Phenylmercuric acetate

Target genes for Phenylmercuric acetate is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
Phenylmercuric acetateHDAC6NVS_ENZ_hHDAC6
Phenylmercuric acetateNR1H3ATG_DR4_LXR_CIS_dn
Phenylmercuric acetateNR1H3ATG_LXRa_TRANS_up
Phenylmercuric acetateCCL26BSK_4H_Eotaxin3_down
Phenylmercuric acetateCREB3ATG_CRE_CIS_up
Phenylmercuric acetateCEBPBATG_C_EBP_CIS_up
Phenylmercuric acetateCHRM1NVS_GPCR_hM1
Phenylmercuric acetateCHRM2NVS_GPCR_hM2
Phenylmercuric acetateCHRM3NVS_GPCR_hM3
Phenylmercuric acetateCHRM4NVS_GPCR_hM4
Phenylmercuric acetateCHRM5NVS_GPCR_hM5
Phenylmercuric acetateLTB4RNVS_GPCR_hLTB4_BLT1
Phenylmercuric acetateCOL3A1BSK_hDFCGF_CollagenIII_down
Phenylmercuric acetateADORA1NVS_GPCR_hAdoRA1
Phenylmercuric acetateADORA2ANVS_GPCR_hAdoRA2a
Phenylmercuric acetateCSF1BSK_LPS_MCSF_down
Phenylmercuric acetateCSF1BSK_CASM3C_MCSF_down
Phenylmercuric acetateCSF1BSK_hDFCGF_MCSF_down
Phenylmercuric acetateADRA2ANVS_GPCR_hAdra2A
Phenylmercuric acetateADRA2CNVS_GPCR_hAdra2C
Phenylmercuric acetateADRB1NVS_GPCR_hAdrb1
Phenylmercuric acetateADRB2NVS_GPCR_hAdrb2
Phenylmercuric acetateCYP1A1NVS_ADME_hCYP1A1
Phenylmercuric acetateCYP1A2NVS_ADME_hCYP1A2
Phenylmercuric acetateADRB3NVS_GPCR_hAdrb3
Phenylmercuric acetateCYP2B6NVS_ADME_hCYP2B6
Phenylmercuric acetateCYP2C19NVS_ADME_hCYP2C19
Phenylmercuric acetateCYP2C9NVS_ADME_hCYP2C9
Phenylmercuric acetateCYP2D6NVS_ADME_hCYP2D6
Phenylmercuric acetateCYP3A4NVS_ADME_hCYP3A4
Phenylmercuric acetateCYP19A1TOX21_Aromatase_Inhibition
Phenylmercuric acetateCYP24A1TOX21_VDR_BLA_antagonist_ratio
Phenylmercuric acetateDRD1NVS_GPCR_hDRD1
Phenylmercuric acetateDRD2NVS_GPCR_hDRD2s
Phenylmercuric acetateDRD4NVS_GPCR_hDRD4.4
Phenylmercuric acetateAGTR1NVS_GPCR_hAT1
Phenylmercuric acetateEDNRANVS_GPCR_hETA
Phenylmercuric acetateEGFRNVS_ENZ_hEGFR
Phenylmercuric acetateEGR1ATG_EGR_CIS_up
Phenylmercuric acetateSLC29A1NVS_TR_hAdoT
Phenylmercuric acetateESR1OT_ERa_EREGFP_0480
Phenylmercuric acetateESR1TOX21_ERa_LUC_VM7_Antagonist_0.1nM_E2
Phenylmercuric acetateESR1TOX21_ERa_LUC_VM7_Antagonist_0.5nM_E2
Phenylmercuric acetateESR1OT_ERa_EREGFP_0120
Phenylmercuric acetateESR1TOX21_ERa_BLA_Antagonist_ratio
Phenylmercuric acetateESR1TOX21_ERa_BLA_Agonist_ratio
Phenylmercuric acetateESR2TOX21_ERb_BLA_Antagonist_ratio
Phenylmercuric acetateESRRATOX21_PGC_ERR_Antagonist
Phenylmercuric acetateESRRATOX21_ERR_Antagonist
Phenylmercuric acetateF3BSK_3C_TissueFactor_down
Phenylmercuric acetateF3BSK_LPS_TissueFactor_down
Phenylmercuric acetateF3BSK_CASM3C_TissueFactor_down
Phenylmercuric acetateFGFR1NVS_ENZ_hFGFR1
Phenylmercuric acetateATF6TOX21_ESRE_BLA_ratio
Phenylmercuric acetateSIRT2NVS_ENZ_hSIRT2
Phenylmercuric acetateSIRT1NVS_ENZ_hSIRT1
Phenylmercuric acetateNR3C1TOX21_GR_BLA_Agonist_ratio
Phenylmercuric acetateNR3C1TOX21_GR_BLA_Antagonist_ratio
Phenylmercuric acetateNR3C1ATG_GRE_CIS_dn
Phenylmercuric acetateHDAC1TOX21_HDAC_Inhibition
Phenylmercuric acetateHIF1AATG_HIF1a_CIS_up
Phenylmercuric acetateHIF1ATOX21_HRE_BLA_Agonist_ratio
Phenylmercuric acetateHLA-DRABSK_CASM3C_HLADR_down
Phenylmercuric acetateHLA-DRABSK_BE3C_HLADR_down
Phenylmercuric acetateHLA-DRABSK_3C_HLADR_down
Phenylmercuric acetateONECUT1ATG_HNF6_CIS_dn
Phenylmercuric acetateHRH1NVS_GPCR_hH1
Phenylmercuric acetateHSF1TOX21_HSE_BLA_agonist_ratio
Phenylmercuric acetateHTR2ANVS_GPCR_h5HT2A
Phenylmercuric acetateHTR5ANVS_GPCR_h5HT5A
Phenylmercuric acetateHTR6NVS_GPCR_h5HT6
Phenylmercuric acetateHTR7NVS_GPCR_h5HT7
Phenylmercuric acetateICAM1BSK_3C_ICAM1_down
Phenylmercuric acetateICAM1BSK_KF3CT_ICAM1_down
Phenylmercuric acetateIL1ABSK_LPS_IL1a_down
Phenylmercuric acetateIL1ABSK_KF3CT_IL1a_down
Phenylmercuric acetateIL1ABSK_BE3C_IL1a_down
Phenylmercuric acetateIL6BSK_CASM3C_IL6_down
Phenylmercuric acetateCXCL8BSK_LPS_IL8_down
Phenylmercuric acetateCXCL8BSK_SAg_IL8_down
Phenylmercuric acetateCXCL8BSK_3C_IL8_down
Phenylmercuric acetateCXCL8BSK_CASM3C_IL8_down
Phenylmercuric acetateCXCL8BSK_hDFCGF_IL8_down
Phenylmercuric acetateCXCL10BSK_hDFCGF_IP10_down
Phenylmercuric acetateCXCL10BSK_KF3CT_IP10_down
Phenylmercuric acetateCXCL10BSK_BE3C_IP10_down
Phenylmercuric acetateARACEA_AR_antagonist_80hr
Phenylmercuric acetateARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
Phenylmercuric acetateAROT_AR_ARSRC1_0480
Phenylmercuric acetateARTOX21_AR_BLA_Antagonist_ratio
Phenylmercuric acetateARTOX21_AR_BLA_Agonist_ratio
Phenylmercuric acetateARTOX21_AR_LUC_MDAKB2_Antagonist_10nM_R1881
Phenylmercuric acetateARNVS_NR_hAR
Phenylmercuric acetateAROT_AR_ARSRC1_0960
Phenylmercuric acetateJUNTOX21_AP1_BLA_Agonist_ratio
Phenylmercuric acetateLDLRBSK_CASM3C_LDLR_down
Phenylmercuric acetateFOSTOX21_AP1_BLA_Agonist_ratio
Phenylmercuric acetateCXCL9BSK_CASM3C_MIG_down
Phenylmercuric acetateCXCL9BSK_BE3C_MIG_down
Phenylmercuric acetateCXCL9BSK_hDFCGF_MIG_down
Phenylmercuric acetateCXCL9BSK_3C_MIG_down
Phenylmercuric acetateCXCL9BSK_SAg_MIG_down
Phenylmercuric acetateACHENVS_ENZ_hAChE
Phenylmercuric acetateMMP1BSK_BE3C_MMP1_down
Phenylmercuric acetateMMP1BSK_hDFCGF_MMP1_down
Phenylmercuric acetateMMP1NVS_ENZ_hMMP1
Phenylmercuric acetateMMP9BSK_KF3CT_MMP9_down
Phenylmercuric acetateMTF1ATG_MRE_CIS_up
Phenylmercuric acetateNFIAATG_NFI_CIS_up
Phenylmercuric acetateNFE2L2ATG_NRF2_ARE_CIS_up
Phenylmercuric acetateNFE2L2TOX21_ARE_BLA_agonist_ratio
Phenylmercuric acetateNFKB1TOX21_NFkB_BLA_agonist_ratio
Phenylmercuric acetateNPY1RNVS_GPCR_hNPY1
Phenylmercuric acetateNPY2RNVS_GPCR_hNPY2
Phenylmercuric acetateOPRD1NVS_GPCR_hOpiate_D1
Phenylmercuric acetateOPRL1NVS_GPCR_hORL1
Phenylmercuric acetateOPRM1NVS_GPCR_hOpiate_mu
Phenylmercuric acetateP2RY1NVS_GPCR_hPY2
Phenylmercuric acetateSERPINE1BSK_hDFCGF_PAI1_down
Phenylmercuric acetateSERPINE1BSK_BE3C_PAI1_down
Phenylmercuric acetatePGRTOX21_PR_BLA_Antagonist_ratio
Phenylmercuric acetatePLATBSK_BE3C_tPA_down
Phenylmercuric acetatePLAUBSK_BE3C_uPA_down
Phenylmercuric acetatePLAUBSK_KF3CT_uPA_down
Phenylmercuric acetatePLAURBSK_4H_uPAR_down
Phenylmercuric acetatePLAURBSK_3C_uPAR_down
Phenylmercuric acetatePLAURBSK_CASM3C_uPAR_down
Phenylmercuric acetatePLAURBSK_BE3C_uPAR_down
Phenylmercuric acetatePOU2F1ATG_Oct_MLP_CIS_up
Phenylmercuric acetatePPARDTOX21_PPARd_BLA_antagonist_ratio
Phenylmercuric acetatePPARDTOX21_PPARd_BLA_agonist_ratio
Phenylmercuric acetatePPARGTOX21_PPARg_BLA_Agonist_ratio
Phenylmercuric acetatePPARGTOX21_PPARg_BLA_antagonist_ratio
Phenylmercuric acetatePRKAA1NVS_ENZ_hAMPKa1
Phenylmercuric acetatePTGER2BSK_LPS_PGE2_down
Phenylmercuric acetatePTPN1NVS_ENZ_hPTPN1
Phenylmercuric acetatePTPN9NVS_ENZ_hPTPN9
Phenylmercuric acetatePTPN12NVS_ENZ_hPTPN12
Phenylmercuric acetatePTPN13NVS_ENZ_hPTPN13
Phenylmercuric acetateRARAATG_DR5_CIS_up
Phenylmercuric acetateRARBATG_DR5_CIS_up
Phenylmercuric acetateRARGATG_DR5_CIS_up
Phenylmercuric acetateRORAATG_RORE_CIS_up
Phenylmercuric acetateRORBATG_RORE_CIS_up
Phenylmercuric acetateRORCATG_RORE_CIS_up
Phenylmercuric acetateRXRAATG_RXRa_TRANS_dn
Phenylmercuric acetateRXRAOT_NURR1_NURR1RXRa_0480
Phenylmercuric acetateRXRAOT_NURR1_NURR1RXRa_1440
Phenylmercuric acetateRXRBATG_RXRb_TRANS_up
Phenylmercuric acetateSAA1BSK_CASM3C_SAA_down
Phenylmercuric acetateCCL2BSK_4H_MCP1_down
Phenylmercuric acetateCCL2BSK_CASM3C_MCP1_down
Phenylmercuric acetateCCL2BSK_3C_MCP1_down
Phenylmercuric acetateCCL2BSK_LPS_MCP1_down
Phenylmercuric acetateCCL2BSK_KF3CT_MCP1_down
Phenylmercuric acetateCCL2BSK_SAg_MCP1_down
Phenylmercuric acetateSELEBSK_3C_Eselectin_down
Phenylmercuric acetateSELEBSK_SAg_Eselectin_down
Phenylmercuric acetateSELEBSK_LPS_Eselectin_down
Phenylmercuric acetateSELPBSK_4H_Pselectin_down
Phenylmercuric acetateSLC5A5NIS_RAIU_inhibition
Phenylmercuric acetateSLC6A2NVS_TR_hNET
Phenylmercuric acetateSLC6A3NVS_TR_hDAT
Phenylmercuric acetateCYP4F12NVS_ADME_hCYP4F12
Phenylmercuric acetateSP1ATG_Sp1_CIS_up
Phenylmercuric acetateTACR2NVS_GPCR_hNK2
Phenylmercuric acetateTBXA2RNVS_GPCR_hTXA2
Phenylmercuric acetateTFAP2AATG_AP_2_CIS_dn
Phenylmercuric acetateTFAP2BATG_AP_2_CIS_dn
Phenylmercuric acetateTGFB1BSK_KF3CT_TGFb1_down
Phenylmercuric acetateTGFB1BSK_BE3C_TGFb1_down
Phenylmercuric acetateTHBDBSK_3C_Thrombomodulin_up
Phenylmercuric acetateTIMP1BSK_hDFCGF_TIMP1_down
Phenylmercuric acetateTIMP2BSK_KF3CT_TIMP2_down
Phenylmercuric acetateTNFBSK_LPS_TNFa_down
Phenylmercuric acetateTP53APR_HepG2_p53Act_72h_up
Phenylmercuric acetateTP53TOX21_p53_BLA_p3_ratio
Phenylmercuric acetateTP53TOX21_p53_BLA_p1_ratio
Phenylmercuric acetateTP53TOX21_p53_BLA_p5_ratio
Phenylmercuric acetateTP53TOX21_p53_BLA_p4_ratio
Phenylmercuric acetateTP53ATG_p53_CIS_dn
Phenylmercuric acetateTP53TOX21_p53_BLA_p2_ratio
Phenylmercuric acetateTP53APR_HepG2_p53Act_24h_up
Phenylmercuric acetateTSHRTOX21_TSHR_Antagonist_ratio
Phenylmercuric acetateTSHRTOX21_TSHR_wt_ratio
Phenylmercuric acetateTSHRTOX21_TSHR_Agonist_ratio
Phenylmercuric acetateNR1H2ATG_DR4_LXR_CIS_dn
Phenylmercuric acetateUSF1ATG_E_Box_CIS_dn
Phenylmercuric acetateVCAM1BSK_CASM3C_VCAM1_down
Phenylmercuric acetateVCAM1BSK_hDFCGF_VCAM1_down
Phenylmercuric acetateVCAM1BSK_LPS_VCAM1_down
Phenylmercuric acetateVCAM1BSK_4H_VCAM1_down
Phenylmercuric acetateVCAM1BSK_3C_VCAM1_down
Phenylmercuric acetateVDRTOX21_VDR_BLA_antagonist_ratio
Phenylmercuric acetateVDRATG_VDRE_CIS_up
Phenylmercuric acetateXBP1ATG_Xbp1_CIS_up
Phenylmercuric acetateCASP3NVS_ENZ_hCASP3
Phenylmercuric acetateTFAP2DATG_AP_2_CIS_dn
Phenylmercuric acetateCASP5NVS_ENZ_hCASP5
Phenylmercuric acetateCASP8NVS_ENZ_hCASP8
Phenylmercuric acetatePDE5ANVS_ENZ_hPDE5
Phenylmercuric acetateHDAC3NVS_ENZ_hHDAC3
Phenylmercuric acetateNR1I2ATG_PXRE_CIS_dn
Phenylmercuric acetateNR1I2NVS_NR_hPXR
Phenylmercuric acetateCD38BSK_SAg_CD38_down
Phenylmercuric acetateCD40BSK_LPS_CD40_down
Phenylmercuric acetateCD40BSK_SAg_CD40_down
Phenylmercuric acetateCD69BSK_SAg_CD69_down
Phenylmercuric acetateNR1I3TOX21_CAR_Antagonist
Phenylmercuric acetateNR1H4OT_FXR_FXRSRC1_1440
Phenylmercuric acetateNR1H4OT_FXR_FXRSRC1_0480
Phenylmercuric acetateNR1H4TOX21_FXR_BLA_agonist_ratio
Phenylmercuric acetateNR1H4TOX21_FXR_BLA_antagonist_ratio

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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.