ToxCast Endpoints
For more information regarding the endpoints, refer to the 'ToxCast Endpoints' file on the DOWNLOAD page.

ToxCast Endpoints for intended target type: RNA
Assay NameTissueTarget Gene IDTarget HGNC SymbolTarget UniProt IDResponseAC50 value
LTEA_HepaRG_ABCC2Liver1244ABCC2Q92887Activatory9.92 μM
LTEA_HepaRG_ABCG2Liver9429ABCG2Q9UNQ0Activatory9.40 μM
LTEA_HepaRG_CYP2B6Liver1555CYP2B6P20813Activatory5.80 μM
LTEA_HepaRG_CYP2C19Liver1557CYP2C19P33261Activatory15.42 μM
LTEA_HepaRG_CYP2C8Liver1558CYP2C8P10632Activatory12.70 μM
LTEA_HepaRG_CYP2C9Liver1559CYP2C9P11712Activatory6.12 μM
LTEA_HepaRG_CYP2E1Liver1571CYP2E1P05181Inhibitory10.06 μM
LTEA_HepaRG_CYP3A4Liver1576CYP3A4P08684Activatory7.10 μM
LTEA_HepaRG_CYP3A7Liver1551CYP3A7P24462Activatory5.99 μM
LTEA_HepaRG_UGT1A1Liver54658UGT1A1P22309Activatory7.77 μM

ToxCast Endpoints for intended target type: Protein
Assay NameTissueTarget Gene IDTarget HGNC SymbolTarget UniProt IDResponseAC50 value
BSK_3C_TissueFactorVascular2152F3P13726Inhibitory3.97 μM
TOX21_p450_CYP1A2_Antagonist1544CYP1A2P05177Loss3.96 μM
TOX21_p450_CYP1A2_Antagonist1544CYP1A2P05177Loss4.06 μM

No ToxCast endpoints for intended target type: Molecular Messengers

No ToxCast endpoints for intended target type: Pathway

No ToxCast endpoints for intended target type: Cellular

No ToxCast endpoints for intended target type: Extracellular
DISCLAIMER

TICToK is a database of tattoo ink chemicals compiled from different regulatory resources. The authors are not liable for any inaccuracies or omissions of any chemicals in this resource. Importantly, our sole goal to build this resource on tattoo ink chemicals is to enable future basic research on this topic, and it does not necessarily reflect the views or objectives of our employers or funders.