IMPPAT Phytochemical information: 
L-Theanine

L-Theanine
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
Cystine & Theanine (CT) study: for less invasiveness of laparoscopic colorectomyCystine & Theanine (CT) study: for less invasiveness of laparoscopic colorectomy - CT studyJPRN-UMIN000015570
Effects of L-Theanine in Boys With ADHDA Double Blind, Randomized Placebo Controlled Clinical Trial Examining the Effects of L-Theanine (Suntheanine®) in Male Child Subjects With Attention Deficit Hyperactivity DisorderNCT00291070
Effects of a Theanine for Stress Relief Formulation in Individuals Who Report Occasional Moderate High Levels of Stress.A Double-blind, Randomized, Placebo-controlled Study to Evaluate the Effects of a Theanine for Stress Relief Formulation on Stress, Burnout Component, Mood, and Sleep in Individuals Who Report Occasional Moderate or High Levels of StressNCT05854017
The effect of supplementation with a blackcurrant drink containing L-theanine and pine bark extract in supporting cognitive performance in healthy older adultsInvestigating the effect of acute and long-term supplementation with a blackcurrant beverage containing L-theanine and pine bark extract in supporting cognitive performance in healthy older adults.ACTRN12621001590853
A study for evaluating effects of ingested amino acids, cystine and theanine, on postoperative amount of activity.A study for evaluating effects of ingested amino acids, cystine and theanine, on postoperative amount of activity. - A study for evaluating effects of ingested amino acids, cystine and theanine, on postoperative amount of activity.JPRN-UMIN000020779
L-Theanine in the Adjunctive Treatment of Generalised Anxiety Disorder: A Double-Blind Randomised Placebo-Controlled TrialL-Theanine in the Adjunctive Treatment of Generalised Anxiety Disorder: A Double-Blind Randomised Placebo-Controlled TrialACTRN12616000759493
Investigation of the effect of L-theanine on improving sleep habitsInvestigation of the effect of L-theanine on improving sleep habits - Investigation of the effect of L-theanine on improving sleep habitsJPRN-UMIN000052597
Perioperative oral administration of Cystine and Theanine enhances recovery after thoracoscopic esophagectomyPerioperative oral administration of Cystine and Theanine enhances recovery after thoracoscopic esophagectomy - Perioperative oral administration of Cystine and Theanine enhances recovery after thoracoscopic esophagectomyJPRN-UMIN000024849
Theanine and Caffeine on Neurophysiology of AttentionNeurophysiological Correlates of L-theanine, Caffeine and Their Combination on Improving Selective Attention in a Visual Reaction Time Task: A Functional Magnetic Resonance Imaging (fMRI) StudyNCT02770105
Ameliorating effect of food product including Theanine and Casein peptide on sleep in postmenopausal women with complain of deteriorated sleep health : A randomized, double blind, placebo-controlled trialAmeliorating effect of food product including Theanine and Casein peptide on sleep in postmenopausal women with complain of deteriorated sleep health : A randomized, double blind, placebo-controlled trial - Effect of Theanine and Casein peptide on sleep: A randomized, double blind, placebo-controlled trialJPRN-UMIN000018725
Comparing the effectiveness of the combination of caffeine, L-theanine and piperin compared to placebo and pure caffeine in increasing attentionInvestigating the effectiveness of capsules containing the combination of caffeine, L-theanine and piperin compared to pure caffeine and placebo in improving attention in healthy peopleIRCT20160306026938N19
The effect of green tea amino acid L-Theanine formulation on markers of stress and quality of sleep (THESLeep Project)The effect of green tea amino acid L-Theanine formulation on markers of stress and quality of sleep in adults with mild to moderate sleep disturbances (THESLeep Project).ACTRN12623000776606
Exploratory randomized controlled trial of cystine-theanine for cancer cachexiaAn exploratory randomized controlled trial of cystine-theanine for cancer cachexia - An exploratory randomized controlled trial of cystine-theanine for cancer cachexiaJPRN-jRCTs021240010
The Effect of the Amino Acid L-Theanine on Alertness and VigilanceThe Effect of the Amino Acid L-Theanine on Alertness and VigilanceNCT01851122
Effect of L-theanine on depressive symptomsEffect of L-theanine on depressive symptoms - Effect of L-theanine on depressive symptomsJPRN-UMIN000014653
Effectiveness of combined use of theanine and arginine for psychological stressEffectiveness of combined use of theanine and arginine for psychological stress - Effectiveness of combined use of theanine and arginine for psychological stressJPRN-UMIN000040967
Effects of L-theanine and Caffeine on Attention and Attention-related Brain Activity of Children With Attention Deficit Hyperactivity DisorderEffects of L-theanine and Caffeine on Attention and Attention-related Brain Activity of Male Children and Adolescents With Attention Deficit Hyperactivity Disorder: a proof-of- Concept fMRI Study.NCT03533556
Acute effects of a single dose of L-theanine and caffeine combination compared to a placebo on reaction time, and brain activity underlying selective attention in acutely sleep-deprived healthy adults.Acute effects of a single dose of L-theanine and caffeine combination on selective attention in acutely sleep-deprived healthy adultsSLCTR/2023/006
Effects of Caffeine, L-Theanine, and Diaphragmatic Breathing on Esports Players' PerformanceCan L-Theanine Supplementation or Diaphragmatic Breathing Exercises in Addition to Caffeine Supplementation Be Used as Ergogenic Aids to Influence Game Performance in Esports Players?NCT06621797
A study for evaluating efficacy of cystine and theanine against peripheral neuropathy of oxaliplatin as a supportive treatmentA study for evaluating efficacy of cystine and theanine against peripheral neuropathy of oxaliplatin as a supportive treatment - A study for evaluating efficacy of cystine and theanine against peripheral neuropathy of oxaliplatin as a supportive treatmentJPRN-UMIN000020456
L-Theanine for the treatment of obsessive-compulsive disorderL-Theanine combination therapy with Fluvoxamine in moderate to severe obsessive-compulsive disorder: A placebo-controlled, double-blind, randomized trialIRCT20090117001556N134
The Effects of Caffeine and L-theanine Both Alone and in Combination on Cerebral Blood Flow, Cognition and MoodA Randomised, Double Blind, Placebo-controlled Study to Evaluate the Effects of Caffeine and L-theanine Both Alone and in Combination on Cerebral Blood Flow, Cognition and Mood.NCT00981955
L-Theanine as an adjuvant therapy in the treatment of major depressive disorderL-Theanine as an adjuvant therapy in the treatment of major depressive disorder: a double-blind, randomized, placebo-controlled clinical trialIRCT20090117001556N131
L-Theanine as an adjuvant therapy for chronic schizophreniaL-Theanine as an adjuvant therapy added to Risperidone for the treatment of patients with chronic schizophrenia: A randomized double blind and placebo controlled clinical trialIRCT20090117001556N133
effects of use of pre operattive l theanine and gabaCOMPARISON OF THE EFFECTS OF TWO AMINO ACIDS: GAMMA-AMINOBUTYRIC ACID AND L-THEANINE ON SEDATION, ANXIETY AND COGNITION IN PRE-OPERATIVE SURGICAL PATIENTS-A RANDOMISED CONTROLLED TRIAL - CTGLSACCTRI/2021/08/035694
Efficacy of Oral Administration of Cystine and Theanine in Colorectal Cancer Patients Undergoing Capecitabine based Adjuvant Chemotherapy after Surgery: Randomized, Double-blind, Placebo controlled, Phase-II StudyEfficacy of Oral Administration of Cystine and Theanine in Colorectal Cancer Patients Undergoing Capecitabine based Adjuvant Chemotherapy after Surgery: Randomized, Double-blind, Placebo controlled, Phase-II Study - Efficacy of Cystine and Theanine in Colorectal Cancer Patients Undergoing Capecitabine after Surgery: Placebo controlled, Phase-II StudyJPRN-UMIN000024784
Effect of a formulation containing blackcurrant powder, L-theanine and pine bark extract on immune responses to influenza vaccine in older healthy adultsEffect of a formulation containing blackcurrant powder, L-theanine and pine bark extract on immune responses to influenza vaccine in older healthy adultsA multi-centred, randomised, double blind, placebo controlled, parallel studyACTRN12621001561875
L-Theanine in the Management of SchizophreniaThe Value of Augmenting L-Theanine in the Management of Schizophrenia: A Randomized, Double-Blind, Placebo-Controlled Clinical TrialNCT00372151
An evaluation of theanine consumption on sleeping and stress in middle-aged and older malesAn evaluation of theanine consumption on sleeping and stress in middle-aged and older males - An evaluation of theanine consumption on sleeping and stress in middle-aged and older malesJPRN-UMIN000046373
Evaluate the Effects of a Theanine Formulation on Stress, Burnout, Mood, and Sleep in Individuals Who Report Occasional Moderate or High Levels of StressA Double-blind, Randomized, Placebo-controlled Study to Evaluate the Effects of a Theanine Formulation on Stress, Burnout, Mood, and Sleep in Individuals Who Report Occasional Moderate or High Levels of StressNCT05450952
Anti-stress Effect of Theanine on Students During Long-term Pharmacy PracticesMeasurement of Stress Symptom in Students During Long-term Pharmacy Practices and Evaluation of Anti-stress Effect of Theanine Consumption on StudentsNCT01361204
The anxiolytic and cognitive effects of L-theanineThe anxiolytic and cognitive effects of L-theanine - The anxiolytic and cognitive effects of L-theanineNL-OMON47787
A Clinical Trial to Assess the Efficacy of AlphaWave® L-Theanine on Cognitive Function in Healthy Adults With Moderate StressA Randomized, Triple-blind, Placebo Controlled, Cross-over Clinical Trial to Assess the Efficacy of AlphaWave® L-Theanine on Cognitive Function in Healthy Adults With Moderate StressNCT07004023
Effects of L-theanine on Motor Cortex Excitability in Healthy Subjects: A Paired-Pulse TMS StudyEffects of Single-dose L-theanine on Motor Cortex Excitability in Healthy Subjects: A Double-blinded, Randomized Order, Cross-over Paired-Pulse Transcranial Magnetic Stimulation StudyNCT04749745
Assessment of anti-stress, behavioural, and neurophysiological effects of L-theanine: A randomised, double-blind, placebo-controlled, crossover trialAssessment of anti-stress, behavioural, and neurophysiological effects of L-theanine: A randomised, double-blind, placebo-controlled, crossover trial in healthy adultsACTRN12614000826640
The effectiveness of L-theanine-caffeine combination given as a supplement compared to methylphenidate and placebo on improvement of selective attention in adolescents (age 10-19 years old) with attention-deficit hyperactive disorder: a double-blind, 3-way crossover trialAcute effects of L-theanine and caffeine combination on selective attention in adolescents with attention deficit hyperactivity disorderSLCTR/2023/004
Pregnenolone and L-theanine Augmentation in the Treatment for Schizophrenia and Schizoaffective DisordersAddition of Both Pregnenolone and L-theanine to Ongoing Antipsychotic Treatment for Schizophrenia and Schizoaffective Disorders: an 8-week, Randomized, Double-blind, Placebo-controlled Multicenter StudyNCT01831986
The oral administration of amino acids cystine and theanine for patients with advanced EGFR mutation-positive non-small-cell lung cancerThe oral administration of amino acids cystine and theanine for patients with advanced EGFR mutation-positive non-small-cell lung cancer - Trial of amino acids cystine and theanineJPRN-UMIN000020781
The Safety and Efficacy of AlphaWave® L-Theanine on Adults Who Experience Moderate Stress on a Regular BasisA Randomized, Double-blind, Placebo Controlled, Parallel Clinical Trial to Investigate the Efficacy of AlphaWave® L-Theanine on Adults Who Experience Moderate Stress on a Regular BasisNCT05808595
Effects of L-theanine and GABA on sleepBefore-after study on the effects of L-theanine and GABA on sleep in adults with sleep problems. - Before-after study on the effects of L-theanine and GABA on sleepJPRN-UMIN000050613
Study on work efficiency and fatigue improvement effect of green tea containing high theanineStudy on work efficiency and fatigue improvement effect of green tea containing high theanine - Effect of green tea containing high theanineJPRN-UMIN000034209
Effect of L-theanine on depressive symptoms and cognitive functionsEffect of L-theanine on depressive symptoms and cognitive functions - Effect of L-theanine on depressive symptoms and cognitive functionsJPRN-UMIN000028603