Captafol

Target genes for Captafol is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
CaptafolCCL26BSK_4H_Eotaxin3_down
CaptafolCOL3A1BSK_hDFCGF_CollagenIII_down
CaptafolCSF1BSK_LPS_MCSF_down
CaptafolCSF1BSK_hDFCGF_MCSF_down
CaptafolCSF1BSK_CASM3C_MCSF_down
CaptafolCYP1A1CLD_CYP1A1_24hr
CaptafolCYP2A6NVS_ADME_hCYP2A6
CaptafolCYP2C8NVS_ADME_hCYP2C8
CaptafolCYP2C18NVS_ADME_hCYP2C18
CaptafolCYP19A1TOX21_Aromatase_Inhibition
CaptafolCYP24A1TOX21_VDR_BLA_antagonist_ratio
CaptafolDIO1NHEERL_MED_hDIO1_dn
CaptafolDRD1NVS_GPCR_hDRD1
CaptafolEGFRBSK_hDFCGF_EGFR_up
CaptafolESR1OT_ER_ERaERa_1440
CaptafolESR1TOX21_ERa_LUC_VM7_Agonist
CaptafolESR1TOX21_ERa_LUC_VM7_Antagonist_0.5nM_E2
CaptafolESR1TOX21_ERa_LUC_VM7_Antagonist_0.1nM_E2
CaptafolESR1TOX21_ERa_BLA_Antagonist_ratio
CaptafolESR2TOX21_ERb_BLA_Antagonist_ratio
CaptafolESRRATOX21_ERR_Antagonist
CaptafolESRRATOX21_PGC_ERR_Antagonist
CaptafolF3BSK_3C_TissueFactor_down
CaptafolF3BSK_LPS_TissueFactor_down
CaptafolATF6TOX21_ESRE_BLA_ratio
CaptafolNR3C1TOX21_GR_BLA_Antagonist_ratio
CaptafolHIF1ATOX21_HRE_BLA_Agonist_ratio
CaptafolHLA-DRABSK_3C_HLADR_down
CaptafolHLA-DRABSK_CASM3C_HLADR_down
CaptafolHLA-DRABSK_BE3C_HLADR_down
CaptafolHSF1TOX21_HSE_BLA_agonist_ratio
CaptafolICAM1BSK_KF3CT_ICAM1_down
CaptafolICAM1BSK_3C_ICAM1_down
CaptafolIL1ABSK_LPS_IL1a_down
CaptafolIL1ABSK_BE3C_IL1a_down
CaptafolIL1ABSK_KF3CT_IL1a_down
CaptafolIL6BSK_CASM3C_IL6_down
CaptafolCXCL8BSK_SAg_IL8_down
CaptafolCXCL8BSK_CASM3C_IL8_down
CaptafolCXCL8BSK_LPS_IL8_down
CaptafolCXCL8BSK_3C_IL8_down
CaptafolCXCL8BSK_hDFCGF_IL8_down
CaptafolCXCL10BSK_KF3CT_IP10_down
CaptafolCXCL10BSK_hDFCGF_IP10_down
CaptafolCXCL10BSK_BE3C_IP10_down
CaptafolARTOX21_AR_BLA_Antagonist_ratio
CaptafolAROT_AR_ARSRC1_0480
CaptafolARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
CaptafolARTOX21_AR_LUC_MDAKB2_Antagonist_10nM_R1881
CaptafolAROT_AR_ARSRC1_0960
CaptafolARACEA_AR_antagonist_80hr
CaptafolARTOX21_AR_BLA_Agonist_ratio
CaptafolJUNTOX21_AP1_BLA_Agonist_ratio
CaptafolKDRBSK_4H_VEGFRII_down
CaptafolFOSTOX21_AP1_BLA_Agonist_ratio
CaptafolCXCL9BSK_SAg_MIG_down
CaptafolCXCL9BSK_BE3C_MIG_down
CaptafolCXCL9BSK_hDFCGF_MIG_down
CaptafolCXCL9BSK_3C_MIG_down
CaptafolCXCL9BSK_CASM3C_MIG_down
CaptafolMMP1BSK_BE3C_MMP1_down
CaptafolMMP1BSK_hDFCGF_MMP1_down
CaptafolMMP9BSK_KF3CT_MMP9_down
CaptafolNFE2L2TOX21_ARE_BLA_agonist_ratio
CaptafolOPRM1NVS_GPCR_hOpiate_mu
CaptafolSERPINE1BSK_hDFCGF_PAI1_down
CaptafolSERPINE1BSK_BE3C_PAI1_down
CaptafolPGRTOX21_PR_BLA_Antagonist_ratio
CaptafolPLATBSK_BE3C_tPA_down
CaptafolPLAUBSK_KF3CT_uPA_down
CaptafolPLAUBSK_BE3C_uPA_down
CaptafolPLAURBSK_3C_uPAR_down
CaptafolPLAURBSK_CASM3C_uPAR_down
CaptafolPLAURBSK_4H_uPAR_down
CaptafolPPARDTOX21_PPARd_BLA_antagonist_ratio
CaptafolPPARGTOX21_PPARg_BLA_antagonist_ratio
CaptafolPTGER2BSK_LPS_PGE2_down
CaptafolRXRAOT_NURR1_NURR1RXRa_1440
CaptafolSAA1BSK_CASM3C_SAA_down
CaptafolCCL2BSK_SAg_MCP1_down
CaptafolCCL2BSK_KF3CT_MCP1_down
CaptafolCCL2BSK_4H_MCP1_down
CaptafolCCL2BSK_CASM3C_MCP1_down
CaptafolCCL2BSK_3C_MCP1_down
CaptafolCCL2BSK_LPS_MCP1_down
CaptafolSELEBSK_SAg_Eselectin_down
CaptafolSELEBSK_LPS_Eselectin_down
CaptafolSELEBSK_3C_Eselectin_down
CaptafolSELPBSK_4H_Pselectin_down
CaptafolSLC5A5NIS_RAIU_inhibition
CaptafolCYP4F12NVS_ADME_hCYP4F12
CaptafolTGFB1BSK_BE3C_TGFb1_down
CaptafolTGFB1BSK_KF3CT_TGFb1_down
CaptafolTHBDBSK_CASM3C_Thrombomodulin_down
CaptafolTIMP1BSK_hDFCGF_TIMP1_down
CaptafolTIMP2BSK_KF3CT_TIMP2_down
CaptafolTNFBSK_LPS_TNFa_down
CaptafolTP53TOX21_p53_BLA_p3_ratio
CaptafolTP53TOX21_p53_BLA_p4_ratio
CaptafolTP53APR_HepG2_p53Act_24h_up
CaptafolTP53TOX21_p53_BLA_p1_ratio
CaptafolTP53TOX21_p53_BLA_p2_ratio
CaptafolTP53TOX21_p53_BLA_p5_ratio
CaptafolTSHRTOX21_TSHR_Agonist_ratio
CaptafolTSHRTOX21_TSHR_Antagonist_ratio
CaptafolVCAM1BSK_CASM3C_VCAM1_down
CaptafolVCAM1BSK_LPS_VCAM1_down
CaptafolVCAM1BSK_hDFCGF_VCAM1_down
CaptafolVCAM1BSK_3C_VCAM1_down
CaptafolVCAM1BSK_4H_VCAM1_down
CaptafolVDRTOX21_VDR_BLA_antagonist_ratio
CaptafolABCB11CLD_ABCB11_6hr
CaptafolABCB11CLD_ABCB11_24hr
CaptafolNR1I2ATG_PXRE_CIS_up
CaptafolCD38BSK_SAg_CD38_down
CaptafolCD40BSK_LPS_CD40_down
CaptafolCD40BSK_SAg_CD40_down
CaptafolCD69BSK_SAg_CD69_down
CaptafolNR1I3TOX21_CAR_Antagonist
CaptafolNR1H4TOX21_FXR_BLA_antagonist_ratio

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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.