Amitraz

Target genes for Amitraz is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
AmitrazCCL26BSK_4H_Eotaxin3_down
AmitrazCOL3A1BSK_hDFCGF_CollagenIII_down
AmitrazCSF1BSK_LPS_MCSF_down
AmitrazCSF1BSK_CASM3C_MCSF_down
AmitrazCSF1BSK_hDFCGF_MCSF_down
AmitrazADRA2ANVS_GPCR_hAdra2A
AmitrazCYP1A1CLD_CYP1A1_48hr
AmitrazCYP1A2CLD_CYP1A2_48hr
AmitrazCYP2C19NVS_ADME_hCYP2C19
AmitrazCYP19A1TOX21_Aromatase_Inhibition
AmitrazAHRTOX21_AhR_LUC_Agonist
AmitrazESRRATOX21_ERR_Antagonist
AmitrazESRRATOX21_PGC_ERR_Antagonist
AmitrazF3BSK_LPS_TissueFactor_down
AmitrazF3BSK_3C_TissueFactor_down
AmitrazFOXO1ATG_FoxO_CIS_up
AmitrazFOXO3ATG_FoxO_CIS_up
AmitrazHIF1ATOX21_HRE_BLA_Agonist_ratio
AmitrazHLA-DRABSK_3C_HLADR_down
AmitrazHLA-DRABSK_BE3C_HLADR_down
AmitrazHTR7NVS_GPCR_h5HT7
AmitrazICAM1BSK_3C_ICAM1_down
AmitrazIL1ABSK_BE3C_IL1a_down
AmitrazIL1ABSK_LPS_IL1a_down
AmitrazIL6BSK_CASM3C_IL6_up
AmitrazCXCL8BSK_3C_IL8_down
AmitrazCXCL8BSK_hDFCGF_IL8_down
AmitrazCXCL8BSK_LPS_IL8_down
AmitrazCXCL10BSK_BE3C_IP10_down
AmitrazCXCL10BSK_KF3CT_IP10_down
AmitrazCXCL10BSK_hDFCGF_IP10_down
AmitrazARTOX21_AR_BLA_Antagonist_ratio
AmitrazAROT_AR_ARSRC1_0960
AmitrazARACEA_AR_antagonist_80hr
AmitrazARTOX21_AR_LUC_MDAKB2_Antagonist_0.5nM_R1881
AmitrazJUNTOX21_AP1_BLA_Agonist_ratio
AmitrazKDRBSK_4H_VEGFRII_down
AmitrazFOSTOX21_AP1_BLA_Agonist_ratio
AmitrazCXCL9BSK_hDFCGF_MIG_down
AmitrazCXCL9BSK_SAg_MIG_down
AmitrazCXCL9BSK_3C_MIG_down
AmitrazCXCL9BSK_BE3C_MIG_down
AmitrazMMP1BSK_hDFCGF_MMP1_down
AmitrazMMP9BSK_KF3CT_MMP9_down
AmitrazMYBATG_Myb_CIS_up
AmitrazSERPINE1BSK_hDFCGF_PAI1_down
AmitrazSERPINE1BSK_BE3C_PAI1_down
AmitrazABCB1CLD_ABCB1_24hr
AmitrazPLAUBSK_KF3CT_uPA_down
AmitrazPLAURBSK_3C_uPAR_down
AmitrazPLAURBSK_4H_uPAR_down
AmitrazPLAURBSK_BE3C_uPAR_down
AmitrazPOU2F1ATG_Oct_MLP_CIS_up
AmitrazPTGER2BSK_LPS_PGE2_down
AmitrazPTPN11NVS_ENZ_hPTPN11_Activator
AmitrazRARAATG_DR5_CIS_dn
AmitrazRARBATG_DR5_CIS_dn
AmitrazRARGATG_DR5_CIS_dn
AmitrazRXRAOT_NURR1_NURR1RXRa_0480
AmitrazRXRAOT_NURR1_NURR1RXRa_1440
AmitrazSAA1BSK_CASM3C_SAA_down
AmitrazCCL2BSK_3C_MCP1_down
AmitrazCCL2BSK_LPS_MCP1_down
AmitrazCCL2BSK_SAg_MCP1_down
AmitrazCCL2BSK_4H_MCP1_down
AmitrazSELEBSK_LPS_Eselectin_down
AmitrazSELEBSK_3C_Eselectin_down
AmitrazSELEBSK_SAg_Eselectin_down
AmitrazSELPBSK_4H_Pselectin_down
AmitrazSLC5A5NIS_RAIU_inhibition
AmitrazTGFB1BSK_BE3C_TGFb1_down
AmitrazTHBDBSK_3C_Thrombomodulin_up
AmitrazTHBDBSK_CASM3C_Thrombomodulin_up
AmitrazTIMP1BSK_hDFCGF_TIMP1_down
AmitrazTIMP2BSK_KF3CT_TIMP2_down
AmitrazTNFBSK_LPS_TNFa_down
AmitrazVCAM1BSK_4H_VCAM1_down
AmitrazVCAM1BSK_LPS_VCAM1_down
AmitrazVCAM1BSK_CASM3C_VCAM1_up
AmitrazVCAM1BSK_hDFCGF_VCAM1_down
AmitrazVCAM1BSK_3C_VCAM1_down
AmitrazNR1I2ATG_PXRE_CIS_dn
AmitrazABCG2CLD_ABCG2_24hr
AmitrazABCG2CLD_ABCG2_48hr
AmitrazCD38BSK_SAg_CD38_down
AmitrazCD40BSK_SAg_CD40_down
AmitrazCD40BSK_LPS_CD40_down
AmitrazCD69BSK_SAg_CD69_down
AmitrazNR1I3TOX21_CAR_Antagonist
AmitrazNR1H4OT_FXR_FXRSRC1_0480
AmitrazNR1H4TOX21_FXR_BLA_antagonist_ratio

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