Mitotane


Curated chemical-disease associations from CTD
Disease IDDisease nameReference
MESH:D000303 Adrenal Cortex Diseases PMID:17675396; PMID:3798445
MESH:D000505 Alopecia PMID:3798445
MESH:D001523 Mental Disorders PMID:12015757; PMID:1517795
MESH:D001778 Blood Coagulation Disorders PMID:16822769
MESH:D002493 Central Nervous System Diseases PMID:2954144
MESH:D003967 Diarrhea PMID:12015757; PMID:3798445
MESH:D005076 Exanthema PMID:1517795
MESH:D005221 Fatigue PMID:12015757
MESH:D005767 Gastrointestinal Diseases PMID:1517795
MESH:D006470 Hemorrhage PMID:8453685
MESH:D006937 Hypercholesterolemia PMID:1480741
MESH:D007006 Hypogonadism PMID:3441014
MESH:D007172 Erectile Dysfunction PMID:3441014
MESH:D007565 Jaundice PMID:16822769
MESH:D007806 Language Disorders PMID:1517795
MESH:D008569 Memory Disorders PMID:1517795
MESH:D009325 Nausea PMID:12015757
MESH:D009336 Necrosis PMID:8453685
MESH:D009503 Neutropenia PMID:12015757
MESH:D010523 Peripheral Nervous System Diseases PMID:2954144
MESH:D011559 Pseudotumor Cerebri PMID:2963295
MESH:D014202 Tremor PMID:3798445
MESH:D018908 Muscle Weakness PMID:3798445
MESH:D020879 Neuromuscular Manifestations PMID:1517795
MESH:D047928 Premature Birth PMID:27748297
MESH:D056486 Chemical and Drug Induced Liver Injury PMID:16822769
MESH:D064420 Drug-Related Side Effects and Adverse Reactions PMID:12015757; PMID:17675396; PMID:2954144; PMID:3798445; PMID:8453685

DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.