Mercuric chloride

Target genes for Mercuric chloride is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
Mercuric chlorideNR1H3ATG_DR4_LXR_CIS_dn
Mercuric chlorideCCL26BSK_4H_Eotaxin3_down
Mercuric chlorideCHRM1NVS_GPCR_hM1
Mercuric chlorideCHRM2NVS_GPCR_hM2
Mercuric chlorideCHRM3NVS_GPCR_hM3
Mercuric chlorideCHRM4NVS_GPCR_hM4
Mercuric chlorideCHRM5NVS_GPCR_hM5
Mercuric chlorideCOL3A1BSK_hDFCGF_CollagenIII_down
Mercuric chlorideADORA2ANVS_GPCR_hAdoRA2a
Mercuric chlorideCSF1BSK_hDFCGF_MCSF_down
Mercuric chlorideCSF1BSK_LPS_MCSF_down
Mercuric chlorideCSF1BSK_CASM3C_MCSF_down
Mercuric chlorideADRA2ANVS_GPCR_hAdra2A
Mercuric chlorideADRA2CNVS_GPCR_hAdra2C
Mercuric chlorideADRB1NVS_GPCR_hAdrb1
Mercuric chlorideADRB2NVS_GPCR_hAdrb2
Mercuric chlorideCYP1A1NVS_ADME_hCYP1A1
Mercuric chlorideCYP1A2NVS_ADME_hCYP1A2
Mercuric chlorideCYP2A6NVS_ADME_hCYP2A6
Mercuric chlorideCYP2B6NVS_ADME_hCYP2B6
Mercuric chlorideCYP2C19NVS_ADME_hCYP2C19
Mercuric chlorideCYP2C9NVS_ADME_hCYP2C9
Mercuric chlorideCYP2D6NVS_ADME_hCYP2D6
Mercuric chlorideCYP3A4NVS_ADME_hCYP3A4
Mercuric chlorideCYP19A1TOX21_Aromatase_Inhibition
Mercuric chlorideCYP24A1TOX21_VDR_BLA_antagonist_ratio
Mercuric chlorideDRD1NVS_GPCR_hDRD1
Mercuric chlorideDRD2NVS_GPCR_hDRD2s
Mercuric chlorideDRD4NVS_GPCR_hDRD4.4
Mercuric chlorideAGTR1NVS_GPCR_hAT1
Mercuric chlorideEDNRANVS_GPCR_hETA
Mercuric chlorideEDNRBNVS_GPCR_hETB
Mercuric chlorideSLC29A1NVS_TR_hAdoT
Mercuric chlorideESR1OT_ERa_EREGFP_0480
Mercuric chlorideESR1OT_ERa_EREGFP_0120
Mercuric chlorideESR1TOX21_ERa_LUC_VM7_Antagonist_0.1nM_E2
Mercuric chlorideESR1TOX21_ERa_BLA_Antagonist_ratio
Mercuric chlorideESR2TOX21_ERb_BLA_Antagonist_ratio
Mercuric chlorideESRRATOX21_PGC_ERR_Antagonist
Mercuric chlorideESRRATOX21_ERR_Antagonist
Mercuric chlorideF3BSK_3C_TissueFactor_down
Mercuric chlorideF3BSK_CASM3C_TissueFactor_down
Mercuric chlorideATF6TOX21_ESRE_BLA_ratio
Mercuric chlorideNR3C1TOX21_GR_BLA_Agonist_ratio
Mercuric chlorideNR3C1TOX21_GR_BLA_Antagonist_ratio
Mercuric chlorideNR3C1NVS_NR_hGR
Mercuric chlorideHDAC1TOX21_HDAC_Inhibition
Mercuric chlorideHIF1ATOX21_HRE_BLA_Agonist_ratio
Mercuric chlorideHIF1AATG_HIF1a_CIS_dn
Mercuric chlorideHLA-DRABSK_BE3C_HLADR_down
Mercuric chlorideHLA-DRABSK_CASM3C_HLADR_down
Mercuric chlorideHLA-DRABSK_3C_HLADR_down
Mercuric chlorideHRH1NVS_GPCR_hH1
Mercuric chlorideHSF1TOX21_HSE_BLA_agonist_ratio
Mercuric chlorideHTR5ANVS_GPCR_h5HT5A
Mercuric chlorideHTR6NVS_GPCR_h5HT6
Mercuric chlorideHTR7NVS_GPCR_h5HT7
Mercuric chlorideICAM1BSK_KF3CT_ICAM1_down
Mercuric chlorideIL1ABSK_BE3C_IL1a_down
Mercuric chlorideIL1ABSK_LPS_IL1a_down
Mercuric chlorideIL1ABSK_KF3CT_IL1a_down
Mercuric chlorideIL6BSK_CASM3C_IL6_down
Mercuric chlorideCXCL8BSK_CASM3C_IL8_down
Mercuric chlorideCXCL8BSK_3C_IL8_down
Mercuric chlorideCXCL8BSK_LPS_IL8_down
Mercuric chlorideCXCL8BSK_hDFCGF_IL8_down
Mercuric chlorideCXCL10BSK_KF3CT_IP10_down
Mercuric chlorideCXCL10BSK_hDFCGF_IP10_down
Mercuric chlorideCXCL10BSK_BE3C_IP10_down
Mercuric chlorideARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
Mercuric chlorideARTOX21_AR_BLA_Antagonist_ratio
Mercuric chlorideARTOX21_AR_BLA_Agonist_ratio
Mercuric chlorideARTOX21_AR_LUC_MDAKB2_Antagonist_10nM_R1881
Mercuric chlorideAROT_AR_ARSRC1_0960
Mercuric chlorideARACEA_AR_antagonist_80hr
Mercuric chlorideAROT_AR_ARSRC1_0480
Mercuric chlorideJUNTOX21_AP1_BLA_Agonist_ratio
Mercuric chlorideLDLRBSK_CASM3C_LDLR_down
Mercuric chlorideFOSTOX21_AP1_BLA_Agonist_ratio
Mercuric chlorideCXCL9BSK_hDFCGF_MIG_down
Mercuric chlorideCXCL9BSK_CASM3C_MIG_down
Mercuric chlorideCXCL9BSK_BE3C_MIG_down
Mercuric chlorideCXCL9BSK_3C_MIG_down
Mercuric chlorideACHENVS_ENZ_hAChE
Mercuric chlorideMMP1BSK_BE3C_MMP1_down
Mercuric chlorideMMP1BSK_hDFCGF_MMP1_down
Mercuric chlorideMMP9BSK_KF3CT_MMP9_down
Mercuric chlorideNFE2L2ATG_NRF2_ARE_CIS_up
Mercuric chlorideNFE2L2TOX21_ARE_BLA_agonist_ratio
Mercuric chlorideNFKB1TOX21_NFkB_BLA_agonist_ratio
Mercuric chlorideNPY1RNVS_GPCR_hNPY1
Mercuric chlorideNPY2RNVS_GPCR_hNPY2
Mercuric chlorideOPRD1NVS_GPCR_hOpiate_D1
Mercuric chlorideOPRL1NVS_GPCR_hORL1
Mercuric chlorideOPRM1NVS_GPCR_hOpiate_mu
Mercuric chlorideSERPINE1BSK_BE3C_PAI1_down
Mercuric chlorideSERPINE1BSK_hDFCGF_PAI1_down
Mercuric chloridePGRTOX21_PR_BLA_Antagonist_ratio
Mercuric chloridePLATBSK_BE3C_tPA_down
Mercuric chloridePLAUBSK_KF3CT_uPA_down
Mercuric chloridePLAUBSK_BE3C_uPA_down
Mercuric chloridePLAURBSK_4H_uPAR_down
Mercuric chloridePLAURBSK_3C_uPAR_down
Mercuric chloridePLAURBSK_CASM3C_uPAR_down
Mercuric chloridePLAURBSK_BE3C_uPAR_down
Mercuric chloridePPARDTOX21_PPARd_BLA_antagonist_ratio
Mercuric chloridePPARDTOX21_PPARd_BLA_agonist_ratio
Mercuric chloridePPARGTOX21_PPARg_BLA_Agonist_ratio
Mercuric chlorideBCHENVS_ENZ_hES
Mercuric chlorideRXRAOT_NURR1_NURR1RXRa_1440
Mercuric chlorideSAA1BSK_CASM3C_SAA_down
Mercuric chlorideCCL2BSK_4H_MCP1_down
Mercuric chlorideCCL2BSK_KF3CT_MCP1_down
Mercuric chlorideCCL2BSK_CASM3C_MCP1_down
Mercuric chlorideSELEBSK_3C_Eselectin_down
Mercuric chlorideSELEBSK_LPS_Eselectin_down
Mercuric chlorideSELEBSK_SAg_Eselectin_down
Mercuric chlorideSELPBSK_4H_Pselectin_down
Mercuric chlorideSLC5A5NIS_RAIU_inhibition
Mercuric chlorideSLC6A2NVS_TR_hNET
Mercuric chlorideSLC6A3NVS_TR_hDAT
Mercuric chlorideSREBF1ATG_SREBP_CIS_dn
Mercuric chlorideTACR2NVS_GPCR_hNK2
Mercuric chlorideTBXA2RNVS_GPCR_hTXA2
Mercuric chlorideTGFB1BSK_KF3CT_TGFb1_down
Mercuric chlorideTGFB1BSK_BE3C_TGFb1_down
Mercuric chlorideTHBDBSK_3C_Thrombomodulin_up
Mercuric chlorideTHBDBSK_CASM3C_Thrombomodulin_up
Mercuric chlorideTIMP1BSK_hDFCGF_TIMP1_down
Mercuric chlorideTIMP2BSK_KF3CT_TIMP2_down
Mercuric chlorideTNFBSK_LPS_TNFa_down
Mercuric chlorideTP53TOX21_p53_BLA_p3_ratio
Mercuric chlorideTP53ATG_p53_CIS_dn
Mercuric chlorideTP53TOX21_p53_BLA_p2_ratio
Mercuric chlorideTP53TOX21_p53_BLA_p4_ratio
Mercuric chlorideTP53APR_HepG2_p53Act_24h_up
Mercuric chlorideTP53TOX21_p53_BLA_p1_ratio
Mercuric chlorideTP53TOX21_p53_BLA_p5_ratio
Mercuric chlorideTSHRTOX21_TSHR_wt_ratio
Mercuric chlorideTSHRTOX21_TSHR_Antagonist_ratio
Mercuric chlorideTSHRTOX21_TSHR_Agonist_ratio
Mercuric chlorideC5AR1NVS_GPCR_hC5a
Mercuric chlorideNR1H2ATG_DR4_LXR_CIS_dn
Mercuric chlorideVCAM1BSK_4H_VCAM1_down
Mercuric chlorideVCAM1BSK_hDFCGF_VCAM1_down
Mercuric chlorideVCAM1BSK_LPS_VCAM1_down
Mercuric chlorideVCAM1BSK_CASM3C_VCAM1_down
Mercuric chlorideVCAM1BSK_3C_VCAM1_down
Mercuric chlorideVDRTOX21_VDR_BLA_antagonist_ratio
Mercuric chlorideCD38BSK_SAg_CD38_down
Mercuric chlorideCD40BSK_LPS_CD40_down
Mercuric chlorideCD40BSK_SAg_CD40_down
Mercuric chlorideCD69BSK_SAg_CD69_down
Mercuric chlorideNR1I3TOX21_CAR_Antagonist
Mercuric chlorideNR1H4TOX21_FXR_BLA_agonist_ratio
Mercuric chlorideNR1H4TOX21_FXR_BLA_antagonist_ratio

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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.