For more information regarding the endpoints, refer to the 'ToxCast Endpoints' file on the
DOWNLOAD page.
No ToxCast endpoints for intended target type: RNA
ToxCast Endpoints for intended target type: Protein
Assay Name | Tissue | Target Gene ID | Target HGNC Symbol | Target UniProt ID | Response | AC50 value |
---|
ATG_NRF2_ARE_CIS | Liver | 4780 | NFE2L2 | Q16236 | Inhibitory | 26.08 μM |
ATG_PXRE_CIS | Liver | 8856 | NR1I2 | O75469 | Inhibitory | 27.84 μM |
NVS_ENZ_hPDE10 | | 10846 | PDE10A | Q9Y233 | Loss | 46.47 μM |
TOX21_p450_CYP1A2_Antagonist | | 1544 | CYP1A2 | P05177 | Loss | 43.44 μM |
No ToxCast endpoints for intended target type: Molecular Messengers
No ToxCast endpoints for intended target type: Pathway
No ToxCast endpoints for intended target type: Cellular
No ToxCast endpoints for intended target type: Extracellular