle-aged and Older Adults | NCT03821623 |
| Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni Syndrome | Exploratory Study of Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni Syndrome | NCT03789175 |
| Skin Cancer Prevention With Nicotinamide in Transplant Recipients - Pilot Trial | Nicotinamide Chemoprevention for Keratinocyte Carcinoma in Solid Organ Transplant Recipients: A Pilot, Placebo-controlled, Randomized Trial | NCT03769285 |
| Effect of Nicotinamide Riboside and Pterostilbene Supplementation on Muscle Regeneration in Elderly Humans | Effect of Nicotinamide Riboside and Pterostilbene Supplementation on Muscle Regeneration in Elderly Humans - A Randomized, Placebo-controlled, Clinical Trial | NCT03754842 |
| Nicotinamide Riboside in LVAD Recipients | Pilot Study of Preoperative Nicotinamide Riboside (Vitamin B3) Supplementation in Patients Undergoing Elective Left Ventricular Assist Device (LVAD) Implantation | NCT03727646 |
| Effects of nicotinamide riboside on metabolic health in obese humans | Effects of nicotinamide riboside on metabolic health in obese humans - Nicotinamide riboside and metabolic health | NL-OMON47018 |
| A study to investigate Vitamin B3 concentrations in the joint after intake | Assessing penetration of high dose Nicotinamide (Vitamin B3) in synovial fluid - B-Vit in the joint | EUCTR2018-002245-11-NL |
| NR in Chemo-induced Peripheral Neuropathy | Nicotinamide Riboside (NR) in Paclitaxel-induced Peripheral Neuropathy | NCT03642990 |
| Efficacy and Tolerability of Nicotinamide Plus Cream for Moderate Acne Vulgaris in Indonesia | Efficacy and Tolerability of Nicotinamide Plus Cream for Moderate Acne Vulgaris in Indonesia: A Multicenter Clinical Trial | NCT03626298 |
| The Effect of Vitamin B3 Supplementation in Glaucoma | A Prospective Study on the Effect of Nicotinamide Supplementation on Ocular Function and Structure in Glaucoma | ACTRN12617000809336 |
| A study to investigate the safety of additional treatment with Vitamin B3 in children with Juvenile Idiopathic Arthritis (JIA) | Modulating regulatory T cell function in JIA with Vitamin B3 (nicotinamide) treatment | NL-OMON23481 |
| Nicotinamide Treatment for Lupus-associated Skin Lesions in Lupus Erythematosus | An Open-label Study for Assessing the Efficacy and Safety of Nicotinamide Treatment for Lupus-associated Skin Lesions in Patients With Cutaneous Lupus Erythematosus or Systemic Lupus Erythematosus | NCT03260166 |
| A study to investigate the safety of additional treatment with Vitamin B3 in children with Juvenile Idiopathic Arthritis (JIA) | Modulating regulatory T cell function in JIA with Vitamin B3 (nicotinamide) treatment - B-Vit in JIA | EUCTR2016-003643-10-NL |
| Exporatory clinical study for newly developed drug therapy for preeclampsia with oral nicotinamide | Exporatory clinical study for newly developed drug therapy for preeclampsia with oral nicotinamide - Exporatory clinical study for preeclampsia with oral nicotinamide | JPRN-UMIN000029418 |
| Modulating regulatory T cell function in Juvenile Idiopathic Arthritis with Vitamin B3 (nicotinamide): a phase I/II trial focusing on safety and feasibility aspects in children with JIA. | Modulating regulatory T cell function in Juvenile Idiopathic Arthritis with Vitamin B3 (nicotinamide): a phase I/II trial focusing on safety and feasibility aspects in children with JIA. - B-Vit in JIA trial | NL-OMON45620 |
| Protection From Acute Kidney Injury (AKI) With Basis™ Treatment | A Phase II, Randomized, Double-blinded, Placebo-controlled Clinical Trial to Evaluate the Efficacy of BASIS™ (Nicotinamide Riboside and Pterostilbene) Treatment for Kidney Protection in Patients Treated by Complex Aortic Aneurysm Repair and Aortic Arch Reconstruction | NCT04342975 |
| Nicotinamide Riboside and Mitochondrial Biogenesis | The Role of Nicotinamide Riboside in Mitochondrial Biogenesis | NCT03432871 |
| Pharmacokinetics of orally-administered Nicotinamide Powder 10% Zonne and its NAD+ pathway metabolites | Pharmacokinetics of orally-administered Nicotinamide Powder 10% Zonne and its NAD+ pathway metabolites - Pharmacokinetics of vitamin B3 and NAD+ metabolites in blood and urine | JPRN-UMIN000031610 |
| Effects of Nicotinamide Riboside on Metabolism and Vascular Function | Effects of Nicotinamide Riboside on Metabolism and Vascular Function | NCT03501433 |
| A Study by ChromaDex to Assess the Effects of TRU NIAGEN on Cognitive Function, Mood and Sleep in Older Adults | A Randomized, Double-Blind, Crossover Study to Assess the Effects of Nicotinamide Riboside on Cognitive Function, Mood and Sleep in Older Adult Men and Women | NCT03562468 |
| A Randomized Controlled Trial of Nicotinamide Riboside Supplementation in Early Parkinson's Disease | A Randomized Controlled Trial of Nicotinamide Riboside Supplementation in Early Parkinson's Disease: the NOPARK Study | NCT03568968 |
| The Effect of Nicotinamide Riboside on Skeletal Muscle Function in Heart Failure Subjects | Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Skeletal Muscle Function in Heart Failure Subjects | NCT03565328 |
| Trial of Nicotinamide Riboside and Co-enzyme Q10 in Chronic Kidney Disease | Cross-over Randomized Controlled Trial of Coenzyme Q10 or Nicotinamide Riboside in Chronic Kidney Disease | NCT03579693 |
| Study of Nicotinamide in Early Onset Preeclampsia | Phase II Study of Nicotinamide in Early Onset Preeclampsia | NCT03419364 |
| Nicotinamide Riboside in Hospitalized Patients | Shorter Recovery Time After Critical Illness | NCT04110028 |
| Nicotinamide Riboside as an Enhancer of Exercise Therapy in Hypertensive Older Adults (The NEET Trial) | Nicotinamide Riboside as an Enhancer of Exercise Therapy in Hypertensive Older Adults (The NEET Trial) | NCT04112043 |
| Cross-over trial to verify safety and effectiveness of nicotinamide riboside for patients with Werner syndrome | Prospective, single-center, cross-over trial to verify safety and effectiveness of nicotinamide riboside for patients with Werner syndrome - EMPOWER | JPRN-jRCTs031190141 |
| Pharmacodynamics and Tolerance of Nicotinamide Mononucleotide (NMN, 400mg/Day) in Healthy Adults | Pharmacodynamics and Tolerance Study of Nicotinamide Mononucleotide (NMN) Supplementation at 400 mg/Day | NCT04862338 |
| Safety and Pharmacokinetics of Nicotinamide Mononucleotide (NMN) in Healthy Adults. | A Single-centre Trial to Investigate the Safety and Pharmacokinetics of Orally Administered Nicotinamide Mononucleotide (NMN, 400mg) Over 29 Days of Supplementation in Healthy Adults. | NCT04910061 |
| Nicotinamide Mononucleotide in Hypertensive Patients | Pilot Study of Nicotinamide Mononucleotide Supplementation in Patients With Hypertension | NCT04903210 |
| Study to evaluate the efficacy and safety of Nicotinamide DS compared to Ciclopirox olamine at 1% cream in seborrheic dermatitis. | A prospective, randomized, multicenter, open- label, two-arm and parallel-group Study to evaluate the efficacy and safety of Nicotinamide DS compared to Ciclopirox olamine cream at 1% in patients affected by seborrheic dermatitis. - IDI01/2020 | EUCTR2020-000720-19-IT |
| Nicotinamide-based Supportive Therapy in Lymphopenia for Patients With COVID-19 | Efficiency and Safety of Nicotinamide-based Supportive Therapy in Lymphopenia for Patients With COVID-19: A Randomized Clinical Trial | NCT04910230 |
| The effect of the addition of carbogen inhalation and nicotinamide to conventional chemotherapy for hypoxia parameters in non-Hodgkin lymphoma patients | The effect of the addition of carbogen inhalation and nicotinamide to conventional chemotherapy against hypoxia, angiogenesis, apoptotic pathway, glycolytic metabolism, and inflammatory pathway parameters in diffuse large B-cell lymphoma patients | ISRCTN77237304 |
| Nicotinamide for Prevention of Pre-malignant Actinic Keratosis in Kidney Transplant Recipients | Nicotinamide for Prevention of Pre-malignant Actinic Keratosis in Kidney Transplant Recipients: A Pilot Study | NCT04843553 |
| Inflammation in COPD and the Effect of Nicotinamide Riboside | Effects of Nicotinamide Riboside on the Airway Inflammation of Older Adults With COPD: A Randomized, Double-blind, Placebo-controlled Clinical Trial (NR-COPD) | NCT04990869 |
| A Trial of Nicotinamide/Pterostilbene Supplement in ALS: The NO-ALS Extension Study | A Randomized Placebo-controlled Trial of Nicotinamide/Pterostilbene Supplement in ALS: The NO-ALS Study. Extension Protocol | NCT05095571 |
| The ENHANCE study. Can a daily supplement improve egg quality?The effects of NR (Nicotinamide riboside) supplementation on the egg quality of women of advanced age undergoing IVF: a randomised placebo-controlled double-blind proof of concept clinical trial | The ENHANCE study. Can a daily supplement improve egg quality?The effects of NR (Nicotinamide riboside) supplementation on the egg quality of women of advanced age undergoing IVF: a randomised placebo-controlled double-blind proof of concept clinical trial | ACTRN12621001699853 |
| Study to Evaluate the Effect of Nicotinamide Mononucleotide (NMN) As an Adjuvant to Standard of Care (SOC) On Fatigue Associated With COVID-19 Infection | A Randomized, Double Blind, Placebo-Controlled Study to Evaluate the Effect of Nicotinamide Mononucleotide (NMN) As an Adjuvant to Standard of Care (SOC) On Fatigue Associated With COVID-19 Infection | NCT05175768 |
| Nicotinamide Riboside Clinical Trial for GWI | A Randomized Double-blind Placebo-controlled Clinical Trial of Nicotinamide Riboside for Restoring Mitochondrial Bioenergetics in Gulf War Illness | NCT05243290 |
| A Randomized, Double Blind, Placebo-Controlled Study to Evaluate the Effectof Nicotinamide Mononucleotide (NMN) As an Adjuvant to Standard of Care (SOC) OnFatigue Associated with COVID-19 Infection | A Randomized, Double Blind, Placebo-Controlled Study to Evaluate the Effectof Nicotinamide Mononucleotide (NMN) As an Adjuvant to Standard of Care (SOC) OnFatigue Associated with COVID-19 Infection | CTRI/2022/02/040399 |
| Testing the ability of oral nicotinamide riboside to replenish heart tissue levels of oxidized nicotinamide adenine dinucleotide using heart biopsies taken at the time of surgery. | Determining Feasibility of Human Myocardial NAD+ Replenishment using Oral Nicotinamide Riboside Supplementation in Adults with Diastolic Dysfunction – The CardioNAD Study | ACTRN12622000340730 |
| The Effect of Exercise and Nicotinamide Riboside Muscle Health and Insulin Resistance in Survivors of Childhood Cancer | The Effect of Exercise and Nicotinamide Riboside on Muscle Health and Insulin Resistance in Adult Survivors of Childhood Cancer With Prediabetes: A Pilot Feasibility Study | NCT05023993 |
| The Glaucoma Nicotinamide Trial | The Glaucoma Nicotinamide Trial - A Prospective, Randomized, Placebo-controlled, Double-masked Trial | NCT05275738 |
| Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia (CLL) With History of Non-melanoma Skin Cancers (NMSC) | Randomized Phase 2 Studying the Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia (CLL) With History of Non-melanoma Skin Cancers (NMSC) | NCT04844528 |
| Nicotinamide Riboside in SARS-CoV-2 (COVID-19) Patients for Renal Protection | NIRVANA: NIcotinamide Riboside in SARS-CoV-2 pAtients for reNAl Protection | NCT04818216 |
| Measurement of NAD+ metabolites in blood after oral intake of Vitamin B3 | Mesurement of blood levels of orally-administered Nicotinamide Powder 10% Zonne and its NAD+ pathway metabolites | JPRN-jRCTs041190107 |
| Study of Nicotinamide Riboside Supplementation in Allogeneic Hematopoietic Cell Transplantation | A Pilot Study of Nicotinamide Riboside Supplementation in Allogeneic Hematopoietic Cell Transplantation | NCT04332341 |
| Improvement of the nutritional status regarding nicotinamide (vitamin B3) and the course of COVID-19 disease | Improvement of the nutritional status regarding nicotinamide (vitamin B3) and the course of COVID-19 disease - COVit | DRKS00021214 |
| Effects of Nicotinamide Riboside on the Clinical Outcome of Covid-19 in the Elderly | Effects of Nicotinamide Riboside on the Clinical Outcome of Covid-19 in the Elderly. A Randomized Double-blind, Placebo-controlled Trial of Nicotinamide Riboside NR-COVID19 | NCT04407390 |
| Effects of Nicotinamide Riboside on Bioenergetics and Oxidative Stress in Mild Cognitive Impairment/Alzheimer's Dementia | Effects of Orally Administered Nicotinamide Riboside on Bioenergetic Metabolism, Oxidative Stress and Cognition in Mild Cognitive Impairment and Mild Alzheimer's Dementia | NCT04430517 |
| Clinical trial of nicotinamide combined with estrogen and progesterone on primary ovarian insufficiency | Clinical trial of nicotinamide combined with estrogen and progesterone on primary ovarian insufficiency | ChiCTR2000035390 |
| A clinical trial on Supplemental Nicotinamide to reduce severity of symptoms of schizophrenia | Supplemental Nicotinamide In the Treatment of Schizophrenia (SNITS): A clinical trial to reduce severity of symptoms of schizophrenia - SNITS | CTRI/2021/04/032694 |
| Mechanistic Studies of Nicotinamide Riboside in Human Heart Failure | Mechanistic Studies of Nicotinamide Riboside in Human Heart Failure | NCT04528004 |
| A Phase I, double-blind, randomised, placebo-controlled, single-ascending and multiple-ascending dose trial to evaluate safety and pharmacokinetics of oral controlled-ileocolonic-release nicotinamide (CICR-NAM) compared to immediate-release nicotinamide and placebo in healthy subjects and in patients with inflammatory bowel diseases | A Phase I, double-blind, randomised, placebo-controlled, single-ascending and multiple-ascending dose trial to evaluate safety and pharmacokinetics of oral controlled-ileocolonic-release nicotinamide (CICR-NAM) compared to immediate-release nicotinamide and placebo in healthy subjects and in patients with inflammatory bowel diseases - CICR-NAM Phase I | DRKS00023384 |
| Impacts of Nicotinamide Riboside on Functional Capacity and Muscle Physiology in Older Veterans | Impacts of Nicotinamide Riboside on Functional Capacity and Muscle Physiology in Older Veterans | NCT04691986 |
| Effect of NMN on Muscle Recovery and Physical Capacity in Healthy Volunteers With Moderate Physical Activity | Randomized, Double-blind, Placebo-controlled Clinical Trial of Nicotinamide Mononucleotide on Muscle Recovery and Physical Capacity in Healthy Volunteers With Moderate Physical Activity | NCT04664361 |
| Nicotinamide to Prevent Delirium | Nicotinamide, an Inhibitor of PARP-1, for Preventing Delirium in Older Adults | NCT04725253 |
| Improvement of the Nutritional Status Regarding Nicotinamide (Vitamin B3) and the Disease Course of COVID-19 | Improvement of the Nutritional Status Regarding Nicotinamide (Vitamin B3) and the Disease Course of COVID-19 | NCT04751604 |
| Prevention of Skin Cancer with nicotinamide in Transplant recipients | Nicotinamide as chemoprevention of Skin Cancer in Transplant recipietns | RBR-8ht6j7q |
| The NO-ALS Study: a Trial of Nicotinamide/pterostilbene Supplement in ALS. | A Randomized Placebo-controlled Trial of Nicotinamide/pterostilbene Supplement in ALS: the NO-ALS Study | NCT04562831 |
| Vitamin B-12 in Infantile Tremor Syndrome Study (BITS study) | A Randomized Controlled Trial comparing Vitamin B12 monotherapy versus combination multinutrient therapy with Vitamin B12 for efficacy in treatment of Infantile Tremor Syndrome - BITS | CTRI/2018/05/013841 |
| Nicotinamide and Glaucoma | Nicotinamide and Glaucoma | NCT05916066 |
| Clinical study on efficacy and safety of 30% supramolecular salicylic acid combined with 10% niacinamide in the treatment of chloasma | Clinical study on efficacy and safety of 30% supramolecular salicylic acid combined with 10% niacinamide in the treatment of chloasma - Clinical study of supramolecular salicylic acid on melasma | ChiCTR2200065346 |
| Anti-acne test of Asaya Serum | A consumer study to check anti-acne activity of Asaya 2% Salicylic Acid and 5% Niacinamide Serum - NIL | CTRI/2024/10/074852 |
| NiaMIT Continuation With Early-stage Mitochondrial Myopathy Patients | NiaMIT (NiaMIT_0001) Continuation for Early-stage Mitochondrial Myopathy Patients to Investigate the Effect of Niacin Supplementation on Systemic Nicotinamide Adenine Dinucleotide (NAD+) Metabolism, Physiology and Muscle Performance | NCT04538521 |
| Prevalence of Vitamin B-12 and Vitamin D deficiency in healthcare professionals | Prevalence of Vitamin B-12 and Vitamin D deficiency in healthcare professionals | TCTR20190412001 |
| The Effectiveness of Fixed Dose Combination of Alpha Lipoic Acid and Vitamin B Preparations for Treatment of Diabetic Polyneuropathy in Type 2 diabetes mellitus patients: A randomized placebo-controlled trial | The Effectiveness of Fixed Dose Combination of Alpha Lipoic Acid and Vitamin B Preparations for Treatment of Diabetic Polyneuropathy in Type 2 diabetes mellitus patients: A randomized placebo-controlled trial | TCTR20250608002 |
| comparing the efficacy and safety of a new Vitamin B 12 Nasal Spray vs Oral Supplement in treating Vitamin B 12 Deficiency | A prospective, open-label, randomized, comparative clinical trial to assess theefficacy and safety of a novel Methylcobalamin Nasal Spray (NASO B12) or oral B12 supplementation in the treatment of subjects with vitamin B12 deficiencyas well as to evaluate the duration of efficacy - Nill | CTRI/2024/10/075367 |
| Niacin Supplementation in Healthy Controls and Mitochondrial Myopathy Patients | The Effect of Niacin Supplementation on Systemic Nicotinamide Adenine Dinucleotide (NAD+) Metabolism, Physiology and Muscle Performance in Healthy Controls and Mitochondrial Myopathy Patients | NCT03973203 |
| impact of abnormal genes and vitamin B supplementation on hyperhomocysteinemia among ischemic stroke patients | Impact of MTHFR, MS and CBS genes polymorphisms and vitamin B6, B9 & B12 supplementations on hyperhomocysteinemia among Ischemic stroke patients. | CTRI/2020/03/024293 |
| Dietary Riboflavin (Vitamin B-2) and Cornea Cross-Linking | Dietary Riboflavin (Vitamin B-2) and Cornea Cross-Linking | NCT03095235 |
| Vitamin B Multivitamin Supplement on Neural Connectivity and Oxidative Metabolism | Effect of High-Dose-Vitamin-B Multivitamin Supplement on Neural Connectivity and Oxidative Metabolism in Healthy Adults: A Randomised, Double-Blind, Placebo-Controlled, Phase I Clinical Trial | ACTRN12622001150730 |
| Effect of white egg and Niacin on hemodialysis patients | Evaluation the efficacy of Dietary Pasturized egg white with and without Niacinamide for phosphorus control in End Stage Renal Disease patients on Haemodialysis | IRCT2016102226390N5 |
| Vitamin B Therapy for Hyperlactatemia | A Pilot Study of Oral B Vitamin Therapy for Asymptomatic or Mildly Symptomatic Hyperlactatemia in Patients on NRTIs | NCT00031057 |
