Fipronil

Target genes for Fipronil is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
FipronilNR1H3ATG_DR4_LXR_CIS_dn
FipronilNR1H3ATG_LXRa_TRANS_up
FipronilCCL26BSK_4H_Eotaxin3_down
FipronilCREB3ATG_CRE_CIS_up
FipronilCEBPBATG_C_EBP_CIS_up
FipronilCSF1BSK_LPS_MCSF_down
FipronilCSF1BSK_CASM3C_MCSF_down
FipronilCYP2B6CLD_CYP2B6_48hr
FipronilCYP2B6CLD_CYP2B6_6hr
FipronilCYP2B6CLD_CYP2B6_24hr
FipronilCYP2C19NVS_ADME_hCYP2C19
FipronilCYP2C9NVS_ADME_hCYP2C9
FipronilCYP3A4CLD_CYP3A4_48hr
FipronilCYP3A4CLD_CYP3A4_24hr
FipronilCYP19A1TOX21_Aromatase_Inhibition
FipronilDIO1NHEERL_MED_hDIO1_dn
FipronilEGFRBSK_hDFCGF_EGFR_up
FipronilEGR1ATG_EGR_CIS_up
FipronilESR1ATG_ERE_CIS_up
FipronilESR1TOX21_ERa_BLA_Antagonist_ratio
FipronilESR1TOX21_ERa_LUC_VM7_Antagonist_0.5nM_E2
FipronilESR1ATG_ERa_TRANS_up
FipronilESR1TOX21_ERa_LUC_VM7_Antagonist_0.1nM_E2
FipronilESR2TOX21_ERb_BLA_Antagonist_ratio
FipronilESRRATOX21_ERR_Antagonist
FipronilESRRATOX21_PGC_ERR_Antagonist
FipronilETS1ATG_Ets_CIS_dn
FipronilFOSATG_AP_1_CIS_up
FipronilNR3C1TOX21_GR_BLA_Antagonist_ratio
FipronilNR3C1ATG_GRE_CIS_dn
FipronilGSTA2CLD_GSTA2_48hr
FipronilHLA-DRABSK_3C_HLADR_down
FipronilHLA-DRABSK_BE3C_HLADR_down
FipronilONECUT1ATG_HNF6_CIS_dn
FipronilHSF1ATG_HSE_CIS_up
FipronilCXCL8BSK_3C_IL8_down
FipronilCXCL8BSK_LPS_IL8_down
FipronilCXCL8BSK_SAg_IL8_down
FipronilCXCL10BSK_KF3CT_IP10_down
FipronilCXCL10BSK_BE3C_IP10_down
FipronilCXCL10BSK_hDFCGF_IP10_down
FipronilIRF1ATG_ISRE_CIS_dn
FipronilARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
FipronilAROT_AR_ARSRC1_0960
FipronilARACEA_AR_antagonist_80hr
FipronilARTOX21_AR_BLA_Antagonist_ratio
FipronilARTOX21_AR_LUC_MDAKB2_Antagonist_10nM_R1881
FipronilJUNATG_AP_1_CIS_up
FipronilKDRBSK_4H_VEGFRII_down
FipronilSMAD1ATG_BRE_CIS_up
FipronilCXCL9BSK_SAg_MIG_down
FipronilCXCL9BSK_BE3C_MIG_down
FipronilMTF1ATG_MRE_CIS_up
FipronilNFE2L2TOX21_ARE_BLA_agonist_ratio
FipronilNFE2L2ATG_NRF2_ARE_CIS_up
FipronilNFKB1ATG_NF_kB_CIS_up
FipronilSERPINE1BSK_BE3C_PAI1_down
FipronilPAX6ATG_Pax6_CIS_up
FipronilPGRTOX21_PR_BLA_Antagonist_ratio
FipronilABCB1CLD_ABCB1_48hr
FipronilPLAURBSK_3C_uPAR_down
FipronilPLAURBSK_4H_uPAR_down
FipronilPOU2F1ATG_Oct_MLP_CIS_up
FipronilPPARAATG_PPRE_CIS_up
FipronilPPARDTOX21_PPARd_BLA_antagonist_ratio
FipronilPPARDATG_PPRE_CIS_up
FipronilPPARGATG_PPARg_TRANS_up
FipronilPPARGATG_PPRE_CIS_up
FipronilRARAATG_RARa_TRANS_up
FipronilRARAATG_DR5_CIS_up
FipronilRARBATG_DR5_CIS_up
FipronilRARGATG_DR5_CIS_up
FipronilRORAATG_RORE_CIS_up
FipronilRORBATG_RORE_CIS_up
FipronilRORCATG_RORE_CIS_up
FipronilCCL2BSK_SAg_MCP1_down
FipronilCCL2BSK_4H_MCP1_down
FipronilCCL2BSK_LPS_MCP1_down
FipronilCCL2BSK_3C_MCP1_down
FipronilSELEBSK_LPS_Eselectin_down
FipronilSELEBSK_3C_Eselectin_down
FipronilSELEBSK_SAg_Eselectin_down
FipronilSELPBSK_4H_Pselectin_down
FipronilSLC5A5NIS_RAIU_inhibition
FipronilSP1ATG_Sp1_CIS_up
FipronilSULT2A1CLD_SULT2A_24hr
FipronilSULT2A1CLD_SULT2A_48hr
FipronilTHBDBSK_CASM3C_Thrombomodulin_up
FipronilTHRAATG_THRa1_TRANS_up
FipronilTNFBSK_LPS_TNFa_up
FipronilNR1H2ATG_DR4_LXR_CIS_dn
FipronilNR1H2ATG_LXRb_TRANS_up
FipronilUSF1ATG_E_Box_CIS_dn
FipronilVCAM1BSK_LPS_VCAM1_down
FipronilVCAM1BSK_CASM3C_VCAM1_down
FipronilVCAM1BSK_4H_VCAM1_down
FipronilVDRATG_VDRE_CIS_up
FipronilXBP1ATG_Xbp1_CIS_up
FipronilNR1I2ATG_PXRE_CIS_up
FipronilNR1I2ATG_PXR_TRANS_up
FipronilABCG2CLD_ABCG2_48hr
FipronilCD38BSK_SAg_CD38_down
FipronilCD40BSK_SAg_CD40_down
FipronilCD40BSK_LPS_CD40_down
FipronilCD69BSK_SAg_CD69_down
FipronilNR1I3NVS_NR_hCAR_Antagonist
FipronilNR1I3ATG_PBREM_CIS_up
FipronilNR1I3TOX21_CAR_Antagonist
FipronilNR1H4OT_FXR_FXRSRC1_1440
FipronilNR1H4TOX21_FXR_BLA_antagonist_ratio
FipronilNR1H4OT_FXR_FXRSRC1_0480

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