4,4'-Diiodobiphenyl
Associated AOPs with Level of Relevance - 1 AOPs with at least 1 KE associated with chemical, where the KE(s) are neither MIE nor AO
| AOP Identifier |
AOP Title |
AO Classification |
OECD Status |
Taxonomic applicability |
Coverage Score
ⓘ
The fraction of KEs within the AOP, that are mapped to the chemical-associated toxicological endpoints.
|
KE Identifier |
KE Name |
| AOP:275 | Histone deacetylase inhibition leads to neural tube defects | Neural tube defect | - | | 0.2 | KE:1239 | Altered, Gene Expression |
| AOP:533 | Retinoic acid receptor antagonism during neurodevelopment leading to impaired learning and memory | Developmental disorder of mental health | - | | 0.17 | KE:1239 | Altered, Gene Expression |
| AOP:535 | Binding and activation of GPER leading to learning and memory impairments | Developmental disorder of mental health | - | Mouse, Human | 0.11 | KE:2233 | Decreased, ERαβ heterodimers |
No associated AOPs with Level of Relevance 2
Associated AOPs with Level of Relevance - 3 AOPs with at least 1 MIE associated with chemical, and no associated AO
| AOP Identifier |
AOP Title |
AO Classification |
OECD Status |
Taxonomic applicability |
Coverage Score
ⓘ
The fraction of KEs within the AOP, that are mapped to the chemical-associated toxicological endpoints.
|
KE Identifier |
KE Name |
| AOP:446 | PM-related Adverse outcome pathway frameworks on various systems | Respiratory system disease | - | | 0.05 | KE:1239 | Altered, Gene Expression |
| AOP:525 | Reduced oligodendrocyte differentiation during neurodevelopment leading to impaired learning and memory | Developmental disorder of mental health | - | | 0.08 | KE:2216 | Binding of antagonist to thyroid hormone receptor |
No associated AOPs with Level of Relevance 5
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