Iprodione

Target genes for Iprodione is obtained based on ToxCast assay component endpoints.
Chemical nameGene identifierToxCast assay component endpoint name
IprodioneNACEETOX_H295R_PROG_dn
IprodioneESR1CEETOX_H295R_TESTO_dn
IprodioneNACEETOX_H295R_TESTO_dn
IprodioneNACEETOX_H295R_ANDR_dn
IprodioneCREB3ATG_CRE_CIS_up
IprodioneCOL3A1BSK_hDFCGF_CollagenIII_up
IprodioneCYP1A1CLD_CYP1A1_6hr
IprodioneCYP1A1CLD_CYP1A1_48hr
IprodioneCYP1A1NVS_ADME_hCYP1A1
IprodioneCYP1A1CLD_CYP1A1_24hr
IprodioneCYP1A2CLD_CYP1A2_24hr
IprodioneCYP1A2NVS_ADME_hCYP1A2
IprodioneCYP1A2CLD_CYP1A2_48hr
IprodioneCYP1A2CLD_CYP1A2_6hr
IprodioneCYP2B6CLD_CYP2B6_48hr
IprodioneCYP2B6CLD_CYP2B6_6hr
IprodioneCYP2B6CLD_CYP2B6_24hr
IprodioneCYP2C19NVS_ADME_hCYP2C19
IprodioneCYP2C9NVS_ADME_hCYP2C9
IprodioneCYP2C18NVS_ADME_hCYP2C18
IprodioneCYP3A4CLD_CYP3A4_24hr
IprodioneCYP3A4CLD_CYP3A4_48hr
IprodioneAHRATG_Ahr_CIS_up
IprodioneAHRTOX21_AhR_LUC_Agonist
IprodioneESR1ATG_ERE_CIS_up
IprodioneESR2TOX21_ERb_BLA_Antagonist_ratio
IprodioneESRRATOX21_ERR_Antagonist
IprodioneNR3C1CEETOX_H295R_11DCORT_dn
IprodioneNR3C1CEETOX_H295R_DOC_dn
IprodioneARCEETOX_H295R_ANDR_dn
IprodioneARCEETOX_H295R_TESTO_dn
IprodioneARACEA_AR_antagonist_80hr
IprodioneARTOX21_AR_LUC_MDAKB2_Agonist_3uM_Nilutamide
IprodioneESR1CEETOX_H295R_TESTO_dn
IprodioneNACEETOX_H295R_TESTO_dn
IprodioneARCEETOX_H295R_ANDR_dn
IprodioneARCEETOX_H295R_TESTO_dn
IprodioneNR3C2CEETOX_H295R_11DCORT_dn
IprodioneNR3C2CEETOX_H295R_DOC_dn
IprodioneMMP1BSK_hDFCGF_MMP1_up
IprodioneNFE2L2TOX21_ARE_BLA_agonist_ratio
IprodioneNFE2L2ATG_NRF2_ARE_CIS_up
IprodioneSERPINE1BSK_BE3C_PAI1_down
IprodionePGRTOX21_PR_BLA_Antagonist_ratio
IprodionePGRCEETOX_H295R_OHPROG_dn
IprodionePGRCEETOX_H295R_PROG_dn
IprodionePGRCEETOX_H295R_OHPREG_dn
IprodionePLAURBSK_4H_uPAR_down
IprodionePLAURBSK_3C_uPAR_down
IprodionePOU2F1ATG_Oct_MLP_CIS_up
IprodionePPARAATG_PPRE_CIS_up
IprodionePPARDATG_PPRE_CIS_up
IprodionePPARGATG_PPARg_TRANS_up
IprodionePPARGATG_PPRE_CIS_up
IprodioneRARAATG_RARa_TRANS_up
IprodioneRARAATG_DR5_CIS_up
IprodioneRARBATG_DR5_CIS_up
IprodioneRARGATG_DR5_CIS_up
IprodioneRORAATG_RORE_CIS_up
IprodioneRORBATG_RORE_CIS_up
IprodioneRORCATG_RORE_CIS_up
IprodioneSELEBSK_SAg_Eselectin_up
IprodioneTSPONVS_MP_hPBR
IprodioneVDRATG_VDRE_CIS_up
IprodioneNACEETOX_H295R_TESTO_dn
IprodioneNACEETOX_H295R_ANDR_dn
IprodioneNR1I2ATG_PXR_TRANS_up
IprodioneNR1I2ATG_PXRE_CIS_up
IprodioneCD38BSK_SAg_CD38_up
IprodioneNR1I3ATG_PBREM_CIS_up
IprodioneNR1H4OT_FXR_FXRSRC1_0480
IprodioneNR1H4ATG_IR1_CIS_up

DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.