Aldrin

Target genes for Aldrin is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
AldrinNR1H3ATG_DR4_LXR_CIS_dn
AldrinCCL26BSK_4H_Eotaxin3_down
AldrinCOL3A1BSK_hDFCGF_CollagenIII_down
AldrinCSF1BSK_LPS_MCSF_down
AldrinCSF1BSK_hDFCGF_MCSF_down
AldrinCSF1BSK_CASM3C_MCSF_down
AldrinEGR1ATG_EGR_CIS_up
AldrinESR1ATG_ERE_CIS_up
AldrinESR1ATG_ERa_TRANS_up
AldrinESR2TOX21_ERb_BLA_Antagonist_ratio
AldrinESR2TOX21_ERb_BLA_Agonist_ratio
AldrinESR2OT_ER_ERbERb_1440
AldrinESRRATOX21_PGC_ERR_Antagonist
AldrinESRRATOX21_ERR_Antagonist
AldrinF3BSK_LPS_TissueFactor_down
AldrinF3BSK_3C_TissueFactor_down
AldrinATF6TOX21_ESRE_BLA_ratio
AldrinFOSATG_AP_1_CIS_up
AldrinNR3C1TOX21_GR_BLA_Agonist_ratio
AldrinHIF1ATOX21_HRE_BLA_Agonist_ratio
AldrinHLA-DRABSK_3C_HLADR_down
AldrinHLA-DRABSK_CASM3C_HLADR_down
AldrinHSF1TOX21_HSE_BLA_agonist_ratio
AldrinICAM1BSK_KF3CT_ICAM1_down
AldrinICAM1BSK_3C_ICAM1_down
AldrinIL1ABSK_KF3CT_IL1a_down
AldrinIL1ABSK_LPS_IL1a_down
AldrinCXCL8BSK_SAg_IL8_down
AldrinCXCL8BSK_LPS_IL8_down
AldrinCXCL8BSK_hDFCGF_IL8_down
AldrinCXCL8BSK_CASM3C_IL8_down
AldrinCXCL8BSK_3C_IL8_down
AldrinCXCL10BSK_KF3CT_IP10_down
AldrinCXCL10BSK_hDFCGF_IP10_down
AldrinCXCL10BSK_BE3C_IP10_down
AldrinAROT_AR_ARSRC1_0960
AldrinARACEA_AR_antagonist_80hr
AldrinARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
AldrinAROT_AR_ARSRC1_0480
AldrinJUNATG_AP_1_CIS_up
AldrinJUNTOX21_AP1_BLA_Agonist_ratio
AldrinKDRBSK_4H_VEGFRII_down
AldrinLDLRBSK_CASM3C_LDLR_down
AldrinFOSTOX21_AP1_BLA_Agonist_ratio
AldrinCXCL9BSK_hDFCGF_MIG_down
AldrinCXCL9BSK_3C_MIG_down
AldrinCXCL9BSK_SAg_MIG_down
AldrinCXCL9BSK_CASM3C_MIG_down
AldrinMMP1BSK_BE3C_MMP1_up
AldrinMMP1BSK_hDFCGF_MMP1_down
AldrinMMP9BSK_KF3CT_MMP9_down
AldrinMTF1ATG_MRE_CIS_up
AldrinNFE2L2ATG_NRF2_ARE_CIS_up
AldrinNFKB1ATG_NF_kB_CIS_up
AldrinSERPINE1BSK_hDFCGF_PAI1_down
AldrinSERPINE1BSK_BE3C_PAI1_down
AldrinPGRTOX21_PR_BLA_Antagonist_ratio
AldrinPLAUBSK_KF3CT_uPA_down
AldrinPLAURBSK_4H_uPAR_down
AldrinPLAURBSK_CASM3C_uPAR_down
AldrinPLAURBSK_3C_uPAR_down
AldrinPOU2F1ATG_Oct_MLP_CIS_up
AldrinPPARDTOX21_PPARd_BLA_agonist_ratio
AldrinRARAATG_DR5_CIS_up
AldrinRARBATG_DR5_CIS_up
AldrinRARGATG_DR5_CIS_up
AldrinRARGATG_RARg_TRANS_up
AldrinRORAATG_RORE_CIS_up
AldrinRORBATG_RORE_CIS_up
AldrinRORCATG_RORE_CIS_up
AldrinRXRBATG_RXRb_TRANS_up
AldrinSAA1BSK_CASM3C_SAA_down
AldrinCCL2BSK_CASM3C_MCP1_down
AldrinCCL2BSK_3C_MCP1_down
AldrinCCL2BSK_SAg_MCP1_down
AldrinCCL2BSK_4H_MCP1_down
AldrinCCL2BSK_KF3CT_MCP1_down
AldrinCCL2BSK_LPS_MCP1_down
AldrinSELEBSK_LPS_Eselectin_down
AldrinSELEBSK_SAg_Eselectin_down
AldrinSELEBSK_3C_Eselectin_down
AldrinSELPBSK_4H_Pselectin_down
AldrinSLC5A5NIS_RAIU_inhibition
AldrinTGFB1BSK_KF3CT_TGFb1_down
AldrinTIMP1BSK_hDFCGF_TIMP1_down
AldrinTIMP2BSK_KF3CT_TIMP2_down
AldrinTNFBSK_LPS_TNFa_down
AldrinTP53APR_HepG2_p53Act_72h_up
AldrinTP53APR_HepG2_p53Act_24h_up
AldrinTP53TOX21_p53_BLA_p4_ratio
AldrinTP53TOX21_p53_BLA_p1_ratio
AldrinTSHRTOX21_TSHR_Agonist_ratio
AldrinNR1H2ATG_DR4_LXR_CIS_dn
AldrinVCAM1BSK_3C_VCAM1_down
AldrinVCAM1BSK_LPS_VCAM1_down
AldrinVCAM1BSK_CASM3C_VCAM1_down
AldrinVCAM1BSK_4H_VCAM1_down
AldrinVCAM1BSK_hDFCGF_VCAM1_down
AldrinVDRATG_VDRE_CIS_up
AldrinXBP1ATG_Xbp1_CIS_up
AldrinNR1I2ATG_PXR_TRANS_up
AldrinNR1I2ATG_PXRE_CIS_up
AldrinCD38BSK_SAg_CD38_down
AldrinCD40BSK_SAg_CD40_down
AldrinCD40BSK_LPS_CD40_down
AldrinCD69BSK_SAg_CD69_down
AldrinNR1I3ATG_PBREM_CIS_up
AldrinNR1H4ATG_FXR_TRANS_up
AldrinNR1H4TOX21_FXR_BLA_antagonist_ratio
AldrinNR1H4ATG_IR1_CIS_dn

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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.