IMPPAT Phytochemical information: 
Inosine

Inosine
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
Safety of Urate Elevation in Parkinson's DiseaseA Randomized, Double-blind, Placebo-controlled, Dose-ranging Trial of Oral Inosine to Assess Safety and Ability to Elevate Urate in Early Parkinson's DiseaseNCT00833690
An open-label, single-centered, non-randomized trial of inosine to assess its safety for patients with Parkinson's diseaseAn open-label, single-centered, non-randomized trial of inosine to assess its safety for patients with Parkinson's disease - An evaluation of the safety of inosine for patients with Parkinson's diseaseJPRN-UMIN000009062
A Pilot Study of Inosine in Amyotrophic Lateral Sclerosis (ALS)A Pilot Study of Inosine in Amyotrophic Lateral Sclerosis (ALS)NCT02288091
A Food-Drug Interaction Study of Serum Urate After Oral InosineA Phase 1, Open-label, Randomized, Two-period, Two-treatment, Crossover Study to Evaluate the Effects of Food on the Pharmacokinetics of Urate After a Single Dose of Inosine in Healthy Male SubjectsNCT02614469
The influence of genetic variants on inosine-induced hyperuricaemiaThe influence of genetic variants on inosine-induced hyperuricaemia in healthy adult volunteersACTRN12615001302549
Study of Urate Elevation in Parkinson's Disease, Phase 3A Randomized, Double-blind, Placebo-controlled Trial of Urate-elevating Inosine Treatment to Slow Clinical Decline in Early Parkinson's DiseaseNCT02642393
Multi-centered, placebo-controlled, double-blind, randomized clinical trial to assess the effect of oral inosine on the onset of wearing off in patients with early stage Parkinson's diseaseMulti-centered, placebo-controlled, double-blind, randomized clinical trial to assess the effect of oral inosine on the onset of wearing off in patients with early stage Parkinson's disease - Randomized clinical trial to assess the disease modifying effect of oral inosine for patients with Parkinson's diseaseJPRN-UMIN000020527
Study on efficacy and safety of combination treatment with febuxostat and inosine for patients with heart failureStudy on efficacy and safety of combination treatment with febuxostat and inosine for patients with heart failure - Effect of febuxostat and inosine on heart failureJPRN-UMIN000025427
Clinical study to examine the changes of purine compounds by the simultaneous administration of xanthine oxidase/xanthine dehydrogenase inhibitors and inosine in healthy subjects.Clinical study to examine the changes of purine compounds by the simultaneous administration of xanthine oxidase/xanthine dehydrogenase inhibitors and inosine in healthy subjects. - Study of XO/XDH inhibitors and inosine in healthy subjectsJPRN-UMIN000024027
Studies of efficacy and safety of simultaneous administration of febuxostat and inosine for patients with genetic anemia, and changes of blood and urine purine compoundsStudies of efficacy and safety of simultaneous administration of febuxostat and inosine for patients with genetic anemia, and changes of blood and urine purine compounds - Effect of febuxostat and inosine on anemiaJPRN-UMIN000024750
Studies of efficacy and safety of the combined use of febuxostat and inosine for patients with Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis or multiple sclerosis, and changes of blood and urine purine compounds.Studies of efficacy and safety of the combined use of febuxostat and inosine for patients with Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis or multiple sclerosis, and changes of blood and urine purine compounds. - Effect of febuxostat and inosine on CNS diseasesJPRN-UMIN000024312
Inosine Reverse Chemo Resistance in Triple Negative Breast Cancera Pilot Study to Explore the Efficacy of Inosine Reversing Chemo Resistance in Triple Negative Breast CancerNCT06355024
Effects of Inosine Supplements on Markers of Bone HealthEffects of oral inosine supplements on bone turnover markers in healthy post-menopausal womenACTRN12617000940370
Inosine 5'-Monophosphate to Raise of Serum Uric Acid Level in Patients With Multiple System Atrophy: a Multi-center, Randomized Controlled, Double Blind, Parallel Assigned Clinical TrialInosine 5'-Monophosphate to Raise of Serum Uric Acid Level in Patients With Multiple System Atrophy: a Multi-center, Randomized Controlled, Double Blind, Parallel Assigned Clinical Trial (IMPROVE MSA Study)NCT03403309
Efficacy and safety of antidepressant combined with inosine for depressive disorders in children, adolescents and adults: a randomised, double-blind, placebo-controlled trialEfficacy and safety of antidepressant combined with inosine for depressive disorders in children, adolescents and adults: a randomised, double-blind, placebo-controlled trialChiCTR1800014637
Study on efficacy and safety as well as on the changes in blood purine compounds by the treatment of patients with amyotrophic lateral sclerosis with febuxostat and inosine in combination.Study on efficacy and safety as well as on the changes in blood purine compounds by the treatment of patients with amyotrophic lateral sclerosis with febuxostat and inosine in combination. - Effect of febuxostat and inosine on amyotrophic lateral sclerosisJPRN-UMIN000029308
Study on efficacy and safety of the simultaneous treatment with febuxostat and inosine of patients with Parkinson's disease.Study on efficacy and safety of the simultaneous treatment with febuxostat and inosine of patients with Parkinson's disease. - Effect of febuxostat and inosine on Parkinson's diseaseJPRN-UMIN000030930
Randomized clinical trial to assess the disease modifying effect of oral inosine for patients with Parkinson's diseaseMulti-centered, placebo-controlled, double-blind, randomized clinical trial to assess the effect of oral inosine on the onset of wearing off in patients with early stage Parkinson's disease - Multi-centered, placebo-controlled, double-blind, randomized clinical trial to assess the effect of oral inosine on the onset of wearing off in patients with early stage Parkinson's diseaseJPRN-jRCTs061180060
PK & PD of coadministration of XOR inhibitor and inosinePharmacokinetics and pharmacodynamics study of coadministration of either allopurinol or febuxostat and inosineJPRN-jRCTs031190115
Inosine Energy Expenditure StudyRandomized Cross-over Trial to Investigate the Effect of Inosine on Human Energy ExpenditureNCT04476238
A clinical study to understand the effect of Inosine Pranobex in Covid-19 patients when used along with the standard of Care in Covid patients.An Open-Label, Prospective, Randomized, Comparative, Parallel Group, Multi-Center, Proof of Concept Study to Assess the Efficacy and Safety of Inosine Pranobex Added to Current Standard of Care (CSC) in COVID-19 Patients.CTRI/2020/08/027162
A clinical study to understand the effect of Inosine Pranobex in Covid-19 patients when used along with the defined standard of Care in Covid patientsA Phase 3, Double-Blind, Placebo-Controlled, Prospective, Randomized, Comparative, Parallel Group, Multi-Centre, Study to Assess the Efficacy and Safety of Inosine Pranobex Added to a Defined Standard of Care in Covid-19 Patients.CTRI/2021/02/030892
Serum uric acid change after oral inosine administrationSerum uric acid change after oral inosine administrationChiCTR2200061080
Studies of efficacy and safety of the combined use of febuxostat and inosine for patients with glucose intolerance, and changes of blood and urine purine compounds.Studies of efficacy and safety of the combined use of febuxostat and inosine for patients with glucose intolerance, and changes of blood and urine purine compounds. - Effect of febuxostat and inosine on glucose intoleranceJPRN-UMIN000024316
Treatment of Multiple Sclerosis Using Over the Counter InosineTreatment of Multiple Sclerosis Using Over the Counter InosineNCT00067327
To Assess the Safety, Tolerability and Efficacy of Inosine Pranobex Tablets in Patients with Influenza and Other Acute Respiratory Viral Infections.A Phase IV, Prospective, Multi-centre, Open label, Randomized Two-Arm Study to Assess the Safety, Tolerability and Efficacy of Inosine Pranobex 500 and 1000 mg Tablets Manufactured by Themis Medicare Ltd in Patients with Influenza and Other Acute Respiratory Viral Infections. - NILCTRI/2024/12/077666
Development of Human Nasal Challenge Models With Microbial Constituents and Grass PollenDevelopment of Human Nasal Challenge Models With Microbial Constituents and Grass Pollen: Monophosphoryl lipidA, Poly-inosine-cytosine, Poly-inosine-cytosine Stabilised With Poly-L-lysine and Carboxymethylcellulose, Resiquimod, Tuberculin and Timothy Grass PollenNCT02090374