IMPPAT Phytochemical information: 
Capsaicin

Capsaicin
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
The role of topical capsaicin gel in pain management during microfocused ultrasound treatment for neck laxityThe role of topical capsaicin gel in pain management during microfocused ultrasound treatment for neck laxityTCTR20220225006
The Influence of Capsaicin Gel During Exercise Within the HeatThe Influence of Topical Capsaicin on Thermoregulatory and Perceptual Outcomes During Exercise Within the HeatNCT05298202
Effect of capsaicin oropharyngeal stimulation on swallowing function in patients with dysphagia after posterior fossa surgeryEffect of capsaicin oropharyngeal stimulation on swallowing function in patients with dysphagia after posterior fossa surgeryChiCTR2200062274
Capsaicin for Cerebral Perfusion AugmentationEffect of Capsaicin on the Augmentation of Cerebral Perfusion. A Phase II Study.NCT05543837
Analgesic Efficacy of Capsaicin 8% Patch (QUTENZA®) in CoccygodygniaNeuropathic Determining Factors and Analgesic Efficacy of Capsaicin 8% (QUTENZA®) Patches in Refractory CoccygodygniaNCT05983263
Pre-emptive Analgesia With Qutenza in Lower Limb AmputationThe Role of Pre-emptive Analgesia With Qutenza (Topical Capsaicin 8%) in Preventing Neuropathic Pain Following Lower Limb Amputation: a Pilot Randomised Controlled StudyNCT01748435
CAPSAPEDAnalgesic effectiveness of capsaicin 8% cutaneous patch for the treatment of chronic postsurgical or post-traumatic neuropathic pain: a randomized placebo controlled study in children aged 12 to 17-y - 29BRC21.0184CTIS2022-500265-27-00
Capsaicin 179 mg Patch Versus Oral Duloxetine in Patients With Chemotherapy-induced Peripheral NeuropathyCapsaicin 179 mg Patch Versus Oral Duloxetine in Patients With Chemotherapy-induced Peripheral Neuropathy : a Phase 3 Randomized Multicentric Open-label Study.NCT05840562
Bio-availability of nasal capsaicin.Assessment of systemic pharmacokinetics of capsaicin following intranasal administration of a recognised therapeutic dose in healthy adultsACTRN12623000410651
Efficacy and Safety of the Topical Chili Extract-Loaded Lipid Nanoparticle Gel Product Containing 0.075% Capsaicin for the Treatment of Neuropathic Low Back Pain: A Randomized Controlled TrialEfficacy and Safety of the Topical Chili Extract-Loaded Lipid Nanoparticle Gel Product Containing 0.075% Capsaicin for the Treatment of Neuropathic Low Back Pain: A Randomized Controlled TrialTCTR20230608001
Study Evaluating the Analgesic Efficacy of Capsaicin 8% Patches in Chronic Coccygodynia.Phase 3 Confirmatory, Randomised 1:1 Double-blind, Placebo-controlled Study Evaluating the Analgesic Efficacy of Capsaicin 8% Patches in Chronic Coccygodynia.NCT06023706
Effect of a 35% hydrogen peroxide gel containing a composite in reducing of tooth sensitivity after in-office dental bleachingEffect of the use of a 35% hydrogen peroxide gel containing capsaicin and hydroxyapatite nanoparticles to reduce post-bleaching tooth sensitivityRBR-1083qqwy
The effect of ondansetron in reducing capsaicin inflammationEvaluation of ondansetron efficacy in reducing capsaicin-induced inflammation: a randomized crossover clinical trial.IRCT20181208041882N11
The acute effects of capsaicin on metabolism and thermogenesis in healthy adult females – a clinical trialThe acute effects of capsaicin supplements on changing energy expenditure substrate utilisation from glucose to lipid and activating brown adipose tissue in the presence of the changing hormones throughout the estrous cycle that alter temperature in healthy adult femalesACTRN12624000014550
The Effect of Capsaicin on Burning MothThe Effect of Capsaicin Oral Solution in The Treatment of Burning Mouth in Patients Attending School of Dentistry and Affiliated Hospitals of Tehran Islamic Azad University of Medical SciencesIRCT20220117053748N1
A comparative evaluation of effect of the combination of local anesthetics and capsaicin for neuropathic painA comparative evaluation of effect of the combination of local anesthetics and capsaicin for neuropathic pain - Effect of the combination of local anesthetics and capsaicinJPRN-UMIN000033571
The Effect of CPC on Aborting Tilt Induced Syncope in Patients With a History of Vasovagal Syncope or Near SyncopeThe Effect of Capsaicin-Phenylephrine-Caffeine Formulation on Aborting Tilt Induced Syncope in Patients With a History of Vasovagal Syncope or Near SyncopeNCT04972123
The Prevalence of Local Immunoglobulin E (IgE) Elevation and Its Effect on Intranasal Capsaicin Therapy in the Non-allergic Rhinitis PopulationThe Prevalence of Local IgE Elevation and Its Effect on Intranasal Capsaicin Therapy in the Non-allergic Rhinitis PopulationNCT05093478
A pilot study, The efficacy of topical 0.025% capsaicin gel in the treatment of lichen amyloidosis at Institute of dermatology, ThailandA pilot study, The efficacy of topical 0.025% capsaicin gel in the treatment of lichen amyloidosis at Institute of dermatology, ThailandTCTR20191213001
The Efficacy and Safety Profile of Capsaicin 8% Patch Versus 5% Lidocaine Patch in Males With Diabetic NeuropathyThe Efficacy and Safety Profile of Capsaicin 8% Patch Versus 5% Lidocaine Patch in Patients With Diabetic Peripheral Neuropathic Pain: a Randomized, Placebo-controlled Study of South Asian Male PatientsNCT04238208
Management of pharyngeal residues in neurogenic dysphagia: Another clearing effect of capsaicin after cough stimulation with cayenne aersosolManagement of pharyngeal residues in neurogenic dysphagia: Another clearing effect of capsaicin after cough stimulation with cayenne aersosolDRKS00020893
Capsaicin for the Treatment of Cannabinoid Hyperemesis SyndromeCapsaicin for the Treatment of Cannabinoid Hyperemesis SyndromeNCT04283292
The Efficacy of topical Capsaicin in the management of painful diabetic peripheral neuropathy: A unicenter double-blind, randomized clinical trialThe Efficacy of topical Capsaicin in the management of painful diabetic peripheral neuropathy: A unicenter double-blind, randomized clinical trialPACTR202003714748946
Effects of capsaicin on onset time of swallowing in stroke patients with dysphagiaEffects of capsaicin on onset time of swallowing in stroke patients with dysphagiaChiCTR2000031919
Central Sensitization Modulates Low Back Muscle Recruitment Patterns and Perceived Effort During Static Low Back Stabilizing ExercisesThe comparison of the effect of central sensitization evoked by topical capsaicin cream versus non-sensitizing placebo cream on the muscle activation patterns in the lumbar spine and perceived effort during static low back stabilizing exercises in young healthy subjects.ACTRN12612000039886
Cooling for reducing treatment-related pain when applying capsaicin 8% patchEUCTR2011-002264-25-AT
Motor Unit Abnormalities After Experimentally Induced SensitizationEvaluation of Motor Unit Abnormalities After Experimentally Induced Sensitization Using Capsaicin: A Randomized, Double-Blinded, Placebo-Controlled StudyNCT04361149
Comparing the effect of topical Wishca, Diclofenac and Capsaicin cream in knee osteoarthritisComparison the therapeutic effect of topical Wishca,Diclofenac and Capsaicin in patient with knee OsteoarthritisIRCT20130228012654N2
Capsaicin for Post-stroke DysphagiaCapsaicin for Post-stroke DysphagiaNCT04470752
The Effect of Capsaicin-induced Pain on Homeostatic Plasticity in Healthy Human ParticipantsThe Effect of Capsaicin-induced Pain on Homeostatic Plasticity in Healthy Human ParticipantsNCT04485689
Capsaicin supplementation combined with aerobic exercise on food intake in young adultsInfluence of acute capsaicin supplementation combined with aerobic exercisedietary intake of physically active young peopleRBR-5pckyr
Capsaicin for Cerebral Perfusion Augmentation.Dose-Escalation and Safety of Capsaicin for Cerebral Perfusion Augmentation. A Pilot StudyNCT04545892
Double-blind Trial of Mannitol Cream to Block the Effect of Capsaicin CreamDouble-blind Trial of Mannitol Cream to Block the Effect of Capsaicin CreamNCT01963910
Study With Two Capsaicin Topic Treatments in Diabetic Neuropathy.Study of Efficacy and Non-inferiority, With Two Capsaicin Topic Treatments, for the Moderate to Severe Pain in Diabetic Neuropathy.NCT05029297
Clinical Study comparing effectiveness of Topical Capsaicin and Oral Pregabalin in treating Diabetic Neuropathy.Comparative study of efficacy between Topical Capsaicin 0.025% w/w, Capsaicin 0.075% w/w, and Oral Pregabalin in Diabetic Peripheral Neuropathy- A Randomized Controlled Clinical Trial. - CAPRECTRI/2021/05/033861
Comparison of Qutenza (8% Capsaicin) With a Low-dose Capsaicin for Treatment of Nerve Pain After SurgeryAn Interventional, Phase III, Double-blind, Randomized, Controlled, Parallel-group, Multi-site, Clinical Trial Evaluating the Efficacy and Safety of Qutenza® in Subjects With Post-surgical Neuropathic PainNCT04967664
Capsaicin 8% patch treatment in non-freezing cold injury (NFCI)Capsaicin 8% patch Qutenza treatment in non-freezing cold injury (NFCI): a clinical trial of repeated patch applications for pain relief and nerve regenerationISRCTN11180128
Capsaicin Cream as an Adjunctive Therapy for Nausea and Vomiting of PregnancyTrial of Capsaicin Cream as an Adjunctive Therapy for Nausea and Vomiting of Pregnancy: A Pilot InvestigationNCT05098067
Capsaicin in digital osteoarthritis versus control : a randomized studyCapsaicin in digital osteoarthritis versus control : a randomized study - PHRC IR 2022 MATHIEUCTIS2024-511159-16-00
A Study to Evaluate Laser Speckle Contrast Imaging to Assess Changes in Chemical Agent-Induced Skin Blood Flow in Healthy Participants (MK-0000-420)A Pilot Study to Evaluate the Use of Laser Speckle Contrast Imaging on Changes in Dermal Blood Flow Induced by Intradermal Capsaicin and Topical AITC in Healthy ParticipantsNCT06809569
Investigation of capsaicin supplement and High Intensity resistance Circuit Training (HIRCT) on serum hemorheological indices, oxidative-antioxidant status, and military performance in cold and mountainous climatesAntioxidant Properties of Capsaicin along with High Intensity Resistance Circuit Training Contributes to the Redox and Hemorheological Adaptation during Cold Exposure StressIRCT20240513061779N1
Topical capsaicin in burning mouth syndromeThe efficacy of topical capsaicin in reducing symptoms in patients with burning mouth syndromeACTRN12608000235303
A comparison of the pain control efficacy of Acetaminophen and capsaicin with a placebo in patients with orthodontic dental painPain control in orthodontic mechanotherapy - A Randomized Controlled TrialCTRI/2017/02/007846
Ethnic Differences in Response to Topical Capsaicin: A Psychophysical Study on Healthy SubjectsEthnic Differences in Response to Topical Capsaicin: A Psychophysical Study on Healthy SubjectsNCT00655811
Sensory Function After Wound Instillation of CapsaicinCutaneous Sensory Function After Wound Instillation of Capsaicin During Groin Hernia RepairNCT00583180
Study of Three Capsaicin Dermal Liquid Formulations on Epidermal Nerve Fiber Immunostaining and Sensory FunctionA Randomized, Controlled, Single-Blind Study to Investigate the Effect of Three Capsaicin Dermal Liquid Formulations on Epidermal Nerve Fiber Immunostaining and Sensory Function In Healthy VolunteersNCT00528216
Topical Capsaicin 0.025% as a treatment for Achilles tendinopathy. A prospective, double blinded, randomised controlled trial with multiple outcome measures.Topical Capsaicin 0.025% as a treatment for Achilles tendinopathy. A prospective, double blinded, randomised controlled trial with multiple outcome measures.EUCTR2006-005471-18-GB
The effects of resistant starch in combination with protein and capsaicin on energy-metabolism and satiety measured in a respiration chamberThe effects of resistant starch in combination with protein and capsaicin on energy-metabolism and satiety measured in a respiration chamber - Effects of RS, protein and capsaicinNL-OMON30505
Effects of Capsaicin on the Structure, Distribution, and Function of Cutaneous Small Nerve Fibers in Psoriatic SkinEffects of Capsaicin on the Structure, Distribution, and Function of Cutaneous Small Nerve Fibers in Psoriatic SkinNCT00697034
Efficacy Study on Symptomatic Control of Patient With Knee Osteoarthritis Between 0.0125% of Capsaicin to PlaceboEfficacy Study on Symptomatic Control of Patient With Knee Osteoarthritis Between 0.0125% of Capsaicin to PlaceboNCT00471055
Response of Topical Capsaicin in Alopecia AreataPerifollicular Nerves in Alopecia Areata: Response to Topical CapsaicinNCT00176969
Capsaicin to Control Pain Following Third Molar ExtractionEvaluation of Vanilloid Receptor Inactivation for Preemptive AnalgesiaNCT00088686
Pilot Study of High-Concentration Capsaicin Patches in the Treatment of Painful HIV-Associated NeuropathyAn Open-Label Pilot Study of High-Concentration Capsaicin Patches in the Treatment of Painful HIV-Associated NeuropathyNCT00061152
Pilot Study of High-Dose Capsaicin Patches to Treat Postherpetic Neuralgia PainA Double-Blind Controlled Pilot Study of High-Dose Capsaicin Patches in the Treatment of Pain Associated With Postherpetic NeuralgiaNCT00034710
Capsaicin to Control Pain Following Third Molar ExtractionEvaluation of Vanilloid Receptor Inactivation for Preemptive AnalgesiaNCT00008476
Capsaicin Lozenges in Treating Patients With Mucositis Caused by Radiation TherapyPhase III Comparison of Oral Capsaicin Lozenge Versus Placebo Lozenge for Radiation-Induced MucositisNCT00003610
Phase I/II Randomized, Placebo-Controlled Study of Capsaicin for Interstitial Cystitis and Vulvar VestibulitisNCT00004316
The effects of resistant starch, protein and capsaicin on energy-expenditure, hormones and satietyThe effects of resistant starch, protein and capsaicin on energy-expenditure, hormones and satiety - Effects of RS, protein and capsaicin.NL-OMON29901
Cervical Capsaicin for Labor Induction and Pain ReliefCervical Capsaicin for Labor Induction and Pain ReliefNCT00771511
Trial to Evaluate the Efficacy of Topical Capsaicin to Reduce Pain and Improve Health-related Quality of Life in Adults With Chronic Myofascial Neck PainDouble-blinded, Cross-over Randomized Controlled Trial to Evaluate the Efficacy of Topical Capsaicin to Reduce Pain and Improve Health-related Quality of Life in Adults With Chronic Myofascial Neck PainNCT00795106
A Study to Investigate the Tolerability and Effects on Epidermal Nerve Fiber Density of Multiple Low-Concentrations of NGX-1998 in Healthy VolunteersA Randomized, Single Blind Study to Investigate the Tolerability and Effects on Epidermal Nerve Fiber Density of Multiple Low-Concentrations of Capsaicin Topical Liquid NGX-1998 in Healthy VolunteersNCT00912262
Efficacy of Capsaicin Nasal Spray in Non-allergic rhinitis : A pilot studyEfficacy of Capsaicin Nasal Spray in Non-allergic rhinitis : A pilot studyTCTR20241008002
Comparing the outcomes of Capsaicin cream with mometasone cream in the treatment of Macular AmyloidosisComparing the outcomes of 0.025% Capsaicin cream with 0.1% mometasone cream in the treatment of Macular Amyloidosis lesionsIRCT20230307057646N3
Brain and brainstem activation following duodenal nociceptive stimulation with capsaicin, an exploratory high-resolution fMRI study in healthy volunteers.Brain and brainstem activation following duodenal nociceptive stimulation with capsaicin, an exploratory high-resolution fMRI study in healthy volunteers. - fMRI and visceral perceptionNL-OMON47774
Research on the Regulatory Effect and Mechanism of Capsaicin Smearing on Dysphagia in Patients with Consciousness DisordersResearch on the Regulatory Effect and Mechanism of Capsaicin Smearing on Dysphagia in Patients with Consciousness DisordersChiCTR2500096779
Acute effects of capsaicin on energy expenditure, fat oxidation and satiety in negative energy balanceAcute effects of capsaicin on energy expenditure, fat oxidation and satiety in negative energy balance - Acute effects of capsaicinNL-OMON36708
A double-blinded, randomized, crossover clinical study to assess the efficacy of Qutenza (capsaicin 8% patches) for the reduction of site pain caused by continuous subcutaneous infusion of Remodulin (treprostinil sodium), in Pulmonary Arterial Hypertension Patients - Efficacy of capsaicin 8% patches in Pulmonary Arterial HypertensionA double-blinded, randomized, crossover clinical study to assess the efficacy of Qutenza (capsaicin 8% patches) for the reduction of site pain caused by continuous subcutaneous infusion of Remodulin (treprostinil sodium), in Pulmonary Arterial Hypertension Patients - Efficacy of capsaicin 8% patches in Pulmonary Arterial HypertensionEUCTR2011-001312-59-GB
Understanding chronic coughComparing Capsaicin Dose-Response CurvesISRCTN65122210
Efficacy of Topical Capsaicin Cream for Stable AnginaA Randomized, Placebo-Controlled, Cross-Over Study to Assess the Safety and Efficacy of TOPical CAPsaicin With Stable Angina (TOPCAP)NCT01231750
Neuro-immunological Analysis of Idiopathic Rhinitis Patients and Controls Treated With Capsaicin.Neuro-immunological Analysis of Idiopathic Rhinitis Patients and Controls Treated With Capsaicin.NCT01223820
A clinical trial to study the efficacy and safety of topical gel containing fixed dose combination of Amitriptyline, Lidocaine and Capsaicin in treatment of neurogenic pain associated with localized peripheral neuropathies.A open-label, multicenter, non-randomized, prospective, phase III clinical trial to study the Efficacy and Safety of topical gel containing fixed dose combination of Amitriptyline, Lidocaine and Capsaicin in treatment of neurogenic pain associated with localized peripheral neuropathies.CTRI/2010/091/001458
A phase IV single-centre study to evaluate the topical administration of capsaicin cream (0.075%) as a healthy volunteer model of neuropathic pain. - NDA phase IV single-centre study to evaluate the topical administration of capsaicin cream (0.075%) as a healthy volunteer model of neuropathic pain. - NDEUCTR2009-018056-42-IT
Efficacy of Topical Capsaicin on Chronic Neck PainEfficacy of Topical Capsaicin on Chronic Neck Pain ; Double-blinded Randomized TrialNCT01200745
Acute Response Capsaicin Flare StudyA Double Blind, Randomized, Placebo-Controlled, Third-Party Open, Modified Cross-Over Study To Examine The Acute Effect Of PF-04427429 On Capsaicin Flare Response In Healthy Volunteers Using EMLA Cream As Positive ControlNCT01147432
Capsaicin Nanoparticle in Patient With Painful Diabetic NeuropathyStudy of Topical Preparation of Capsaicin Nanoparticle in Patient With Painful Diabetic NeuropathyNCT01125215
To investigate the acute effects of different doses of chilli ingestion on blood glucose, insulin, blood vessel function and energy expenditure.A radomised crossover study to determine the doses at which capsaicin affects blood glucose and insulin in healthy volunteers.ACTRN12609000890235
Efficacy and Safety Study of Topical Capsaicin in Painful Diabetic NeuropathyA Randomized, Crossover, Double Blinded, Placebo Controlled Trial of Topical Capsaicin in Treatment of Painful Diabetic NeuropathyNCT00993070
A clinical Trial in adult patients suffering from Neuralgia due to diabetes, chemotherapy or shingles. Clinical trial is to study efficacy, safety and tolerability of Amitriptyline 4% + Ketamine 2% Cream in comparison to Capsaicin Cream 0.025%, (reference product).A comparative single blind, Parallel group, non-crossover, multi-centric clinical trial of Amitriptyline 4% + Ketamine 2 % Cream in patients having Neuralgia due to diabetes, chemotherapy or shingles.CTRI/2009/091/000688
Qutenza 8% Capsaicin Topical System for the Treatment of Neuropathic Axial Lower Back Pain and Lumbosacral RadiculopathyQutenza 8% Capsaicin Topical System for the Treatment of Neuropathic Axial Lower Back Pain and Lumbosacral Radiculopathy: a Prospective Study.NCT06540456
Topical treatment of nerve pain arising from artery-to-vein connections in patients with kidney failureThe role of Qutenza (topical capsaicin 8%) in treating neuropathic pain from arteriovenous fistulae in patients with end stage renal failure - Qutenza for painful fistulae v1.0EUCTR2014-002266-71-GB
Effects of repeated aural stimulation on substance P concentration in blood, saliva and sputum and swallowing function in healthy subjects and patients with dysphagia: a phase 1-2 studyEffects of repeated aural stimulation on substance P concentration in blood, saliva and sputum and swallowing function in healthy subjects and patients with dysphagia: a phase 1-2 study - A phase 1-2 study of effects of capsaicin ointment on substance P and swallowingJPRN-jRCTs061180080
Prophylactic effects of repeated aural stimulation with capsaicin ointment on development of pneumonia in elderly patients: a phase 2 RCT studyProphylactic effects of repeated aural stimulation with capsaicin ointment on development of pneumonia in elderly patients: a phase 2 RCT study - A phase 2 RCT study with capsaicin ointmentJPRN-jRCTs061180088
Chest Pain Perception and Capsaicin Sensitivity in Patients With Acute Cardiac IschemiaChest Pain Perception and Capsaicin Sensitivity in Patients With Acute Cardiac IschemiaNCT02346916
Chest Pain Perception and Capsaicin SensitivityChest Pain Perception and Capsaicin SensitivityNCT02346903
The effects of capsaicin and tea on sodium and water homeostasis as measured by osmoregulation and blood pressure.The effects of capsaicin and tea on sodium and water homeostasis as measured by osmoregulation and blood pressure. - PEPPER studyNL-OMON40691
Comparison of Cold Dry Air Exposure, Discs and CapsaicinComparison of Cold Dry Air Exposure, Hyperosmolar Sponge and Capsaicin Nasal Spray for Objective Evaluation of Nasal HyperreactivityNCT02334605
ELABORATION OF A PATIENT-FRIENDLY TREATMENT STRATEGY WITH CAPSAICIN NASAL SPRAY IN PATIENTS WITH IDIOPATHIC RHINITISELABORATION OF A PATIENT-FRIENDLY TREATMENT STRATEGY WITH CAPSAICIN NASAL SPRAY IN PATIENTS WITH IDIOPATHIC RHINITISEUCTR2014-003914-10-BE
Capsaicin-induced Muscle Pain in HumansCapsaicin-induced Muscle Pain in Humans: From Investigating Central Pain Processing to Developing Clinical ApplicationsNCT02377180
Capsaicin 8% Patch for Spinal Cord Injury Neuropathic PainCapsaicin 8% Patch for Spinal Cord Injury Neuropathic PainNCT02441660
Phase II Trial of capsaicin gel application for prevent paclitaxel-induced peripheral neuropathyPhase II Trial of capsaicin gel application for prevent paclitaxel-induced peripheral neuropathyTCTR20150626002
Phase II Trial of capsaicin gel application for prevent oxaliplatin-induced peripheral neuropathyPhase II Trial of capsaicin gel application for prevent oxaliplatin-induced peripheral neuropathyTCTR20150720002
Effect of capsaicin infusion on esophageal mucosal integrity * a role for TRPV1-mediated neuropeptides?Effect of capsaicin infusion on esophageal mucosal integrity * a role for TRPV1-mediated neuropeptides? - Capsaicin and mucosal integrityNL-OMON42198
Accelerating effect of applying capsaicin-containing film on the swallowing reflex - a double blind cross-over study -Accelerating effect of applying capsaicin-containing film on the swallowing reflex - a double blind cross-over study - - Accelerating effect of a applying capsaicin-containing film on the swallowing reflexJPRN-UMIN000008946
A study to investigate the pharmacodynamics, safety and tolerability of cutaneous capsaicin in healthy adult subjects.A study to investigate the pharmacodynamics, safety and tolerability of cutaneous capsaicin in healthy adult subjects. - Development of a nociceptive test battery - capsaicin modelsNL-OMON37233
Comparison of different Capsaicin doses and their effects on nerve fibres in the skinEpidermal Nerve Fibre Density Reduction as a Function of Application Time of topical high-dose and low-dose Capsaicin - Capsaicin dose and reduction of ENF densityEUCTR2012-002406-46-AT
Mechanisms of Capsaicin Treatment in Idiopathic Rhinitis Patients and ControlsUnraveling the Mechanisms of Capsaicin Treatment in Idiopathic Rhinitis Patients and Controls by Measuring Mucosal Potentials in the Nose.NCT01862523
fMRI and Visceral Perception Upon Capsaicin InfusionBrain and Brainstem Activation Following Duodenal Nociceptive Stimulation With Capsaicin, an Exploratory High-resolution fMRI Study in Healthy VolunteersNCT02551029
Translational trial to explore the pharmacodynamic effects of multiple oral dose administrations of tapentadol PR, pregabalin, and combinations of both in an intradermal capsaicin hypersensitization model in healthy subjects.Translational trial to explore the pharmacodynamic effects of multiple oral dose administrations of tapentadol PR, pregabalin, and combinations of both in an intradermal capsaicin hypersensitization model in healthy subjects. - Pharmacodynamic study with tapentadol PR and pregabalinNL-OMON42611
Pain Thresholds Under High-dose Topical CapsaicinHeat-, Cold-, and Mechanical Pain Thresholds Under Exposition of High Dose Topical CapsaicinNCT02570841
Efficacy of 0.0125% Capsaicin Patch at Acupuncture Point for Pain Relief in Knee OsteoarthritisEfficacy of 0.0125% Capsaicin Patch at Acupuncture Point for Pain Relief in Knee OsteoarthritisTCTR20141111001
Elaboration of Patient-friendly Treatment Strategy With Capsaicin Nasal Spray in Patients With Idiopathic RhinitisElaboration of Patient-friendly Treatment Strategy With Capsaicin Nasal Spray in Patients With Idiopathic RhinitisNCT02288156
Intranasal Capsaicin Treatment for Non-Allergic Irritant RhinitisDouble-Blinded Randomized Prospective Trial of Intranasal Capsaicin Treatment for Non-Allergic Irritant RhinitisNCT02493257
Effect of capsaicin ointment on nausea and vomitingEffect of capsaicin ointment in K-K9 point, capsaicin ointment in K-D2 point and placebo ointment (Vaseline) in K-K9 point on nausea and vomiting during and postoperative cesarean section with spinal anesthesiaIRCT2014062918269N1
DSP-2230 Capsaicin and UVB Challenge StudyA randomised, double-blind, placebo-controlled, four-way crossover, two-part study investigating the pharmacodynamic effect of DSP-2230 using the ID Capsaicin and UVB models in healthy male subjects, using pregabalin and ibuprofen lysine as positive controls.ISRCTN80154838
The Effect of Thermal Stimuli on the Response to Intradermal Capsaicin in Healthy Male ParticipantsThe effect of thermal stimuli on the outcomes spontaneous pain, flare, allodynia and hyperalgesia in response to intradermal capsaicin in healthy male participantsACTRN12613000004763
Effect Of PF-06305591 On Capsaicin And Capsaicin/Heat-Induced Neurogenic FlareA Double Blind, Randomized, Placebo-Controlled, Third-Party Open, Cross-Over Study To Examine The Effect Of PF-06305591 On Capsaicin And Capsaicin/Heat-Induced Neurogenic Flare In Healthy VolunteersNCT01797796
The Use of Capsaicin Challenge for Diagnosis, Monitoring and Follow-up of Chronic Cough.The Use of Capsaicin Challenge for Diagnosis, Monitoring and Follow-up of Chronic Cough.NCT01807832
The assessment of local response to topical menthol gel and capsaicin gel applied with and without microneedle pretreatmentThe assessment of local response to topical menthol gel and capsaicin gel applied with and without microneedle pretreatment on the forearm skin of 60 healthy adult volunteersACTRN12613000319774
The Effect of Ablation of Epidermal Nerve Fibers Using Capsaicin CreamThe Effect of Ablation of Epidermal Nerve Fibers Using 0.1% Capsaicin Cream on Spontaneous Cutaneous Burning Pain, Tactile Hyperalgesia, and Thermal Hyperalgesia: A Controlled, Masked Trial With an N of 1NCT01883102
Clinical trial to investigate the analgesic effect of Aspirin during the application of 8% capsaicin patchA prospective randomized, double blind, placebo-controlled, cross-over study to investigate the analgesic effect of Aspirin® to prevent the pain during the treatment with capsaicin patch 8% (Qutenza®) - Clinical trial to investigate the analgesic effect of Aspirin during the application of 8% capsaicinEUCTR2012-002947-74-AT
To evaluate Safety and Efficacy of Diclofenac Diethylamine Gel with Capsaicin, Methyl Salicylate and Menthol In Painful Musculoskeletal Conditions.A Multi-center, Prospective, Open-label, Randomized, Active-Controlled, Parallel-Group Clinical Study of Safety and Efficacy of Diclofenac Diethylamine Gel with Capsaicin, Methyl Salicylate and Menthol With Voveran® Thermagel� (Diclofenac Diethylamine Gel with Capsaicin, Methyl Salicylate and Menthol) In Painful Musculoskeletal Conditions.CTRI/2013/06/003751
Does a two-day pretreatment with capsaicin reduce postoperative hyperalgesia and pain in surgical patientsDoes a two-day pretreatment with capsaicin reduce postoperative hyperalgesia and pain in surgical patientsA prospective, randomized, double-blind, placebo-controlled, parallel group, single-center clinical trial on the effects of preoperative capsaicin-induced TRPV1-fiber desensitization on postoperative LTP-like pain plasticity in surgical patients - CaPsaPPPEUCTR2015-003208-22-AT
Comparison of NSAID Patch Given in Monotherapy and NSAID Patch in Combination With Transcutaneous Electric Nerve Stimulation, Heating Pad, or Topical Capsaicin in the Treatment of Patients With Myofascial Pain Syndrome of the Upper Trapezius: A Pilot StudyNCT01884116
Painthresholds under high-dose topical CapsaicinHeat-, Cold-, and Mechanical Painthresholds under exposition of high dose topical CapsaicinEUCTR2013-002546-36-AT
Capsaicin on Salty Gustatory CorticesEffects of Capsaicin on Salty Gustatory Cortices in HumanNCT01974037
CAPSAICIN Trial: Assessing Capsaicin as a Chemopreventive Agent for Prostate CancerCAPSAICIN Trial: A Prospective Study of Capsaicin in Subjects With Clinically Localized Prostate Cancer Undergoing Active Surveillance or Radical ProstatectomyNCT02037464
ClUDo: The Clinical Utility of Capsaicin Dose Response Curves to Discriminate Cough Hyper-responsivenessThe Clinical Utility of Capsaicin Dose Response Curves to Discriminate Cough Hyper-responsivenessISRCTN23684347
The Efficacy of Capsaicin Sensitivity Testing in Patients With Irritable Larynx SyndromeThe Efficacy of Capsaicin Sensitivity Testing in Patients With Irritable Larynx SyndromeNCT02065128
Effects of aural repeated stimulation with ointment containing capsaicin on swallowing exercises in patients with dysphagiaEffects of aural repeated stimulation with ointment containing capsaicin on swallowing exercises in patients with dysphagia - Effects of aural repeated stimulation with ointment containing capsaicin on swallowing exercises in patients with dysphagiaJPRN-UMIN000013444
The effect of capsaicin for dysphagia and globus sensation - using Tissue Doppler Imaging -The effect of capsaicin for dysphagia and globus sensation - using Tissue Doppler Imaging - - The effect of capsaicin for dysphagia and globus sensation - using Tissue Doppler Imaging -JPRN-UMIN000014403
Study of Capsaicin Patch for the Management of Peripheral Neuropathic PainEfficacy and Safety of 0.625% and 1.25% Capsaicin Patch in the Management of Peripheral Neuropathic Pain ; Early Phase II, Multi-center, Randomized, and Semi-double Blind Controlled Clinical TrialNCT02228928
Effect of gabapentin versus capsaicin on heart rate variability in patients with diabetic painful peripheral neuropathyEffect of gabapentin versus capsaicin on heart rate variability in patients with diabetic painful peripheral neuropathy: a double blinded randomized clinical trialIRCT201308179014N18
Quantitative Ultrasound Response of CapsaicinQuantitative Response of Healthy Muscle Following the Induction of CapsaicinNCT03944889
Study of swallowing reflex promoting effect due to capsaicin intake for swallowing disorders of the nervous intractable disease patientStudy of swallowing reflex promoting effect due to capsaicin intake for swallowing disorders of the nervous intractable disease patient - The swallowing reflex promoting effect of nerve intractable disease patients with capsaicinJPRN-UMIN000019243
Capsaicin Patches In Knee Osteoarthritis In Obese PatientsEfficacy And Safety Of High Concentration Capsaicin Patches In Knee Osteoarthritis In Obese Patients: A Randomized Prospective Double Blind Placebo Controlled StudyNCT03153813
Capsaicin in Treatment of Rhinogenic HeadacheThe Role of Topical Capsaicin in Treatment of Rhinogenic HeadacheNCT03330639
The Effect of Injection Site Cooling on Pain Experienced After the Administration of CNTX-4975-05 Into the KneeA Phase 1b Study to Characterize the Effect of Injection Site Cooling on Pain Experienced After CNTX-4975-05 (Trans-capsaicin) Intra-articular and Capsaicin Intradermal Injections in Healthy Volunteers and Subjects With Bilateral Painful Knee OsteoarthritisNCT03472677
exploratory study on the effects of capsaicin on hospitalized patient with oropharyngeal dysphagiaexploratory study on the effects of capsaicin on hospitalized patient with oropharyngeal dysphagia - the effects of capsaicinJPRN-UMIN000032168
Treatment of nerve pain in patients with diabetes with a capsaicin (chilli pepper) patch (skin plaster).Pain relief with disease modification by Capsaicin 8% patch: a clinical study in Diabetic Peripheral Neuropathy - Capsaicin 8% patch: a clinical study in Diabetic Peripheral NeuropathyEUCTR2017-004746-17-GB
ATP and Capsaicin Cough Provocation Test in Chronic Cough and BronchiectasisAdenosine Triphosphate and Capsaicin Cough Provocation Test for Identifing Patients With Chronic Cough Who Have Differential Responses to Purinergic Receptor Antagonists: a Randomized, Cross-over, Single-blind TrialNCT03638063
A study to compare the comfort and ease of use of 5 different treatment regimens for trans-capsaicin injection into the knee in patients with moderate to severe osteoarthritis knee-painAn Open-label, 8 Week Study to Compare the Comfort and Ease of Use of Five Different Treatment Regimens for CNTX 4975-05 Intra-articular Injection in Subjects with Chronic, Moderate-to-Severe Osteoarthritis Knee PainEUCTR2018-003094-10-DE
Reduction in Pain Intensity Following IV or Oral Pain-relieving ProductsA Randomized, Placebo-Controlled, Double-Blind, Two-Part, Cross-over Study in Healthy Adult Male Subjects to Compare the Reduction in Pain Intensity After Single-Dose Administration of Intravenous or Oral Acetaminophen and Intravenous Morphine by Using UVB Burn and Intradermal Capsaicin Experimental Pain ModelsNCT02678416
The Capsaicin 8% patch for pain relief in diabetic peripheral neuropathyPain relief with disease modification by Capsaicin 8% patch: a clinical study in diabetic peripheral neuropathy.ISRCTN14254122
Evaluation in the Treatment of Neuropathic Pain Post Breast SurgeryMulticentric, Open, Randomized Study Comparing Topical Treatment by Patch of Capsaicin to 8% (Qutenza) to Pregabalin Oral in the Early Treatment of Neuropathic Pain After Primary Surgery for Breast CancerNCT03794388
CAPSAICIN CHALLENGE STUDY TO INVESTIGATE THE POTENTIAL ANALGESIC EFFECTS OF V113741 IN HEALTHY MALE SUBJECTSCAPSAICIN CHALLENGE STUDY TO INVESTIGATE THE POTENTIAL ANALGESIC EFFECTS OF V113741 IN HEALTHY MALE SUBJECTSEUCTR2009-014908-57-NL
Influence on cough and airway symptoms by oral capsaicin (capscium oleoresin) – a phase II, randomised, placebo-controlled clinical study in patients with chronic idiopathic coughInfluence on cough and airway symptoms by oral capsaicin (capscium oleoresin ) – a phase II, randomised, placebo-controlled clinical study in patients with chronic idiopathic coughEUCTR2016-004463-39-SE
The relationship between methacholine induced cough response, cough receptor sensitivity to capsaicin and a sensation of irritation in the throatThe relationship between methacholine induced cough response, cough receptor sensitivity to capsaicin and a sensation of irritation in the throat - The relationship between methacholine induced cough response, cough receptor sensitivity to capsaicin and a sensation of irritation in the throatJPRN-UMIN000035303
Sickle Cell Pain: Intervention With Capsaicin ExposureSafety and Feasibility of High-Dose Topical Capsaicin for the Treatment of Neuropathic Pain in Pediatric Sickle Cell DiseaseNCT03899246
Study on the effects of capsaicin on the incidence rate of gestational diabetes mellitus and intervention research in ChongqingStudy on the effects of capsaicin on the incidence rate of gestational diabetes mellitus and intervention research in ChongqingChiCTR-TRC-12002193
Capsaicin Energy Expenditure and Glucose MetabolismCapsaicin Consumption on Resting Energy Expenditure and Glucose MetabolismNCT03859583
Capsaicin pain model with topical 1% ethanolic capsaicin solutionCapsaicin pain model with topical 1% ethanolic capsaicin solution - 1% capsaicin solution pain modelNL-OMON48384
Qutenza for Critical Ischaemia in End Stage Renal FailureThe Role of Qutenza (Topical Capsaicin 8%) in Treating Neuropathic Pain From Critical Ischaemia in Patients With End-stage Renal FailureNCT01704339
Topical Capsaicin for Cyclical VomitingTopical Capsaicin Cream for Treatment of Suspected Cyclical Vomiting SyndromesNCT03223350
High Definition Transcranial Direct Current Stimulation Motor Cortex Versus InsulaThe Effects of High Definition Transcranial Direct Current Stimulation Over Primary Motor Cortex Versus Insular Cortical Targets on Experimental Capsaicin Induced Hyperalgesia and Pain in Healthy VolunteersNCT03216707
Prophylactic effects of aural stimulation with capsaicin ointment on pneumonia in elderly patientsProphylactic effects of aural stimulation with capsaicin ointment on pneumonia in elderly patients - Prophylactic effects of aural stimulation with capsaicin ointment on pneumonia in elderly patientsJPRN-UMIN000026879
Topical Use of 20% Beta Caryophyllene Alone And In Combination With 0.025% Capsaicin for Pain Caused by Osteoarthritis Of The KneeRandomized, Double Blind, Placebo Controlled Crossover Trial With Open Label Extension Of Topical 20% Beta Caryophyllene Alone And In Combination With 0.025% Capsaicin In The Treatment Of Pain Caused By Osteoarthritis Of The KneeNCT03152578
Investigating Neuronal responses by assessing Cough in AsthmaInvestigating neuronal responses by assessing capsaicin evoked cough responses in an allergen challenge model of asthma: a randomised cross-over studyISRCTN79930571
The questionnaire survey in the effect of capsaicin intake for swallowing disorders of the nervous intractable disease patientThe questionnaire survey in the effect of capsaicin intake for swallowing disorders of the nervous intractable disease patient - Questionnaire survey at the time of capsaicin intake to nerve intractable disease patientJPRN-UMIN000020525
Capsaicin + diclofenac gel in acute back pain or neck painA randomized, controlled multi-centre parallel group study to assess the efficacy and safety of multiple doses of a topically applied combination containing diclofenac 2% + capsaicin 0.075% (2 g formulation per application; 2-times daily for 5 days) compared to placebo, as well as to diclofenac 2% and capsaicin 0.075% in patients with acute back or neck painEUCTR2015-000404-25-DE
Effect of topical capsaicin versus cryotherapy on clinical sign in patients with verruca vulgarisEffect of topical capsaicin versus cryotherapy on clinical sign in patients with verruca vulgaris: a randomized clinical trialIRCT201601179014N89
The relationship between the cough response to bronchoconstriction induced by the methacholine provocation using the astographmethod and cough reflex sensitivity to inhaled capsaicin in healthy subjectsThe relationship between the cough response to bronchoconstriction induced by the methacholine provocation using the astographmethod and cough reflex sensitivity to inhaled capsaicin in healthy subjects - The relationship between the cough response to bronchoconstriction induced by the methacholine provocation and cough reflex sensitivity to inhaled capsaicin in healthy subjectsJPRN-UMIN000020804
The effect of low intensity exercise intervention with and without capsaicin analogues on physical activity, fitness, body composition and psychological factors in community dwelling older adultsThe effect of low intensity exercise intervention with and without capsaicin analogues on physical activity, fitness, body composition and psychological factors in community dwelling older adults - The effect of low intensity exercise intervention with and without capsaicin analogues in community dwelling older adultsJPRN-UMIN000021909
A Human Experimental Model for Neuropathic Pain Using Combined Application of Capsaicin and Local AnestheticsNCT01540877
Effects of High-concentration Topical Capsaicin on Histaminergic and Non-histaminergic ItchThe Role of Pre-established Skin Inflammation on the Susceptibility to Histamine and Cowhage-induced Itch in Healthy HumansNCT02769910
CAPSAICIN PATCH 8% FOR THE TREATMENT OF PERSISTENT PAIN AFTER INGUINAL HERNIOTOMYCAPSAICIN PATCH 8% FOR THE TREATMENT OF PERSISTENT PAIN AFTER INGUINAL HERNIOTOMYEUCTR2012-001540-22-DK
A Study to Evaluate Efficacy and Safety of a Single Application of Capsaicin 8%Transdermal Delivery System Compared to Placebo in Reducing Pain Intensity in Subjects With Painful Diabetic Peripheral Neuropathy (PDPN)A Phase III, Double-blind, Randomized, Placebo-controlled, Multicenter Study Evaluating the Efficacy and Safety of QUTENZA® in Subjects With Painful Diabetic Peripheral NeuropathyNCT01533428
Drug effect on tooth sensitivity after bleachingEffect of systemic capsaicin on the prevention of tooth sensitivity after in-office bleachingIRCT2015122825729N1
A Study of the Effects of Topical Capsaicin in the Treatment of Provoked VestibulodyniaNCT02854670
The influence of topical appliqued capsaicin on the intensity and quality of chronic neuropathic painThe influence of topical appliqued capsaicin on the intensity and quality of chronic neuropathic painDRKS00011198
Neuromodulation of Lidocaine and Capsaicin Cream Effects on Pain ExperienceNeuromodulation of Placebo and Nocebo EffectsNCT03102710
Comparison of the Bioavailability of Diclofenac in a Combination Product (Diclofenac 2% + Capsaicin 0.075% Topical Gel) With Two Diclofenac Only Products, Diclofenac Mono Gel 2% and Voltarol® 12 Hour Emulgel 2.32% Gel, in Healthy VolunteersA SINGLE CENTER, MULTIPLE DOSE, OPEN-LABEL, RANDOMIZED, THREE-PERIOD CROSSOVER STUDY TO DETERMINE THE RELATIVE BIOAVAILABILITY OF DICLOFENAC IN THE TOPICAL GEL COMBINATION PRODUCT (DICLOFENAC 2% + CAPSAICIN 0.075%) COMPARED TO DICLOFENAC MONO GEL 2% AND VOLTAROL® 12 HOUR EMULGEL 2.32% GEL IN AT LEAST 42 HEALTHY MALES AND FEMALESNCT03074162
0.075% Capsaicin Lotion for the Treatment of Painful Diabetic Neuropathy: A Randomized, Double- Blind, Crossover, Placebo-Controlled TrialTopical therapy may provide additional benefit in patients with painful diabetic neuropathy (PDN).This study was conducted to study the safety and efficacy of0.075% capsaicin lotion in this conditionTCTR20170407001
Ibuprofen Gel or Capsaicin Cream for my Painful Knee Osteoarthritis?Identifying Treatment Responders to a Topical Non-steroidal Anti-inflammatory Drug (NSAID) or Topical Capsaicin in Painful Knee Osteoarthritis: A Pilot Series of N-of-1 TrialsNCT03146689
Survey of a representative sample of patients after topicala) capsaicin 8% therapyb) lidocaine 5% therapyc) botulinum toxin A injectionSurvey of a representative sample of patients after topicala) capsaicin 8% therapyb) lidocaine 5% therapyc) botulinum toxin A injectionDRKS00011877
Capsaicin Effect on Cytokines Profile in DyslipidemiaEffect of Administration of Capsaicin on Inflammatory Cytokines Profile(TNFa , IL - 1ß , IL - 6, IL -8 , MIP - 1ß) in Individuals With Dyslipidemia.NCT02823912
Arbitrary versus reflex cough force in capsaicin inhalation : A Comparison between persons without neurogenic dysphagia and persons with neurogenic dysphagiaArbitrary versus reflex cough force in capsaicin inhalation : A Comparison between persons without neurogenic dysphagia and persons with neurogenic dysphagiaDRKS00010719
Acute effects of capsaicin.Acute effects of capsaicin on energy expenditure, fat oxidation and satiety in negative energy balance.NL-OMON29649
A Mechanistic Evaluation of the Nociceptive Desensitizing Properties of Topical CapsaicinEn undersøgelse af Mekanismerne Bag Nociceptiv Desensibilisering forårsaget af Topikal CapsaicinNCT03587220
The effect of capsaicin and cinnamaldehyde on intestinal permeability, gallbladder motility and satietyThe effect of capsaicin and cinnamaldehyde on intestinal permeability, gallbladder motility and satiety - Capsaicine protocolNL-OMON34052
The Effect of Capsaicin and Cinnamaldehyde on Intestinal PermeabilityThe Effect of Capsaicin and Cinnamaldehyde on Intestinal Permeability, Gallbladder Motility and SatietyNCT01667523
Desensitization of Nociceptive Afferents by Application of Topical Capsaicin, Trans-cinnamaldehyde and L-mentholTemporal Profile of the Nociceptive Desensitization Induced by 8% Topical Capsaicin and the Functional Independence of Transient Receptor Potential Ankyrin 1 (TPRA1)- and Vanilloid 1 (TRPV1)-Expressing Nociceptive AfferentsNCT03132142
Effect of TABATA and Piperine and Capsaicin on Nitric Oxide and Creatine KinaseComparison of the effect of Piperine and Capsaicin on Nitric Oxide and Creatine Kinase after 8 weeks Tabata bodybuilding execrciseIRCT20171210037809N3
Thermosensitivity of a Topical Palmitated Formulation of CapsaicinA Double-Blind, Randomized, Pilot Study to Investigate the Thermosensitivity of a Topical Palmitated Formulation of CapsaicinNCT05649228
Capsaicin to Prevent Delayed Chemotherapy Induced Nausea and Vomiting (CapCIN)Single-blinded, Randomized Study of Capsaicin to Prevent Delayed Chemotherapy-induced Nausea and VomitingNCT04918069