| Prevention of diabetes with a novel butyrate-enriched triglyceride | Prevention of diabetes with a novel butyrate-enriched triglyceride - Preventing Diabetes with Butyrate-Triglyceride | NL-OMON56880 |
| Butyrate-enriched Triglyceride and Diabetes Prevention | Prevention of Diabetes with a Novel Butyrate-enriched Triglyceride | NCT06384313 |
| Butyrate/Hexanoate in Metabolic Health | Butyrate/Hexanoate-enriched Triglycerides for Metabolic Health | NCT04662411 |
| Clinical study on Potatodaat® in Healthy individuals | Evaluation of efficacy and safety of a proprietary high resistance Potato starch- Potatodaat® as a prebiotic by SCFA analysis (Short Chain Fatty Acids- Butyrate, Acetate and Propionate) and Gut Microbiota in Healthy individuals â?? A Double blind, Randomized, Active controlled, Multicenter, Comparative, Interventional, Prospective, Clinical study | CTRI/2022/12/048064 |
| Butyrate/hexanoate-enriched triglycerides for metabolic health | Butyrate/hexanoate-enriched triglycerides for metabolic health - Butyrate/hexanoate in metabolic health | NL-OMON49589 |
| Ganciclovir Plus Arginine Butyrate in Treating Patients With Cancer or Lymphoproliferative Disorders Associated With the Epstein Barr Virus | A PHASE I TRIAL OF BUTYRATE AND GANCICLOVIR IN EBV-ASSOCIATED MALIGNANCIES | NCT00006340 |
| Evaluation of Butyrate Effect on Diarrhea | Evaluation of Butyrate, Zinc and Vitamine D Effect on Microbiota Modulation and Prevention of Antibiotic-associated Diarrhea | NCT06982703 |
| ?Effect of butyrate in ulcerative colitis | Evaluation the effect of postbiotic butyrate supplementation on the expression of circadian genes, inflammation, sleep quality and psychological factors in patients with ulcerative colitis | IRCT20211214053401N1 |
| Leaking of bacterial products from the intestine into the circulation can cause inflammation of the joints of the hand. We presume that preparations of slow release calcium butyrate can stop this leakage. This will result in less inflammation and in less pain. | Role of the intestine on osteoarthritis of the hand and the effect of Sustained Release Calcium Butyrate. - Intestine and osteoarthritis | EUCTR2020-001071-33-NL |
| Interaction between intestine and osteoarthritis of the hand and the effect of Sustained Release Calcium Butyrate | Interaction between intestine and osteoarthritis of the hand and the effect of Sustained Release Calcium Butyrate - Intestine, microbiome and osteoarthritis | NL-OMON55339 |
| Clinical observation of fluticasone propionate cream 0.05% wet package therapy versus hydrocortisone butyrate cream wet package therapy in the treatment of moderate to severe AD in children | Clinical observation of fluticasone propionate cream 0.05% wet package therapy versus hydrocortisone butyrate cream wet package therapy in the treatment of moderate to severe AD in children | ChiCTR2100053251 |
| Efficacy and safety of clevidipine butyrate injection in the treatment of hypertensive emergency and sub-emergency: a randomized, single-blind, positive drug parallel controlled, multi-center clinical study | Efficacy and safety of clevidipine butyrate injection in the treatment of hypertensive emergency and sub-emergency: a randomized, single-blind, positive drug parallel controlled, multi-center clinical study | ChiCTR2100050577 |
| The Efficacy of Sodium Butyrate and Probiotics in Patients With Irritable Bowel Syndrome | An Assessment of the Efficacy of Microencapsulated Sodium Butyrate and a Probiotic Mixture in Patients With Irritable Bowel Syndrome - a Randomized Double-blind Placebo-controlled Study | NCT05013060 |
| The Effects of sodium butyrate supplementation on obesity | The Effects of butyrate supplementation on plasma atherogenic index(AIP), serum level of hsCRP, expression level of adiponectin receptors(AdipoR1& R2), AMP activated protein kinase(AMPK) and uncoupling proteins(UCP2&3) genes in Obese individuals on a weight loss diet: A Randomized, Triple- Blind, Placebo- Controlled Clinical Trial | IRCT20190303042905N3 |
| The Use of Butyrate Therapy in Pediatric Ulcerative Colitis | Butyrate Therapy in Hispanic Children With Ulcerative Colitis | NCT05218850 |
| Analysis of Microbiota Changes Induced by Microencapsulated Sodium Butyrate in Patients With Inflammatory Bowel Disease | Inflammation and Intestinal Microbiota Modulation in Inflammatory Bowel Diseases | NCT04879914 |
| Mode of Action of Butyrate in the Human Colon | Mode of Action of Butyrate in the Human Colon | NCT05249023 |
| Food Allergy treatment with Butyrate (FAB) | Monocentric, randomised single-blind, placebo-controlled clinical study to assess whether a Multicentric, randomised clinical pilot-study to assess whether a diet rich in milk products could increase oral tolerance to the incriminated food protein in food allergy children | ISRCTN16288291 |
| Effects of a butyrate enema on systemic concentrations of short chain fatty acids | Effects of a butyrate enema on systemic concentrations of short chain fatty acids - Effects of butyrate enema on systemic SCFA concentrations | NL-OMON32250 |
| Effects of Butyrate on Affective Processes | Effects of Butyrate on Affective Processes | NCT04722549 |
| Pharmacokinetics study of Lovidipine butyrate emulsion for injection in Healthy Chinese Volunteers | Pharmacokinetics study of Lovidipine butyrate emulsion for injection in Healthy Chinese Volunteers | ChiCTR2100042280 |
| Effects of Butyrate Against Pediatric Obesity | Effects of Oral Supplementation of Butyrate in Children With Obesity | NCT04620057 |
| Butyrate: Effect of Oral Administration in patients with Mild Hypertension | Butyrate: Effect of Oral Administration in patients with Mild Hypertension | NL-OMON22936 |
| Intestine, microbiome and osteoarthritis | Role of the intestine on osteoarthritis of the hand and the effect of Sustained Release Calcium Butyrate (SRCaBu) | NL-OMON28862 |
| Effect of adding sodium butyrate to BCG on bodys immune system and urinary bladder microorganisms in patients with urinary bladder cancer | Supplementary Intravesical Sodium Butyrate to Intravesical Bacillus Calmette-Guérin in Non Muscle Invasive Bladder Cancer: A Study on the Tumour Immuno-microenvironment and A Meta-transcriptomic and Microbiome analysis. | CTRI/2022/02/040207 |
| Butyrate supplements improve efficacy in patients with moderate to severe chronic spontaneous urticaria, A randomized, double-blind, placebo-controlled trial | Butyrate supplements improve efficacy in patients with moderate to severe chronic spontaneous urticaria, A randomized, double-blind, placebo-controlled trial | TCTR20220302003 |
| Ca-Mg Butyrate in GWI | Microbiome Targeted Oral Butyrate Therapy in Gulf War Multisymptom Illness | NCT05367245 |
| The regulatory effect of sodium butyrate supplementation on immune cells in patients with type 1 diabetes. | Effects of sodium butyrate on immune cells in patients with type 1 diabetes: a randomized, controlled, triple-blind clinical study | ChiCTR2500100916 |
| Effects of the Short-Chain Fatty Acids-Targeted Dietary Interventions on the Selected Autonomic Functions in Humans | Effects of the Resistant Starch and Sodium Butyrate Supplementation on the Respiratory and Cardiovascular Autonomic Control in Humans | NCT06851039 |
| Efficacy of sodium butyrate in inducing remission in patients with mild-to-moderate ulcerative colitis | Efficacy of microencapsulated sodium butyrate as an add-on therapy in inducing remission in patients with mild-to-moderate ulcerative colitis: Results from a multi-center, double-blind, randomized, placebo-controlled study | ISRCTN14915997 |
| The effect of sodium butyrate on abdominal symptoms and carbohydrate metabolism in patients with type 2 diabetes | The effect of microencapsulated sodium butyrate on abdominal symptoms and carbohydrate metabolism in patients with type 2 diabetes: a randomized placebo-controlled trial | ISRCTN10844715 |
| A Pharmacokinetic Comparison of Three Butyrate Products | A Pharmacokinetic Comparison of Three Butyrate Products | NCT06700785 |
| The NaBu Effect on Menstruation in Women | The Effect of Sodium Butyrate on Menstrual Symptoms in Women | NCT06653426 |
| Butyrate Supplementation in Children With Autism Spectrum Disorder (ASD) and Functional Gastrointestinal Disorders | Effects of a Postbiotic Supplementation on Gastrointestinal and Core Symptoms in Autism Spectrum Disorder: A Multicenter Randomized Controlled Trial | NCT06514573 |
| Effectiveness of a Butyrate Formulation and Butyrate + Polyphenol Formulation on Gut Health, Permeability and Associated Symptoms | A Double-blind, Randomized, Placebo-controlled Study to Evaluate the Effects of a Butyrate Formulation and a Butyrate + Polyphenol Formulation on Gut Health, Permeability and Associated Symptoms | NCT06419231 |
| Dietary Supplementation With Butyrate in Individuals With Liver Steatosis and Metabolic Syndrome | Dietary Supplementation With Butyrate in Individuals With Liver Steatosis and Metabolic Syndrome: a Randomized Double-blind Placebo-controlled Clinical Trial | NCT06398522 |
| Effects of an Encapsulated Calcium Butyrate Dietary Supplement on Gut Health | A Single-Arm, Pilot Study to Assess the Effects of an Encapsulated Calcium Butyrate Dietary Supplement on Gut Health | NCT06397482 |
| Investigating Sodium Butyrate as Treatment for Anorexia Nervosa | Evaluating the Effectiveness of Sodium Butyrate for Treatment of Anorexia Nervosa in Individuals Aged 16 and Over - An Open-Label Proof of Concept Study | ACTRN12624000368538 |
| Investigating the effect of Butyrate on inflammatory genes and apoptosis in Ulcerative colitis | Effect of Butyrate on anti inflammatory genes Sirt1 and Pgc1alpha and apoptosis gene Bax and Bcl2 in Ulcerative colitis patients | IRCT20221215056828N1 |
| Chronic Mesenteric Ischemia Breath Testing | Heavy Isotope-labeled-butyrate and Glucose in Breath Testing to Detect Mesenteric Ischemia, a Proof-of-concept Study in Healthy Volunteers. | NCT06022588 |
| A Study of Clevidipine Butyrate Injectable Emulsion in the Treatment of Hypertensive Emergency and Sub-emergency | A Randomized, Double-blind, Active-compared Phase ? Clinical Trial to Evaluate Clevidipine Butyrate Injectable Emulsion in the Treatment of Hypertensive Emergency and Sub-emergency | NCT05783557 |
| Effect of Butyrate Supplement on Rheumatoid Arthritis | A Pilot Study to Evaluate Efficacy and Safety of Butyrate Supplement in the Treatment of Rheumatoid Arthritis | NCT05576597 |
| Phase III clinical trial protocol of clevidipine butyrate injection emulsion in the treatment of hypertensive emergencies and sub-acute emergencies (multicenter, randomized, double-blind, parallel, active controlled trial) | Phase III clinical trial protocol of clevidipine butyrate injection emulsion in the treatment of hypertensive emergencies and sub-acute emergencies (multicenter, randomized, double-blind, parallel, active controlled trial) | ChiCTR2200063062 |
| A clinical trial to study the effects of two drugs, Tofacitinib 2% w/w ointment and 0.1% hydrocortisone butyrate ointment in patients suffering from dermatitis. | A randomized, parallel-group, multi-center, active-controlled, Comparative, Phase-III study to evaluate efficacy and safety of Tofacitinib Ointment 2% w/w in subjects with mild-to-moderate Atopic Dermatitis. | CTRI/2022/07/043740 |
| Butyrate: effect of oral administration in patients with mild hypertension | Butyrate: effect of oral administration in patients with mild hypertension - BEAM study | NL-OMON49499 |
| Gut Butyrate and Blood Pressure in African Americans | Effect of Gut Butyrate Delivery on Blood Pressure in African Americans With Hypertension | NCT04415333 |
| Effect of butyrate in obesity | The Effects of butyrate supplementation on the expression levels of PGC-1a, PPARa and UCP1 genes, serum level of GLP-1, metabolic parameters, and anthropometric indices in obese individuals on a weight loss diet: A Triple- Blind, Randomized, Placebo- Controlled Clinical Trial. | IRCT20190303042905N2 |
| Labelled-butyrate and labelled-glucose breath testing to detect mesenteric ischemia, a proof of principle study in healthy volunteers | Labelled-butyrate and labelled-glucose breath testing to detect mesenteric ischemia, a proof of principle study in healthy volunteers - CMI breath test | NL-OMON50079 |
| Effect of a Butyrate Enema on the Systemic Concentration of Short Chain Fatty Acids | Effect of a Butyrate Enema on the Systemic Concentration of Short Chain Fatty Acids | NCT02271802 |
| Effects of butyrAte comPared to donor faeces transPlantation on mETabolIsm and saTiEty in patients with metabolic syndrome | Effects of butyrAte comPared to donor faeces transPlantation on mETabolIsm and saTiEty in patients with metabolic syndrome | NL-OMON26960 |
| Effects of infant formula enriched with butyrate on immune and intestinal functions | administration of a formula enriched with butyrate in healthy newborns to assess an improvement in intestinal and immune functions | ACTRN12614000533695 |
| Effects of butyrate compared to donor faeces transplantation on metabolism and satiety in patients with metabolic syndrome | Effects of butyrate compared to donor faeces transplantation on metabolism and satiety in patients with metabolic syndrome - APPETITE study | NL-OMON41779 |
| Study to Determine the Effect of Synbiotics in Patients With Pre-diabetes | Placebo Controlled Pilot Trial to Determine the Effect of Metabolic Rheostat™ and Butyrate Ultra on Hemoglobin A1C and Blood Glucose Levels in Patients With Pre-diabetes | NCT04428606 |
| Butyrate as therapy for congenital chloride diarrhea | Effects of oral butyrate therapy on children with congenital chloride diarrhea | ACTRN12613000450718 |
| Randomised, Double-blind, Placebo-controlled Study of Topical Clobetasone Butyrate 0.05% Cream in Subjects With Eczema for Two Weeks to Evaluate the Efficacy and Safety | Randomised, Double-blind, Placebo-controlled Study of Topical Clobetasone Butyrate Cream in Patients With Eczema for Two Weeks to Evaluate the Efficacy and Safety | NCT01567995 |
| Effects of Recto-colic Enemas of Butyrate on the Digestive Disorders of Very Low Birth Weight Preterms <1250 Grams | Effects of Recto-colic Enemas of Butyrate on the Digestive Disorders of Very Low Birth Weight Preterms <1250 Grams. Clinical Trial Prospective, Monocentric, Randomized in Double-blinded. | NCT01536483 |
| The effect of proactive therapy with tacrolimus and betamethasone butyrate on atopic dermatitis: Randomized placebo-controlled study | The effect of proactive therapy with tacrolimus and betamethasone butyrate on atopic dermatitis: Randomized placebo-controlled study - The effect of proactive therapy on atopic dermatitis: Randomized placebo-controlled study | JPRN-UMIN000006955 |
| STUDIE ZUR MESSUNG DER VAGINALEN INTERLEUKINE BEI PATIENTINNEN MIT ZERVIKALEN NEOPLASIEN (CIN 1-3) ODER CHRONISCHER CANDIDIASIS VAGINALIS UNTER BEHANDLUNG MIT 4PHENYL-BUTYRATE | STUDIE ZUR MESSUNG DER VAGINALEN INTERLEUKINE BEI PATIENTINNEN MIT ZERVIKALEN NEOPLASIEN (CIN 1-3) ODER CHRONISCHER CANDIDIASIS VAGINALIS UNTER BEHANDLUNG MIT 4PHENYL-BUTYRATE | EUCTR2010-021502-38-DE |
| A PILOT STUDY TO INVESTIGATE THE SAFETY, TOLERABILITY AND EFFICACY OF A DAILY DOSE OF 500MG. LU901 (4PHENYL-BUTYRATE, CONTROLLED RELEASE TABLETS) IN ADDITION TO STANDARD HORMONAL TREATMENT IN PATIENTS WITH METASTASIZED PROSTATE CARCINOMA AND A LIFE EXPECTANCY OF AT LEAST 6 MONTHS. | A PILOT STUDY TO INVESTIGATE THE SAFETY, TOLERABILITY AND EFFICACY OF A DAILY DOSE OF 500MG. LU901 (4PHENYL-BUTYRATE, CONTROLLED RELEASE TABLETS) IN ADDITION TO STANDARD HORMONAL TREATMENT IN PATIENTS WITH METASTASIZED PROSTATE CARCINOMA AND A LIFE EXPECTANCY OF AT LEAST 6 MONTHS. | EUCTR2010-020681-16-DE |
| Study of Arginine Butyrate and Ganciclovir/Valganciclovir in EBV(+) Lymphoid Malignancies | A Phase II Trial of Low-Dose Arginine Butyrate and Ganciclovir/Valganciclovir in EBV(+)Lymphoid Malignancies | NCT00917826 |
| The Effects of Butyrate Enemas on Visceral Perception | The Effects of Butyrate Enemas on Visceral Perception | NCT00726817 |
| Effects of Butyrate on Colonic Health of Patients With Diarrhoea Predominant IBS and UC in Remission | Effects of Butyrate on Colonic Health of Patients With Diarrhoea Predominant | NCT00696098 |
| Adherence to Topical Hydrocortisone 17-butyrate 0.1% (Locoid®) Using Different Vehicles in Adults With Atopic Dermatitis | Adherence to Topical Hydrocortisone 17-butyrate 0.1% (Locoid®) Using Different Vehicles in Adults With Atopic Dermatitis | NCT00693693 |
| Effects of Butyrate Enemas on Colonic Health | Effects of Butyrate Enemas on Colonic Health | NCT00693355 |
| Clinical Evaluation of T.R.U.E. TEST® Panel 3.2 Allergens: Gold Sodium Thiosulfate, Hydrocortisone-17-butyrate, Methyldibromoglutaronitrile, Bacitracin, Parthenolide, Disperse Blue 106, and Bronopol - Safety and Efficacy Trial | Clinical Evaluation of T.R.U.E. TEST® Panel 3.2 Allergens: Gold Sodium Thiosulfate, Hydrocortisone-17-butyrate, Methyldibromoglutaronitrile, Bacitracin, Parthenolide, Disperse Blue 106, and Bronopol - Safety and Efficacy Trial | EUCTR2008-000168-18-DK |
| oral Butyrate Use in TYpe 1 diabetes: Effects on Regulation of bActerial translocation, T-cell and innate immune system function and Endotoxemia | oral Butyrate Use in TYpe 1 diabetes: Effects on Regulation of bActerial translocation, T-cell and innate immune system function and Endotoxemia | NL-OMON26759 |
| RCT to Describe the Effects of Colon Delivered Acetate, Propionate and Butyrate on Satiety and Glucose Homeostasis | | NCT02451189 |
| The effect of Oral BUtyrate on human Glucose and brownfAT metabolism | The effect of Oral BUtyrate on human Glucose and brownfAT metabolism - OBUGAT study | NL-OMON38772 |
| Sodium Butyrate For Improving Cognitive Function In Schizophrenia | Sodium Butyrate As A Treatment For Improving Cognitive Function In Schizophrenia | NCT02654405 |
| Hydroxocobalamin Approach for Reducing of Calprotectin With Butyrate for Ulcerative Colitis Remission | Hydroxocobalamin Approach for Reducing of Calprotectin With Butyrate for Ulcerative | NCT04259060 |
| Effect of Butyrate on Inflammation and Albuminuria in Patients With Albuminuria, Type 1 Diabetes and Intestinal Inflammation | The Butyful Study. Effect of Butyrate on Inflammation and Albuminuria in Patients With Albuminuria, Type 1 Diabetes and Intestinal Inflammation A Randomized, Double-blind, Placebo-controlled Study | NCT04073927 |
| Pivotal in vivo bioequivalence study of comparing Eumovate cream to clobetasone butyrate cream applied to the skin in healthy male and female volunteers. | A pivotal in vivo bioequivalence study comparing Eumovate cream to Clobetasone butyrate cream, using the appropriate dose duration (ED50) for Eumovate cream calculated from the Pilot dose duration-response study, using healthy male and female volunteers who meet the responder and detector criteria. | ACTRN12615000815561 |
| Effects of Butyrate Enemas on Postoperative Intestinal Mobility Disorders in Hirschsprung's Disease | Effects of Butyrate Enemas on Postoperative Intestinal Mobility Disorders in Hirschsprung's | NCT03660176 |
| Dietary Interventions and Butyrate Production in Behçet's Patients | Therapeutic Modulation of Butyrate Production in Behçet's Patients: a Dietary Intervention Trial | NCT03274648 |
| Sodium Butyrate For Improving Cognitive Function In Schizophrenia | Sodium Butyrate As A Treatment For Improving Cognitive Function In Schizophrenia | NCT03010865 |
| Effect of sodium butyrate in prevention and treatment of type 2 diabetes | The effect of sodium butyrate supplementation on serum oxidative stress indices and gene expression level of pyroptosis related inflammatory factors in type 2 diabetic patients: A randomized, double-blind, placebo-controlled trial | IRCT20090609002017N33 |
| Phase II Randomized Trial:Arginine Butyrate Plus Standard Local Therapy in Patients With Refractory Sickle Cell Ulcers | Phase II Trial of Arginine Butyrate for Treatment of Refractory Leg Ulcers in Sickle Cell Disease or Beta Thalassemia | NCT00004412 |
| Phase II Study of Arginine Butyrate With or Without Epoetin Alfa in Patients With Thalassemia Intermedia | | NCT00006136 |
| Study into the safety and efficacy of eczema cream Clobetasone Butyrate. | Multi-center, Randomised, Double-blind, Parallel, Placebo Controlled Study Of 0.05% Clobetasone Butyrate Cream in Subjects with Eczema to evaluate the Efficacy and Safety. | EUCTR2015-004899-30-Outside-EU/EEA |
| The effect of sodium butyrate and inulin supplementation solo and simultaneously on glycemic index, Txnip gene expression and circulating levels of GLP-1, miR-204, miR-200c and miR-21 in patients with type 2 diabetes | The effect of sodium butyrate and inulin supplementation solo and simultaneously on glycemic index, Txnip gene expression and circulating levels of GLP-1, miR-204, miR-200c and miR-21 in patients with type 2 diabetes | IRCT201605262017N29 |
| *Effects of Butyrate on Intestinal permeability & inflammation, Intellectual performance, Immune activation and systemic Inflammation in renal disease. | *Effects of Butyrate on Intestinal permeability & inflammation, Intellectual performance, Immune activation and systemic Inflammation in renal disease. - B4I-study | NL-OMON43237 |
| The Effects of Butyrate on Children With Obesity | Effects of Butyrate on Insulin Resistance in Children Affected by Obesity | NCT02721953 |
