Butylated hydroxytoluene

Target genes for Butylated hydroxytoluene is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
Butylated hydroxytolueneNR1H3ATG_DR4_LXR_CIS_dn
Butylated hydroxytolueneCYP19A1TOX21_Aromatase_Inhibition
Butylated hydroxytolueneESR1OT_ER_ERaERb_0480
Butylated hydroxytolueneESR1OT_ER_ERaERb_1440
Butylated hydroxytolueneESR1ATG_ERa_TRANS_up
Butylated hydroxytolueneESR2OT_ER_ERaERb_0480
Butylated hydroxytolueneESR2OT_ER_ERaERb_1440
Butylated hydroxytolueneESRRAATG_ERRa_TRANS_up
Butylated hydroxytolueneETS1ATG_Ets_CIS_dn
Butylated hydroxytolueneFOSATG_AP_1_CIS_up
Butylated hydroxytolueneGATA1ATG_GATA_CIS_dn
Butylated hydroxytolueneNR3C1ATG_GR_TRANS_up
Butylated hydroxytolueneHNF4AATG_HNF4a_TRANS_dn
Butylated hydroxytolueneARACEA_AR_antagonist_80hr
Butylated hydroxytolueneAROT_AR_ARSRC1_0480
Butylated hydroxytolueneAROT_AR_ARSRC1_0960
Butylated hydroxytolueneJUNATG_AP_1_CIS_up
Butylated hydroxytolueneJUNTOX21_AP1_BLA_Agonist_ratio
Butylated hydroxytolueneFOSTOX21_AP1_BLA_Agonist_ratio
Butylated hydroxytolueneMTF1ATG_MRE_CIS_up
Butylated hydroxytolueneMYCATG_Myc_CIS_up
Butylated hydroxytolueneNFIAATG_NFI_CIS_up
Butylated hydroxytolueneNFE2L2ATG_NRF2_ARE_CIS_up
Butylated hydroxytoluenePOU2F1ATG_Oct_MLP_CIS_up
Butylated hydroxytolueneRARAATG_DR5_CIS_up
Butylated hydroxytolueneRARAATG_RARa_TRANS_up
Butylated hydroxytolueneRARBATG_DR5_CIS_up
Butylated hydroxytolueneRARBATG_RARb_TRANS_up
Butylated hydroxytolueneRARGATG_DR5_CIS_up
Butylated hydroxytolueneRORCATG_RORg_TRANS_dn
Butylated hydroxytolueneRXRAATG_RXRa_TRANS_up
Butylated hydroxytolueneRXRAOT_NURR1_NURR1RXRa_1440
Butylated hydroxytolueneRXRATOX21_RXR_BLA_Agonist_ratio
Butylated hydroxytolueneRXRAOT_NURR1_NURR1RXRa_0480
Butylated hydroxytolueneRXRBATG_RXRb_TRANS_up
Butylated hydroxytolueneSP1ATG_Sp1_CIS_up
Butylated hydroxytolueneSREBF1ATG_SREBP_CIS_up
Butylated hydroxytolueneTSHRTOX21_TSHR_Agonist_ratio
Butylated hydroxytolueneNR1H2ATG_DR4_LXR_CIS_dn
Butylated hydroxytolueneUSF1ATG_E_Box_CIS_dn
Butylated hydroxytolueneXBP1ATG_Xbp1_CIS_up
Butylated hydroxytolueneNR1I2ATG_PXR_TRANS_up
Butylated hydroxytolueneNR1I2ATG_PXRE_CIS_up
Butylated hydroxytolueneNR1H4OT_FXR_FXRSRC1_0480
Butylated hydroxytolueneNR1H4OT_FXR_FXRSRC1_1440

DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.