IMPPAT Phytochemical information: 
vitamin B1

vitamin B1
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
Vitamin B1 as treatment for chronic fatigue in patients with primary biliary cholangitisPBC induced fatigue treated with thiamine- The effect of oral thiamine supplement in 4 weeks to patients with primary biliary cholangitis (PBC) and chronic fatigue.A randomised, double-blinded, placebo-controlled, crossover study - PIFTEUCTR2020-004935-26-DK
Evaluating the effect of thiamine on deliriumEvaluating the preventive effect of vitamin B1 on Delirium in critically ill patientsIRCT20190224042815N1
Influence of vitamin B1 suplementation in oxidative stress, energetic metabolism and mortality among patients with septic shockInfluence of thiamine suplementation in oxidative stress, energetic metabolism and mortality among patients with septic shockRBR-9m6bny
Thiamine ( Intravenous Vitamin B1) induced post–operative analgesia in maxillofacial surgery.Role of thiamine in the management of post–operative analgesia in maxillofacial surgery.IRCT201403061674N11
Effect of high dose vitamin B1 on early stage kidney disease in type 2 diabetesA randomised, double-blind, placebo-controlled study to assess if high dose thiamine therapy of type diabetic patients with microalbuminuria decreases the urinary excretion of albuminAcronym: THIAMACTRI/2008/091/000112
Effectiveness of Vitamin B1 (Thiamine) Supplementation in Infants with Pulmonary Arterial HypertensionNon-Cardiac Pulmonary Arterial Hypertension in Infants Presenting with Respiratory Distress: Assessing the Efficacy of Thiamine Supplementation in a Clinical Setting - NILCTRI/2024/09/073873
Prednisolone and vitamin B1, B6, and B12 in patients with Post-COVID-19-Syndrome (PC19S) – a randomized controlled trial in primary carePrednisolone and vitamin B1, B6, and B12 in patients with Post-COVID-19-Syndrome (PC19S) – a randomized controlled trial in primary care - PreVitaCOVEUCTR2022-001041-20-DE
B1 and Magnesium Supplements on Glucose Metabolism in Low-carb DietersEffects of Vitamin B1 and Magnesium Supplements on Glucose Metabolism in Adults Voluntarily Following Reduced-carbohydrate Diets: a Proof of Concept Intervention StudyNCT04651205
Vitamins and Mg in IBDThe effect of vitamin B1,B6,B12 and magnesium in disease activity, quality of life and chronic fatigue of inflammatory bowel diseaseIRCT20090822002365N28
effect of vitamin B1 on the level of consciousnesseffect of vitamin B1 on the level of consciousness and clinical conditions of patients with decreased level of consciousness hospitalized in intensive care unitsIRCT20210626051710N1
Vitamin B1-6-12 and vitamin B12 to improve the reduced sensation from Bilateral Sagittal Split Ramus Osteotomy: a prospective randomised double blind controlled clinical trialVitamin B1-6-12 and vitamin B12 to improve the reduced sensation from Bilateral Sagittal Split Ramus Osteotomy: a prospective randomised double blind controlled clinical trialTCTR20181030001
Observation on the clinical effect of vigabatrin plus vitamin B1 in the treatment of infantile spasmsObservation on the clinical effect of vigabatrin plus vitamin B1 in the treatment of infantile spasmsChiCTR2100045702
Evaluation of Safety and Dosing of a Vitamin C Bundle for Sepsis Treatment in AfricaEvaluation of Pharmacokinetics, Safety and Feasibility for Administration of Two Doses of Intravenous Vitamin C Combined With Vitamin B1 for the Management of Adult Patients Admitted With Sepsis to Kiruddu National Referral HospitalNCT04999137
Evaluation of the effect of vitamin B1 and B6 in manic patientsEvaluation of the effect of vitamin B1 and B6 as an adjunct therapy to improve the symptoms of mania phase of bipolar disorder type I; in a double-blind and placebo-controlled clinical trialIRCT20200307046712N1
The effect of vitamin B1 (thiamine) on blood pressure, lipid profile, liver enzymes and fasting blood sugar in the military with metabolic syndromeThe effect of vitamin B1 (thiamine) on blood pressure, lipid profile, liver enzymes and fasting blood sugar in patients with metabolic syndromeIRCT20180201038585N5
The protective effect of Thiamine (vitamin B1) for Bortezomib induced peripheral neuropathy in multiple myelomaThe protective effect of Thiamine (vitamin B1) for Bortezomib induced peripheral neuropathy in multiple myelomaIRCT20190116042379N1
Vitamin B1 (thiamine) administration in enterally-fed critically ill patients with hypophosphatemia: A prospective, randomised clinical trialEffect of exogenous vitamin B1 (thiamine) administration on blood lactate concentrations in enterally-fed, critically ill patients with hypophosphatemiaACTRN12619000121167
Vitamin C, Vitamin B1 and Steroid in SepsisEffects of Vitamin C, Thiamine and Hydrocortisone in Septic Shock: a Randomized, Controlled TrialNCT04039815
The Effect of Vitamin B1 on the menstruation’s complicationsThe Effect of Vitamin B1 on the menstruation’s complications Living in a dormitory studentsIRCT2017070710451N2
The effects of calcium and vitamin B1 supplementations on premenstrual syndromeThe effects of calcium and vitamin B1 supplementation on premenstrual syndrome (PMS) in female university students: A randomized clinical controlled trialIRCT2016011810333N3
The comparison of vitamin B1 and placebo effects on the relief of primary dysmenorrheal in university student of Islamic Azad University.The comparison of vitamin B1 and placebo effects on the relief of primary dysmenorrheal in university student of Islamic Azad University.IRCT2014071318458N1
Association between Helicobacter pylori infection and vitamin B1 deficiencyAssociation between Helicobacter pylori infection and vitamin B1 deficiency - Association between H. pylori infection and vitamin B1 deficiencyJPRN-UMIN000012410
The effect of vitamin B1 on the complications after the insertion of Intra uterin deviceThe effect of vitamin B1 on the complications after the insertion of Intra uterin device in women gravid of 1-4IRCT2012073010451N1
Thiamine supplementation in type 2 diabetesOral thiamine (Vitamin B1) supplementation in subjects with type 2 diabetes mellitus: a randomised, double-blind, placebo-controlled crossover trial assessing biophysical markers of endothelial function, oxidant stress, insulin sensitivity and vascular inflammationISRCTN30703970
Evaluating the effects of vitamin B1, B6, B12 and folic acid supplementation in women with episodic migraineEvaluating the effects of vitamin B1, B6, B12 and folic acid supplementation versus placebo on serum levels of CGRP, endothelial nitric oxide synthase, homocysteine and headache characteristics in women with episodic migraineIRCT20190921044828N1
A clinical study done to assess the effects of Vitamin B1 - Vitamin C adjunct therapy in patients with (external forces) traumatic insult to brain.Thiamine - Ascorbic acid adjuvant therapy in Traumatic Brain Injury – A randomized, controlled, parallel-group study - TABCTRI/2019/09/021460
Assessment of the vitamin B1 effect on the outcomes of patients with sepsisAssessment of the vitamin B1 effect on the outcomes of patients with sepsis under mechanical ventilation admitted to the general intensive care unitIRCT20220711055432N1
Prednisolone and vitamin B1, B6, and B12 in patients with Post-COVID-19-Syndrome (PC19S) – a randomized controlled trial in primary carePrednisolone and vitamin B1, B6, and B12 in patients with Post-COVID-19-Syndrome (PC19S) – a randomized controlled trial in primary care - PreVitaCOVDRKS00029617
Assessing the effect of vitamin B1 and vitamin C on treatment of sever sepsisAssessing the effect of vitamin B1 and vitamin C on attenuation of mortality due to sever sepsisIRCT20210518051339N1
Investigating the effect of vitamin B1 oral tablets on the post covid-19 syndromeInvestigating the effect of vitamin B1 oral tablets on the post covid-19 syndrome in comparison with the control groupIRCT20221229056979N1
Beriberi (Vitamin B1 deficiency)- Burden and Intervention study in High burden districts of North East IndiaA study on Prevalence & factors associated with Thiamine deficiency among Pregnant and Lactating mothers living in Assam and Tripura and Assessing the Impact of Health and Nutritional Education as a Sustainable model of Intervention - NILCTRI/2023/07/055337
Vitamin B1 against chronic fatigue in inflammatory bowel diseaseThiamin against robust IBD fatigue- The effect of oral thiamin supplement in 4 weeks to patients with inflammatory bowel disease (IBD) in remission and chronic fatigue.A randomised placebo controlled crossover study - TARIFEUCTR2018-002324-17-DK
The effect of high-dose of vitamin B1 supplementation on episodic migraine in womenThe effect of high-dose of vitamin B1 supplementation on serum CGRP neuropeptide levels and features of episodic migraine in womenIRCT20140804018677N24
Effect of vitamin B1 supplementation on bone metabolic markers in adults with normal kidney functionEffect of vitamin B1 supplementation on bone metabolic markers in adults with normal kidney function - Effect of vitamin B1 supplementation on bone metabolic markers in adults with normal kidney functionJPRN-UMIN000049711
Riboflavin and thiamine dietary nutrition supplementation or reduction of anxiety, stress condition and improvement of sleep quality: A randomized double-blind, placebo-controlled trialAssociation between thiamine (vitamin B1) and riboflavin (vitamin B2) nutrition intervention on anxiety, stress and sleep qualityChiCTR2500096497
Efficacy of Vitamin B1 in Familial Adenomatous Polyposis Patients.Evaluation of the Efficacy of Vitamin B1 in Patients with Familial Adenomatous Polyposis: an Exploratory StudyNCT06649825
STUDYING THE ADVANTAGE OF ADDITIONAL USE OF VITAMIN SUPPLEMENTS (VITAMIN B1 AND VITAMIN C) IN CHILDREN WITH SEVERE DENGUE GETTING ADMITTED IN PEDIATRIC INTENSIVE CARE UNIT.CLINICAL EFFECTIVENESS OF ASCORBIC ACID AND THIAMINE AS ADJUNCTIVE THERAPY IN CHILDREN WITH SEVERE DENGUE REQUIRING PICU (PEDIATRIC INTENSIVE CARE UNIT) CARE- OPEN LABELLED RANDOMISED CONTROLLED TRIAL.CTRI/2019/09/021244
Comparison of the effect of vitamin B1 and duloxetine with gabapentin in the control of diabetic neuropathy painComparison of the effect of vitamin B1 and duloxetine with gabapentin in the control of diabetic neuropathy pain in patients with diabetisIRCT20111009007745N11
Efficiency of combined treatment of clonazepam mouthwash and vitamin B1 and alphalipoic acid supplements in the treatment of idiopathic burning mouthComparison of the effectiveness of clonazepam mouthwash and the combined treatment of clonazepam mouthwash, vitamin B1 and alphalipoic acid supplements on burning of mouth in patients with idiopathic burning mouthIRCT20230413057893N1
Comparative study of effectiveness of intravenous high dose of vitamin C and vitamin B1 in patients with severe infection.To compare efficacy of high dose Vitamin C infusion and Thiamine (vitamin B1) infusion in patients of sepsis. - NILCTRI/2024/03/063852
The effect of Nevazin and vitamin B1 in treatment of chemotherapy-induced neuropathyInvestigating and comparing the therapeutic effect of Nevazin and vitamin B1 in chemotherapy-induced neuropathy in cancer patients undergoing chemotherapyIRCT20230722058878N1
Combination of vitamin C and vitamin B1 in the treatment of early sepsis based on concentration analysisCombination of vitamin C and vitamin B1 in the treatment of early sepsis based on concentration analysisChiCTR2300072751