| A Study to Establish Safety and Maximum Tolerated Dose of IV Trehalose in Healthy Subjects | A Single Center, Single Ascending Dose, Double-Blind, Randomized, Placebo-Controlled Trial to Establish Safety and the Maximum Tolerated Dose of Intravenous Trehalose Solution in Healthy Subjects | NCT02725957 |
| Clinical trial on dry eye patients | Analysis of comparative efficacy of a combination formula for a lubricant (Trehalose with sodium hyaluronate 1mg/mL) in the management of ocular surface conditions | CTRI/2018/01/011121 |
| Investigation the effect of trehalose on cirrhosis | Investigation the effect of trehalose on Child-Pugh score and MELD in a cirrhotic patient | IRCT20181022041407N12 |
| The Effects of 3% Trehalose Ophthalmic Solution on Corneal Epithelial Barrier Function | The Effects of 3% Trehalose Ophthalmic Solution on Corneal Epithelial Barrier Function | NCT06655441 |
| Investigation the effect of trehalose on Rheumatoid Arthritis | Investigation the role of trehalose on symptoms of a patient with Rheumatoid Arthritis | IRCT20181022041407N13 |
| The effect of trehalose on patients with lysosomal storage diseases | Investigation of the effects of trehalose on quality of life status and paraclinical findings of patients with lysosomal storage diseases (Niemann-Pick, and Mucopolysaccharidosis type III/Sanfilippo syndrome) | IRCT20201129049534N10 |
| Controlled, randomized trial of trehalose powder in air-polishing for subgingival debridement during supportive periodontal treatment. | Controlled, randomized trial of trehalose powder in air-polishing for subgingival debridement during supportive periodontal treatment. - Crtotpiafsddspt | DRKS00006296 |
| Trehalose as add-on Therapy in Bipolar Depression | Trehalose as add-on Therapy in Bipolar Depression | NCT02800161 |
| A clinical study to evaluate the effect of Trehalose gel in the tretment of gum diseases | Evaluation of the efficacy of local application of Trehalose gel as an adjunct to scaling and root planing in the management of chronic periodontitis | CTRI/2016/03/006760 |
| Effect of Ingestion of Different Concentrations of Trehalose Beverage Solutions on High-Intensity Intermittent Exercise Performance | Effect of Ingestion of Different Concentrations of Trehalose Beverage Solutions on High-Intensity Intermittent Exercise Performance - Effect of Ingestion of Different Concentrations of Trehalose Beverage Solutions on High-Intensity Intermittent Exercise Performance | JPRN-UMIN000046293 |
| Trehalose and multiple sulfatase deficiency (MSD) | Investigation of the therapeutic effects of Trehalose in a patient witn multiple sulfatase deficiency (MSD) | IRCT20130829014521N17 |
| Effect of trehalose ingestion during prolonged exercise on subsequent maximal exercise performance | Single ingestion of trehalose enhances a prolonged exercise performance by effective use of glucose and lipid in healthy men - Single ingestion of trehalose enhances a prolonged exercise performance by effective use of glucose and lipid in healthy men | JPRN-UMIN000042752 |
| Effects of a single ingestion of trehalose on exercise performance | Effects of a single ingestion of trehalose on exercise performance - Effects of a single ingestion of trehalose on exercise performance | JPRN-UMIN000035391 |
| Study of the effect of topical trehalose on postoperative clinical course after trabeculectomy | Study of the effect of topical trehalose on postoperative clinical course after trabeculectomy - Effect of topical trehalose on the filtering bleb after trabeculectomy | JPRN-UMIN000031482 |
| The effect of trehalose supplementation on stroke patients | The effect of trehalose on 28 and 60 days' all cause mortality and inflammatory and stress oxidative factors in critical ill stroke patients admitted to the intensive care unit (ICU): A double-blind randomized controlled clinical trial | IRCT20201129049534N9 |
| Oral Trehalose Therapy to Reverse Arterial Aging in Middle-Aged and Older Adults | Oral Trehalose Therapy to Reverse Arterial Aging in Middle-Aged and Older Adults | NCT01575288 |
| Beneficial effects of trehalose eye-drops on the postoperative course after anti-glaucomatous trabeculectomy surgery | Effect of trehalose eye-drops on the maintenance of filtration bleb after trabeculectomy - postoperative instillation of trehalose after trabeculectomy | JPRN-jRCTs021180008 |
| Clinical Effects of Oral Trehalose In Patients With Spinocerebellar Ataxia 3 | Clinical Effects of Oral Trehalose In Patients With Spinocerebellar Ataxia 3: A Pilot Study | NCT04426149 |
| Treatment of Oculopharyngeal Muscular Dystrophy With Trehalose | A Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Trial of Trehalose for the Treatment of | NCT04226924 |
| EFFECT OF TREHALOSE SOLUTION SPRAY ON POST-RADIATION XEROSTOMIA | EFFECT OF TREHALOSE SOLUTION SPRAY ON POST-RADIATION XEROSTOMIA RELATED QUALITY OF LIFE IN HEAD AND NECK CANCER PATIENTS | TCTR20190817004 |
| The study for the moisturizing effect by trehalose | The placebo contol study for the increasing effect of the amount of corneum water by trehalose in the normal skin surfaces of the external aspects of the left and right forearms and of the external aspects of the left and right lower legs. - SCWT | JPRN-jRCTs061190022 |
| Trehalose and Alzheimer disease | Evaluation of the therapeutic effects of trehalose in patients with Alzheimer disease | IRCT20130829014521N15 |
| Trehalose and lysosomal storage diseases | Investigation of the therapeutic effects of Trehalose in lysosomal storage diseases (Niemann-Pick types A & B, and Mucopolysaccharidosis type III/Sanfilippo syndrome) | IRCT20130829014521N16 |
| Study to compare the effect of Trehalose over sodium hyaluronate in patients of dry eye disease | A prospective, randomized, interventional and comparative open label trial to compare efficacy ofTrehalose 3% over sodium hyaluronate 0.1% in patients with dry eye disease | CTRI/2020/04/024605 |
| Mycose AdminiStration for HealIng Alzheimer NEuropathy (MASHIANE) | Evaluation of the Therapeutic Effects of Trehalose in Patients With Alzheimer Disease | NCT04663854 |
| The study for the moisturizing effect by trehalose(SMET) | The placebo control study for the increasing effect of the amount of corneum water by trehalose in the normal skin surfaces of the external aspects of the left and right forearms and of the external aspects of the left and right lower legs.(SCWT) | JPRN-jRCTs061200045 |
| Evaluation of the effect of oral trehalose in patients with traumatic head injury in ICU | Evaluation of the effect of oral trehalose on inflammatory factors, oxidative stress and nutritional and clinical status in patients with traumatic head injury receiving enteral nutrition- a pilot study | IRCT20210508051223N1 |
| Investigation the effect of trehalose on ALS | Investigation the effect of trehalose on function of an ALS patient | IRCT20181022041407N6 |
| Study on trehalose activated autophagy system to promote wound healing | Study on trehalose activated autophagy system to promote wound healing | ChiCTR2100049976 |
| A 24-week Open Label, Basket Study of SLS-005 (Trehalose Injection 90.5 mg/mL Intravenous Infusion) in the Treatment of Adults with Neurodegenerative Diseases. | A 24-week Open Label, Basket Study of the safety, tolerability and treatment responses of SLS-005 (Trehalose Injection 90.5 mg/mL Intravenous Infusion) in Adults with Neurodegenerative Diseases | ACTRN12621001755820 |
| Trehalose and aortic inflammation | Investigation of the therapeutic effects of Trehalose in aortic inflammation in patients with cancer | IRCT20130829014521N20 |
| STRIDES - A Clinical Research Study of an Investigational New Drug to Treat Spinocerebellar Ataxia | A DOUBLE-BLIND, RANDOMIZED, PLACEBO CONTROLLED TRIAL TO ASSESS SAFETY AND EFFICACY OF SLS-005 (TREHALOSE INJECTION, 90.5 MG/ML FOR INTRAVENOUS INFUSION) FOR THE TREATMENT OF ADULTS WITH SPINOCEREBELLAR ATAXIA - SLS-005-302 | CTIS2022-501004-10-00 |
| Intermediate-Sized Expanded Access Study | An Expanded Access Protocol of Intravenous Trehalose Injection 90.5 mg/mL Treatment of Patients With Amyotrophic Lateral Sclerosis | NCT05597436 |
| Effect of trehalose in patients with head trauma | The effect of trehalose on inflammatory markers, stress oxidative, clinical symptoms and mortality in patients with head trauma: a randomized double-blind placebo controlled trial | IRCT20121216011763N55 |
| The effect of Trehalose on survival of ICU admitted patients | Evaluation of the effect of Trehalose on survival and severity of disease in patients admitted to the intensive care unit | IRCT20130829014521N22 |
| Investigation of the effects of trehalose on quality of life of patients with lysosomal storage disorders | Investigation of the effects of trehalose on quality of life status and paraclinical findings of patients with lysosomal storage disorders (Niemann-Pick and mucopolysaccharidosis type III (Sanfilippo)) | IRCT20130829014521N23 |
| Simplified Method for Freezing Small Numbers of Human Spermatozoa using Sole Trehalose | Cryopreservation of Single Human Spermatozoa using Sole Trehalose - NIL | CTRI/2024/02/062755 |
| Effect of trehalose on treatment of Ataxia Telangiectasia | The effects of trehalose on the improvement of clinical symptoms in patients with Ataxia Telangiectasia | IRCT20210413050958N8 |
| Investigation the effect of trehalose on PSP | Investigation of the effect of trehalose on symptoms of a PSP (progressive supranuclear palsy) patient | IRCT20181022041407N5 |
| Piiloset Trehalose Emulsion Eye Drop Study in Moderate or Severe Dry Eye | A Randomized, Active-controlled, Parallel, Double-blind Study on the Safety, Ocular Tolerability and Efficacy of Piiloset Trehalose Emulsion Eye Drop in Adult Patients With Moderate or Severe Dry Eye | NCT03569202 |
| Efficacy of Oral Administration of Trehalose in Patients With Parkinson Disease | Efficacy of Oral Administration of Trehalose in Patients With Parkinson Disease in Both Idiopathic and Induced by LRRK2 Mutation | NCT05355064 |
| Preliminary clinical study of a novel oral mucosal protective solution containing trehalose. –Alleviation of oral dryness caused during dental surgery– | Preliminary clinical study of a novel oral mucosal protective solution containing trehalose. –Alleviation of oral dryness caused during dental surgery– - Preliminary clinical study of a novel oral mucosal protective solution containing trehalose. | JPRN-UMIN000000866 |
| Inflammation Reduction by TREhalose AdminisTration | The Use of Intravenous Trehalose to Reduce Vascular Inflammation in Acute Coronary Syndrome | NCT03700424 |
| The effect of Trehalose on survival in children | Investigating the effect of Trehalose on survival in children admitted to the intensive care unit | IRCT20221129056657N4 |
| The effect of trehalose on Fatigue in MS | Investigation of the effect of trehalose on Fatigue in patients with Multiple Sclerosis (MS) | IRCT20181022041407N8 |
| Investigation of the effect of trehalose on Parkinson disease | Investigation of the effect of trehalose on motor and non-motor symptoms of Parkinson disease patients | IRCT20181022041407N10 |
| Evaluation of the effectiveness of trehalose on autism | Evaluation of the effectiveness of trehalose augmentation on children with autism spectrum disorder (ASD) | IRCT20181022041407N11 |
| Clinical study on tissue adhesion preventive devices Trehalose based novel devices for postoperative tissue adhesions | Clinical study on tissue adhesion preventive devices Trehalose based novel devices for postoperative tissue adhesions - Clinical study on tissue adhesion preventive devices | JPRN-UMIN000000768 |
| Clinical Study of 12-week Trehalose Intake in Patients With Fatty Liver Disease | A 12-week, Randomized, Double-blind, Placebo-controlled, Parallel-group Clinical Study to Evaluate the Efficacy and Safety of Trehalose in Patients With Fatty Liver Disease | NCT03738358 |
| The effect of trehalose on stroke | Investigation of the effect of trehalose on CRP, disability and complication of stroke in ischemic stroke patients: a randomized controlled trial | IRCT20181022041407N7 |
| Effects of Trehalose on Peri-Trochanteric Fractures | Determining the Effects of Trehalose Consumption on Inflammation and Wound Healing in Patients with Peri-Trochanteric Fractures | IRCT20180404039188N5 |
| Investigation of the effect of trehalose on troponin and C-Reactive Protein in patients with myocardial infarction | Investigation of the effect of trehalose on troponin and CRP levels in patients with ST elevation myocardial infarction (STEMI) | IRCT20181022041407N9 |
| Trehalose and diabetes type 2 | Investigation of the effects of oral trehalose supplementation on glycemic control in patients with type 2 diabetes | IRCT20130829014521N18 |
| Use of a Synthetic Macromolecule (Hydroxypropyl Cellulose ) and Trehalose as Additives for Oocyte Vitrification | """Impact of Using Hydroxypropyl Cellulose (HPC) and Trehalose for Oocyte Vitrification in an Ovum Donation Program""" | NCT01745523 |
| The effects of different concentrations of trehalose and dimethyl sulfoxide on the vitrification cryopreservation of human ovarian tissues | The effects of different concentrations of trehalose and dimethyl sulfoxide on the vitrification cryopreservation of human ovarian tissues | ChiCTR-IOR-17011392 |
| Effect of Trehalose on Peri-Trochanteric Fractures | Effects of Trehalose on Bone Healing, Physical Function and Pain in Patients with Peri-Trochanteric Fractures | IRCT20240605062013N1 |
