Hexylresorcinol

Target genes for Hexylresorcinol is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
HexylresorcinolNR1H3ATG_DR4_LXR_CIS_dn
HexylresorcinolCCL26BSK_4H_Eotaxin3_down
HexylresorcinolCREB3ATG_CRE_CIS_up
HexylresorcinolCOL3A1BSK_hDFCGF_CollagenIII_down
HexylresorcinolCSF1BSK_LPS_MCSF_down
HexylresorcinolCSF1BSK_hDFCGF_MCSF_down
HexylresorcinolADRA2CNVS_GPCR_hAdra2C
HexylresorcinolADRB1NVS_GPCR_hAdrb1
HexylresorcinolCYP2B6NVS_ADME_hCYP2B6
HexylresorcinolCYP2C19NVS_ADME_hCYP2C19
HexylresorcinolCYP2C9NVS_ADME_hCYP2C9
HexylresorcinolCYP2D6NVS_ADME_hCYP2D6
HexylresorcinolCYP3A4NVS_ADME_hCYP3A4
HexylresorcinolCYP19A1NVS_ADME_hCYP19A1
HexylresorcinolCYP19A1TOX21_Aromatase_Inhibition
HexylresorcinolDIO1NHEERL_MED_hDIO1_dn
HexylresorcinolEGFRBSK_hDFCGF_EGFR_down
HexylresorcinolEGR1ATG_EGR_CIS_up
HexylresorcinolESR1OT_ER_ERaERb_0480
HexylresorcinolESR1TOX21_ERa_LUC_VM7_Agonist
HexylresorcinolESR1ATG_ERa_TRANS_up
HexylresorcinolESR1ATG_ERE_CIS_up
HexylresorcinolESR1OT_ER_ERaERb_1440
HexylresorcinolESR1TOX21_ERa_LUC_VM7_Antagonist_0.1nM_E2
HexylresorcinolESR1TOX21_ERa_BLA_Antagonist_ratio
HexylresorcinolESR1NVS_NR_hER
HexylresorcinolESR2TOX21_ERb_BLA_Antagonist_ratio
HexylresorcinolESR2OT_ER_ERbERb_1440
HexylresorcinolESR2OT_ER_ERaERb_1440
HexylresorcinolESR2OT_ER_ERaERb_0480
HexylresorcinolESR2OT_ER_ERbERb_0480
HexylresorcinolF3BSK_3C_TissueFactor_down
HexylresorcinolNR3C1TOX21_GR_BLA_Agonist_ratio
HexylresorcinolNR3C1NVS_NR_hGR
HexylresorcinolHIF1ATOX21_HRE_BLA_Agonist_ratio
HexylresorcinolHIF1AATG_HIF1a_CIS_up
HexylresorcinolHLA-DRABSK_3C_HLADR_down
HexylresorcinolHLA-DRABSK_BE3C_HLADR_down
HexylresorcinolHLA-DRABSK_CASM3C_HLADR_down
HexylresorcinolHTR5ANVS_GPCR_h5HT5A
HexylresorcinolHTR7NVS_GPCR_h5HT7
HexylresorcinolICAM1BSK_KF3CT_ICAM1_down
HexylresorcinolICAM1BSK_3C_ICAM1_down
HexylresorcinolIL1ABSK_LPS_IL1a_down
HexylresorcinolIL1ABSK_KF3CT_IL1a_down
HexylresorcinolIL1ABSK_BE3C_IL1a_down
HexylresorcinolCXCL8BSK_SAg_IL8_down
HexylresorcinolCXCL8BSK_hDFCGF_IL8_down
HexylresorcinolCXCL8BSK_3C_IL8_down
HexylresorcinolCXCL8BSK_LPS_IL8_down
HexylresorcinolCXCL10BSK_BE3C_IP10_down
HexylresorcinolCXCL10BSK_KF3CT_IP10_down
HexylresorcinolCXCL10BSK_hDFCGF_IP10_down
HexylresorcinolIRF1ATG_ISRE_CIS_dn
HexylresorcinolARNVS_NR_hAR
HexylresorcinolAROT_AR_ARSRC1_0480
HexylresorcinolAROT_AR_ARSRC1_0960
HexylresorcinolARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
HexylresorcinolARTOX21_AR_BLA_Antagonist_ratio
HexylresorcinolARACEA_AR_antagonist_80hr
HexylresorcinolJUNTOX21_AP1_BLA_Agonist_ratio
HexylresorcinolLDLRBSK_CASM3C_LDLR_down
HexylresorcinolFOSTOX21_AP1_BLA_Agonist_ratio
HexylresorcinolSMAD1ATG_BRE_CIS_up
HexylresorcinolCXCL9BSK_SAg_MIG_down
HexylresorcinolCXCL9BSK_hDFCGF_MIG_down
HexylresorcinolCXCL9BSK_3C_MIG_down
HexylresorcinolCXCL9BSK_BE3C_MIG_down
HexylresorcinolMMP1BSK_hDFCGF_MMP1_down
HexylresorcinolMMP9BSK_KF3CT_MMP9_down
HexylresorcinolMTF1ATG_MRE_CIS_up
HexylresorcinolNFE2L2TOX21_ARE_BLA_agonist_ratio
HexylresorcinolNFE2L2ATG_NRF2_ARE_CIS_up
HexylresorcinolNFKB1ATG_NF_kB_CIS_up
HexylresorcinolSERPINE1BSK_hDFCGF_PAI1_down
HexylresorcinolSERPINE1BSK_BE3C_PAI1_down
HexylresorcinolPAX6ATG_Pax6_CIS_up
HexylresorcinolLEF1ATG_TCF_b_cat_CIS_dn
HexylresorcinolPDE4ANVS_ENZ_hPDE4A1
HexylresorcinolPGRTOX21_PR_BLA_Antagonist_ratio
HexylresorcinolPLATBSK_BE3C_tPA_down
HexylresorcinolPLAUBSK_BE3C_uPA_down
HexylresorcinolPLAUBSK_KF3CT_uPA_down
HexylresorcinolPLAURBSK_BE3C_uPAR_down
HexylresorcinolPLAURBSK_3C_uPAR_down
HexylresorcinolPLAURBSK_4H_uPAR_down
HexylresorcinolPOU2F1ATG_Oct_MLP_CIS_up
HexylresorcinolPPARAATG_PPRE_CIS_up
HexylresorcinolPPARDATG_PPRE_CIS_up
HexylresorcinolPPARGATG_PPARg_TRANS_up
HexylresorcinolPPARGATG_PPRE_CIS_up
HexylresorcinolPPARGNVS_NR_hPPARg
HexylresorcinolPPARGTOX21_PPARg_BLA_antagonist_ratio
HexylresorcinolPTGER2BSK_LPS_PGE2_down
HexylresorcinolRORAATG_RORE_CIS_up
HexylresorcinolRORBATG_RORE_CIS_up
HexylresorcinolRORCATG_RORE_CIS_up
HexylresorcinolRXRBATG_RXRb_TRANS_up
HexylresorcinolCCL2BSK_3C_MCP1_down
HexylresorcinolCCL2BSK_SAg_MCP1_down
HexylresorcinolCCL2BSK_LPS_MCP1_down
HexylresorcinolCCL2BSK_KF3CT_MCP1_down
HexylresorcinolCCL2BSK_4H_MCP1_down
HexylresorcinolSELEBSK_3C_Eselectin_down
HexylresorcinolSELEBSK_SAg_Eselectin_down
HexylresorcinolSELPBSK_4H_Pselectin_down
HexylresorcinolSLC5A5NIS_RAIU_inhibition
HexylresorcinolSLC6A2NVS_TR_hNET
HexylresorcinolSLC6A3NVS_TR_hDAT
HexylresorcinolTBXA2RNVS_GPCR_hTXA2
HexylresorcinolTCF7ATG_TCF_b_cat_CIS_dn
HexylresorcinolTCF7L2ATG_TCF_b_cat_CIS_dn
HexylresorcinolTFAP2AATG_AP_2_CIS_dn
HexylresorcinolTFAP2BATG_AP_2_CIS_dn
HexylresorcinolTGFB1BSK_KF3CT_TGFb1_down
HexylresorcinolTGFB1BSK_BE3C_TGFb1_down
HexylresorcinolTHBDBSK_CASM3C_Thrombomodulin_up
HexylresorcinolTIMP1BSK_hDFCGF_TIMP1_down
HexylresorcinolTIMP2BSK_KF3CT_TIMP2_down
HexylresorcinolTNFBSK_LPS_TNFa_down
HexylresorcinolTP53TOX21_p53_BLA_p5_ratio
HexylresorcinolTP53APR_HepG2_p53Act_24h_up
HexylresorcinolTP53TOX21_p53_BLA_p2_ratio
HexylresorcinolTP53TOX21_p53_BLA_p4_ratio
HexylresorcinolNR1H2ATG_DR4_LXR_CIS_dn
HexylresorcinolVCAM1BSK_4H_VCAM1_down
HexylresorcinolVCAM1BSK_hDFCGF_VCAM1_down
HexylresorcinolVCAM1BSK_CASM3C_VCAM1_up
HexylresorcinolVCAM1BSK_3C_VCAM1_down
HexylresorcinolVCAM1BSK_LPS_VCAM1_down
HexylresorcinolVDRATG_VDRE_CIS_up
HexylresorcinolXBP1ATG_Xbp1_CIS_up
HexylresorcinolTCF7L1ATG_TCF_b_cat_CIS_dn
HexylresorcinolTFAP2DATG_AP_2_CIS_dn
HexylresorcinolNR1I2ATG_PXRE_CIS_up
HexylresorcinolNR1I2ATG_PXR_TRANS_up
HexylresorcinolCD38BSK_SAg_CD38_down
HexylresorcinolCD40BSK_LPS_CD40_down
HexylresorcinolCD40BSK_SAg_CD40_down
HexylresorcinolCD69BSK_SAg_CD69_down
HexylresorcinolNR1H4ATG_IR1_CIS_dn
HexylresorcinolNR1H4TOX21_FXR_BLA_antagonist_ratio
HexylresorcinolNR1H4ATG_FXR_TRANS_up
HexylresorcinolNR1H4OT_FXR_FXRSRC1_1440
HexylresorcinolNR1H4NVS_NR_hFXR_Antagonist

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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.