Flutamide

Target genes for Flutamide is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
FlutamideNR1H3ATG_LXRa_TRANS_up
FlutamideCREB3ATG_CRE_CIS_up
FlutamideCOL3A1BSK_hDFCGF_CollagenIII_down
FlutamideCYP1A2NVS_ADME_hCYP1A2
FlutamideCYP2C19NVS_ADME_hCYP2C19
FlutamideCYP19A1TOX21_Aromatase_Inhibition
FlutamideAHRATG_Ahr_CIS_dn
FlutamideESR1TOX21_ERa_LUC_VM7_Antagonist_0.1nM_E2
FlutamideESR1TOX21_ERa_BLA_Antagonist_ratio
FlutamideESR1TOX21_ERa_LUC_VM7_Antagonist_0.5nM_E2
FlutamideESR1ACEA_ER_80hr
FlutamideESR2TOX21_ERb_BLA_Antagonist_ratio
FlutamideESRRATOX21_ERR_Antagonist
FlutamideESRRATOX21_PGC_ERR_Antagonist
FlutamideETS1ATG_Ets_CIS_dn
FlutamideFOSATG_AP_1_CIS_up
FlutamideHLA-DRABSK_3C_HLADR_down
FlutamideHSF1ATG_HSE_CIS_up
FlutamideHTR6NVS_GPCR_h5HT6
FlutamideCXCL10BSK_hDFCGF_IP10_down
FlutamideARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
FlutamideAROT_AR_ARSRC1_0960
FlutamideARTOX21_AR_LUC_MDAKB2_Antagonist_10nM_R1881
FlutamideAROT_AR_ARSRC1_0480
FlutamideARNVS_NR_hAR
FlutamideARTOX21_AR_BLA_Antagonist_ratio
FlutamideJUNATG_AP_1_CIS_up
FlutamideLDLRBSK_CASM3C_LDLR_down
FlutamideSMAD1ATG_BRE_CIS_up
FlutamideMMP2NVS_ENZ_hMMP2
FlutamideMMP7NVS_ENZ_hMMP7
FlutamideMTF1ATG_MRE_CIS_up
FlutamideNFE2L2TOX21_ARE_BLA_agonist_ratio
FlutamideNFE2L2ATG_NRF2_ARE_CIS_up
FlutamideNFKB1ATG_NF_kB_CIS_up
FlutamideNR4A2ATG_NURR1_TRANS_up
FlutamideLEF1ATG_TCF_b_cat_CIS_up
FlutamidePGRTOX21_PR_BLA_Antagonist_ratio
FlutamidePOU2F1ATG_Oct_MLP_CIS_up
FlutamidePPARAATG_PPRE_CIS_up
FlutamidePPARDATG_PPRE_CIS_up
FlutamidePPARGATG_PPRE_CIS_up
FlutamidePPARGATG_PPARg_TRANS_up
FlutamideRXRBATG_RXRb_TRANS_up
FlutamideSLC5A5NIS_RAIU_inhibition
FlutamideTBXA2RNVS_GPCR_hTXA2
FlutamideTCF7ATG_TCF_b_cat_CIS_up
FlutamideTCF7L2ATG_TCF_b_cat_CIS_up
FlutamideTSPONVS_MP_hPBR
FlutamideTHRAATG_THRa1_TRANS_up
FlutamideTP53APR_HepG2_p53Act_24h_up
FlutamideTP53TOX21_p53_BLA_p2_ratio
FlutamideTP53TOX21_p53_BLA_p3_ratio
FlutamideTP53APR_HepG2_p53Act_72h_up
FlutamideTP53ATG_p53_CIS_up
FlutamideUSF1ATG_E_Box_CIS_dn
FlutamideVDRATG_VDRE_CIS_up
FlutamideXBP1ATG_Xbp1_CIS_up
FlutamideTCF7L1ATG_TCF_b_cat_CIS_up
FlutamideNR1I2ATG_PXRE_CIS_up
FlutamideNR1I2ATG_PXR_TRANS_up
FlutamideCD38BSK_SAg_CD38_down
FlutamideCD40BSK_SAg_CD40_down
FlutamideCD69BSK_SAg_CD69_down
FlutamideNR1I3ATG_PBREM_CIS_up
FlutamideNR1I3ATG_CAR_TRANS_dn
FlutamideNR1H4OT_FXR_FXRSRC1_1440

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