Resistance profile for Ivermectin

Resistance Summary
Resistance Factor (RF):
RF = LC50 (field isolate) / LC50 (susceptible isolate)
Resistance Level (RL):
Level RF Range
Susceptible (S)< 1.4
I1.5 – 5
II5.1 – 25
III26 – 40
IV> 41
Reference DOI: 10.1016/j.vetpar.2011.04.030

Note: Resistance factor (RF) thresholds are based on published studies and may vary across systems. LC50 of susceptible isolates is not location-specific and therefore not directly comparable across studies.
Species Stage State District Area Test Type LC50 Unit Resistance Factor Level Reference
Hyalomma anatolicum Adult Gujarat Banaskantha Kankrej Adult immersion test 20.14 ppm 4.2 I 34329928
Hyalomma anatolicum Adult Gujarat Patan Saraswati Adult immersion test 6.87 ppm 1.43 I 34329928
Hyalomma anatolicum Adult Gujarat Banaskantha Vadgam Adult immersion test 13.03 ppm 2.72 I 34329928
Hyalomma anatolicum Adult Gujarat Banaskantha Palanpur Adult immersion test 97.8 ppm 20.42 II 34329928
Hyalomma anatolicum Adult Gujarat Banaskantha Danta Adult immersion test 249.35 ppm 52.06 IV 34329928
Hyalomma anatolicum Adult Gujarat Kutch Bhachau Adult immersion test 6.39 ppm 1.33 S 34329928
Hyalomma anatolicum Adult Gujarat Patan Sidhpur Adult immersion test 15.72 ppm 3.28 I 34329928
Rhipicephalus microplus Larvae Punjab Fazilka Larval packet test 45.86 ppm 13.44 II 40914407
Rhipicephalus microplus Adult Madhya Pradesh Ujjain Adult immersion test 75.21 ppm 3.46 I 37468088
Rhipicephalus microplus Adult Punjab Ludhiana Adult immersion test 108.02 ppm 4.98 I 37468088
Rhipicephalus microplus Larvae Madhya Pradesh Barwani Larval packet test 8.75 ppm 1.01 S 37468088
Rhipicephalus microplus Larvae Madhya Pradesh Damoh Larval packet test 11.52 ppm 1.33 S 37468088
Rhipicephalus microplus Larvae Madhya Pradesh Indore Larval packet test 3.68 ppm 0.42 S 37468088
Rhipicephalus microplus Larvae Madhya Pradesh Jabalpur Larval packet test 7.56 ppm 0.87 S 37468088
Rhipicephalus microplus Larvae Madhya Pradesh Katni Larval packet test 6.32 ppm 0.73 S 37468088
Rhipicephalus microplus Larvae Madhya Pradesh Khandwa Larval packet test 6.5 ppm 0.75 S 37468088
Rhipicephalus microplus Larvae Madhya Pradesh Mandla Larval packet test 9.38 ppm 1.09 S 37468088
Rhipicephalus microplus Larvae Madhya Pradesh Mandsaur Larval packet test 8.5 ppm 0.98 S 37468088
Rhipicephalus microplus Larvae Madhya Pradesh Narsinghpur Larval packet test 9.79 ppm 1.13 S 37468088
Rhipicephalus microplus Larvae Madhya Pradesh Shajapur Larval packet test 21.6 ppm 2.51 I 37468088
Rhipicephalus microplus Larvae Madhya Pradesh Ujjain Larval packet test 7.4 ppm 0.86 S 37468088
Rhipicephalus microplus Larvae Punjab Ludhiana Larval packet test 87.34 ppm 10.15 II 37468088
Rhipicephalus microplus Adult Madhya Pradesh Damoh Adult immersion test 59.28 ppm 2.73 I 35917692
Rhipicephalus microplus Adult Madhya Pradesh Jabalpur Adult immersion test 67.17 ppm 3.09 I 35917692
Rhipicephalus microplus Adult Madhya Pradesh Katni Adult immersion test 72.83 ppm 3.35 I 35917692
Rhipicephalus microplus Adult Madhya Pradesh Mandla Adult immersion test 40.99 ppm 1.89 I 35917692
Rhipicephalus microplus Adult Punjab Ludhiana Adult immersion test 108.02 ppm 4.98 I 35917692
Rhipicephalus microplus Larvae Jammu and Kashmir Bathindi Larval immersion test 22 ppm 6.45 II 35512539
Rhipicephalus microplus Larvae Jammu and Kashmir Kathua Larval immersion test 21.5 ppm 6.3 II 35512539
Rhipicephalus microplus Larvae Jammu and Kashmir RS Pura Larval immersion test 24.1 ppm 7.07 II 35512539
Rhipicephalus microplus Larvae Jammu and Kashmir Vijaypur Larval immersion test 20.8 ppm 6.09 II 35512539
Rhipicephalus microplus Larvae Jammu and Kashmir Udhampur Larval immersion test 20.3 ppm 5.95 II 35512539
Rhipicephalus microplus Larvae Jammu and Kashmir Miran Sahib Larval immersion test 19.5 ppm 5.72 II 35512539
Rhipicephalus microplus Larvae Jammu and Kashmir Badhori-Phalla Larval immersion test 21.5 ppm 6.3 II 35512539
Rhipicephalus microplus Larvae Jammu and Kashmir Arnia Larval immersion test 20.2 ppm 5.92 II 35512539
Rhipicephalus microplus Larvae Jammu and Kashmir Doda Larval immersion test 9.44 ppm 2.77 I 35512539
Rhipicephalus microplus Larvae Jammu and Kashmir Sumbli Larval immersion test 9.4 ppm 2.76 I 35512539
Rhipicephalus microplus Larvae Jammu and Kashmir Bhagwati Nagar Larval immersion test 21.3 ppm 6.25 II 35512539
Rhipicephalus microplus Larvae Jammu and Kashmir Kunjwani Larval immersion test 20.7 ppm 6.07 II 35512539
Rhipicephalus microplus Larvae Jammu and Kashmir Rajouri Larval immersion test 26 ppm 7.62 II 35512539
Rhipicephalus microplus Larvae Jammu and Kashmir Kishtwar Larval immersion test 5.4 ppm 1.58 I 35512539
Rhipicephalus microplus Larvae Jammu and Kashmir Padder Larval immersion test 4.19 ppm 1.23 S 35512539
Rhipicephalus microplus Larvae Jammu and Kashmir Bhaderwah Larval immersion test 8.37 ppm 2.45 I 35512539
Rhipicephalus microplus Adult Uttarakhand Dehradun Adult immersion test 33.6 ppm 1.55 I 34766246
Rhipicephalus microplus Adult Uttarakhand Tehri Adult immersion test 70.9 ppm 3.27 I 34766246
Rhipicephalus microplus Adult Uttarakhand Haridwar Adult immersion test 48.6 ppm 2.24 I 34766246
Rhipicephalus microplus Adult Uttarakhand Nainital Adult immersion test 50 ppm 2.31 I 34766246
Rhipicephalus microplus Adult Uttarakhand Uttarkashi Adult immersion test 68.2 ppm 3.14 I 34766246
Rhipicephalus microplus Adult Uttar Pradesh Chitrakoot Adult immersion test 48.98 ppm 2.26 I 34542704
Rhipicephalus microplus Adult Uttar Pradesh Sultanpur Adult immersion test 41.69 ppm 1.92 I 34542704
Rhipicephalus microplus Adult Uttar Pradesh Varanasi Adult immersion test 30.19 ppm 1.39 S 34542704
Rhipicephalus microplus Adult Uttar Pradesh Ayodhya Adult immersion test 38.9 ppm 1.79 I 34542704
Rhipicephalus microplus Adult Uttar Pradesh Amethi Adult immersion test 22.39 ppm 1.03 S 34542704
Rhipicephalus microplus Adult Uttar Pradesh Prayagraj Adult immersion test 26.92 ppm 1.24 S 34542704
Rhipicephalus microplus Adult Uttar Pradesh Pratapgarh Adult immersion test 27.54 ppm 1.27 S 34542704
Rhipicephalus microplus Adult Haryana Kurukshetra Adult immersion test 20 ppm 0.925 S 34537543
Rhipicephalus microplus Adult Haryana Karnal Adult immersion test 55.3 ppm 2.55 I 34537543
Rhipicephalus microplus Adult Haryana Ambala Adult immersion test 84.1 ppm 3.87 I 34537543
Rhipicephalus microplus Adult Haryana Panipat Adult immersion test 43.4 ppm 2 I 34537543
Rhipicephalus microplus Adult Haryana Yamuna Nagar Adult immersion test 29 ppm 1.33 S 34537543
Rhipicephalus microplus Adult Haryana Kaithal Adult immersion test 26.17 ppm 1.2 S 34537543
Rhipicephalus microplus Adult Gujarat Jamnagar Adult immersion test 14.75 ppm 0.68 S 34537543
Rhipicephalus microplus Adult Gujarat Somnath Adult immersion test 5.98 ppm 0.275 S 34537543
Rhipicephalus microplus Adult Gujarat Bhawnagar Adult immersion test 6.5 ppm 0.299 S 34537543
Rhipicephalus microplus Adult Gujarat Ahmedabad Adult immersion test 7.35 ppm 0.339 S 34537543
Rhipicephalus microplus Adult Gujarat Junagarh Adult immersion test 4.6 ppm 0.212 S 34537543
Rhipicephalus microplus Adult Gujarat Porbandar Adult immersion test 9.89 ppm 0.456 S 34537543
Rhipicephalus microplus Adult Madhya Pradesh Barwani Adult immersion test 22.93 ppm 1.05 S 37468088
Rhipicephalus microplus Adult Madhya Pradesh Damoh Adult immersion test 59.28 ppm 2.73 I 37468088
Rhipicephalus microplus Adult Madhya Pradesh Indore Adult immersion test 51.8 ppm 2.38 I 37468088
Rhipicephalus microplus Adult Madhya Pradesh Jabalpur Adult immersion test 67.17 ppm 3.09 I 37468088
Rhipicephalus microplus Adult Madhya Pradesh Katni Adult immersion test 72.83 ppm 3.35 I 37468088
Rhipicephalus microplus Adult Madhya Pradesh Khandwa Adult immersion test 67.12 ppm 3.09 I 37468088
Rhipicephalus microplus Adult Madhya Pradesh Mandla Adult immersion test 40.99 ppm 1.89 I 37468088
Rhipicephalus microplus Adult Madhya Pradesh Mandsaur Adult immersion test 27.95 ppm 1.28 S 37468088
Rhipicephalus microplus Adult Madhya Pradesh Narsinghpur Adult immersion test 70.54 ppm 3.25 I 37468088
Rhipicephalus microplus Adult Madhya Pradesh Shajapur Adult immersion test 63.7 ppm 2.98 I 37468088
Rhipicephalus microplus Adult Uttar Pradesh Moradabad Adult immersion test 24.1 ppm 1.33 S 32284118
Rhipicephalus microplus Adult Assam Barpeta Adult immersion test 8.24 ppm 0.38 S 32284118
Rhipicephalus microplus Adult Assam Morigaon Adult immersion test 8.24 ppm 0.38 S 32284118
Rhipicephalus microplus Adult Haryana Kurukshetra Adult immersion test 20 ppm 0.95 S 32284118
Rhipicephalus microplus Adult Haryana Ambala Adult immersion test 84.1 ppm 3.6 I 32284118
Rhipicephalus microplus Adult Haryana Karnal Adult immersion test 55.3 ppm 2.5 I 32284118
Rhipicephalus microplus Adult Uttar Pradesh Lucknow Adult immersion test 20.7 ppm 1.07 S 32284118
Rhipicephalus microplus Adult Uttar Pradesh Kanpur Adult immersion test 19.4 ppm 1.07 S 32284118
Rhipicephalus microplus Adult Uttar Pradesh Amroha Adult immersion test 18.6 ppm 1.02 S 32284118
Rhipicephalus microplus Adult Uttar Pradesh Mathura Adult immersion test 19.8 ppm 0.91 S 31463660
Rhipicephalus microplus Adult Madhya Pradesh Dewas Adult immersion test 47.3 ppm 2.18 I 31463660
Rhipicephalus microplus Adult Madhya Pradesh Mhow Adult immersion test 65.5 ppm 3.02 I 31463660
Rhipicephalus microplus Adult Madhya Pradesh Rewa Adult immersion test 33.2 ppm 1.53 I 31463660
Rhipicephalus microplus Adult Punjab Fatehgarh Sahib Adult immersion test 178.8 ppm 9.88 II 31463660
Rhipicephalus microplus Adult Madhya Pradesh Udaynagar Adult immersion test 42.8 ppm 1.97 I 31463660
Rhipicephalus microplus Larvae Punjab Patiala Larval immersion test 21.38 ppm 6.27 II 29477957
Rhipicephalus microplus Larvae Punjab Rupnagar Larval immersion test 5.63 ppm 1.65 I 29477957
Rhipicephalus microplus Larvae Punjab Sahibzada Ajit Singh Nagar Larval immersion test 14.02 ppm 4.11 I 29477957
Rhipicephalus microplus Larvae Punjab Shaheed Bhagat Singh Nagar Larval immersion test 9.62 ppm 2.82 I 29477957
Rhipicephalus microplus Larvae Punjab Sri Muktsar Sahib Larval immersion test 22.75 ppm 6.67 II 29477957
Rhipicephalus microplus Adult Uttar Pradesh Lucknow Adult immersion test 49.35 ppm 2.27 I 29329620
Rhipicephalus microplus Adult Uttar Pradesh Kanpur Adult immersion test 95.53 ppm 4.41 I 29329620
Rhipicephalus microplus Larvae Punjab Amritsar Larval immersion test 22.41 ppm 6.57 II 29477957
Rhipicephalus microplus Larvae Punjab Barnala Larval immersion test 13.64 ppm 4 I 29477957
Rhipicephalus microplus Larvae Punjab Fatehgarh Sahib Larval immersion test 12.21 ppm 3.58 I 29477957
Rhipicephalus microplus Larvae Punjab Fazilka Larval immersion test 30.95 ppm 9.07 II 29477957
Rhipicephalus microplus Larvae Punjab Jalandhar Larval immersion test 10.61 ppm 3.11 I 29477957
Rhipicephalus microplus Larvae Punjab Kapurthala Larval immersion test 14.86 ppm 4.36 I 29477957
Rhipicephalus microplus Larvae Punjab Ludhiana Larval immersion test 21.43 ppm 6.28 II 29477957
Rhipicephalus microplus Larvae Punjab Mansa Larval immersion test 14.28 ppm 4.18 I 29477957
Rhipicephalus microplus Larvae Punjab Moga Larval immersion test 10.43 ppm 3.06 I 29477957
Rhipicephalus microplus Adult Uttar Pradesh Amroha Adult immersion test 86.66 ppm 3.99 I 29329620
Rhipicephalus microplus Adult Uttar Pradesh Mathura Adult immersion test 51.51 ppm 2.38 I 29329620
Rhipicephalus microplus Adult Punjab Fatehgarh Sahib Adult immersion test 178.8 ppm 8.25 II 29329620
Rhipicephalus microplus Adult Punjab Ludhiana Adult immersion test 101.71 ppm 4.69 I 29329620
Rhipicephalus microplus Adult Bihar Saharsa Adult immersion test 33.8 ppm 1.56 I 29329620
Rhipicephalus microplus Larvae Punjab Bathinda Larval immersion test 25.9 ppm 7.59 II 26404476
Rhipicephalus microplus Larvae Punjab Gurdaspur Larval immersion test 30.19 ppm 8.85 II 26404476
Rhipicephalus microplus Larvae Punjab Hoshiarpur Larval immersion test 22.83 ppm 6.69 II 26404476
Rhipicephalus microplus Larvae Punjab Pathankot Larval immersion test 10.13 ppm 2.97 I 26404476
Rhipicephalus microplus Larvae Jammu and Kashmir Kulgam Larval immersion test 3.41 ppm 1 S 26404476
Rhipicephalus sanguineus Larvae Andhra Pradesh Krishna Vijayawada Larval immersion test 39.6 ppm 3.9 I 34535851
Rhipicephalus sanguineus Larvae Andhra Pradesh Krishna Vijayawada Larval immersion test 48.5 ppm 4.8 I 34535851
Rhipicephalus sanguineus Larvae Andhra Pradesh Krishna Vijayawada Larval immersion test 16.2 ppm 1.6 I 34535851
Rhipicephalus sanguineus Larvae Andhra Pradesh Krishna Machilipatnam Larval immersion test 12 ppm 1.2 S 34535851
Rhipicephalus sanguineus Larvae Andhra Pradesh Krishna Machilipatnam Larval immersion test 11.9 ppm 1.2 S 34535851
Rhipicephalus sanguineus Larvae Andhra Pradesh West Godavari Tanuku Larval immersion test 14.8 ppm 1.5 I 34535851
Rhipicephalus sanguineus Larvae Andhra Pradesh West Godavari Eluru Larval immersion test 12.9 ppm 1.3 S 34535851
Rhipicephalus sanguineus Larvae Andhra Pradesh Vishakapatnam Vishakapatnam Larval immersion test 13.5 ppm 1.3 S 34535851
Rhipicephalus sanguineus Larvae Andhra Pradesh Vishakapatnam Vishakapatnam Larval immersion test 15.2 ppm 1.5 I 34535851
Rhipicephalus sanguineus Larvae Andhra Pradesh Guntur Guntur Larval immersion test 17.5 ppm 1.7 I 34535851
Rhipicephalus sanguineus Larvae Andhra Pradesh Kadapa YSR Kadapa Larval immersion test 11.7 ppm 1.2 S 34535851
Rhipicephalus sanguineus Larvae Andhra Pradesh Anantapur Anantapur Larval immersion test 43.5 ppm 4.3 I 34535851
Rhipicephalus sanguineus Larvae Andhra Pradesh Anantapur Anantapur Larval immersion test 12.6 ppm 1.3 S 34535851
DISCLAIMER

TickMapKB is a database of tick species, their distribution, and associated data, compiled from published literature and publicly available sources. The authors are not liable for any inaccuracies or omissions in this resource. This database is intended to support research on tick ecology and distribution and does not necessarily reflect the views or objectives of the authors’ affiliated institutions or funders.