IMPPAT Phytochemical information: 
Hydroxyprogesterone

Hydroxyprogesterone
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
the effect of progesterone in the prevention of preterm deliveryComparison of the Effects of Vaginal Progesterone (Cyclogest) and Intramuscular Progesterone (Hydroxyprogesterone Caproate) in the Prevention of Preterm LaborIRCT2015040921670N1
Vaginal Progesterone Versus 17-Alpha-Hydroxyprogesterone Caproate in Placenta PreviaVaginal Progesterone Versus 17-Alpha-Hydroxyprogesterone Caproate for Prevention of Emergent Cesarean Delivery in Asymptomatic Pregnant Women With Placenta Previa: A Randomized Controlled StudyNCT03779451
effect of progestron in preterm laborComparing the efficacy of vaginal progesterone (cyclogest) versus injection of 17a hydroxyprogesterone caproate ( proluton) in preventing of preterm brth less than 34 weeks gestation in pregnant women with threatend abortion in Arash HospitaIRCT2014123120504N1
Relationship Between Plasma Concentration of Hydroxyprogesterone Caproate (17-OHPC) and Preterm BirthRelationship Between Plasma Concentration of (Hydroxyprogesterone Caproate) 17-OHPC and Preterm BirthNCT03292731
Treatment of Preterm Labor With 17 Alpha-hydroxyprogesterone CaproateNCT00120640
Intramuscular Hydroxyprogesterone Caproate and Placenta PreviaThe Use Of Intramuscular Hydroxyprogesterone Caproate For Management Of Placenta Previa Before 34 Weeks Of GestationNCT03130504
Study Assessing Injection Pain of Makena® (Hydroxyprogesterone Caproate Injection, 250 mg/mL) When Administered Via Subcutaneous Auto-injector vs Intramuscular Injection Via Needle and Syringe in Healthy Post-menopausal WomenA Phase III, Single-Center, Open-labeled, Randomized Controlled Study Assessing Injection Pain of Preservative-free Makena® (Hydroxyprogesterone Caproate Injection, 250 mg/mL) When Administered Via Subcutaneous Auto-injector vs Intramuscular Injection Via Needle and Syringe in Healthy Post-menopausal WomenNCT02937766
Effect of 17 a-Hydroxyprogesterone caproate on prevention of preterm labor.A clinical trial to comparison the effectiveness of 17 a-Hydroxyprogesterone caproate with routine prenatal care on prevention of preterm labor in patients with a history of preterm labor.IRCT20190309042978N2
Comparing Bioavailability When Preservative-free Makena® (Hydroxyprogesterone Caproate Injection, 250 mg/mL) is Administered as an Intramuscular Manual Injection or as a Subcutaneous Injection Using an Auto-injector in Healthy Post-menopausal WomenA Multi-Center, Randomized, Open-Label Study Comparing Bioavailability When Preservative-free Makena® (Hydroxyprogesterone Caproate Injection, 250 mg/mL) is Administered as an Intramuscular Manual Injection or as a Subcutaneous Injection Using an Auto-injector in Healthy Post-menopausal WomenNCT02940522
17-OHPC in Pregnancy: IM vs SC RoutesA Comparison of Intramuscular and Subcutaneous Administration of 17-hydroxyprogesterone Caproate (17-OHPC) in PregnancyNCT04183452
To see the effect of INj proluton if given before surgery in patients with high risk operable breast cancer.�A Phase III Randomized Controlled study of Inj. Proluton (Hydroxyprogesterone caproate) as single dose preoperative therapy in patients with high risk operable breast cancer.�CTRI/2014/10/005098
Single Injection 17-hydroxyprogesterone caproate in Preterm labour: a randomised controlled trialISRCTN22145023
An assessment of effect of pre operative Proluton in patients with operable breast cancerAn assessment of the effect of preoperative hydroxyprogesterone on serial levels of circulating tumour cells and serum nucleic acids (DNA and chromatin) in patients undergoing surgery for operable breast cancer.CTRI/2014/11/005229
17OHP-C Dosing Among Obese Pregnant WomenImpact of a Higher Dose on the Pharmacokinetics of 17-alpha Hydroxyprogesterone Caproate in Obese WomenNCT03433040
Progesterone in Expectantly Managed Early-onset PreeclampsiaEfficacy of 17-Hydroxyprogesterone Caproate in Expectantly Managed Early-onset Preeclampsia: A Randomized Controlled StudyNCT04077853
Trial of Progesterone in Twins and Triplets to Prevent Preterm Birth (STTARS)A Randomized Trial of 17 Alpha-Hydroxyprogesterone Caproate for Prevention of Preterm Birth in Multifetal Gestation (STTARS)NCT00099164
Effect of proluton and cyclogest on perinatal outcomeComparing the efficacy of 17a hydroxyprogesterone caproate ( proluton) versus vaginal progesterone (cyclogest) on perinatal outcome in high risk patients who undergo cerclageIRCT20181107041585N4
Pharmacokinetic Study of Makena® (Hydroxyprogesterone Caproate Injection, 250 mg/mL) and Its Metabolites in BloodA Multi-Center, Non-Randomized Pharmacokinetic Study of Makena® (Hydroxyprogesterone Caproate Injection, 250 mg/mL) and Its Metabolites in Blood of Women With a Singleton Pregnancy and a Previous Singleton Spontaneous Preterm DeliveryNCT01899846
17-alpha-hydroxyprogesterone caproate versus vaginal progesterone suppository for the prevention of preterm birth in women with a sonographic short cervix17-alpha-hydroxyprogesterone caproate versus vaginal progesterone suppository for the prevention of preterm birth in women with a sonographic short cervix in ARASH hospital during 2012-2013 yearsIRCT2012082610664N1
Prevention of Preterm Labor in Patients With a Previous Episode of Threatened Preterm Labor With ProgesteroneUse of 17a Hydroxyprogesterone Caproate for the Prevention of Preterm Labor in Patients With a Previous Episode of Threatened Preterm Labor During Current Pregnancy. Double Blind, Randomized, Controlled Trial.NCT01317225
Progesterone (17P, Makena®) for Prolongation of Pregnancy in Women With Preterm Rupture of the Membranes (PROM)17-alpha-Hydroxyprogesterone Caproate (17P, Makena®) for Prolongation of Pregnancy in Women With Preterm Rupture of the Membranes (PROM), Double-blinded Randomized Clinical TrialNCT01119963
Confirmatory Study of 17P Versus Vehicle for the Prevention of Preterm Birth in Women With a Previous Singleton Spontaneous Preterm DeliveryA Phase 3B, Multi-Center, Randomized, Double-Blind Study of Hydroxyprogesterone Caproate Injection, 250 mg/mL, Versus Vehicle for the Prevention of Preterm Birth in Women With a Previous Singleton Spontaneous Preterm DeliveryNCT01004029
17 Alfa Hydroxyprogesterone Caproate Versus Natural Progesterone for the Prevention of Preterm LaborNCT00809939
A Randomized Trial of Cerclage Versus 17 a-Hydroxyprogesterone Caproate for Treatment of a Short CervixHistologic Evaluation of the Cervix at Risk for Preterm Birth Trial:Medical Versus Surgical TherapyNCT00694967
RCT of Progesterone to Prevent Preterm Birth in Nulliparous Women With a Short CervixA Randomized Trial of 17 Alpha-Hydroxyprogesterone Caproate for Prevention of Preterm Birth in Nulliparous Women With a Short CervixNCT00439374
17OHP for Reduction of Neonatal Morbidity Due to Preterm Birth (PTB) in Twin and Triplet Pregnancies17-Alpha-Hydroxyprogesterone Caproate for Reduction of Neonatal Morbidity Due to Preterm Birth in Twin and Triplet Pregnancies - A Concurrent Randomized Double-blinded Clinical TrialNCT00163020
Prevention of Preterm Delivery in Twin Pregnancies by 17 Alpha-hydroxyprogesterone CaproatePrevention of Preterm Delivery in Twin Pregnancies by 17 Alpha-hydroxyprogesterone CaproateNCT00141908
A randomized controlled trial study on the effectiveness of 17 alpha hydroxyprogesterone and micronised progesterone in preventing preterm labor of pregnant women with arrested premature labor.A randomized controlled trial study on the effectiveness of 17 alpha hydroxyprogesterone and micronised progesterone in preventing preterm labor of pregnant women with arrested premature labor.TCTR20210407003
comparison of oral Dydrogesterone and 17a Hydroxyprogesterone Caproate in prevention of preterm birth in patients with preterm laborcomparison of oral Dydrogesterone and 17a Hydroxyprogesterone Caproate in prevention of preterm birth in patients with preterm laborIRCT20181207041879N1