| Study to Evaluate Intra-articular Resiniferatoxin to Treat Moderate to Severe Pain From Knee Osteoarthritis | A Phase 2, Randomized, Active and Placebo-Controlled, Dose Ranging Study to Evaluate the Efficacy and Safety of Intra-articular Resiniferatoxin to Treat Moderate to Severe Pain From Knee Osteoarthritis | NCT04885972 |
| A Phase 3 Study to Evaluate the Efficacy and Safety of Resiniferatoxin for Pain Due to Osteoarthritis of the Knee | A Phase 3 Placebo-controlled Study to Evaluate the Efficacy and Safety of Intra-articular Administration of Resiniferatoxin Versus Placebo for the Treatment of Moderate to Severe Pain Due to Osteoarthritis of the Knee | NCT04044742 |
| Study to Evaluate Resiniferatoxin in Patients With Knee Osteoarthritis Whose Total Knee Replacement Surgery is Delayed | A Phase 3, Randomized, Multi-center, Blinded, Placebo-controlled Study to Evaluate the Efficacy and Safety of Intra-articular Resiniferatoxin Versus Placebo to Manage Pain in Patients With Osteoarthritis of the Knee Whose Total Knee Replacement Surgery is Delayed | NCT04386980 |
| Phase 3 Study to Assess Resiniferatoxin vs Standard of Care for the Treatment of Intractable Cancer Pain | A Multicenter, Randomized, 2-Arm, Phase 3 Study to Assess the Efficacy and Safety of a Single Epidural Administration of Resiniferatoxin Versus Standard of Care (SoC) for the Treatment of Intractable Pain Associated With Cancer | NCT04572776 |
| Lopain (MTX-071 / resiniferatoxin)Study to determine the safety and clinical effects of intra-articular injections of low doses of Lopain (MTX-071) in patients with chronic osteoarthritic knee joint pain | Lopain (MTX-071 / resiniferatoxin)An open label, single dose phase Ib/IIa study to determine the safety and clinical effects of intra-articular injections of low doses of Lopain (MTX-071) in patients with chronic osteoarthritic knee joint pain | EUCTR2017-004049-26-BE |
| Study to Assess Epidural Resiniferatoxin for the Treatment of Intractable Pain Associated With Advanced Cancer | A Multicenter, Phase 2 Study to Assess the Safety and Efficacy of Epidural Resiniferatoxin for the Treatment of Intractable Pain Associated With Advanced Cancer | NCT05067257 |
| Lopain (MTX-071 / resiniferatoxin) Study to investigate the the safety and clinical effects of intra-articular injections of Lopain (MTX-071) in patients with chronic osteoarthritic knee joint pain after a single dose (Part 1) and after repeated dose administration (Part 2) | Lopain (MTX-071 / resiniferatoxin)An open label, dose-escalating phase I/IIa study to determine the safety and clinical effects of intra-articular injections of Lopain (MTX-071) in patients with chronic osteoarthritic knee joint pain after a single dose (Part 1) and after repeated dose administration (Part 2) | EUCTR2015-001981-24-BE |
| Resiniferatoxin for the Management of Refractory Morton s Neuroma Pain | Phase I Open Label Clinical Trial Using Resiniferatoxin, A Non-Opioid Medication, For the Management of Refractory Morton's Neuroma Pain | NCT05695339 |
| The effect of the drug resiniferatoxin on the bladder as a treatment for cases of incontinence previously unresponsive to treatment. | 25-90 year old females with urodynamically proven refractory idiopathic detrusor activity given resiniferatoxin to assess the benefits of resiniferatoxin treatment on frequency volume chart, quality of life, leakage pad tests. | ACTRN12612000598886 |
| Periganglionic Resiniferatoxin for the Treatment of Intractable Pain Due to Cancer-induced Bone Pain | An Open-Label, Phase 1b Safety and Efficacy Trial of Periganglionic Resiniferatoxin for the Treatment of Intractable Pain Due to Cancer-induced Bone Pain | NCT02522611 |
| Resiniferatoxin to Treat Severe Pain Associated With Advanced Cancer | A Phase I Study of the Intrathecal Administration of Resiniferatoxin for Treating Severe Refractory Pain Associated With Advanced Cancer | NCT00804154 |
| Study to Evaluate Safety and MTD of Epidural Resiniferatoxin Injection for Treatment of Intractable Cancer Pain | A Multicenter, Open-Label, Phase 1b Study to Assess the Safety and Define the Maximally Tolerated Dose of Epidural Resiniferatoxin Injection for the Treatment of Intractable Pain Associated With Cancer | NCT03226574 |
| Study of Resiniferatoxin for Knee Pain in Moderate to Severe Osteoarthritis | Phase 1b Double-blind Study to Assess the Safety, Tolerability and Preliminary Efficacy of Intra-articular Administration of Resiniferatoxin Versus Placebo for the Treatment of Pain Due to Moderate to Severe Osteoarthritis of the Knee | NCT03542838 |
