Emodin

Target genes for Emodin is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
EmodinNR1H3ATG_DR4_LXR_CIS_dn
EmodinCREB3ATG_CRE_CIS_up
EmodinCEBPBATG_C_EBP_CIS_up
EmodinCYP19A1TOX21_Aromatase_Inhibition
EmodinAHRATG_Ahr_CIS_up
EmodinAHRTOX21_AhR_LUC_Agonist
EmodinESR1TOX21_ERa_BLA_Agonist_ratio
EmodinESR1TOX21_ERa_LUC_VM7_Agonist
EmodinESR1ATG_ERE_CIS_up
EmodinESR1TOX21_ERa_LUC_VM7_Antagonist_0.5nM_E2
EmodinESR1TOX21_ERa_BLA_Antagonist_ratio
EmodinESR1ACEA_ER_80hr
EmodinESR1TOX21_ERa_LUC_VM7_Antagonist_0.1nM_E2
EmodinESR1ATG_ERa_TRANS_up
EmodinESR1NVS_NR_hER
EmodinESR2TOX21_ERb_BLA_Antagonist_ratio
EmodinESR2TOX21_ERb_BLA_Agonist_ratio
EmodinESRRATOX21_PGC_ERR_Antagonist
EmodinESRRATOX21_ERR_Antagonist
EmodinETS1ATG_Ets_CIS_dn
EmodinFOXO1ATG_FoxO_CIS_dn
EmodinFOXO3ATG_FoxO_CIS_dn
EmodinNR3C1ATG_GRE_CIS_dn
EmodinNR3C1TOX21_GR_BLA_Antagonist_ratio
EmodinHDAC1TOX21_HDAC_Inhibition
EmodinIRF1ATG_ISRE_CIS_dn
EmodinARTOX21_AR_BLA_Antagonist_ratio
EmodinARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
EmodinSMAD1ATG_BRE_CIS_up
EmodinMTF1ATG_MRE_CIS_up
EmodinNFIAATG_NFI_CIS_up
EmodinNFE2L2ATG_NRF2_ARE_CIS_up
EmodinNFE2L2TOX21_ARE_BLA_agonist_ratio
EmodinNFKB1ATG_NF_kB_CIS_up
EmodinPGRTOX21_PR_BLA_Antagonist_ratio
EmodinPOU2F1ATG_Oct_MLP_CIS_up
EmodinPPARAATG_PPARa_TRANS_up
EmodinPPARAATG_PPRE_CIS_up
EmodinPPARDATG_PPRE_CIS_up
EmodinPPARGATG_PPARg_TRANS_up
EmodinPPARGATG_PPRE_CIS_up
EmodinPPARGTOX21_PPARg_BLA_antagonist_ratio
EmodinRARAATG_DR5_CIS_up
EmodinRARBATG_DR5_CIS_up
EmodinRARGATG_DR5_CIS_up
EmodinRORAATG_RORE_CIS_up
EmodinRORBATG_RORE_CIS_up
EmodinRORCATG_RORE_CIS_up
EmodinSOX1ATG_Sox_CIS_up
EmodinSP1ATG_Sp1_CIS_up
EmodinTHRAATG_THRa1_TRANS_up
EmodinTP53TOX21_p53_BLA_p4_ratio
EmodinTP53TOX21_p53_BLA_p1_ratio
EmodinTP53TOX21_p53_BLA_p3_ratio
EmodinTP53TOX21_p53_BLA_p5_ratio
EmodinTP53TOX21_p53_BLA_p2_ratio
EmodinNR1H2ATG_DR4_LXR_CIS_dn
EmodinVDRATG_VDRE_CIS_up
EmodinXBP1ATG_Xbp1_CIS_up
EmodinNR1I2ATG_PXRE_CIS_up
EmodinNR1I2ATG_PXR_TRANS_up
EmodinNR1I3TOX21_CAR_Agonist
EmodinNR1I3ATG_PBREM_CIS_up
EmodinNR1H4TOX21_FXR_BLA_antagonist_ratio

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