IMPPAT Phytochemical information: 
Hydroxytyrosol

Hydroxytyrosol
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
Clinical study to investigate lipid modifying effects of hydroxytyrosol – a randomized, double-blind, placebo-controlled parallel studyClinical study to investigate lipid modifying effects of hydroxytyrosol – a randomized, double-blind, placebo-controlled parallel study - BTS1214/18DRKS00015251
Olive Oil and Cardiovascular HealthEffects of Hydroxytyrosol on Vascular HealthNCT01983943
Human Study of Hydroxytyrosol on Phase II Enzymes in Healthy SubjectsNutritional Intervention Study to Evaluate the Effect of Hydroxytyrosol on Phase II Enzymes in Healthy SubjectsNCT02273622
Effects of hydroxytyrosol on protection of LDL particles from oxidative damage: a randomized, double-blind, placebo-controlled cross-over studyEffects of hydroxytyrosol on protection of LDL particles from oxidative damage: a randomized, double-blind, placebo-controlled cross-over study - BTS964_16DRKS00010859
Punicalagin and Hydroxytyrosol Mixture on Different Inflammatory MarkersEffects of Punicalagin and Hydroxytyrosol Mixture on Different Inflammatory Markers Related With Cardiovascular Disease: a Crossover Study in Healthy Middle-aged VolunteersNCT02042742
Effects of olive oil treatments for facial dark spotsClinical efficacy of oral and topical treatments based on olive oil extract titrated in hydroxytyrosol to melasma controlRBR-2mg3xw
Relevance of the Ethanol Dose in the Generation of Endogenous HydroxytyrosolHydroxytyrosol as an Endogenous and Natural Antioxidant: Modulation by Alcohol Intake. Substudy 1. Evaluating the Relevance of the Ethanol Dose in the Generation of Endogenous Hydroxytyrosol (DOPET).NCT01788670
Clinical Study of Hydroxytyrosol (HT) in Mitochondrial DiseasesOpen Label Pilot Study Using Hydroxytyrosol (HT) as a Dietary Supplement in Patients With Mitochondrial Diseases (MDs)NCT04543968
Bioavailability of Hydroxytyrosol From Olive Watery Extract SupplementsBioavailability of Hydroxytyrosol From Two Olive Watery Extract Supplements and Their Effects on Lipid PeroxidationNCT04876261
Positive Effects of Daily Consumption of Bread Enriched With Hydroxytyrosol on the Results of a 12-week Dietary Intervention on Subjects With Type 2 Diabetes Mellitus and Overweight/ ObesityPositive Effects of Daily Consumption of Bread Enriched With Hydroxytyrosol on the Results of a 12-week Dietary Intervention on Subjects With Type 2 Diabetes Mellitus and Overweight/ ObesityNCT04899791
Evaluation of the effect of polyphenol (hydroxytyrosol) intake on cognitive function in middle-aged and elderly peopleEvaluation of the effect of polyphenol (hydroxytyrosol) intake on cognitive function in middle-aged and elderly people - Evaluation of the effect of hydroxytyrosol intake on cognitive functionJPRN-UMIN000050239
Hydroxytyrosol Dietary Supplement and Prevention of Age-Related DiseasesHealth Effects of Chronic Supplementation with a Natural Extract High in Hydroxytyrosol in Individuals At High Risk of Developing Age-related DiseasesNCT06295913
Bioavailability of Hydroxytyrosol in Humans Co-administered With EPAHydroxytyrosol Bioavailability in Humans: A Comparative Study of Three EPA-Enriched FormulationsNCT06735222
Phase I Trial of 5-Fluorouracil (5FU) -Based Therapy in Combination With Hydroxytyrosol (HT) in Patients With Advanced or Metastatic Colorectal CancerPhase I Trial of 5-Fluorouracil (5FU) -Based Therapy in Combination With Hydroxytyrosol (HT) in Patients With Advanced or Metastatic Colorectal CancerNCT06833866
Effects on Cardiovascular Risk Factors of the Endogenous Hydroxytyrosol Generation After the Combined Intake of Wine and Tyrosol in HumansA Single-center, Crossover, Randomized and Controlled Nutritional Intervention Clinical Trial. A Nutritional Intervention StudyNCT02783989
Effects of Hydroxytyrosol Administration in Anthropometric Parameters in Overweight and Obese WomenEvaluation of the Effects of the Administration of 5 Milligrams and 15 Milligrams of Hydroxytyrosol, an Extra Virgin Olive Oil Phenolic Compound, Versus Placebo, Combined With Diet, in Anthropometric Parameters in Overweight and Obese WomenNCT04317079
Contribution of Wine Components on Hydroxytyrosol Body Concentrations and Biological EffectsHydroxytyrosol as an Endogenous and Natural Antioxidant: Modulation by Alcohol Intake. Substudy 2. To Establish the Contribution of Wine Components on Hydroxytyrosol Body Concentrations and Biological EffectsNCT01790672
Hydroxytyrosol and Vitamin E in Pediatric NASHHydroxytyrosol and Vitamin E in the Treatment of Children With Biopsy-proven NASHNCT02842567