Clotrimazole

Target genes for Clotrimazole is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
ClotrimazoleNR1H3ATG_LXRa_TRANS_dn
ClotrimazoleNR1H3ATG_DR4_LXR_CIS_dn
ClotrimazoleNACEETOX_H295R_PROG_dn
ClotrimazoleESR1CEETOX_H295R_ESTRONE_dn
ClotrimazoleESR1CEETOX_H295R_ESTRADIOL_dn
ClotrimazoleESR1CEETOX_H295R_TESTO_dn
ClotrimazoleNACEETOX_H295R_ANDR_dn
ClotrimazoleNACEETOX_H295R_TESTO_dn
ClotrimazoleCCL26BSK_4H_Eotaxin3_down
ClotrimazoleCOL3A1BSK_hDFCGF_CollagenIII_down
ClotrimazoleCSF1BSK_LPS_MCSF_down
ClotrimazoleCSF1BSK_CASM3C_MCSF_down
ClotrimazoleCSF1BSK_hDFCGF_MCSF_down
ClotrimazoleCYP1A1NVS_ADME_hCYP1A1
ClotrimazoleCYP2A6NVS_ADME_hCYP2A6
ClotrimazoleCYP2B6NVS_ADME_hCYP2B6
ClotrimazoleCYP2C19NVS_ADME_hCYP2C19
ClotrimazoleCYP2C9NVS_ADME_hCYP2C9
ClotrimazoleCYP2D6NVS_ADME_hCYP2D6
ClotrimazoleCYP3A4NVS_ADME_hCYP3A4
ClotrimazoleCYP19A1TOX21_Aromatase_Inhibition
ClotrimazoleCYP24A1TOX21_VDR_BLA_antagonist_ratio
ClotrimazoleEGR1ATG_EGR_CIS_up
ClotrimazoleAHRTOX21_AhR_LUC_Agonist
ClotrimazoleAHRATG_Ahr_CIS_up
ClotrimazoleESR1CEETOX_H295R_ESTRADIOL_dn
ClotrimazoleESR1CEETOX_H295R_ESTRONE_dn
ClotrimazoleESR1TOX21_ERa_LUC_VM7_Antagonist_0.1nM_E2
ClotrimazoleESR1OT_ERa_EREGFP_0480
ClotrimazoleESR1TOX21_ERa_LUC_VM7_Antagonist_0.5nM_E2
ClotrimazoleESR1ATG_ERE_CIS_up
ClotrimazoleESR1TOX21_ERa_BLA_Antagonist_ratio
ClotrimazoleESR1ATG_ERa_TRANS_up
ClotrimazoleESR1OT_ER_ERaERb_1440
ClotrimazoleESR2TOX21_ERb_BLA_Agonist_ratio
ClotrimazoleESR2TOX21_ERb_BLA_Antagonist_ratio
ClotrimazoleESR2CEETOX_H295R_ESTRONE_dn
ClotrimazoleESR2CEETOX_H295R_ESTRADIOL_dn
ClotrimazoleESR2OT_ER_ERaERb_1440
ClotrimazoleESRRATOX21_PGC_ERR_Antagonist
ClotrimazoleESRRATOX21_ERR_Antagonist
ClotrimazoleF3BSK_LPS_TissueFactor_down
ClotrimazoleF3BSK_CASM3C_TissueFactor_down
ClotrimazoleF3BSK_3C_TissueFactor_down
ClotrimazoleATF6TOX21_ESRE_BLA_ratio
ClotrimazoleFOSATG_AP_1_CIS_up
ClotrimazoleGATA1ATG_GATA_CIS_up
ClotrimazoleNR3C1NVS_NR_hGR
ClotrimazoleNR3C1CEETOX_H295R_DOC_dn
ClotrimazoleNR3C1CEETOX_H295R_CORTISOL_dn
ClotrimazoleNR3C1TOX21_GR_BLA_Antagonist_ratio
ClotrimazoleNR3C1CEETOX_H295R_11DCORT_dn
ClotrimazoleNR3C1TOX21_GR_BLA_Agonist_ratio
ClotrimazoleNR3C1CEETOX_H295R_CORTIC_dn
ClotrimazoleHIF1ATOX21_HRE_BLA_Agonist_ratio
ClotrimazoleHLA-DRABSK_3C_HLADR_down
ClotrimazoleHLA-DRABSK_CASM3C_HLADR_down
ClotrimazoleHLA-DRABSK_BE3C_HLADR_down
ClotrimazoleHSF1TOX21_HSE_BLA_agonist_ratio
ClotrimazoleHSF1ATG_HSE_CIS_up
ClotrimazoleICAM1BSK_KF3CT_ICAM1_down
ClotrimazoleICAM1BSK_3C_ICAM1_down
ClotrimazoleIL1ABSK_LPS_IL1a_down
ClotrimazoleIL1ABSK_KF3CT_IL1a_down
ClotrimazoleIL1ABSK_BE3C_IL1a_down
ClotrimazoleIL6BSK_CASM3C_IL6_down
ClotrimazoleCXCL8BSK_CASM3C_IL8_down
ClotrimazoleCXCL8BSK_hDFCGF_IL8_down
ClotrimazoleCXCL8BSK_3C_IL8_down
ClotrimazoleCXCL8BSK_SAg_IL8_down
ClotrimazoleCXCL8BSK_LPS_IL8_down
ClotrimazoleCXCL10BSK_KF3CT_IP10_down
ClotrimazoleCXCL10BSK_BE3C_IP10_down
ClotrimazoleCXCL10BSK_hDFCGF_IP10_down
ClotrimazoleIRF1ATG_ISRE_CIS_dn
ClotrimazoleARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
ClotrimazoleARCEETOX_H295R_ANDR_dn
ClotrimazoleARACEA_AR_antagonist_80hr
ClotrimazoleAROT_AR_ARSRC1_0960
ClotrimazoleARTOX21_AR_BLA_Agonist_ratio
ClotrimazoleARTOX21_AR_LUC_MDAKB2_Antagonist_10nM_R1881
ClotrimazoleAROT_AR_ARSRC1_0480
ClotrimazoleARTOX21_AR_BLA_Antagonist_ratio
ClotrimazoleARCEETOX_H295R_TESTO_dn
ClotrimazoleJUNATG_AP_1_CIS_up
ClotrimazoleJUNTOX21_AP1_BLA_Agonist_ratio
ClotrimazoleLDLRBSK_CASM3C_LDLR_down
ClotrimazoleESR1CEETOX_H295R_ESTRONE_dn
ClotrimazoleESR1CEETOX_H295R_ESTRADIOL_dn
ClotrimazoleESR1CEETOX_H295R_TESTO_dn
ClotrimazoleFOSTOX21_AP1_BLA_Agonist_ratio
ClotrimazoleNACEETOX_H295R_ESTRONE_dn
ClotrimazoleNACEETOX_H295R_ESTRADIOL_dn
ClotrimazoleNACEETOX_H295R_TESTO_dn
ClotrimazoleSMAD1ATG_BRE_CIS_up
ClotrimazoleARCEETOX_H295R_ANDR_dn
ClotrimazoleARCEETOX_H295R_TESTO_dn
ClotrimazoleCXCL9BSK_BE3C_MIG_down
ClotrimazoleCXCL9BSK_3C_MIG_down
ClotrimazoleCXCL9BSK_CASM3C_MIG_down
ClotrimazoleCXCL9BSK_SAg_MIG_down
ClotrimazoleCXCL9BSK_hDFCGF_MIG_down
ClotrimazoleNR3C2CEETOX_H295R_11DCORT_dn
ClotrimazoleNR3C2CEETOX_H295R_CORTISOL_dn
ClotrimazoleNR3C2CEETOX_H295R_DOC_dn
ClotrimazoleNR3C2CEETOX_H295R_CORTIC_dn
ClotrimazoleMMP1BSK_BE3C_MMP1_down
ClotrimazoleMMP1BSK_hDFCGF_MMP1_down
ClotrimazoleMMP9BSK_KF3CT_MMP9_down
ClotrimazoleMTF1ATG_MRE_CIS_up
ClotrimazoleNFE2L2ATG_NRF2_ARE_CIS_up
ClotrimazoleNFE2L2TOX21_ARE_BLA_agonist_ratio
ClotrimazoleNFKB1TOX21_NFkB_BLA_agonist_ratio
ClotrimazoleNRF1ATG_NRF1_CIS_dn
ClotrimazoleOPRM1NVS_GPCR_hOpiate_mu
ClotrimazoleSERPINE1BSK_BE3C_PAI1_down
ClotrimazoleSERPINE1BSK_hDFCGF_PAI1_down
ClotrimazolePAX6ATG_Pax6_CIS_up
ClotrimazoleLEF1ATG_TCF_b_cat_CIS_dn
ClotrimazolePGRCEETOX_H295R_OHPREG_dn
ClotrimazolePGRTOX21_PR_BLA_Antagonist_ratio
ClotrimazolePGRTOX21_PR_BLA_Agonist_ratio
ClotrimazolePGRCEETOX_H295R_PROG_dn
ClotrimazolePGRCEETOX_H295R_OHPROG_dn
ClotrimazolePLATBSK_BE3C_tPA_down
ClotrimazolePLAUBSK_KF3CT_uPA_down
ClotrimazolePLAUBSK_BE3C_uPA_down
ClotrimazolePLAURBSK_CASM3C_uPAR_down
ClotrimazolePLAURBSK_4H_uPAR_down
ClotrimazolePLAURBSK_BE3C_uPAR_down
ClotrimazolePLAURBSK_3C_uPAR_down
ClotrimazolePOU2F1ATG_Oct_MLP_CIS_up
ClotrimazolePPARDTOX21_PPARd_BLA_antagonist_ratio
ClotrimazolePPARDTOX21_PPARd_BLA_agonist_ratio
ClotrimazolePPARGTOX21_PPARg_BLA_Agonist_ratio
ClotrimazolePPARGTOX21_PPARg_BLA_antagonist_ratio
ClotrimazolePTGER2BSK_LPS_PGE2_down
ClotrimazoleRORAATG_RORE_CIS_up
ClotrimazoleRORBATG_RORE_CIS_up
ClotrimazoleRORCATG_RORE_CIS_up
ClotrimazoleRXRAOT_NURR1_NURR1RXRa_0480
ClotrimazoleSAA1BSK_CASM3C_SAA_down
ClotrimazoleCCL2BSK_LPS_MCP1_down
ClotrimazoleCCL2BSK_3C_MCP1_down
ClotrimazoleCCL2BSK_SAg_MCP1_down
ClotrimazoleCCL2BSK_CASM3C_MCP1_down
ClotrimazoleCCL2BSK_KF3CT_MCP1_down
ClotrimazoleCCL2BSK_4H_MCP1_down
ClotrimazoleSELEBSK_3C_Eselectin_down
ClotrimazoleSELEBSK_SAg_Eselectin_down
ClotrimazoleSELEBSK_LPS_Eselectin_down
ClotrimazoleSELPBSK_4H_Pselectin_down
ClotrimazoleSLC5A5NIS_RAIU_inhibition
ClotrimazoleSOX1ATG_Sox_CIS_up
ClotrimazoleSREBF1ATG_SREBP_CIS_up
ClotrimazoleTCF7ATG_TCF_b_cat_CIS_dn
ClotrimazoleTCF7L2ATG_TCF_b_cat_CIS_dn
ClotrimazoleTGFB1BSK_BE3C_TGFb1_down
ClotrimazoleTGFB1BSK_KF3CT_TGFb1_down
ClotrimazoleTHBDBSK_CASM3C_Thrombomodulin_up
ClotrimazoleTHBDBSK_3C_Thrombomodulin_up
ClotrimazoleTIMP1BSK_hDFCGF_TIMP1_down
ClotrimazoleTIMP2BSK_KF3CT_TIMP2_down
ClotrimazoleTNFBSK_LPS_TNFa_down
ClotrimazoleTP53TOX21_p53_BLA_p2_ratio
ClotrimazoleTP53TOX21_p53_BLA_p1_ratio
ClotrimazoleTP53APR_HepG2_p53Act_72h_up
ClotrimazoleTP53TOX21_p53_BLA_p5_ratio
ClotrimazoleTP53TOX21_p53_BLA_p3_ratio
ClotrimazoleTP53TOX21_p53_BLA_p4_ratio
ClotrimazoleTSHRTOX21_TSHR_Antagonist_ratio
ClotrimazoleNR1H2ATG_DR4_LXR_CIS_dn
ClotrimazoleVCAM1BSK_hDFCGF_VCAM1_down
ClotrimazoleVCAM1BSK_CASM3C_VCAM1_down
ClotrimazoleVCAM1BSK_3C_VCAM1_down
ClotrimazoleVCAM1BSK_LPS_VCAM1_down
ClotrimazoleVCAM1BSK_4H_VCAM1_down
ClotrimazoleVDRTOX21_VDR_BLA_antagonist_ratio
ClotrimazoleVDRATG_VDRE_CIS_up
ClotrimazoleNACEETOX_H295R_ANDR_dn
ClotrimazoleNACEETOX_H295R_TESTO_dn
ClotrimazoleXBP1ATG_Xbp1_CIS_up
ClotrimazoleTCF7L1ATG_TCF_b_cat_CIS_dn
ClotrimazoleNR1I2ATG_PXR_TRANS_up
ClotrimazoleNR1I2ATG_PXRE_CIS_up
ClotrimazoleCD38BSK_SAg_CD38_down
ClotrimazoleCD40BSK_LPS_CD40_down
ClotrimazoleCD40BSK_SAg_CD40_down
ClotrimazoleCD69BSK_SAg_CD69_down
ClotrimazoleNR1I3TOX21_CAR_Antagonist
ClotrimazoleNR1I3ATG_PBREM_CIS_up
ClotrimazoleNR1I3TOX21_CAR_Agonist
ClotrimazoleNR1H4TOX21_FXR_BLA_agonist_ratio
ClotrimazoleNR1H4ATG_FXR_TRANS_up
ClotrimazoleNR1H4OT_FXR_FXRSRC1_0480
ClotrimazoleNR1H4OT_FXR_FXRSRC1_1440
ClotrimazoleNR1H4TOX21_FXR_BLA_antagonist_ratio

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