Dibutyldichlorotin

Target genes for Dibutyldichlorotin is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
DibutyldichlorotinNR1H3ATG_DR4_LXR_CIS_dn
DibutyldichlorotinCREB3ATG_CRE_CIS_up
DibutyldichlorotinCEBPBATG_C_EBP_CIS_up
DibutyldichlorotinCYP19A1TOX21_Aromatase_Inhibition
DibutyldichlorotinCYP24A1TOX21_VDR_BLA_antagonist_ratio
DibutyldichlorotinEGR1ATG_EGR_CIS_up
DibutyldichlorotinESR1TOX21_ERa_LUC_VM7_Antagonist_0.1nM_E2
DibutyldichlorotinESR1OT_ERa_EREGFP_0120
DibutyldichlorotinESR1ATG_ERE_CIS_up
DibutyldichlorotinESR1TOX21_ERa_BLA_Antagonist_ratio
DibutyldichlorotinESR1TOX21_ERa_LUC_VM7_Antagonist_0.5nM_E2
DibutyldichlorotinESR1OT_ERa_EREGFP_0480
DibutyldichlorotinESR1TOX21_ERa_BLA_Agonist_ratio
DibutyldichlorotinESR1ATG_ERa_TRANS_up
DibutyldichlorotinESR2TOX21_ERb_BLA_Antagonist_ratio
DibutyldichlorotinESRRATOX21_ERR_Antagonist
DibutyldichlorotinESRRATOX21_PGC_ERR_Antagonist
DibutyldichlorotinETS1ATG_Ets_CIS_dn
DibutyldichlorotinATF6TOX21_ESRE_BLA_ratio
DibutyldichlorotinFOXO1ATG_FoxO_CIS_dn
DibutyldichlorotinFOXO3ATG_FoxO_CIS_dn
DibutyldichlorotinGLI1ATG_GLI_CIS_up
DibutyldichlorotinNR3C1TOX21_GR_BLA_Agonist_ratio
DibutyldichlorotinNR3C1TOX21_GR_BLA_Antagonist_ratio
DibutyldichlorotinNR3C1NVS_NR_hGR
DibutyldichlorotinHIF1ATOX21_HRE_BLA_Agonist_ratio
DibutyldichlorotinHIF1AATG_HIF1a_CIS_up
DibutyldichlorotinONECUT1ATG_HNF6_CIS_dn
DibutyldichlorotinHSF1ATG_HSE_CIS_up
DibutyldichlorotinHSF1TOX21_HSE_BLA_agonist_ratio
DibutyldichlorotinIRF1ATG_ISRE_CIS_dn
DibutyldichlorotinARACEA_AR_antagonist_80hr
DibutyldichlorotinARTOX21_AR_LUC_MDAKB2_Antagonist_10nM_R1881
DibutyldichlorotinARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
DibutyldichlorotinAROT_AR_ARSRC1_0960
DibutyldichlorotinARTOX21_AR_BLA_Antagonist_ratio
DibutyldichlorotinARTOX21_AR_BLA_Agonist_ratio
DibutyldichlorotinAROT_AR_ARSRC1_0480
DibutyldichlorotinJUNTOX21_AP1_BLA_Agonist_ratio
DibutyldichlorotinFOSTOX21_AP1_BLA_Agonist_ratio
DibutyldichlorotinSMAD1ATG_BRE_CIS_up
DibutyldichlorotinMTF1ATG_MRE_CIS_up
DibutyldichlorotinMYBATG_Myb_CIS_dn
DibutyldichlorotinMYCATG_Myc_CIS_up
DibutyldichlorotinNFIAATG_NFI_CIS_up
DibutyldichlorotinNFE2L2TOX21_ARE_BLA_agonist_ratio
DibutyldichlorotinNFE2L2ATG_NRF2_ARE_CIS_up
DibutyldichlorotinNFKB1ATG_NF_kB_CIS_dn
DibutyldichlorotinNRF1ATG_NRF1_CIS_up
DibutyldichlorotinPAX6ATG_Pax6_CIS_up
DibutyldichlorotinLEF1ATG_TCF_b_cat_CIS_dn
DibutyldichlorotinPGRTOX21_PR_BLA_Antagonist_ratio
DibutyldichlorotinPOU2F1ATG_Oct_MLP_CIS_up
DibutyldichlorotinPPARAATG_PPARa_TRANS_dn
DibutyldichlorotinPPARAATG_PPRE_CIS_up
DibutyldichlorotinPPARANVS_NR_hPPARa
DibutyldichlorotinPPARDATG_PPRE_CIS_up
DibutyldichlorotinPPARDTOX21_PPARd_BLA_antagonist_ratio
DibutyldichlorotinPPARDTOX21_PPARd_BLA_agonist_ratio
DibutyldichlorotinPPARGATG_PPARg_TRANS_up
DibutyldichlorotinPPARGTOX21_PPARg_BLA_Agonist_ratio
DibutyldichlorotinPPARGTOX21_PPARg_BLA_antagonist_ratio
DibutyldichlorotinPPARGATG_PPRE_CIS_up
DibutyldichlorotinRARAATG_RARa_TRANS_dn
DibutyldichlorotinRARANVS_NR_hRARa_Agonist
DibutyldichlorotinRARGATG_RARg_TRANS_dn
DibutyldichlorotinRORAATG_RORE_CIS_up
DibutyldichlorotinRORBATG_RORE_CIS_up
DibutyldichlorotinRORBATG_RORb_TRANS_dn
DibutyldichlorotinRORCATG_RORE_CIS_up
DibutyldichlorotinSOX1ATG_Sox_CIS_up
DibutyldichlorotinSP1ATG_Sp1_CIS_up
DibutyldichlorotinSREBF1ATG_SREBP_CIS_up
DibutyldichlorotinTCF7ATG_TCF_b_cat_CIS_dn
DibutyldichlorotinTCF7L2ATG_TCF_b_cat_CIS_dn
DibutyldichlorotinTHRAATG_THRa1_TRANS_up
DibutyldichlorotinTP53TOX21_p53_BLA_p5_ratio
DibutyldichlorotinTP53TOX21_p53_BLA_p3_ratio
DibutyldichlorotinTP53TOX21_p53_BLA_p2_ratio
DibutyldichlorotinTP53TOX21_p53_BLA_p1_ratio
DibutyldichlorotinTP53TOX21_p53_BLA_p4_ratio
DibutyldichlorotinNR1H2ATG_DR4_LXR_CIS_dn
DibutyldichlorotinVDRATG_VDRE_CIS_up
DibutyldichlorotinVDRTOX21_VDR_BLA_antagonist_ratio
DibutyldichlorotinXBP1ATG_Xbp1_CIS_up
DibutyldichlorotinTCF7L1ATG_TCF_b_cat_CIS_dn
DibutyldichlorotinNR1I2NVS_NR_hPXR
DibutyldichlorotinNR1I2ATG_PXRE_CIS_dn
DibutyldichlorotinNR1I3TOX21_CAR_Antagonist
DibutyldichlorotinNR1H4ATG_IR1_CIS_dn
DibutyldichlorotinNR1H4TOX21_FXR_BLA_antagonist_ratio

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