| To Assess Efficacy and Safety of Enzomac in patients with Osteoarthritis | A Prospective, Single-center, Open label, Randomized, Parallel-group, Comparative Clinical Study to Evaluate the Efficacy and Safety of FDC of Trypsin + Bromelain + Rutoside trihydrate versus FDC of Glucosamine sulphate + Chondroitin sulfate and Collagen peptide in the Treatment of Patients with Osteoarthritis | CTRI/2020/03/024039 |
| A comparison of the effects of two sugar-free chewing gums to repair early tooth decay. | A comparison of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) prepared using microbial or porcine trypsin/chymotrypsin to remineralize subsurface enamel lesions in healthy adults in situ. | ACTRN12621001416886 |
| A clinical study of Trypsin, Bromelain and Rutoside combination in wound management. | An open label, prospective, multicentric, randomized, controlled, comparative clinical trial to evaluate the safety and efficacy of fixed dose combination of Trypsin 48mg, Bromelain 90mg and Rutoside 100mg tablets in comparison to Trypsin: Chymotrypsin tablets with 1,00,000 armour units of enzymatic activity in wound management. | CTRI/2021/07/035082 |
| Study to evaluate the safety and efficacy of Fixed Dose Combination of Trypsin-Chymotrypsin, Bromelain and Rutoside Trihydrate Tablets. | ââ?¬Å?An Open Label, Prospective, Non-comparative, Multicentre, Phase IV Clinical Study to Evaluate the Safety, Tolerability and Efficacy of FDC of Trypsin - Chymotrypsin 50000 AU plus Bromelain 90 mg plus Rutoside Trihydrate 100 mg Tablets in Subjects for the treatment of conditions associated with Inflammation and edema of traumatic origin.ââ?¬? | CTRI/2021/10/037277 |
| To Assess Efficacy and Safety of Enzomac in patients with Osteoarthritis | A Prospective Single center Open label Randomized Parallel group Comparative Clinical Study to Evaluate the Efficacy and Safety of FDC of Trypsin Bromelain Rutoside trihydrate versus FDC of Glucosamine sulphate Chondroitin sulfate and Collagen peptide in the Treatment of Patients with Osteoarthritis | CTRI/2020/10/028616 |
| The Effect of Three Different Medications on Anesthetic Success and Postoperative Pain | The Effect of Premedication With Trypsin, Bromelain and Rutoside Combination on the Success of IAN Block and Post Endodontic Pain in Patients With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial | NCT06298383 |
| Study of the mechanism of action of a medicinal product based on Bromelain, Trypsin and Rutoside, compared to the same medicinal product without active ingredient called Placebo in subjects suffering from osteoarthritis. | A Randomized, Double-blind, Placebo-controlled, Crossover Study to Investigate the Mechanism of Action of an Oral Enzyme Treatment with Bromelain, Trypsin and Rutoside versus Placebo in Subjects with OsTeoarthritis (WOBE-SMART) - WOBE-SMART study | EUCTR2020-003154-80-BE |
| Comparison of the effectiveness of proteolytic enzymes and diclofenac in patients with impacted third molars in the mandible. | Comparison of efficacy of combinations of proteolytic enzymes (trypsin, bromelain, and rutoside) and diclofenac versus serratiopeptidase and diclofenac versus diclofenac alone in patients with similar Pederson’s difficulty index impacted mandibular third molars in a randomised control double blind trial - NIL | CTRI/2023/08/056907 |
| Effectiveness of proteolytic enzymes in controlling the post operative sequelae of surgical third molar disimpactions | Prospective, Observer Blinded, Randomized Clinical Study to Evaluate the Effectiveness of Trypsin, Bromelain, Rutoside Fixed Dose Combination and Trypsin, Chymotrypsin Fixed Dose Combination on Post-Operative Pain, Swelling and Trismus following the Surgical Removal of an Impacted Mandibular Third Molar. | CTRI/2017/10/010076 |
| A Study to evaluate the Safety and Efficacy of FDC of Trypsin 48 mg plus Bromelain 90 mg plus Rutoside Trihydrate 100 mg plus Diclofenac Sodium 50 mg enteric coated tablet versus Diclofenac Sodium 50 mg enteric coated tablet in patients with surgical wounds after minor surgery. | A Multicentric, Open label, Randomized, Comparative, Clinical Study evaluating Safety and Efficacy of Fixed Dose Combination of Trypsin 48 mg plus Bromelain 90 mg plus Rutoside Trihydrate 100 mg plus Diclofenac Sodium 50 mg enteric coated tablet versus Diclofenac Sodium 50 mg enteric coated tablet in patients for healing potential in surgical wounds after minor surgery. | CTRI/2017/11/010384 |
| Phlogam and Disperzyme use for reducing pain and swelling after small surgery | A multicentre, randomized, assessor blind, active controlled, comparative, phase IV study to assess the safety and efficacy of two fixed dose combinations (FDC) formulations of trypsin BP 48/96mg plus bromelain 90/180 plus Rutoside trihydrate BP 100/200 mg viz Phlogam and Disperzyme in post-operative inflammation in subjects undergoing minor surgery and dental procedures | CTRI/2017/12/010804 |
| A study to evaluate the Safety and Effectiveness of Fixed Dose Combination of Trypsin 48 mg plus Bromelain 90 mg plus Rutoside Trihydrate 100 mg enteric coated tablet versus Serratiopeptidase 10 mg enteric coated tablet in patients with surgical wounds after minor surgery | A Multicentric, Open label, Randomized, Comparative, Clinical Study evaluating Safety and Efficacy of Fixed Dose Combination of Trypsin 48 mg plus Bromelain 90 mg plus Rutoside Trihydrate 100 mg enteric coated tablet versus Serratiopeptidase 10 mg enteric coated tablet in patients for healing potential in surgical wounds after minor surgery | CTRI/2018/04/013151 |
| A study of Trypsin, Bromelain, Rutoside and Diclofenac combination in comparison with Diclofenac to observe rapid healing of the wound and reducing pain intensity in surgery patients. | An open label, multicentric, randomized, comparative clinical trial to evaluate safety and efficacy of fixed-dose combination of Trypsin 48 mg, Bromelain 90 mg, Rutoside 100 mg and Diclofenac 50 mg tablet in comparison to Diclofenac 50 mg tablet in wound management. | CTRI/2021/03/032053 |
| Effectiveness of a Gel with Glucosamine and Other Ingredients in Reducing Pain from Jaw Muscle and Disc Problems A Clinical Study | Evaluation of the Effectiveness of Glucosamine and Bromelain-Trypsin-Rutoside Combination Gel in the Management of Myogenous and Disc Disorders of Temporomandibular Joint- A Randomised Clinical Trial - NIL | CTRI/2025/04/085392 |
| Study to compare efficacy and safety of trypsion plus bromelain plus rutoside tablet along with cefuroxime axetil tablet versus cefuroxime axetil tablet given alone in patients with surgical wound after minor surgery | A Prospective, Single-center, Open label, Randomized, Parallel-group, Active-controlled Clinical Study to Evaluate the Efficacy and Safety of FDC of Trypsin plus Bromelain plus Rutoside trihydrate given along with Cefuroxime axetil versus Cefuroxime axetil for Healing in Patients with Surgical Wound after Minor Surgery | CTRI/2020/08/027070 |
| A clinical trial to study the effects of a combination of trypsin-chymotrypsin enzymes and diclofenac in comparison to diclofenac alone in patients with soft tissue injuries. | A randomized, double blind, comparative, parallel-group clinical trial to evaluate the efficacy and safety of a combination of trypsin-chymotrypsin enzymes and diclofenac (TCD) in comparison to diclofenac alone in the management of inflammation due to soft tissue injuries | CTRI/2009/091/000813 |
| Serum Basal Tryptase Levels in Healthy Children | Evaluation of Basal Tryptasemia According to Age in a Pediatric Control Population | NCT05323188 |
| Assessment of Serum and Tissue Tryptase Levels in Acne Vulgaris Patients | Assessment of Serum and Tissue Tryptase Levels in Acne Vulgaris Patients | NCT06158061 |
| A clinical trial to compare the effects of two methods of obtaining hair stem cells for treating vitiligo | A comparative study to assess the efficacy and composition of various cell populations of extracted hair follicle outer root sheath cell suspensions (EHF ORS CS) prepared using a single enzyme (trypsin) and multiple enzymes (trypsin and collagenase) for transplantation in vitiligo | CTRI/2016/08/007133 |
| To Evaluate Efficacy and Safety of Fixed dose combination of Trypsin - Chymotrypsin Enzyme and Diclofenac OralTablet in comparison with Diclofenac oral Tablet in soft tissue injuries | A Multicentric, Randomized, Prospective, Open Label, Comparative,Parallel Group Clinical Trial to Evaluate the Efficacy and Safety of Fixeddose combination of Trypsin - Chymotrypsin Enzyme and Diclofenac OralTablet in comparison with Diclofenac oral Tablet in the management ofacute inflammation due to soft tissue injuries | CTRI/2017/10/010223 |
| Gluten and Amylase Trypsin Inhibitors (ATI) Free Diet | Gluten and Amylase Trypsin Inhibitors (ATI) as Nutritional Contributors to Type 1 Diabetes Susceptibility | NCT03443180 |
| Evaluation of safety and Efficacy of Chymoral Forte in wound healing potential after orthopaedic surgery. | "Comparative Evaluation Of Trypsin:Chymotrypsin (6:1) Versus Serratiopeptidase For Their Healing Potential In Surgical Wounds After Orthopedic Surgery: Open, Prospective, Randomized, Comparative Study""" | CTRI/2011/07/001920 |
| Comparing Trypsin-Chymotrypsin and Naproxen Sodium for Post-endodontic Treatment Pain | Comparing Trypsin-Chymotrypsin and Naproxen Sodium for Post-endodontic Treatment Pain: a Randomized Controlled Trial | NCT06562816 |
| To check effectiveness Of Trypsin : Chymotrypsin Combination In reduction Of Pain And swelling Post Elective Inguinal Hernia Surgeries. | Evaluation Of Efficacy And Therapeutic Value Of Trypsin : Chymotrypsin Fixed Dose Combination In Management Of post opeative Pain And Oedema Post Elective Open Inguinal Hernia Surgeries. - A Randomised Control Trial. | CTRI/2020/06/026159 |
| Comparison of combination of Diclofenac, Paracetamol, Trypsin, and Chymotrypsin versus combination of Diclofenac and Paracetamol in patient with soft tissue enjury. | A phase IV, randomized, multicentre, prospective, open-label, comparative, post-marketing study to evaluate safety & efficacy of combination of Diclofenac, Paracetamol, Trypsin and Chymotrypsin versus combination of Diclofenac and Paracetamol in patients with soft tissue injury. | CTRI/2021/01/030508 |
| A study to evaluate safety and efficacy of tablet containing fixed dose of Diclofenac Potassium 50mg and Paracetamol 325 mg andTrypsin Chymotrypsin 50000 AU in management of acute muscle pain | A Prospective, Multicentric, Non-comparative Phase IV Clinical Trial Evaluating Safety and Efficacy of Fixed Dose Combination (FDC) of DICLOFENAC POTASSIUM BP + PARACETAMOL IP +TRYPSIN AND CHYMOTRYPSIN (50MG-+325MG+50,000 ARMOUR) FILM COATED TABLETS in the management of acute musculoskeletal pain | CTRI/2021/03/032436 |
| In Vivo Effects of Amylase Trypsin Inhibitors | In Vivo Effects of Amylase Trypsin Inhibitors From Wheat in the Human Gut: Proof of Cause of Non-coeliac Wheat Sensitivity in Irritable Bowel Syndrome? | NCT05157867 |
| A Clinical Study to evaluate the safety and efficacy of Fixed Dose Combination of Trypsin-Chymotrypsin, Aceclofenac and Paracetamol Tablets. | ââ?¬Å?An Open Label, Prospective, Non-comparative, Multicentric, Phase IV Clinical Study to Evaluate the Safety, Tolerability and Efficacy of FDC of Trypsin ââ?¬â?? Chymotrypsin 150000 AU plus Aceclofenac 100 mg plus Paracetamol 325 mg Tablets in Patients for the treatment of acute inflammation and traumatic tissue pain.ââ?¬? | CTRI/2022/04/041691 |
| A Clinical Study to evaluate the safety and efficacy of Fixed Dose Combination of Trypsin-Chymotrypsin, Aceclofenac and Paracetamol Tablets. | ââ?¬Å?An Open Label, Prospective, Non-comparative, Multicentric, Phase IV Clinical Study to Evaluate the Safety, Tolerability and Efficacy of FDC of Trypsin ââ?¬â?? Chymotrypsin 50000 AU plus Aceclofenac 100 mg plus Paracetamol 325 mg Tablets in Patients for the treatment of acute inflammation and traumatic tissue pain.ââ?¬? | CTRI/2022/06/043590 |
| A Study to find the effect of a new irrigating solution on Pain after Root Canal Treatment. | Effect of Trypsin irrigation on post-operative pain following Single-Visit Endodontic Treatment in Mandibular Molar with Symptomatic Irreversible Pulpitis: ARandomized Controlled Clinical Study - NIL | CTRI/2024/05/067891 |
| A study to evaluate the safety tolerability and efficacy of tablets containing Trypsin Chymotrypsin Aceclofenac and Paracetamol for management of tissue pain | An Open Label Prospective Non comparative Multicentre Phase IV Clinical Study to Evaluate the Safety Tolerability and Efficacy of FDC of Trypsin Chymotrypsin 50000 AU plus Aceclofenac 100 mg plus Paracetamol 325 mg Tablets in Subjects for the treatment of acute inflammation and traumatic tissue pain - NA | CTRI/2020/11/028979 |
| To compare the effects of cisatracurium and atracurium on levels of tryptase, Ig E and absolute eosinophil count in adult patients undergoing general anesthesia for elective surgery. | Comparison of effects of cisatracurium and atracurium upon Tryptase, IgE levels and Absolute eosinophil counts in adult patients undergoing general anesthesia for elective surgery. | CTRI/2021/09/036550 |
| A study to evaluate the Safety and Effectiveness of Fixed Dose Combination of Trypsin 96 mg plus Bromelain 180 mg plus Rutoside Trihydrate 200 mg versus Trypsin - chymotrypsin (1,00,000 AU) in patients with surgical wounds after minor surgery | A Multicentric, Open label, Randomized, Comparative, Clinical Study evaluating Safety and Efficacy of Fixed Dose Combination of Trypsin 96 mg plus Bromelain 180 mg plus Rutoside Trihydrate 200 mg enteric coated tablet versus Chymoral Forte (Trypsin - chymotrypsin (1,00,000 AU)) enteric coated Tablet in patients for healing potential in surgical wounds after minor surgery | CTRI/2017/10/010004 |
| A Prospective Clinical Trial Comparing Serum Mast Cell Tryptase (SMCT) Levels to Arthrofibrosis Rates Among Primary Total Knee Arthroplasty (TKA) Patients | A Prospective Clinical Trial Comparing Serum Mast Cell Tryptase (SMCT) Levels to Arthrofibrosis Rates Among Primary Total Knee Arthroplasty (TKA) Patients | NCT03598829 |
| Simultaneous Study of the Serum Tryptase Level of the Mother and the Child During Childbirth (TryPla) | Simultaneous Study of the Serum Tryptase Level of the Mother and the Child During Childbirth | NCT04441463 |
