IMPPAT Phytochemical information: 
Benzoate

Benzoate
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
Phase II Study of Sodium Phenylbutyrate, Sodium Benzoate, Sodium Phenylacetate, and Dietary Intervention for Urea Cycle DisordersNCT00004767
Sodium benzoate in chronic schizophrenia – an open label, add-on safety and efficacy studyIn people with treatment resistant schizophrenia, is sodium benzoate a tolerated and acceptable augmentation strategy: a phase Ib/II study.ACTRN12615000460505
Sodium benzoate for treatment of attenuated psychosisSodium benzoate for treatment of attenuated/transient psychosis. A randomized placebo-controlled trialEUCTR2013-000458-23-FI
Study to Determine the Equivalence of Three Products Containing Metronidazole Benzoate.Comparative Randomized, Single Dose, Three-Period Crossover Open-Label Study to Determine the Bioequivalence Of Terix Labs Ltd Metronidazole Benzoate (400 mg Metronidazole Per Sachet Oral Granules (Formula A)) Relative to 500 mg From Sanofi-aventis Flagyl 125 mg/5 ml (125 mg Metronidazole Per 5 ml Suspension (Formula B)) and Zentiva Flagyl™ 400 mg Tablets (400 mg Metronidazole Per Film Coated Tablets (Formula C)) , After an Oral Administration to Healthy Adults Under Fasting ConditionsNCT02146209
The Efficacy of Sodium Benzoate as an Adjunctive Treatment in Early PsychosisThe Efficacy of Sodium Benzoate as an Adjunctive Treatment in Early PsychosisACTRN12615000187549
Study to Determine the Equivalence of Two Products Containing Metronidazole BenzoateComparative Randomized, Single Dose, Two-Way Crossover Open Label Bioequivalence Study of Terix Labs Ltd Metronidazole Benzoate (400 mg Metronidazole Per Sachet Oral Granules) Versus Zentiva Flagyl™ 400 mg Tablets (400 mg Metronidazole Per Film Coated Tablet), After An Oral Administration Of 400 mg to Healthy Adults Under Fasting ConditionsNCT02402283
Efficacy and Safety Study of Ammonul® in Patients With Grade 3 or 4 Hepatic EncephalopathyA Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Two Doses of AMMONUL® (Sodium Phenylacetate and Sodium Benzoate) Injection 10% / 10% in Subjects With Grade 3 or 4 Hepatic EncephalopathyNCT00597909
Two-part Clinical Study to Evaluate the Safety and Efficacy of NaBen® in Adults with Refractory SchizophreniaAn adaptive Phase II/III, Double-Blind, Randomized, Placebo-controlled, Two-Part, Dose-Finding, Multi-center Study of the Safety and Efficacy of NaBen® (sodium benzoate), a D-Amino Acid Oxidase Inhibitor, as an Add-on with Clozapine, for Residual Symptoms of Refractory Schizophrenia in AdultsEUCTR2017-001170-42-PL
An Observational Study of Alogliptin Benzoate in Participants With Diabetes Mellitus Type 2Local, Multicentre, Observational, Non-Interventional Prospective Study of Alogliptin Benzoate in Patients With Diabetes Mellitus Type 2NCT02756832
Investigating the effect of aluminum hydroxide and sodium benzoate polishing powder on plaque and inflammationComparison of the effect of aluminum hydroxide powder and sodium benzoate on stain, plaque and inflammationIRCT20241111063675N1
A Comparison of Nurtec ODT to Maxalt MLT-ODT in Adult ED Patients With Migraine HeadacheA Comparison of Rimegepant Orally Disintegrating Tablet (Nurtec ODT) to Rizatriptan Benzoate Orally Disintegrating Tablet (Maxalt MLT-ODT) in Adult Patients Presenting to the ED With Migraine Headache: Randomized, Double-Blind, Clinical TrialNCT06473597
Neurotransmitters in Treatment Resistant Schizophrenia Patients With add-on Sodium BenzoateFunctional Connectivity and Associated Neuropeptides Variations in Treatment Resistant Schizophrenia Patients: Treatment Efficacy of add-on Sodium BenzoateNCT06340789
Evaluation of NaBen® (sodium benzoate) in treatment of schizophrenia in adultsAn Adaptive, Phase IIb/III, Multi-center, Prospective, Randomized, Double-Blind Placebo-controlled Study of the Safety and Efficacy of NaBen® (sodium benzoate), a D-Amino Acid Oxidase Inhibitor, as an Add-on Treatment for Schizophrenia in Adults - SNR-04EUCTR2017-001169-26-PL
Dose finding clinical trial of sodium benzoate in people with treatment refractory schizophreniaDose finding clinical trial of sodium benzoate in people with treatment refractory schizophreniaACTRN12621000327886
Multi-center, randomized, double-blind, placebo/positive parallel phase III clinical trial to evaluate the efficacy and safety of fugliglitinate benzoate tablets in type 2 diabetes patients who cannot effectively control blood glucose through diet and exerciseMulti-center, randomized, double-blind, placebo/positive parallel phase III clinical trial to evaluate the efficacy and safety of fugliglitinate benzoate tablets in type 2 diabetes patients who cannot effectively control blood glucose through diet and exerciseChiCTR2000034343
Effect of the bitter taste chemical, denatonium benzoate, on metabolic control in healthy adults.Effect of bitter taste chemical, denatonium benzoate, on glycaemia, gastrointestinal hormones, antropyloroduodenal motility and appetite in healthy adults.ACTRN12616000026426
Study of the effect of benzoic acid on glutamic acidEffects of sodium benzoate on glutamate and glutathione levels in patients with treatment-resistant schizophreniaJPRN-jRCTs031200050
Two-part Clinical Study to Evaluate the Safety and Benefits of NaBen® in Adolescents with SchizophreniaAn Adaptive, Phase IIb/III, Double-Blind, Randomized, Placebo- Controlled, Multi-Center Study of the Safety and Efficacy of NaBen® (sodium benzoate), a D-Amino Acid Oxidase Inhibitor, as an Add-on Treatment for Schizophrenia in Adolescents. - SNR-01-NaBenEUCTR2017-001168-39-PL
Efficacy and Safety of Sodium Benzoate in the Management of Hyperammonemia in Infants, Children and Adolescent With Chronic Liver Disease.Efficacy and Safety of Sodium Benzoate in the Management of Hyperammonemia in Infants, Children and Adolescents With Chronic Liver Disese - A Randomised Controlled Trial.NCT04022941
Pharmacokinetics Evaluation of Fotagliptin Benzoate Tablets and Metformin Hydrochloride Tablets in Single-ues and Combination Therapy in Healthy SubjectsFotagliptin Benzoate Tablets and Metformin Hydrochloride Tablets Pharmacokinetics Evaluation in Healthy SubjectsChiCTR1900022104
Sodium Benzoate and/or N-Acetylcysteine Added to TAU in Patients With Early Schizophrenia Spectrum Disorder.A Multicentre 12-week Randomised Double-blind Placebo Controlled Feasibility Trial of Sodium Benzoate and/or N-acetylcysteine Added to TAU in Patients With Early Schizophrenia Spectrum Disorder.NCT03510741
Role of Sodium Benzoate in the decreasing ammonia levels in children with chronic liver diseaseEfficacy and safety of sodium benzoate in the management of hyperammonemia in infants, children and adoloscents with Chronic liver disese - Randomised Controlled TrialCTRI/2017/08/009329
Pharmaco-Scintigraphic Study to Evaluate the Release Profile of Metronidazole Benzoate CapsulesAn Open Label, Single-site Pharmaco-Scintigraphic Phase I - Study in Healthy Subjects to Evaluate the Gastrointestinal Transit and Release Profile of Radio-labelled Metronidazole Benzoate CapsulesNCT02911298
Multi-center, randomized, double-blind, placebo parallel controlled phase III clinical trial for the efficacy and safety of fugliglitinate benzoate tablets in patients with type 2 diabetes who cannot be effectively controlled by metforminMulti-center, randomized, double-blind, placebo parallel controlled phase III clinical trial for the efficacy and safety of fugliglitinate benzoate tablets in patients with type 2 diabetes who cannot be effectively controlled by metforminChiCTR2000033616
Comparative Efficacy of Phenylbutyrate (PBA) vs. Benzoate in Urea Cycle DisordersComparative Efficacy of Phenylbutyrate vs. Benzoate in Urea Cycle DisordersNCT02111200