IMPPAT Phytochemical information: 
15R-PGA2 methyl ester, 15-acetate

15R-PGA2 methyl ester, 15-acetate
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
Clinical efficacy of hydroquinone in glaucoma patients with prostaglandin-induced eyelid pigmentationClinical efficacy of hydroquinone in glaucoma patients with prostaglandin-induced eyelid pigmentation - Clinical efficacy of hydroquinone in prostaglandin-induced eyelid pigmentationJPRN-UMIN000011524
Prostaglandin E1 (Liprostin) Treatment With Lower Limb Angioplasty for Peripheral Arterial Occlusive DiseasePhase II, Single Center, Non-Controlled, Open-Label Study of Liposomal Prostaglandin E1 (Liprostin) as Adjunct Therapy With Lower Limb Angioplasty in Patients With Ischemic and Non-Ischemic Peripheral Arterial Occlusive DiseaseNCT00053716
A randomized, double blind, placebo-controlled, 2-period cross over study to evaluate effects of S-555739 on prostaglandin D2 (PGD2) induced nasal airway resistance in healthy adult volunteersA randomized, double blind, placebo-controlled, 2-period cross over study to evaluate effects of S-555739 on prostaglandin D2 (PGD2) induced nasal airway resistance in healthy adult volunteersEUCTR2008-006787-11-GB
Randomised comparison of the nitric oxide donor isosorbide mononitrate with prostaglandin E2 gel for cervical ripening prior to the induction of labour at termISRCTN58088708
Effect of SIMBRINZA® Suspension as an Added Therapy to a Prostaglandin AnalogueAdditive Effect of Brinzolamide 1%/Brimonidine 0.2% Fixed Dose Combination as Adjunctive Therapy to a Prostaglandin AnalogueNCT01937312
The effect's of curcuma, black pepper, ginger on inflammatory marker and pain in the patient with knee osteoarthritisThe effects of curcuma, black pepper and ginger on prostaglandin E2 inflammatory marker and pain in patients with knee osteoarthritis in comparison with NaproxenIRCT2017070511763N32
The Impact of Topical Prostaglandins on the Biomechanical Properties of the Cornea in Patients With Open Angle GlaucomaThe Impact of Topical Prostaglandin Analogs on the Biomechanical Properties of the Cornea in Patients With Open Angle GlaucomaNCT02388360
SIMBRINZA® Suspension BID as an Adjunctive to Prostaglandin Analogue (PGA)Additive Effect of Twice Daily Brinzolamide 1%/Brimonidine 0.2% Fixed Dose Combination as an Adjunctive Therapy to a Prostaglandin AnalogueNCT02419508
Laser compared to topical medicine as primary treatment for glaucoma in AfricaTo compare selective laser trabeculoplasty (SLT) with prostaglandin analogue as first line therapy in African Primary Open Angle Glaucoma (POAG) patientsISRCTN27208571
Effects of a Cyclic NSAID Regimen on Levels of Prostaglandin-E2 and Interleukin-1beta in Gingival Crevicular Fluid of Subjects with Periodontitis: A Randomised Clinical TrialEffects of a Cyclic NSAID Regimen on Levels of Prostaglandin-E2 and Interleukin-1beta in Gingival Crevicular Fluid of Subjects with Periodontitis: A Randomised Clinical TrialTCTR20160202001
Tearing of Membranes Before Birth - a Comparison Between Two Ways of Induction of Labor Pitocin Opposite ProstaglandinTearing of Membranes Before Birth - a Comparison Between Two Ways of Induction of Labor Pitocin Opposite ProstaglandinNCT02720978
Oxytocin vs. Prostaglandin for Induction of Labor in Primiparas With Prelabor Rupture of Membrane and Low BishopOxytocin vs. Prostaglandin for Induction of Labor in Primiparas With Prelabor Rupture of Membrane and Low Bishop Score: Randomized Control StudyNCT02801227
Oral misoprostal for the induction of labour at termOral misoprostol versus vaginal prostaglandin E2 for the induction of labour at term (beyond 37 weeks gestation).ACTRN12606000156583
A study to find the better method to assess the neck of the womb before artificially starting the process of child birth by inserting a drug called “Dinoprostone” (prostaglandin) through the birth passageA randomized controlled trial to compare, sonographically measured cervical length with modified Bishop Score in determining the requirement for prostaglandin administration for preinduction cervical ripening in nulliparae at termSLCTR/2014/027
Comparison of different approaches to labour induction among multi parous women at termInduction of multiparous women at term using different methods: Prostaglandin E2 (dinopristone) vaginal gel, intracervical foley catheter insertion and sweeping of membrane: An open-label, randomised controlled trial.SLCTR/2014/025
Effect of Latanaprost eye drop on retina after cataract surgery in glaucoma patientsEffect of continuation of prostaglandin analogue use on the incidence of Cystoid Macular Edema (CME) following uncomplicated cataract surgery in glaucoma patientsIRCT2016081329326N1
Comparison Between the Effectiveness of Fixed Combinations of Prostaglandin AnaloguesComparison Between the Effectiveness of Fixed Combinations of Prostaglandin Analogues Regarding Intraocular Pressure ControlACTRN12610001034022
Prostaglandin E1 in Outpatients With Intermittent ClaudicationIntravenous Prostaglandin E1 Treatment in Outpatients With Intermittent ClaudicationNCT01263925
Efficacy of prostaglandin E1 (alprostadil alfadex) in hemodialysis patients with peripheral arterial disease (PAD): Examination of the therapeutic effect based on measurement of skin perfusion pressure (SPP)Efficacy of prostaglandin E1 (alprostadil alfadex) in hemodialysis patients with peripheral arterial disease (PAD): Examination of the therapeutic effect based on measurement of skin perfusion pressure (SPP) - Efficacy of prostaglandin E1 (alprostadil alfadex) in hemodialysis patients with PADJPRN-UMIN000005169
Prostaglandin F2alpha in a Human Headache ModelHeadache Inducing Characteristics and Possible Changes in Cerebral Blood Flow After Administration of Prostaglandin F2alphaNCT01327118
CONFIRMATORY, PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL GROUPS STUDY TO ASSESS THE EFFICACY AND SAFETY OF PROSTAGLANDIN E1 IN SUBJECTS WITH DRY AGE-RELATED MACULAR DEGENERATION - AIMSCONFIRMATORY, PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL GROUPS STUDY TO ASSESS THE EFFICACY AND SAFETY OF PROSTAGLANDIN E1 IN SUBJECTS WITH DRY AGE-RELATED MACULAR DEGENERATION - AIMSEUCTR2005-005686-11-AT
Prospective clinical study of the therapeutic effects of prostaglandin in patients with combined lumbar spinal stenosis and arteriosclerosis obliterans showing intermittent claudicationProspective clinical study of the therapeutic effects of prostaglandin in patients with combined lumbar spinal stenosis and arteriosclerosis obliterans showing intermittent claudication - Clinical study on therapeutic effects of prostaglandin in patients with combined lumbar spinal stenosis and arteriosclerosis obliteransJPRN-UMIN000005959
Extra-Amniotic Normal Saline Infusion plus Hydrocortisone versus Prostaglandin E2 Suppository for Pregnancy TerminationComparison of Extra-Amniotic Normal Saline Infusion plus Hydrocortisone versus Prostaglandin E2 Suppository for Pregnancy TerminationIRCT201109107520N1
Prostaglandin gel versus oxytocin for induction of labour in term prelabour rupture of membranesFor women with term prelabour rupture of membranes who wish active management does use of PG gel result in better satisfaction and less need for oxytocin without increasing risk of neonatal sepsis.ACTRN12612000093886
Ocular surface evaluation in ocular hypertension or inicial glaucoma patients treated with drops.Ocular surface evaluation in patients treated with prostaglandin analogues or timolol maleate monotherapy compared to patients treated with fixed combination of prostaglandin analogues and timolol maleate 0,5% monotherapyRBR-7mmp6k
Ischemia Reperfusion: Prostaglandins and AntioxidantsThe Role of Prostaglandin and Anti-oxidant Availability on Recovery From Forearm Ischemia-reperfusion Injury in HumansNCT01666587
The Secondary Beneficial Effects of Prostaglandin Analog Treatment in Thyroid Eye Disease Patients.The Secondary Beneficial Effects of Prostaglandin Analog Treatment in Thyroid Eye Disease Patients.NCT01927406
A comparison of the effectiveness of prostaglandin gel and tablet preparations in induction of labour at term.A comparison of the effectiveness of prostaglandin gel and tablet preparations in induction of labour at term.EUCTR2004-003797-28-GB
A Clinical Trial to study the benefit of the drug Prostaglandin E1 (a vessel that basically dilates the blood vessels) in patients who undergo Living Donor Liver TransplantationRole of Perioperative Prostaglandin E1 infusion in patients undergoing living donor liver transplantation : a Double blind Randomised trialCTRI/2013/09/003991
Intracavernous injections of prostaglandin E1 for erectile dysfunction:multicenter studyIntracavernous injections of prostaglandin E1 for erectile dysfunction:multicenter study - Intracavernous injections of prostaglandin E1 for erectile dysfunction:multicenter studyJPRN-UMIN000012394
Vaginal Prostaglandin E2 versus oxytocin for induction of labour in women with pre-labour rupture of membranes at termVaginal Prostaglandin E2 versus oxytocin for induction of labour in women with pre-labour rupture of membranes at termSLCTR/2014/008
Factors related with prostaglandin associated periorbitopathy (PAP) in glaucoma patientsFactors related with prostaglandin associated periorbitopathy (PAP) in glaucoma patientsTCTR20141011001
Ocular circulation changes and intraocular pressure reduction induced by ripasudil or dorzolamido/timolol fixed combination added to prostaglandin agalogues in primary open angle glaucomaOcular circulation changes and intraocular pressure reduction induced by ripasudil or dorzolamido/timolol fixed combination added to prostaglandin agalogues in primary open angle glaucoma - Ocular circulation changes and intraocular pressure reduction induced by ripasudil or dorzolamido/timolol fixed combination added to prostaglandin agalogues in primary open angle glaucomaJPRN-UMIN000027047
Effects of Prostaglandin Analogue Washout Following Long-term Therapy in Adults With Primary Open Angle GlaucomaProspective, Randomized, Single-blind Controlled Trial of Topical Prostaglandin Analogue Washout Following Chronic Monotherapy in Adults With Suspected or Proper Primary Open Angle GlaucomaNCT03534882
The Effect of Prostaglandin I2 on the Endothelial Cell Function Disorder in Type 2 Diabetes Mellitus PatientsThe Effect of Prostaglandin I2 (Beraprost Na), Administered Orally for Eight Weeks, on the Endothelial Cell Functional Disorder in Type II Diabetes Mellitus Patients With Symptoms of a Minute Peripheral Blood Flow DisorderNCT01061060
Evaluation of the impact of Prostaglandin E1 injection and Low Level Laser therapy on duration of Braces TreatmentComparison and evaluation of the effects of Prostaglandin E1 injection with Low Level Laser therapy on Orthodontic tooth movement- An In Vivo study - NILCTRI/2025/03/082785
Exploring 8-iso Prostaglandin F2a and Adenosine Deaminase Levels in Periodontal Health and DiseaseExploring 8-iso Prostaglandin F2a and Adenosine Deaminase Levels in Periodontal Health and DiseaseNCT06236555
Role of Prostaglandins on Niacin-Induced FlushingExploring the Role of Prostaglandin D2 and the DP1 Receptor on Nicotinic Acid Induced FlushingNCT00930839
Biosynthesis of PGD2 in VivoA Pilot Study to Measure Plasma and Urinary Prostaglandin D2 Metabolites Evoked by NiacinNCT01275300
COMPARISON OF EFFICACY OF GLUCOSAMINE AND CHONDROITIN SULPHATE VS VITAMIN C IN PATIENTS WITH GUM DISEASECOMPARISON OF EFFICACY OF GLUCOSAMINE AND CHONDROITIN SULPHATE VS VITAMIN C AS ADJUVANTS TO NONSURGICAL PERIODONTAL THERAPY ON PROSTAGLANDIN E2 LEVELS IN CHRONIC PERIODONTITIS PATIENTS-A CASE CONTROL STUDY.CTRI/2021/10/037359
The influence of prostaglandins and prostaglandin receptors on the cervix opening at the end of pregnancy and at the beginning of laborThe influence of prostaglandins and prostaglandin receptors on the cervix opening at the end of pregnancy and at the beginning of laborDRKS00017221
Prostaglandin Analog Eyelash Serum and Ocular Surface Health: A Prospective StudyEffects of a Prostaglandin Analog-Based Eyelash Serum on Ocular Surface Integrity and Tear Film Stability: A Prospective Interventional StudyNCT06875687
Changes in Biomarkers Using Prostaglandin InhibitorsProstaglandin Inhibition to Prevent Breast CancerNCT01769625
Changes in Breast Cancer Biomarkers Using Synergistic Prostaglandin InhibitorsBreast Cancer Prevention Using Synergistic Prostaglandin Inhibitors (The Vitamin D/Celecoxib Study)NCT01425476
Prostaglandin E2 as a Critical Mediator of Sex Disparities in AsthmaProstaglandin E2 as a Critical Mediator of Sex Disparities in AsthmaNCT03825302
Analgesic Strategies in Newborns Receiving Prostaglandin TherapyAnalgesic Strategies in Newborns Receiving Prostaglandin TherapyNCT00200590
Assessment of the effect of aspirin on periapical inflammationAssessment of the effect of aspirin on levels of lipoxin A4? interleukin-1ß and prostaglandin E2 in periapical exudates: a double blinded randomized clinical trialIRCT20191211045702N1
To compare the usefulness of aescin and diclofenac sodium in managing pain, swelling, mouth opening after lower third molar surgery.Comparison of the efficacy of aescin as against diclofenac sodium in the management of postoperative sequelae and their effect on salivary Prostaglandin E2 and serum C–reactive protein levels after surgical removal of impacted mandibular third molar: a randomized, double-blind, controlled clinical trial. - NILCTRI/2023/09/058004
Vitamin D Supplementation on 15-Prostaglandin Dehydrogenase Expression in Barrett's EsophagusEffect of Vitamin D Supplementation on 15-Prostaglandin Dehydrogenase Expression in Barrett's EsophagusNCT01465113
Cholecalciferol(25-[OH]-Vitamin D) in Treating Patients With Colorectal CancerEvaluation of the Effect of 25-OH-Vitamin D3 Therapy on 15-Prostaglandin Dehydrogenase Expression in Primary Tumor and Normal Colorectal Mucosa in Patients With Colorectal CancerNCT01403103
Comparison of vaginal prostaglandin E2 gel and tablets for the induction of labor at term: a randomized controlled trial.Comparison of vaginal prostaglandin E2 gel and tablets for the induction of labor at term: a randomized controlled trial.SLCTR/2017/019
Studying the effect of treating hypopigmented scars with prostaglandin analogs throughfractional erbium yag laser assisted drug deliveryStudying the effect of treating hypopigmented scars with prostaglandin analogs throughfractional erbium yag laser assisted drug deliveryDuring the years 2024 to 2025 in patients referred to the laser department of Razi Hospital in TehranIRCT20241016063390N1
Labor Induction with Foley catheter and E1-prostaglandin analogs in Poland (LIFE-PL Study)A prospective randomized controlled trial (RCT) evaluating the effectiveness of a pharmacological pre-induction and induction of labor protocol using an oral prostaglandin E1 analogue and oxytocin compared to a protocol of mechanical pre-induction and induction of labor using a single-balloon Foley catheter, in and oxytocin in patients scheduled for induction of labor.ISRCTN89250117
A multicenter, randomized, open label, parallel controlled trial for evaluating the efficacy and safety prostaglandin and beraprost sodium in the treatment of patients with type 2 diabetes and abnormal ABI but no typical intermittent claudication symptomsA multicenter, randomized, open label, parallel controlled trial for evaluating the efficacy and safety prostaglandin and beraprost sodium in the treatment of patients with type 2 diabetes and abnormal ABI but no typical intermittent claudication symptomsChiCTR1800017817
A Multicenter Clinical Trial of Chuanhuang combined with prostaglandin E1 in treatment of A on CA Multicenter Clinical Trial of Chuanhuang combined with prostaglandin E1 in treatment of A on CChiCTR1800018411
Efficacy of IOP reduction and safety of Eybelis ophthalmic solution 0.002% switched from Prostaglandin analog.Efficacy of IOP reduction and safety of Eybelis ophthalmic solution 0.002% switched from Prostaglandin analog. - Efficacy of IOP reduction and safety of Eybelis ophthalmic solution 0.002% switched from Prostaglandin analog.JPRN-UMIN000035193
comparative study of onset of labour using 2 forms of prostaglandinsComparison of Prostaglandin E2 gel and Prostaglandin pessary E2 in an Unfavorable Cervix for induction of labour: A Randomized Trialâ??CTRI/2019/08/020771
Effects of Prostaglandin E1 Treatment on Pyloric Wall in NewbornsEffect Of Prostaglandin E1 Treatment On Pyloric Wall Thickness in Newborns With Ductal Dependent Critical Congenital Heart DiseasesNCT04496050
Comparison of safety and efficacy of chemical method vs mechanical method in inducing labour pains in a term pregnant motherComparative study of safety and efficacy of intracervical Foley catheter balloon versus prostaglandin E2 gel for induction of labour in unfavourable cervixCTRI/2020/08/027093
Comparative study of efficacy of Prostaglandin F2A gel alone and mifepristone with ProstaglandinF2A gel as cervical ripening agentComparative study of efficacy of dinoprostone gel alone and mifepristone with dinoprostone gel as cervical ripening agent - NILCTRI/2024/05/067880
Cri Analog PG1 Effectiveness and Safety in Covid-19Effectiveness and Safety of the Administration of Intravenous Prostaglandin E1 Analog in the Reduction of Mortality and Complications of Patients With COVID-19NCT04536363
Prostaglandin analogs for preventing the progression of diabetic nephropathyProstaglandin analogs for preventing the progression of diabetic nephropathyChiCTR2000040170
Evaluation of glaucoma or ocular hypertension patients with pre-existing ocular surface disease switched from a preserved prostaglandin analog – timolol fixed combination to a preservative – free latanoprost – timolol fixed combinationEvaluation of glaucoma or ocular hypertension patients with pre-existing ocular surface disease switched from a preserved prostaglandin analog – timolol fixed combination to a preservative – free latanoprost – timolol fixed combinationDRKS00024581
PSLT Compared to Prostaglandin Analogue Eye DropsComputer-guided Selective Laser Trabeculoplasty (PSLT) in the Treatment of Ocular Hypertension and Open-angle Glaucoma Compared to Prostaglandin Analogue Eye Drops: a Non-inferiority Randomized Clinical TrialNCT05241938
Laminaria Tents Versus Vaginal Prostaglandin in Cervical RipeningLaminaria Tents Versus Vaginal Prostaglandin in Cervical Ripening in Term Induction of Labor With Unfavorable Cervix:A Randomized Controlled TrialNCT06151925
Evaluation of retinal thickness in patients with Glaucoma using Prostaglandin eye drops undergoing Trabeculectomy surgeryEvaluation of Macular Thickness in patients with Glaucoma in use of Prostaglandin Analogue undergoing Trabeculectomy with Mitomycin CRBR-5y44mmj
The patient-reported outcome of postoperative Prostaglandin E1 derivative in Lumbar spine surgery: a randomized, double-blinded, controlled trialThe patient-reported outcome of postoperative Prostaglandin E1 derivative in Lumbar spine surgery: a randomized, double-blinded, controlled trialTCTR20201010003
The Use of Prostaglandin E1 in Head and Neck MicrosurgeryPhase 4 Study of Postoperative Prostaglandin E1 in Head and Neck MicrosurgeryNCT00733434