Heptachlor

Target genes for Heptachlor is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
HeptachlorNR1H3ATG_DR4_LXR_CIS_dn
HeptachlorCCL26BSK_4H_Eotaxin3_down
HeptachlorCOL3A1BSK_hDFCGF_CollagenIII_down
HeptachlorCSF1BSK_hDFCGF_MCSF_down
HeptachlorCSF1BSK_CASM3C_MCSF_down
HeptachlorCSF1BSK_LPS_MCSF_down
HeptachlorCYP19A1TOX21_Aromatase_Inhibition
HeptachlorEGR1ATG_EGR_CIS_up
HeptachlorESR1ATG_ERE_CIS_up
HeptachlorESR2TOX21_ERb_BLA_Antagonist_ratio
HeptachlorESRRAATG_ERRa_TRANS_dn
HeptachlorESRRATOX21_ERR_Antagonist
HeptachlorESRRGATG_ERRg_TRANS_dn
HeptachlorF3BSK_3C_TissueFactor_down
HeptachlorF3BSK_LPS_TissueFactor_down
HeptachlorF3BSK_CASM3C_TissueFactor_down
HeptachlorATF6TOX21_ESRE_BLA_ratio
HeptachlorFOSATG_AP_1_CIS_up
HeptachlorNR3C1TOX21_GR_BLA_Agonist_ratio
HeptachlorHIF1ATOX21_HRE_BLA_Agonist_ratio
HeptachlorHLA-DRABSK_3C_HLADR_down
HeptachlorHLA-DRABSK_BE3C_HLADR_down
HeptachlorHLA-DRABSK_CASM3C_HLADR_down
HeptachlorICAM1BSK_3C_ICAM1_down
HeptachlorICAM1BSK_KF3CT_ICAM1_down
HeptachlorIL1ABSK_KF3CT_IL1a_down
HeptachlorIL1ABSK_LPS_IL1a_down
HeptachlorIL1ABSK_BE3C_IL1a_down
HeptachlorIL6BSK_CASM3C_IL6_down
HeptachlorCXCL8BSK_SAg_IL8_down
HeptachlorCXCL8BSK_CASM3C_IL8_down
HeptachlorCXCL8BSK_3C_IL8_down
HeptachlorCXCL8BSK_LPS_IL8_down
HeptachlorCXCL8BSK_hDFCGF_IL8_down
HeptachlorCXCL10BSK_BE3C_IP10_down
HeptachlorCXCL10BSK_hDFCGF_IP10_down
HeptachlorCXCL10BSK_KF3CT_IP10_down
HeptachlorIRF1ATG_ISRE_CIS_dn
HeptachlorARACEA_AR_antagonist_80hr
HeptachlorARTOX21_AR_BLA_Agonist_ratio
HeptachlorAROT_AR_ARSRC1_0480
HeptachlorARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
HeptachlorAROT_AR_ARSRC1_0960
HeptachlorARATG_AR_TRANS_up
HeptachlorJUNTOX21_AP1_BLA_Agonist_ratio
HeptachlorJUNATG_AP_1_CIS_up
HeptachlorKDRBSK_4H_VEGFRII_down
HeptachlorLDLRBSK_CASM3C_LDLR_down
HeptachlorFOSTOX21_AP1_BLA_Agonist_ratio
HeptachlorCXCL9BSK_CASM3C_MIG_down
HeptachlorCXCL9BSK_3C_MIG_down
HeptachlorCXCL9BSK_SAg_MIG_down
HeptachlorCXCL9BSK_hDFCGF_MIG_down
HeptachlorMMP1BSK_hDFCGF_MMP1_down
HeptachlorMMP9BSK_KF3CT_MMP9_down
HeptachlorMTF1ATG_MRE_CIS_up
HeptachlorMYCATG_Myc_CIS_up
HeptachlorNFIAATG_NFI_CIS_up
HeptachlorNFE2L2TOX21_ARE_BLA_agonist_ratio
HeptachlorNFKB1TOX21_NFkB_BLA_agonist_ratio
HeptachlorNFKB1ATG_NF_kB_CIS_dn
HeptachlorSERPINE1BSK_hDFCGF_PAI1_down
HeptachlorSERPINE1BSK_BE3C_PAI1_down
HeptachlorPAX6ATG_Pax6_CIS_up
HeptachlorPGRTOX21_PR_BLA_Antagonist_ratio
HeptachlorPLATBSK_BE3C_tPA_down
HeptachlorPLAUBSK_KF3CT_uPA_down
HeptachlorPLAURBSK_4H_uPAR_down
HeptachlorPLAURBSK_CASM3C_uPAR_down
HeptachlorPLAURBSK_3C_uPAR_down
HeptachlorPOU2F1ATG_Oct_MLP_CIS_up
HeptachlorRORCATG_RORg_TRANS_dn
HeptachlorRXRAOT_NURR1_NURR1RXRa_0480
HeptachlorSAA1BSK_CASM3C_SAA_down
HeptachlorCCL2BSK_3C_MCP1_down
HeptachlorCCL2BSK_LPS_MCP1_down
HeptachlorCCL2BSK_4H_MCP1_down
HeptachlorCCL2BSK_CASM3C_MCP1_down
HeptachlorCCL2BSK_KF3CT_MCP1_down
HeptachlorCCL2BSK_SAg_MCP1_down
HeptachlorSELEBSK_SAg_Eselectin_down
HeptachlorSELEBSK_LPS_Eselectin_down
HeptachlorSELEBSK_3C_Eselectin_down
HeptachlorSELPBSK_4H_Pselectin_down
HeptachlorSLC5A5NIS_RAIU_inhibition
HeptachlorSP1ATG_Sp1_CIS_up
HeptachlorTGFB1BSK_KF3CT_TGFb1_down
HeptachlorTGFB1BSK_BE3C_TGFb1_down
HeptachlorTIMP1BSK_hDFCGF_TIMP1_down
HeptachlorTIMP2BSK_KF3CT_TIMP2_down
HeptachlorTNFBSK_LPS_TNFa_down
HeptachlorTP53TOX21_p53_BLA_p1_ratio
HeptachlorTP53ATG_p53_CIS_dn
HeptachlorTP53APR_HepG2_p53Act_24h_up
HeptachlorTP53APR_HepG2_p53Act_72h_up
HeptachlorTSHRTOX21_TSHR_Agonist_ratio
HeptachlorNR1H2ATG_DR4_LXR_CIS_dn
HeptachlorVCAM1BSK_hDFCGF_VCAM1_down
HeptachlorVCAM1BSK_4H_VCAM1_down
HeptachlorVCAM1BSK_3C_VCAM1_down
HeptachlorVCAM1BSK_LPS_VCAM1_down
HeptachlorVCAM1BSK_CASM3C_VCAM1_down
HeptachlorNR1I2ATG_PXRE_CIS_up
HeptachlorNR1I2ATG_PXR_TRANS_up
HeptachlorCD38BSK_SAg_CD38_down
HeptachlorCD40BSK_SAg_CD40_down
HeptachlorCD40BSK_LPS_CD40_down
HeptachlorCD69BSK_SAg_CD69_down
HeptachlorNR1I3TOX21_CAR_Agonist
HeptachlorNR1I3ATG_CAR_TRANS_dn
HeptachlorNR1H4TOX21_FXR_BLA_antagonist_ratio
HeptachlorNR1H4ATG_IR1_CIS_dn
HeptachlorNR1H4ATG_FXR_TRANS_up
HeptachlorNR1H4OT_FXR_FXRSRC1_0480

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