Alachlor

Target genes for Alachlor is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
AlachlorNR1H3ATG_DR4_LXR_CIS_dn
AlachlorCCL26BSK_4H_Eotaxin3_down
AlachlorCREB3ATG_CRE_CIS_up
AlachlorCEBPBATG_C_EBP_CIS_up
AlachlorCOL3A1BSK_hDFCGF_CollagenIII_down
AlachlorCSF1BSK_hDFCGF_MCSF_down
AlachlorCSF1BSK_LPS_MCSF_down
AlachlorCYP1A1CLD_CYP1A1_48hr
AlachlorCYP2B6CLD_CYP2B6_48hr
AlachlorCYP2B6NVS_ADME_hCYP2B6
AlachlorCYP2B6CLD_CYP2B6_6hr
AlachlorCYP2B6CLD_CYP2B6_24hr
AlachlorCYP2C19NVS_ADME_hCYP2C19
AlachlorCYP3A4CLD_CYP3A4_24hr
AlachlorCYP3A4CLD_CYP3A4_6hr
AlachlorCYP19A1TOX21_Aromatase_Inhibition
AlachlorESR1TOX21_ERa_BLA_Antagonist_ratio
AlachlorESR1TOX21_ERa_LUC_VM7_Antagonist_0.1nM_E2
AlachlorESR2TOX21_ERb_BLA_Antagonist_ratio
AlachlorESRRATOX21_PGC_ERR_Antagonist
AlachlorESRRATOX21_ERR_Antagonist
AlachlorFOSATG_AP_1_CIS_up
AlachlorGSTA2CLD_GSTA2_48hr
AlachlorHLA-DRABSK_BE3C_HLADR_down
AlachlorHLA-DRABSK_3C_HLADR_down
AlachlorIL1ABSK_LPS_IL1a_up
AlachlorCXCL8BSK_SAg_IL8_down
AlachlorCXCL10BSK_BE3C_IP10_down
AlachlorCXCL10BSK_hDFCGF_IP10_down
AlachlorARTOX21_AR_LUC_MDAKB2_Antagonist_10nM_R1881
AlachlorARACEA_AR_antagonist_80hr
AlachlorARTOX21_AR_BLA_Antagonist_ratio
AlachlorARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
AlachlorAROT_AR_ARSRC1_0960
AlachlorJUNATG_AP_1_CIS_up
AlachlorSMAD1ATG_BRE_CIS_up
AlachlorCXCL9BSK_SAg_MIG_down
AlachlorCXCL9BSK_hDFCGF_MIG_down
AlachlorMMP9BSK_KF3CT_MMP9_down
AlachlorMYCATG_Myc_CIS_up
AlachlorNFIAATG_NFI_CIS_up
AlachlorNFE2L2TOX21_ARE_BLA_agonist_ratio
AlachlorNFE2L2ATG_NRF2_ARE_CIS_up
AlachlorNFKB1ATG_NF_kB_CIS_up
AlachlorOPRM1NVS_GPCR_hOpiate_mu
AlachlorPGRTOX21_PR_BLA_Antagonist_ratio
AlachlorABCB1CLD_ABCB1_48hr
AlachlorPLAURBSK_BE3C_uPAR_up
AlachlorPOU2F1ATG_Oct_MLP_CIS_up
AlachlorPPARDTOX21_PPARd_BLA_antagonist_ratio
AlachlorPPARGATG_PPARg_TRANS_up
AlachlorPPARGNVS_NR_hPPARg
AlachlorPPARGTOX21_PPARg_BLA_antagonist_ratio
AlachlorRXRAOT_NURR1_NURR1RXRa_1440
AlachlorCCL2BSK_LPS_MCP1_down
AlachlorCCL2BSK_3C_MCP1_down
AlachlorCCL2BSK_4H_MCP1_down
AlachlorCCL2BSK_SAg_MCP1_down
AlachlorSELEBSK_SAg_Eselectin_down
AlachlorSELEBSK_3C_Eselectin_down
AlachlorSELEBSK_LPS_Eselectin_down
AlachlorSELPBSK_4H_Pselectin_down
AlachlorSP1ATG_Sp1_CIS_up
AlachlorTSPONVS_MP_hPBR
AlachlorTNFBSK_LPS_TNFa_up
AlachlorTP53APR_HepG2_p53Act_24h_up
AlachlorTSHRTOX21_TSHR_Agonist_ratio
AlachlorNR1H2ATG_DR4_LXR_CIS_dn
AlachlorVCAM1BSK_3C_VCAM1_down
AlachlorVCAM1BSK_LPS_VCAM1_down
AlachlorVCAM1BSK_4H_VCAM1_down
AlachlorVCAM1BSK_hDFCGF_VCAM1_down
AlachlorVDRATG_VDRE_CIS_up
AlachlorNR1I2ATG_PXR_TRANS_up
AlachlorNR1I2ATG_PXRE_CIS_up
AlachlorABCG2CLD_ABCG2_48hr
AlachlorCD38BSK_SAg_CD38_down
AlachlorCD40BSK_LPS_CD40_down
AlachlorCD40BSK_SAg_CD40_down
AlachlorCD69BSK_SAg_CD69_down
AlachlorNR1I3TOX21_CAR_Agonist
AlachlorNR1I3NVS_NR_hCAR_Antagonist

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