For more information regarding the endpoints, refer to the 'ToxCast Endpoints' file on the
DOWNLOAD page.
ToxCast Endpoints for intended target type: RNA
Assay Name | Tissue | Target Gene ID | Target HGNC Symbol | Target UniProt ID | Response | AC50 value |
---|
LTEA_HepaRG_CYP1A1 | Liver | 1543 | CYP1A1 | P04798 | Activatory | 50.00 μM |
ToxCast Endpoints for intended target type: Protein
Assay Name | Tissue | Target Gene ID | Target HGNC Symbol | Target UniProt ID | Response | AC50 value |
---|
ATG_NURR1_TRANS | Liver | 4929 | NR4A2 | P43354 | Gain | 6.74 μM |
ATG_RXRa_TRANS | Liver | 6256 | RXRA | P19793 | Gain | 5.06 μM |
ATG_RXRb_TRANS | Liver | 6257 | RXRB | P28702 | Gain | 1.11 μM |
NVS_ENZ_hIGF1R | | 3480 | IGF1R | P08069 | Loss | 5.18 μM |
No ToxCast endpoints for intended target type: Molecular Messengers
No ToxCast endpoints for intended target type: Pathway
No ToxCast endpoints for intended target type: Cellular
No ToxCast endpoints for intended target type: Extracellular